Evaluation of buffer-radius modelling approaches used in forest conservation and planning

Spatial modelling approaches are increasingly being used to direct forest management and conservation planning at the landscape scale. A popular approach is the use of buffer-radius methods, which create buffers around distinct forest habitat patches to assess habitat connectivity within anthropogenic landscapes. However, the effectiveness and sensitivity of such methods have rarely been evaluated. In this study, Euclidean and least-cost buffer-radius approaches were used to predict functional ecological networks within the wooded landscape of the Isle of Wight (UK). To parameterize the models, a combination of empirical evidence and expert knowledge was used relating to the dispersal ability of a model species, the wood cricket (Nemobius sylvestris Bosc.). Three scenarios were developed to assess the influence of increasing the amount of spatial and species-specific input data on the model outcomes. This revealed that the level of habitat fragmentation for the model species is likely to be underestimated when few empirical data are available. Furthermore, the least-cost buffer approach outperformed simple Euclidean buffer in predicting presence and absence for the model species. Sensitivity analyses on model performance revealed high sensitivity of the models to variation in buffer distance (i.e. maximum dispersal distance) and permeability of common landscape features such as roads, watercourses, grassland and semi-natural habitat. This indicates that when data are lacking with which to parameterize buffer-radius models, the model outcomes need to be interpreted with caution. This study also showed that if sufficient empirical data are available, least-cost buffer approaches have the potential to be a valuable tool to assist forest managers in making informed decisions. However, least-cost approaches should always be used as an indicative rather than prescriptive management tool to support forest landscape conservation and planning

Realistic undulators for intense gamma-ray beams at future colliders

The baseline designs for the ILC and CLIC require the production of an intense flux of gamma rays in their positron sources. In the case of CLIC the gamma rays are produced by a Compton backscattering source, but in this paper we concentrate on undulator-based sources as proposed for the ILC.We present the development of a simulation to generate a magnetic field map based on a Fourier analysis of any measured field map. We have used a field map measured from the ILC helical undulator prototype to calculate the typical distribution of field errors, and used them in our calculations to produce simulated field maps. We show that a loss of gamma ray intensity of ~8% could be expected, compared to the ideal case. This leads to a similar drop in positron production which can be compensated for by increasing the undulator length

Possible uses of gamma-rays at future intense positron sources

The baseline design of the ILC (International Linear Collider) positron source requires the production of an intense flux of gamma rays. In this paper we present an investigation of using the gamma ray beam of the ILC for additional applications, including nuclear physics. As a result of changing the collimator shape, as well as the parameters of the undulator magnets, we obtained spectra from numerical simulations using the HUSR/GSR software package. We present results from simulations and a discussion of possible future investigations in this paper

Field testing a novel high residence positioning system for monitoring the fine‐scale movements of aquatic organisms

1. Acoustic telemetry is an important tool for studying the behaviour of aquatic organisms in the wild. 2. VEMCO high residence (HR) tags and receivers are a recent introduction in the field of acoustic telemetry and can be paired with existing algorithms (e.g. VEMCO positioning system [VPS]) to obtain high‐resolution two‐dimensional positioning data. 3. Here, we present results of the first documented field test of a VPS composed of HR receivers (hereafter, HR‐VPS). We performed a series of stationary and moving trials with HR tags (mean HR transmission period = 1.5 s) to evaluate the precision, accuracy and temporal capabilities of this positioning technology. In addition, we present a sample of data obtained for five European perch Perca fluviatilis implanted with HR tags (mean HR transmission period = 4 s) to illustrate how this technology can estimate the fine‐scale behaviour of aquatic animals. 4. Accuracy and precision estimates (median [5th–95th percentile]) of HR‐VPS positions for all stationary trials were 5.6 m (4.2–10.8 m) and 0.1 m (0.02–0.07 m), respectively, and depended on the location of tags within the receiver array. In moving tests, tracks generated by HR‐VPS closely mimicked those produced by a handheld GPS held over the tag, but these differed in location by an average of ≈9 m. 5. We found that estimates of animal speed and distance travelled for perch declined when positional data for acoustically tagged perch were thinned to mimic longer transmission periods. These data also revealed a trade‐off between capturing real nonlinear animal movements and the inclusion of positioning error. 6. Our results suggested that HR‐VPS can provide more representative estimates of movement metrics and offer an advancement for studying fine‐scale movements of aquatic organisms, but high‐precision survey techniques may be needed to test these systems

Vertical stiffness asymmetries during drop jumping are related to ankle stiffness asymmetries

Asymmetry in vertical stiffness has been associated with increased injury incidence and impaired performance. The determinants of vertical stiffness asymmetry have not been previously investigated. Eighteen healthy males performed three unilateral drop jumps during which vertical stiffness and joint stiffness of the ankle and knee were calculated. Reactive strength index was also determined during the jumps using the ratio of flight time to ground contact time. ‘Moderate’ differences in vertical stiffness (t17 = 5.49; P < 0.001), ‘small’ differences in centre of mass displacement (t17 = -2.19; P = 0.043) and ‘trivial’ differences in ankle stiffness (t17 = 2.68; P = 0.016) were observed between stiff and compliant limbs. A model including ankle stiffness and reactive strength index symmetry angles explained 79% of the variance in vertical stiffness asymmetry (R2 = 0.79; P < 0.001). None of the symmetry angles were correlated to jump height or reactive strength index. Results suggest that asymmetries in ankle stiffness may play an important role in modulating vertical stiffness asymmetry in recreationally trained males

Deconstructing density: strategic dilemmas confronting the post-Apartheid city

Public authorities in many countries around the world are seeking to raise urban densities. Residential densification is particularly important in South Africa because of the colonial and apartheid legacy of sprawling, fragmented, racially divided cities. The paper examines the case for densifying central Cape Town and provides a framework to help deconstruct the concept and explore the policy challenges faced. It focuses on the bold aim to treble the area’s population within 10 years, and identifies issues where further consideration and public debate are required for how this can be achieved in a way that is desirable, affordable and fair. A key message is the need to understand both the composition of demand for central city living and the challenges involved in supplying suitable housing and amenities at higher densities. The level of social inequality in the city poses greater complications than elsewhere

Relationships between isometric force-time characteristics and dynamic performance

The purpose of this study was to explore the relationships between isometric mid-thigh pull (IMTP) force-time characteristics (peak force and time-specific force vales (100–250 ms)) and dynamic performance and compare dynamic performance between stronger and weaker athletes. Forty-three athletes from different sports (rowing, soccer, bicycle motocross, and hockey) performed three trials of the squat jump (SJ), countermovement jump (CMJ), and IMTP, and performed a one repetition maximum power clean (PC). Reactive strength index modified (RSImod) was also calculated from the CMJ. Statistically significant large correlations between IMTP force-time characteristics and PC (ρ = 0.569–0.674, p < 0.001), and moderate correlations between IMTP force-time characteristics (excluding force at 100 ms) and RSImod (ρ = 0.389–0.449, p = 0.013–0.050) were observed. Only force at 250 ms demonstrated a statistically significant moderate correlation with CMJ height (ρ = 0.346, p = 0.016) and no statistically significant associations were observed between IMTP force-time characteristics and SJ height. Stronger athletes (top 10) demonstrated statistically significantly greater CMJ heights, RSImods, and PCs (p ≤ 0.004, g = 1.32–1.89) compared to weaker (bottom 10) athletes, but no differences in SJ height were observed (p = 0.871, g = 0.06). These findings highlight that the ability to apply rapidly high levels of force in short time intervals is integral for PC, CMJ height, and reactive strength

Burkitt's lymphoma

Burkitt's lymphoma is a highly aggressive B-cell non-Hodgkin lymphoma and is the fastest growing human tumour. The disease is associated with Epstein-Barr virus and was one of the first tumours shown to have a chromosomal translocation that activates an oncogene (c-MYC). Burkitt's lymphoma is the most common childhood cancer in areas where malaria is holoendemic. The incidence is very high in immunosuppressed patients in non-endemic areas, especially when associated with HIV infection. Outcome with intensive chemotherapy has improved and is now excellent in children, but the prognosis is poor in elderly adults. The success of intensive treatment relies on good supportive care. The therapy offered in oncology units in low-income countries is not as aggressive as in centres in high-income countries and outcomes are less successful. Adjuvant monoclonal antibody therapy with rituximab shows promise for improved outcomes and reduced toxic effects in the future

Role of protein kinase C and μ-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons

In morphine tolerance a key question that remains to be answered is whether μ-opioid receptor (MOPr) desensitization contributes to morphine tolerance, and if so by what cellular mechanisms. Here we demonstrate that MOPr desensitization can be observed in single rat brainstem locus coeruleus (LC) neurons following either prolonged (> 4 h) exposure to morphine in vitro or following treatment of animals with morphine in vivo for 3 days. Analysis of receptor function by an operational model indicated that with either treatment morphine could induce a profound degree (70–80%) of loss of receptor function. Ongoing PKC activity in the MOPr-expressing neurons themselves, primarily by PKCα, was required to maintain morphine-induced MOPr desensitization, because exposure to PKC inhibitors for only the last 30–50 min of exposure to morphine reduced the MOPr desensitization that was induced both in vitro and in vivo. The presence of morphine was also required for maintenance of desensitization, as washout of morphine for > 2 h reversed MOPr desensitization. MOPr desensitization was homologous, as there was no change in α2-adrenoceptor or ORL1 receptor function. These results demonstrate that prolonged morphine treatment induces extensive homologous desensitization of MOPrs in mature neurons, that this desensitization has a significant PKC-dependent component and that this desensitization underlies the maintenance of morphine tolerance