385 research outputs found
Approaching the Gamow Window with Stored Ions : Direct Measurement of Xe 124 (p,γ) in the ESR Storage Ring
© 2019 American Physical Society. All rights reserved.We report the first measurement of low-energy proton-capture cross sections of Xe124 in a heavy-ion storage ring. Xe12454+ ions of five different beam energies between 5.5 and 8 AMeV were stored to collide with a windowless hydrogen target. The Cs125 reaction products were directly detected. The interaction energies are located on the high energy tail of the Gamow window for hot, explosive scenarios such as supernovae and x-ray binaries. The results serve as an important test of predicted astrophysical reaction rates in this mass range. Good agreement in the prediction of the astrophysically important proton width at low energy is found, with only a 30% difference between measurement and theory. Larger deviations are found above the neutron emission threshold, where also neutron and γ widths significantly impact the cross sections. The newly established experimental method is a very powerful tool to investigate nuclear reactions on rare ion beams at low center-of-mass energies.Peer reviewedFinal Published versio
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Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases.
PurposeTo describe examples of missed pathogenic variants on whole-exome sequencing (WES) and the importance of deep phenotyping for further diagnostic testing.MethodsGuided by phenotypic information, three children with negative WES underwent targeted single-gene testing.ResultsIndividual 1 had a clinical diagnosis consistent with infantile systemic hyalinosis, although WES and a next-generation sequencing (NGS)-based ANTXR2 test were negative. Sanger sequencing of ANTXR2 revealed a homozygous single base pair insertion, previously missed by the WES variant caller software. Individual 2 had neurodevelopmental regression and cerebellar atrophy, with no diagnosis on WES. New clinical findings prompted Sanger sequencing and copy number testing of PLA2G6. A novel homozygous deletion of the noncoding exon 1 (not included in the WES capture kit) was detected, with extension into the promoter, confirming the clinical suspicion of infantile neuroaxonal dystrophy. Individual 3 had progressive ataxia, spasticity, and magnetic resonance image changes of vanishing white matter leukoencephalopathy. An NGS leukodystrophy gene panel and WES showed a heterozygous pathogenic variant in EIF2B5; no deletions/duplications were detected. Sanger sequencing of EIF2B5 showed a frameshift indel, probably missed owing to failure of alignment.ConclusionThese cases illustrate potential pitfalls of WES/NGS testing and the importance of phenotype-guided molecular testing in yielding diagnoses
High-resolution measurement of the time-modulated orbital electron capture and of the decay of hydrogen-like Pm ions
The periodic time modulations, found recently in the two-body orbital
electron-capture (EC) decay of both, hydrogen-like Pr and
Pm ions, with periods near to 7s and amplitudes of about 20%,
were re-investigated for the case of Pm by using a 245 MHz
resonator cavity with a much improved sensitivity and time resolution. We
observed that the exponential EC decay is modulated with a period s, in accordance with a modulation period s as obtained
from simultaneous observations with a capacitive pick-up, employed also in the
previous experiments. The modulation amplitudes amount to and
for the 245 MHz resonator and the capacitive pick-up,
respectively. These new results corroborate for both detectors {\it exactly}
our previous findings of modulation periods near to 7s, though with {\it
distinctly smaller} amplitudes. Also the three-body decays have been
analyzed. For a supposed modulation period near to 7s we found an amplitude , compatible with and in agreement with the preliminary
result of our previous experiment. These observations could
point at weak interaction as origin of the observed 7s-modulation of the EC
decay. Furthermore, the data suggest that interference terms occur in the
two-body EC decay, although the neutrinos are not directly observed.Comment: In memoriam of Prof. Paul Kienle, 9 pages, 1 table, 5 figures Phys.
Lett. B (2013) onlin
Bound -state β- -decay of bare 205 Tl 81+
Beta decay into bound electron states of the daughter atom accompanied by the emission of a monochromatic antineutrino, has been predicted by Daudel et al.[1]. However, a noteworthy probability of βb- decay exists only for highly-charged ions, which makes its observation rather difficult
Indirect measurements of neutron-induced reaction cross sections at storage rings
Neutron-induced reaction cross sections of unstable nuclei are essential for understanding the synthesis of heavy elements in stars. However, their measurement is very difficult due to the radioactivity of the targets involved. We propose to circumvent this problem by using for the first time the surrogate reaction method in inverse kinematics at heavy-ion storage rings. In this contribution, we describe the developments we have done to perform surrogate-reaction studies at the storage rings of GSI/FAIR. In particular, we present the first results of the proof of principle experiment, which we conducted recently at the Experimental Storage Ring (ESR)
Relativistic quantum dynamics in strong fields: Photon emission from heavy, few-electron ions
Recent progress in the study of the photon emission from highly-charged heavy
ions is reviewed. These investigations show that high- ions provide a unique
tool for improving the understanding of the electron-electron and
electron-photon interaction in the presence of strong fields. Apart from the
bound-state transitions, which are accurately described in the framework of
Quantum Electrodynamics, much information has been obtained also from the
radiative capture of (quasi-) free electrons by high- ions. Many features in
the observed spectra hereby confirm the inherently relativistic behavior of
even the simplest compound quantum systems in Nature.Comment: Version 18/11/0
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