La perspectiva interdisciplinaria en la enseñanza de las Ciencias Naturales para la formación docente

En el trabajo proponemos la necesidad de un marco conceptual interdisciplinario para el abordaje de la formación docente de grado. Las ciencias naturales permiten este enfoque. Articulando campos de acción con otras disciplinas y generando espacios de reflexión en encuentros de tipo taller, a partir de las vivencias prácticas de contenidos trabajados en clase y favoreciendo el aprender haciendo, intentamos promover la adquisición y el afianzamiento de contenidos y competencias. Desarrollamos este marco conceptual y ejemplificamos con una experiencia realizada desde las ciencias naturales en una institución de formación docente de la zona.Trabajos del área Ciencias NaturalesFacultad de Ciencias Médica

The impact of the Great Recession on mental health and its inequalities: the case of a Southern European region, 1997–2013

Background: Numerous studies have shown that macroeconomic changes have a great influence on health, prompting different concerns in recent literature about the effects of the current recession. The objetive of the study was to assess the changes in the mental health of the working-age population in the Basque Country (Spain) and its social inequalities following the onset of the 2008 recession, with special focus on the role of unemployment. Methods: Repeated cross-sectional study on the population aged 16-64, using four Basque Health Surveys (1997-2013). Age-adjusted prevalences of poor mental health and incremental prevalence ratios (working status and social class adjusted) between years were calculated. Absolute/relative measures of social inequalities were also calculated. Results: From 2008, there was a clear deterioration in the mental health, especially among men. Neither changes in employment status nor social class accounted for these changes. In men, the deterioration affected all working status categories, except the retired but significant changes occurred only among the employed. In women, poor mental health significantly increased among the unemployed. Students were also especially affected. Relative inequalities increased only in men. Conclusions: The Great Recession is being accompanied by adverse effects on mental health, which cannot be fully explained by the increase of unemployment. Public healtThis work was partially supported by the Ministry of Economy and Competitiveness (State Programme for Promotion of Scientific and Technical Research Challenges (CSO2013-44886-R))

Estudio exploratorio de la toxoplasmosis y leptospirosis en pequeños rumiantes y animales de granja en el Departamento La Capital, San Luis.

La Toxoplasmosis y la Leptospirosis como enfermedades zoonóticas afectan a animales y seres humanos, por lo que el conocimiento de factores causales y consecuencias de su existencia en una localidad o región implica el trabajo interdisciplinario. La toxoplasmosis es una enfermedad producida por un parásito protozoario unicelular eucariota, llamado Toxoplasma gondii, que puede afectar a todos los animales de sangre caliente inclusive al ser humano y es de distribución mundial

Humoral and cellular immune response and transplacental transmission in cows experimentally infected with Neospora caninum NC-6 Argentina strain

La infección por Neospora caninum es una importante causa de aborto en los bovinos. El objetivo de este estudio fue evaluar la respuesta inmune humoral y celular en bovinos y la posibilidad de transmisión transplacentaria durante una infección experimental con la cepa de N. caninum NC-6 Argentina. Se inocularon vacas preñadas de 65 días de gestación seropositivas (SP) y seronegativas (SN) a N. caninum por vía intravenosa con 108 taquizoítos de la cepa NC-6 o con PBS como control negativo.Facultad de Ciencias VeterinariasInstituto Nacional de Tecnología Agropecuari

Cryptic invasion drives phenotypic changes in central European threespine stickleback

Cryptic invasions are commonly associated with genetic changes of the native species or genetic lineage that the invaders replace. Phenotypic shifts resulting from cryptic invasions are less commonly reported given the relative paucity of historical specimens that document such phenotypic changes. Here, I study such a case in two populations of threespine stickleback from central Europe, comparing contemporary patterns of gene flow with phenotypic changes between historical and contemporary population samples. I find gene flow from an invasive lineage to be associated with significant phenotypic changes, where the degree of phenotypic change corresponds with the level of gene flow that a population receives. These findings underline the utility of combining genetic approaches with phenotypic data to estimate the impact of gene flow in systems where anthropogenic alterations have removed former geographic barriers promoting cryptic invasions

Large-scale association analyses identify host factors influencing human gut microbiome composition

To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data from 18,340 individuals (24 cohorts). Microbial composition showed high variability across cohorts: only 9 of 410 genera were detected in more than 95% of samples. A genome-wide association study of host genetic variation regarding microbial taxa identified 31 loci affecting the microbiome at a genome-wide significant (P < 5 x 10(-8)) threshold. One locus, the lactase (LCT) gene locus, reached study-wide significance (genome-wide association study signal: P = 1.28 x 10(-20)), and it showed an age-dependent association with Bifidobacterium abundance. Other associations were suggestive (1.95 x 10(-10) < P < 5 x 10(-8)) but enriched for taxa showing high heritability and for genes expressed in the intestine and brain. A phenome-wide association study and Mendelian randomization identified enrichment of microbiome trait loci in the metabolic, nutrition and environment domains and suggested the microbiome might have causal effects in ulcerative colitis and rheumatoid arthritis