906 research outputs found
Cosmology with Weak Lensing Surveys
Weak gravitational lensing surveys measure the distortion of the image of
distant sources due to the deflections of light rays by the fluctuations of the
gravitational potential along the line of sight. Since they probe the
non-linear matter power spectrum itself at medium redshift such surveys are
complimentary to both galaxy surveys (which follow stellar light) and cosmic
microwave background observations (which probe the linear regime at high
redshift). Ongoing CMB experiments such as WMAP and the future Planck satellite
mission will measure the standard cosmological parameters with unprecedented
accuracy. The focus of attention will then shift to understanding the nature of
dark matter and vacuum energy: several recent studies suggest that lensing is
the best method for constraining the dark energy equation of state. During the
next 5 year period ongoing and future weak lensing surveys such as the Joint
Dark Energy Mission (JDEM, e.g. SNAP) or the Large-aperture Synoptic Survey
Telescope (LSST) will play a major role in advancing our understanding of the
universe in this direction. In this review article we describe various aspects
of weak lensing surveys and how they can help us in understanding our universe.Comment: 15 pages, review article to appear in 2005 Triennial Issue of Phil.
Trans.
Photon Spectrum Produced by the Late Decay of a Cosmic Neutrino Background
We obtain the photon spectrum induced by a cosmic background of unstable
neutrinos. We study the spectrum in a variety of cosmological scenarios and
also we allow for the neutrinos having a momentum distribution (only a critical
matter dominated universe and neutrinos at rest have been considered until
now). Our results can be helpful when extracting bounds on neutrino electric
and magnetic moments from cosmic photon background observations.Comment: RevTex, 14 pages, 3 figures; minor changes, references added. To
appear in Phys. Rev.
Strong Gravitational Lensing and Dark Energy Complementarity
In the search for the nature of dark energy most cosmological probes measure
simple functions of the expansion rate. While powerful, these all involve
roughly the same dependence on the dark energy equation of state parameters,
with anticorrelation between its present value w_0 and time variation w_a.
Quantities that have instead positive correlation and so a sensitivity
direction largely orthogonal to, e.g., distance probes offer the hope of
achieving tight constraints through complementarity. Such quantities are found
in strong gravitational lensing observations of image separations and time
delays. While degeneracy between cosmological parameters prevents full
complementarity, strong lensing measurements to 1% accuracy can improve
equation of state characterization by 15-50%. Next generation surveys should
provide data on roughly 10^5 lens systems, though systematic errors will remain
challenging.Comment: 7 pages, 5 figure
Dielectronic Recombination in He+ Ions
This research was sponsored by the National Science Foundation Grant NSF PHY-931478
M2ORM2: A Model for the Transparent Management of Relationally Persistent Objects
Object-oriented application development often involves
storing application objects in a relational database.
Sometimes it is desirable to develop
the persistent classes and the relational database
in an independent way, and
to use an object persistent manager to connect them in a suitable way.
This paper introduces {M2ORM2,
a model for describing meet-in-the-middle mappings
between object schemas and relational schemas,
to support the transparent management of object persistence
by means of relational databases
Notes on bordered Floer homology
This is a survey of bordered Heegaard Floer homology, an extension of the
Heegaard Floer invariant HF-hat to 3-manifolds with boundary. Emphasis is
placed on how bordered Heegaard Floer homology can be used for computations.Comment: 73 pages, 29 figures. Based on lectures at the Contact and Symplectic
Topology Summer School in Budapest, July 2012. v2: Fixed many small typo
Chitayat syndrome: hyperphalangism, characteristic facies, hallux valgus and bronchomalacia results from a recurrent c.266A>G p.(Tyr89Cys) variant in the ERF gene.
BACKGROUND: In 1993, Chitayat et al., reported a newborn with hyperphalangism, facial anomalies, and bronchomalacia. We identified three additional families with similar findings. Features include bilateral accessory phalanx resulting in shortened index fingers; hallux valgus; distinctive face; respiratory compromise. OBJECTIVES: To identify the genetic aetiology of Chitayat syndrome and identify a unifying cause for this specific form of hyperphalangism. METHODS: Through ongoing collaboration, we had collected patients with strikingly-similar phenotype. Trio-based exome sequencing was first performed in Patient 2 through Deciphering Developmental Disorders study. Proband-only exome sequencing had previously been independently performed in Patient 4. Following identification of a candidate gene variant in Patient 2, the same variant was subsequently confirmed from exome data in Patient 4. Sanger sequencing was used to validate this variant in Patients 1, 3; confirm paternal inheritance in Patient 5. RESULTS: A recurrent, novel variant NM_006494.2:c.266A>G p.(Tyr89Cys) in ERF was identified in five affected individuals: de novo (patient 1, 2 and 3) and inherited from an affected father (patient 4 and 5). p.Tyr89Cys is an aromatic polar neutral to polar neutral amino acid substitution, at a highly conserved position and lies within the functionally important ETS-domain of the protein. The recurrent ERF c.266A>C p.(Tyr89Cys) variant causes Chitayat syndrome. DISCUSSION: ERF variants have previously been associated with complex craniosynostosis. In contrast, none of the patients with the c.266A>G p.(Tyr89Cys) variant have craniosynostosis. CONCLUSIONS: We report the molecular aetiology of Chitayat syndrome and discuss potential mechanisms for this distinctive phenotype associated with the p.Tyr89Cys substitution in ERF
Supersymmetric Gauge Theories, Intersecting Branes and Free Fermions
We show that various holomorphic quantities in supersymmetric gauge theories
can be conveniently computed by configurations of D4-branes and D6-branes.
These D-branes intersect along a Riemann surface that is described by a
holomorphic curve in a complex surface. The resulting I-brane carries
two-dimensional chiral fermions on its world-volume. This system can be mapped
directly to the topological string on a large class of non-compact Calabi-Yau
manifolds. Inclusion of the string coupling constant corresponds to turning on
a constant B-field on the complex surface, which makes this space
non-commutative. Including all string loop corrections the free fermion theory
is elegantly formulated in terms of holonomic D-modules that replace the
classical holomorphic curve in the quantum case.Comment: 67 pages, 6 figure
Treatment effect of switching from intravenous to subcutaneous C1-inhibitor for prevention of hereditary angioedema Attacks : COMPACT subgroup findings
The decay pi0 to gamma gamma to next to leading order in Chiral Perturbation Theory
The two photon decay width of the neutral pion is analyzed within the
combined framework of Chiral Perturbation Theory and the 1/Nc expansion up to
order p^6 and p^4 times 1/Nc in the decay amplitude. The eta' is explicitly
included in the analysis. It is found that the decay width is enhanced by about
4.5% due to the isospin-breaking induced mixing of the pure U(3) states. This
effect, which is of leading order in the low energy expansion, is shown to
persist nearly unchanged at next to leading order. The chief prediction for the
width with its estimated uncertainty is 8.10+-0.08 eV. This prediction at the
1% level makes the upcomming precision measurement of the decay width even more
urgent.
Observations on the eta and eta' can also be made, especially about their
mixing, which is shown to be significantly affected by next to leading order
corrections.Comment: 21 pages, two figure
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