How inter-firm networks influence the development of agglomerations

Non-market interactions are increasingly regarded as key explanations for spatial concentration. Consistently, both innovation and local knowledge spillovers play a central role in recent theories of agglomeration. According to these theories, exchange of localised knowledge gives firms an innovative advantage which results in better economic performance. However, it has turned out to be difficult to open the black box of economies of scale using empirical tests.\ud Since interactions get considerable attention in recent agglomeration theory, social network methods and theory are promising approaches to research spatial agglomerations. Even more so because simultaneously, there is an increasing emphasis on interfirm ties in the network field.\ud The goal of our research is to explore how interfirm networks influence the development of agglomerations. Firstly we provide a review on network and innovation literature in the field of spatial clusters. Secondly, we discuss measurement issues related to networks and innovation and ways to overcome them. Finally, we present preliminary results of our network study among high tech firms in the Dutch region of Twente

Long-term wine consumption is related to cardiovascular mortality and life expectancy independently of moderate alcohol intake: the Zutphen Study

Background: Light to moderate alcohol intake lowers the risk of cardiovascular mortality, but whether this protective effect can be attributed to a specific type of beverage remains unclear. Moreover, little is known about the effects of long-term alcohol intake on life expectancy. Methods: The impact of long-term alcohol intake and types of alcoholic beverages consumed on cardiovascular mortality and life expectancy at age 50 was investigated in the Zutphen Study, a cohort of 1373 men born between 1900 and 1920 and examined repeatedly between 1960 and 2000. Hazard ratios (HRs) for total alcohol intake and alcohol from wine, beer and spirits were obtained from time-dependent Cox regression models. Life expectancy at age 50 was calculated from areas under survival curves. Results: Long-term light alcohol intake, that is =20 g per day, compared with no alcohol, was strongly and inversely associated with cerebrovascular (HR 0.43, 95% CI 0.26 to 0.70), total cardiovascular (HR 0.70, 95% CI 0.55 to 0.89) and all-cause mortality (HR 0.75, 95% CI 0.63 to 0.91). Independent of total alcohol intake, long-term wine consumption of, on average, less than half a glass per day was strongly and inversely associated with coronary heart disease (HR 0.61, 95% CI 0.41 to 0.89), total cardiovascular (HR 0.68, 95% CI 0.53 to 0.86) and all-cause mortality (HR 0.73, 95% CI 0.62 to 0.87). These results could not be explained by differences in socioeconomic status. Life expectancy was about 5 years longer in men who consumed wine compared with those who did not use alcoholic beverages. Conclusion: Long-term light alcohol intake lowered cardiovascular and all-cause mortality risk and increased life expectancy. Light wine consumption was associated with 5 years longer life expectancy; however, more studies are needed to verify this resul

Standardized exercise tests in horses : current situation and future perspectives

The purpose of this literature review is to clarify how exercise capacity can be measured in horses and which standardized exercise tests (SETs) exist. In this review, the measurement of the exercise capacity of horses is discussed and the standardized exercise tests (SET) are described. Two main types of SETs are used. Laboratory or treadmill tests are easy to standardize and provide more options to use all kinds of measuring devices, since the horse stays on the treadmill. On the other hand, field tests are conducted under the natural conditions associated with the specific sports discipline, and are easier to implement in the training schedule. However, field tests encompass interfering variables, such as weather conditions, ground surface conditions and the rider or jockey. Several variables are measured in order to calculate the fitness level which may be expressed by different parameters, such as V200 (speed at a heart rate of 200 beats per minute), V1a4 (speed at a blood lactic acid level of 4 mmol/L) and VO2max (maximum oxygen uptake)

On the origin of intermediate effects in clinical case recall

In two experiments, the effects of level of medical expertise and study time on free recall of a clinical case were assessed. In Experiment 1, a nonmonotonic relationship between level of expertise and recall was found: Subjects of intermediate levels of expertise remembered more information from the case than both experts and novices. This "intermediate effect" disappeared, however, when study time was restricted. Analysis of post hoc acquired protocols of pathophysiological knowledge active during case processing suggested that this phenomenon could be attributed to the nature of the pathophysiological knowledge mobilized to comprehend the case. In Experiment 2, this assumption was directly tested by priming relevant pathophysiological knowledge for either a short or a longer period, before enabling subjects to study the case briefly. Free-recall data confirmed and extended the results of Experiment 1. Again, an intermediate effect was found; this time, however, it was generated experimentally. The findings were interpreted in terms of qualitative differences in the nature of the knowledge structures underlying performance between novices, advanced students, and medical experts: Experts use knowledge in an encapsulated mode while comprehending a case, whereas students use elaborated knowledge

The role of education in selection and allocation on the labour market; An empirical study in the medical field

In this study, we explore the role of education in explaining the labour market outcomes for graduates in medicine. More specifically, we focus on the question: To what extent are labour market outcomes of physicians explained by the skills acquired in education, as argued in the theory of Human Capital, by competences already present at the start of education, as suggested by the Screening theory literature, or by having attained the medical degree as such, as suggested by the literature on Credentialism? The study uses separate measurements of competence at the start and at the end of academic education. These are grade point averages (GPA’s) of secondary school, available at the start of the first year of study, versus the final (medical) Skills test at the end of the study. Moreover, we use a direct measurement of competence development during medical education in the form of Progress Test results; the first Progress Test result in the first year, versus the final Progress Test result in the fourth year of study. This enables us to disentangle the effects of the three suggested mechanisms. The results suggest that after graduation the human capital factors available do not explain subsequent differences in labour market outcomes. The data therefore suggest evidence for Credentialism. However, selection processes during education and in the response to the labour market survey, take place on human capital acquired before and during education.labour market entry and occupational careers;

Competence indicators in academic education and early labour market success of graduates in health sciences

In this study, the effects of several educational and non-educational indicators of (aspects of) competence on short-term labour market outcomes for university graduates are estimated. The research question we address is: To what extent do indications of specific and generic competence during the educational program predict labour market outcomes? Labour market outcomes in this study pertain to employment chances and quality of the job (having a job, academic level, matching occupational domain and wages). We use data on specific and generic aspects of competence, all of which were assessed during the academic study course, i.e. test scores on the attainment of domain specific knowledge, scores on group functioning, and the Masters’ thesis result. In addition, some other indicators of human capital acquired outside education are used, i.e. relevant work experience and managerial experience. The results indicate a rather differentiated pattern for the value of specific and generic competence acquired during education for the labour market.labour market entry and occupational careers;

Do prior attitudes influence epistemic cognition while reading conflicting information?

Van Strien, J. L. H., Brand-Gruwel, S., & Boshuizen, H. P. A. (2012, August). Do prior attitudes influence epistemic cognition while reading conflicting information? Poster presented at the biannual meeting of the EARLI Special Interest Group Comprehension of Text and Graphics, Grenoble, France.Students spontaneously engage in epistemic cognition when reading conflicting scientific information. This study examines how this epistemic cognition is related to students’ actual beliefs. In addition, the interplay of students’ epistemic beliefs and prior attitudes when encountering conflicting and partly attitude-inconsistent information on a controversial socio-scientific is studied using think-aloud methods

Information- problem solving: A review of problems students encounter and instructional solutions

Walraven, A., Brand-Gruwel, S., & Boshuizen, H.P.A. (2008). Information- problem solving: A review of problems students encounter and instructional solutions. Computers in Human Behavior, 24 (3), 623-648.Searching and processing information is a complex cognitive process that requires students to identify information needs, locate corresponding information sources, extract and organize relevant information from each source, and synthesize information from a variety of sources. This process is called information-problem solving (IPS). IPS can be characterized as a complex cognitive skill, which may need direct instruction to reach high levels of performance. However, IPS has been given little attention in schools, and instruction in this skill is rarely embedded in curricula. And yet, by giving students assignments in which students have to solve an information-based problem, teachers assume that their pupils have developed this skill naturally. A literature study was done to determine what kinds of problems students experience when solving information problems using the WWW for searching information, and what kind of instructional support can help to solve these problems. Results show that children, teenagers and adults have trouble with specifying search terms, judging search results and judging source and information. Regulating the search process is also problematic. Instruction designed specifically for IPS using the WWW for searching information is rare but indeed addresses the problematic skills. However, there are differences between various methods and it is unclear which method is most effective for specific age groups

A method for sensitivity analysis to assess the effects of measurement error in multiple exposure variables using external validation data

Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a disease. The association can be distorted further by mismeasured confounders, leading to invalid results and conclusions. It is, however, difficult to adjust for the bias in the association when there is no internal validation data