New methodology for assessing the probability of contaminating Mars

Methodology is proposed to assess the probability that the planet Mars will be contaminated by terrestrial microorganisms aboard a spacecraft. The present NASA methods are extended to permit utilization of detailed information on microbial characteristics, the lethality of release and transport mechanisms, and of other information about the Martian environment. Different types of microbial release are distinguished, and for each release mechanism a probability of growth is computed. Using this new methodology, an assessment was carried out for the 1975 Viking landings on Mars. The resulting probability of contamination for each Viking lander is 6 x 10 to the -6 power, and is amenable to revision as additional information becomes available

Assessment of the probability of contaminating Mars

New methodology is proposed to assess the probability that the planet Mars will by biologically contaminated by terrestrial microorganisms aboard a spacecraft. Present NASA methods are based on the Sagan-Coleman formula, which states that the probability of contamination is the product of the expected microbial release and a probability of growth. The proposed new methodology extends the Sagan-Coleman approach to permit utilization of detailed information on microbial characteristics, the lethality of release and transport mechanisms, and of other information about the Martian environment. Three different types of microbial release are distinguished in the model for assessing the probability of contamination. The number of viable microbes released by each mechanism depends on the bio-burden in various locations on the spacecraft and on whether the spacecraft landing is accomplished according to plan. For each of the three release mechanisms a probability of growth is computed, using a model for transport into an environment suited to microbial growth

Binaries with total eclipses in the LMC: potential targets for spectroscopy

35 Eclipsing binaries presenting unambiguous total eclipses were selected from a subsample of the list of Wyrzykowski et al. (2003). The photometric elements are given for the I curve in DiA photometry, as well as approximate Teff and masses of the components. The interest of these systems is stressed in view of future spectroscopic observations.Comment: 4 pages, 1 figure; poster presented at the conference "Close binaries in the 21st Century: new opportunities and challenges", Syros, 27-30 June 200

CNONa and 12C/13C in giants of 10 open clusters

Evolved low-mass stars of a wide range of metallicity bear signatures of a non-standard mixing event in their surface abundances of Li, C, and N, and in their 12C/13C ratio. A Na overabundance has also been reported in some giants of open clusters but remains controversial. The cause of the extra-mixing has been attributed to thermohaline convection that should take place after the RGB bump for low-mass stars and on the early-AGB for more massive objects. To track the occurrence of this process over a wide mass range, we derive in a homogeneous way the abundances of C, N, O, and Na, as well as the 12C/13C ratio in a sample of 31 giants of 10 open clusters with turn-off masses from 1.7 to 3.1 Msun. A group of first ascent red giants with M/Msun \leq 2.5 exhibits lower [N/C] ratios than those measured in clump giants of the same mass range, suggesting an additional increase in the [N/C] ratio after the first dredge-up. The sodium abundances corrected from NLTE are found to be about solar. [Na/Fe] shows a slight increase of 0.10 dex as a function of stellar mass in the 1.8 to 3.2 Msun range covered by our sample, in agreement with standard first dredge-up predictions. Our results do not support previous claims of sodium overabundances as high as +0.60 dex. An anti-correlation between 12C/13C and turn-off mass is identified and interpreted as being caused by a post-bump thermohaline mixing. Moreover, we find low 12C/13C ratios in a few intermediate-mass early-AGB stars, confirming that an extra-mixing process also operates in stars that do not experienced the RGB bump. In this case, the extra-mixing possibly acts on the early-AGB, in agreement with theoretical expectations for thermohaline mixing. [abridged]Comment: A&A accepted, revised versio

Assessing somatization in urologic chronic pelvic pain syndrome

BACKGROUND: This study examined the prevalence of somatization disorder in Urological Chronic Pelvic Pain Syndrome (UCPPS) and the utility of two self-report symptom screening tools for assessment of somatization in patients with UCPPS. METHODS: The study sample included 65 patients with UCPPS who enrolled in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Study at Washington University. Patients completed the PolySymptomatic PolySyndromic Questionnaire (PSPS-Q) (n = 64) and the Patient Health Questionnaire-15 Somatic Symptom Severity Scale (PHQ-15) (n = 50). Review of patient medical records found that only 47% (n = 30) contained sufficient documentation to assess Perley-Guze criteria for somatization disorder. RESULTS: Few (only 6.5%) of the UCPPS sample met Perley-Guze criteria for definite somatization disorder. Perley-Guze somatization disorder was predicted by definite PSPS-Q somatization with at least 75% sensitivity and specificity. Perley-Guze somatization disorder was predicted by severe (\u3e 15) PHQ-15 threshold that had \u3e 90% sensitivity and specificity but was met by only 16% of patients. The moderate (\u3e 10) PHQ-15 threshold had higher sensitivity (100%) but lower specificity (52%) and was met by 52% of the sample. CONCLUSIONS: The PHQ-15 is brief, but it measures symptoms constituting only one dimension of somatization. The PSPS-Q uniquely captures two conceptual dimensions inherent in the definition of somatization disorder, both number of symptoms and symptom distribution across multiple organ systems, with relevance for UCPPS as a syndrome that is not just a collection of urological symptoms but a broader syndrome with symptoms extending beyond the urological system

Connection and coherence between and among European instruments in the private international law of obligations

This article considers points of connection and coherence between and among the Rome I Regulation, the Rome II Regulation, and Regulation 1215, and relevant predecessor instruments. The degree of consistency in aim, design and detail of conflict of laws rules is examined, vertically (between/among consecutive instruments) and horizontally (across cognate instruments). Symbiosis between instruments is explored, as is the interrelationship between choice of court and choice of law. Disadvantaged parties, and the cohesiveness of their treatment under the Regulations, receive particular attention

Tactile reasoning and adaptive architecture for intelligence sense-making

Visual analytics is the science of analytical facilitated by interactive visual interfaces [1]. Visual analytics combines automated analysis techniques with interactive visualizations to facilitate reasoning and making sense of large and complex data sets [2]. A key component of visual analytics is information visualisation, which is the communication of abstract data through visual representations that simplify, aggregate and reveal important relationships [3]. However, information visualisation is just one part of the equation that is visual analytics. The ability to manipulate the data directly and to query and initiate analytic processes through that manipulation with the resulting information is the other major component of visual analytics [1]. Together, interaction, visualisation, and analytics, combine to create powerful tools for supporting the analysis and reasoning with large, mix‐format, multi‐source data sets. We are interested in the application of tactile reasoning to visual analytics. We define tactile reasoning as an interaction technique that supports the analytical reasoning process by the direct manipulation of information objects in a graphical user interface (GUI). In a study by Maglio et al [4] they found that participants using scrabble pieces (individual alphabets on tiles) generated more words when they were allowed to manipulate the scrabble pieces than when they are not allowed to interact with the pieces. The act of tactile manipulation of the scrabble pieces, i.e. the ability to rearrange them, allowed the participants to form words that they could not form without interaction. Tactile reasoning, we therefore hypothesise, enables individuals to see patterns in visually presented data sets they might otherwise not see through the manipulation, rearrangement and other interaction with the information objects. In this paper we describe the concept of tactile reasoning in the context of visual analytics, and the adaptive architecture needed to support it during real‐time manipulation. We conduct our investigation through a lab prototype – INVISQUE – Interactive Visual Search and Query Environment [4,5]. INVISQUE provides an information visualisation interface coupled with a “reasoning workspace” that facilitates tactile reasoning. INVISQUE was funded by JISC to provide an alternative interface to improve information search and retrieval and sense‐making in electronic library resource discovery systems such as the Emerald and ISI electronic journal databases. We have developed an adaptive architecture which underlies INVISQUE and supports the sense‐making by providing the system with the capability to rapidly adapt to changing circumstances

Limited access orders in the developing world :a new approach to the problems of development

The upper-income, advanced industrial countries of the world today all have market economies with open competition, competitive multi-party democratic political systems, and a secure government monopoly over violence. Such open access orders, however, are not the only norm and equilibrium type of society. The middle and low-income developing countries today, like all countries before about 1800, can be understood as limited access orders that maintain their equilibrium in a fundamentally different way. In limited access orders, the state does not have a secure monopoly on violence, and society organizes itself to control violence among the elite factions. A common feature of limited access orders is that political elites divide up control of the economy, each getting some share of the rents. Since outbreaks of violence reduce the rents, the elite factions have incentives to be peaceable most of the time. Adequate stability of the rents and thus of the social order requires limiting access and competition-hence a social order with a fundamentally different logic than the open access order. This paper lays out such a framework and explores some of its implications for the problems of development today.Corporate Law,Labor Policies,Public Sector Corruption&Anticorruption Measures,E-Business,Disability