The Laplace transform of the derivative of a function with finite jumps

Laplace transform of derivative of function with finite jump

Transfer matrix approach to layered systems with axial symmetry

The stress and displacement distribution in a layered medium is found by means of transfer matrices. The surface loading exhibits axial symmetry, and each layer is of infinite extent in the horizontal direction, of constant depth, and is considered to be linearly elastic, homogeneous, and isotropic. The method developed has the built-in advantage of enforcing interface continuity conditions automatically. Its application to layered composites shows the flexibility with which it predicts the local as well as the global response of the medium

Analisis Strategi Promosi Kesehatan di Puskesmas Bambalamotu dalam Pembinaan Masyarakat Suku Daa di Desa Kasoloang Kab.mamuju Utara

The This research is qualitative one that aimed to analyse strategy of health promotion through advocacy held by Center of The Society Health Bambalamotu in social construction of Tribe Daa in Wulai, North Mamuju. The selected informan was field worker of Center of The Society Health, leader of Center of The Society Health, cadre of countryside and society health by getting information through in depth interview, observation and FGD. The result of research showed that, for advocacy with Center of The Society Health through Inwrought Service Post, Circling Countryside Post, Ministrant of Centre of Health Society. Social support that was preparation to become cadre of health and society enablement was done by cadre of Inwrought Service Post in the form of counseling from government or social enablement institute and missioner (church). Suggested to the society ministrant in Clean and Healthy Life Style and other partnership, Social Enablement Institute and other society.Key Word : Health Promotion, Social Education, Tribe Da

Sikap Orang Tua terhadap Anak yang Tidak Melanjutkan Pendidikan Kejenjang yang Lebih Tinggi di Desa Bedeng Sikuran Kecamatan Inuman Kabupaten Kuantan Singingi

Abstrack: The problem in this research is: What is the attitude of parents of children who do not continue their education to a higher level. This study aims: To determine the attitude of parents of children who do not continue their education to a higher level. This research is deskrpitif with a quantitative approach, this method aims to provide a systematic overview of the state of the ongoing research on the object of the attitude of parents of children who do not melanjuttkan education to a higher level. Where the research is in the village of the District Inuman Bedeng Sikuran. The population in this study were parents in the village of the District Sikuran Bedeng Inuman, which amounted to 110 people, while a sample of 52 parents. The results showed that: Attitudes Parents of children who do not continue education to a higher level classified as Good. It is proved from the results of recapitulation of data, namely: 1.Komponen Cognitive respondents agreed amounted to 44.15%. 2. Affective component respondents saying Agree at 48.67% 3. Component Conative respondents agreed amounted to 45.05%

Nonlinear Relaxation Dynamics in Elastic Networks and Design Principles of Molecular Machines

Analyzing nonlinear conformational relaxation dynamics in elastic networks corresponding to two classical motor proteins, we find that they respond by well-defined internal mechanical motions to various initial deformations and that these motions are robust against external perturbations. We show that this behavior is not characteristic for random elastic networks. However, special network architectures with such properties can be designed by evolutionary optimization methods. Using them, an example of an artificial elastic network, operating as a cyclic machine powered by ligand binding, is constructed.Comment: 12 pages, 9 figure

Nipple Sparing Mastectomy Techniques: A Literature Review and an Inframammary Technique

Nipple sparing mastectomy (NSM) has quickly become an accepted technique for patients with selected cancers and for risk reducing surgery. Much of its surgical acceptance over the last decade has been based on the low risk of nipple areolar complex (NAC) occurrence in breast cancer patients. Improved patient satisfaction due to improved cosmetic outcomes with reconstruction have also driven its popularity. We reviewed current English journals to determine the NSM techniques which achieve the lowest complications, best outcomes, and best patient satisfaction. We researched studies showing reductions in complications with improved surgical techniques and patient selection which have been implicated in improved results. In the studies reviewed, incision placement, away from the nipple, resulted in the lowest rates of ischemic nipple complications and the best cosmetic outcomes. The effect of other factors such as surgeon experience and thickness of skin flap development were more difficult to prove. Leaving a 2-3 mm rim of tissue around the nipple bundle was shown to help preserve the nipple vascularity. Lower complication rates with improved outcomes and patient satisfaction were reported in the literature in patients with B or smaller cup sizes, non-smokers, and patients with lower body mass index (BMI). Incision placement, away from the nipple, with preservation of a 2-3 mm rim of tissue around the nipple bundle along with careful patient selection were the most significant variables reviewed which helped to lower complications rates of NSM. Coordinated surgical planning with the breast and plastic surgeons to determine the best surgical approach for each individual patient is necessary to obtain the best results. Although short-term oncologic follow-up seems to be acceptable, longer follow-up will still be needed to define the best breast cancer surgical candidates for the nipple sparing approach

Recent advances in location analysis

The final publication is available at Elsevier via http://dx.doi.org/10.1016/j.cor.2015.04.013 © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/Introduction to a special issue of Computers & Operations Research dedicated to recent advances in location analysis

On the single-assignment p-hub center problem

We study the computational aspects of the single-assignment p-hub center problem on the basis of a basic model and a new model. The new model's performance is substantially better in CPU time than different linearizations of the basic model. We also prove the NP-Hardness of the problem

The Use of Experimental Structures to Model Protein Dynamics

The number of solved protein structures submitted in the Protein Data Bank (PDB) has increased dramatically in recent years. For some specific proteins, this number is very high—for example, there are over 550 solved structures for HIV-1 protease, one protein that is essential for the life cycle of human immunodeficiency virus (HIV) which causes acquired immunodeficiency syndrome (AIDS) in humans. The large number of structures for the same protein and its variants include a sample of different conformational states of the protein. A rich set of structures solved experimentally for the same protein has information buried within the dataset that can explain the functional dynamics and structural mechanism of the protein. To extract the dynamics information and functional mechanism from the experimental structures, this chapter focuses on two methods—Principal Component Analysis (PCA) and Elastic Network Models (ENM). PCA is a widely used statistical dimensionality reduction technique to classify and visualize high-dimensional data. On the other hand, ENMs are well-established simple biophysical method for modeling the functionally important global motions of proteins. This chapter covers the basics of these two. Moreover, an improved ENM version that utilizes the variations found within a given set of structures for a protein is described. As a practical example, we have extracted the functional dynamics and mechanism of HIV-1 protease dimeric structure by using a set of 329 PDB structures of this protein. We have described, step by step, how to select a set of protein structures, how to extract the needed information from the PDB files for PCA, how to extract the dynamics information using PCA, how to calculate ENM modes, how to measure the congruency between the dynamics computed from the principal components (PCs) and the ENM modes, and how to compute entropies using the PCs. We provide the computer programs or references to software tools to accomplish each step and show how to use these programs and tools. We also include computer programs to generate movies based on PCs and ENM modes and describe how to visualize them