Secure Elliptic Curve Digital Signature Algorithm for Internet of Things

In the previous couple of years, the internet of things (IoT) is gaining additional and a lot of attention each within the academia and in the industrial worlds. A wide accepted notion of the internet of things (IoT) is stated the chance of militarization everyday objects with adequate technology to permit them to speak with alternative objects, identify themselves, or perhaps participate to distribute computing. These things are customarily stated as SO2019;s (Smart Object), might be drawn as actual relics augmented with computing, communication, actuations and storing functionalities. Their importance resides within the capabilities they need to create physical environments 201C;smart201D; therefore as to offer novel cyber physical service to individuals. smart Objects, that are vital elements of the IOT, are everyday objects that are equipped with hardware components like radio for communication, a CPU hardware to process tasks, sensors to be responsive to the globe within which they're located and to regulate it at a given instant. Even so, as sensible objects have restricted resource constraints to appoint sturdy protection mechanisms, they're at risk of subtle security attacks. For this reason, a smart authentication mechanism that considers every helpful resource constraints and safety is needed

Amaranth Starch Isolation, Oxidation, Heat-Moisture Treatment and Application in Edible Film Formation

Starch was isolated from amaranth grains and subjected to modification treatments. Oxidation of isolated starch was done using sodium hypochlorite and heat-moisture treatment was done at 85°C for 6hr keeping the moisture content 30% during treatment. Native and modified starches of amaranth were used for preparation of edible films and different characteristics of films were evaluated. Both the modification treatments increased tensile strength of amaranth starch films. Heat moisture treatment increased water vapour permeability while oxidation had contrary effects on amaranth starch films. Water solubility of films of amaranth starches was reduced by modification treatments of starches. Heat moisture treatments increased yellowness of starch films

Gastroprotective Properties of Karanjin from Karanja (Pongamia pinnata) Seeds; Role as Antioxidant and H+, K+-ATPase Inhibitor

Plant extracts are the most attractive sources of newer drugs and have been shown to produce promising results for the treatment of gastric ulcers. Karanjin, a furano-flavonoid has been evaluated for anti-ulcerogenic property by employing adult male albino rats. Karanjin (>95% pure) was administered to these rats in two different concentrations, that is, 10 and 20 mg kg−1 b.w. Ulcers were induced in the experimental animals by swim and ethanol stress. Serum, stomach and liver-tissue homogenates were assessed for biochemical parameters. Karanjin inhibited 50 and 74% of ulcers induced by swim stress at 10 and 20 mg kg−1 b.w., respectively. Gastric mucin was protected up to 85% in case of swim stress, whereas only 47% mucin recovery was seen in ethanol stress induced ulcers. H+, K+-ATPase activity, which was increased 2-fold in ulcer conditions, was normalized by Karanjin in both swim/ethanol stress-induced ulcer models. Karanjin could inhibit oxidative stress as evidenced by the normalization of lipid peroxidation and antioxidant enzyme (i.e., catalase, peroxidase and superoxide dismutase) levels. Karanjin at concentrations of 20 mg kg−1 b.w., when administered orally for 14 days, did not indicate any lethal effects. There were no significant differences in total protein, serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase and alkaline phosphatase between normal and Karanjin-treated rats indicating no adverse effect on major organs. During treatment schedule, animals remained as healthy as control animals with normal food and water intake and body weight gain

Polarographic Studies of Cd(II) & Pb(II) Complexes with 2,3-Dihydroxypyridine

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SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL HETEROCYCLIC MANNICH BASES

Various novel heterocyclic mannich bases were prepared by using Mannich reaction. Acetanilide was treated with substituted benzaldehyde and morpholine / methyl amine to give corresponding titled compounds in good yields. The synthesized compounds were characterized by physical properties and spectral studies (IR, 1H-NMR) and tested for antimicrobial activity against Escherichia coli, Bacillus subtilis by using cup plate method with reference to the standard Streptomycin. All the titled compounds show good antimicrobial activity

STUDY ON RISK FACTORS, CLINICAL AND THERAPEUTIC PROFILE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS IN GOVERNMENT GENERAL HOSPITAL

Objective: This study mainly aims to assess and evaluate risk factors, clinical and therapeutical profile in chronic obstructive pulmonary disease (COPD) patients and promote rational drug therapy; to identify the prevalence of COPD symptoms and to assess the drugs prescribed in treating COPD patients; and to evaluate patterns of diagnosing COPD in patients and determine the severity of COPD in patients using COPD assessment test (CAT). Methods: A prospective observational study conducted in government general hospital among 220 patients for 6 months. Data were collected from patients by CAT questionnaire through interviewing each subject. Results: The majority of the patients (36%) were in the age group of 71–80 years. Males are more prone to the COPD (91%). Most common initiation interdependence of these habits are 31–40 years and 61.8% are suffering with comorbidities. A total of 145 (65%) have social habits. About 68% of the patients are suffering from occupational exposure, 78% of the patients are suffering from old pulmonary problems. Conclusion: Clinical pharmacist main provision is providing care to individual patients by patient counseling, regarding the rational usage of drug and also providing proper education regarding the usage of nebulizers and creating awareness to the patients

Comparative evaluation of efficacy and safety of carboxymethylcellulose either alone or in combination with non-steroidal anti-inflammatory drug in the treatment of dry eye in a tertiary care teaching hospital

Background: Dry eye produces discomfort and reducedvision. The treatment of dry eyes has traditionally involved hydrating and lubricating artificial tears. The newer medications include non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of dry eye disorders. This study was designed to compare the effect of topical carboxymethylcellulose (CMC) alone or in combination with topical NSAID for the treatment of dry eye in a tertiary care teaching hospital.Methods: A total of 60 patients diagnosed with dry eye were enrolled for a study period of 1 year. Patient of either sex (male/female), age between 18 and 70 years, and all diagnosed cases of dry eye in ophthalmology outpatient department were selected. Patients (n=60) were stabilized on CMC for 2 weeks and thereafter divided into two groups. Group I (n=30) received only topical CMC; Group II (n=30) received CMC+NSAID. The patients were followed up to 12 weeks. Diagnostic tests included Schirmer’s test and tear break up time (TBUT). Ocular Surface Disease Index (OSDI) was used for assessing the Quality of Life. Analysis was done using GraphPad InStat software. p0.05) and TBUT test value (p>0.05) showed no significant difference while OSDI score revealed significant difference (p<0.05). Burning, stinging, blurring of vision, photophobia, and hyperemia were among the common adverse effects seen.Conclusion: Both groups showed significant improvement in Schirmer’s test and TBUT test value and OSDI score at the end of the study. Intergroup comparison showed a significant difference with reference to OSDI score. Patients receiving NSAID reported more adverse effects