Counting statistics of coherent population trapping in quantum dots

Destructive interference of single-electron tunneling between three quantum dots can trap an electron in a coherent superposition of charge on two of the dots. Coupling to external charges causes decoherence of this superposition, and in the presence of a large bias voltage each decoherence event transfers a certain number of electrons through the device. We calculate the counting statistics of the transferred charges, finding a crossover from sub-Poissonian to super-Poissonian statistics with increasing ratio of tunnel and decoherence rates.Comment: 4 pages, 2 figure

Transfer of autocollimator calibration for use with scanning gantry profilometers for accurate determination of surface slope and curvature of state of the art x ray mirrors

X ray optics, desired for beamlines at free electron laser and diffraction limited storage ring x ray light sources, must have almost perfect surfaces, capable of delivering light to experiments without significant degradation of brightness and coherence. To accurately characterize such optics at an optical metrology lab, two basic types of surface slope profilometers are used the long trace profilers LTPs and nanometer optical measuring NOM like angular deflectometers, based on electronic autocollimator AC ELCOMAT 3000. The inherent systematic errors of the instrument s optical sensors set the principle limit to their measuring performance. Where autocollimator of a NOM like profiler may be calibrated at a unique dedicated facility, this is for a particular configuration of distance, aperture size, and angular range that does not always match the exact use in a scanning measurement with the profiler. Here we discuss the developed methodology, experimental set up, and numerical methods of transferring the calibration of one reference AC to the scanning AC of the Optical Surface Measuring System OSMS , recently brought to operation at the ALS Xray Optics Laboratory. We show that precision calibration of the OSMS performed in three steps, allows us to provide high confidence and accuracy low spatial frequency metrology and not print into measurements the inherent systematic error of tool in use. With the examples of the OSMS measurements with a state of the art x ray aspherical mirror, available from one of the most advanced vendors of X ray optics, we demonstrate the high efficacy of the developed calibration procedure. The results of our work are important for obtaining high reliability data, needed for sophisticated numerical simulations of beamline performance and optimization of beamline usage of the optics. This work was supported by the U. S. Department of Energy under contract number DE AC02 05CH1123

Verkalkung der Falx cerebri: Ein pathognomonisches Zeichen beim Gorlin-Goltz-Syndrom

Zusammenfassung: Hintergrund: Das Gorlin-Goltz-Syndrom (syn. Basalzellnävussyndrom) ist ein autosomal-dominant vererbtes Krankheitsbild, das sich in charakteristischer Weise anhand von Keratozysten der Kiefer, multiplen Basaliomen, skelettalen Deformationen und intrakraniellen Kalzifizierungen manifestiert. Methode: In der vorliegenden Studie wurden 4787 Röntgenaufnahmen mit okzipitomentalem Strahlengang aus dem Archiv der Klinik für Zahn-, Mund- und Kieferheilkunde der Christian-Albrechts-Universität Kiel auf das Vorliegen von Kalzifikationen im Bereich der Falx cerebri geprüft. Ergebnisse: Dabei kristallisierten sich charakteristische Erscheinungsbilder dieser Abweichungen heraus, die 4 lamellaren Strukturgruppen zugeordnet werden konnten. Die Strukturen der Gruppe4 konnten nur bei Gorlin-Goltz-Syndrom-Patienten gefunden werden und unterschieden sich in Form und Ausmaß von den restlichen 3Gruppen. Schlussfolgerung: Das plurilamellare Erscheinungsbild dieser Gruppe konnte als pathognomonisches Zeichen für das Basalzellnävussyndrom gewertet werde

Computational Prediction of ω-Transaminase Specificity by a Combination of Docking and Molecular Dynamics Simulations

ω-Transaminases (ω-TAs) catalyze the conversion of ketones to chiral amines, often with high enantioselectivity and specificity, which makes them attractive for industrial production of chiral amines. Tailoring ω-TAs to accept non-natural substrates is necessary because of their limited substrate range. We present a computational protocol for predicting the enantioselectivity and catalytic selectivity of an ω-TA from Vibrio fluvialis with different substrates and benchmark it against 62 compounds gathered from the literature. Rosetta-generated complexes containing an external aldimine intermediate of the transamination reaction are used as starting conformations for multiple short independent molecular dynamics (MD) simulations. The combination of molecular docking and MD simulations ensures sufficient and accurate sampling of the relevant conformational space. Based on the frequency of near-attack conformations observed during the MD trajectories, enantioselectivities can be quantitatively predicted. The predicted enantioselectivities are in agreement with a benchmark dataset of experimentally determined ee% values. The substrate-range predictions can be based on the docking score of the external aldimine intermediate. The low computational cost required to run the presented framework makes it feasible for use in enzyme design to screen thousands of enzyme variants

Three-tangle for mixtures of generalized GHZ and generalized W states

We give a complete solution for the three-tangle of mixed three-qubit states composed of a generalized GHZ state, a|000>+b|111>, and a generalized W state, c|001>+d|010>+f|100>. Using the methods introduced by Lohmayer et al. we provide explicit expressions for the mixed-state three-tangle and the corresponding optimal decompositions for this more general case. Moreover, as a special case we obtain a general solution for a family of states consisting of a generalized GHZ state and an orthogonal product state

Image and Information Fusion Experiments with a Software-Defined Multi-Spectral Imaging System for Aviation and Marine Sensor Networks

The availability of Internet, line-of-sight and satellite identification and surveillance information as well as low-power, low-cost embedded systems-on-a-chip and a wide range of visible to long-wave infrared cameras prompted Embry Riddle Aeronautical University to collaborate with the University of Alaska Arctic Domain Awareness Center (ADAC) in summer 2016 to prototype a camera system we call the SDMSI (Software-Defined Multi-spectral Imager). The concept for the camera system from the start has been to build a sensor node that is drop-in-place for simple roof, marine, pole-mount, or buoy-mounts. After several years of component testing, the integrated SDMSI is now being tested, first on a roof-mount at Embry Riddle Prescott. The roof-mount testing demonstrates simple installation for the high spatial, temporal and spectral resolution SDMSI. The goal is to define and develop software and systems technology to complement satellite remote sensing and human monitoring of key resources such as drones, aircraft and marine vessels in and around airports, roadways, marine ports and other critical infrastructure. The SDMSI was installed at Embry Riddle Prescott in fall 2016 and continuous recording of long-wave infrared and visible images have been assessed manually and compared to salient object detection to automatically record only frames containing objects of interest (e.g. aircraft and drones). It is imagined that ultimately users of the SDMSI can pair with it via wireless to browse salient images. Further, both ADS-B (Automatic Dependent Surveillance-Broadcast) and S-AIS (Satellite Automatic Identification System) data are envisioned to be used by the SDMSI to form expectations for observing in future tests. This paper presents the preliminary results of several experiments and compares human review with smart image processing in terms of the receiver-operator characteristic. The system design and software are open architecture, such that other researchers are encouraged to construct and participate in sharing results and networking identical or improved versions of the SDMSI for safety, security and drop-in-place scientific image sensor networking

Qualitative Comparative Analysis (QCA) and Sociology - Perspectives, Potential, and Areas of Application

Qualitative Comparative Analysis (QCA) wurde von dem Soziologen Charles C. Ragin als Verbindung von fallorientierten, konfigurativen Ansätzen und mengentheoretischem Denken präsentiert. Mittlerweile hat sich QCA – von Ragin und anderen weiterentwickelt – als mengentheoretischer Ansatz zur Untersuchung sozialer Phänomene im sozialwissenschaftlichen Methodenkanon etabliert. Der vorliegende Beitrag zielt darauf ab, Forschungsperspektiven und -potentiale von QCA als (relativ) junge Methode für soziologische Fragestellungen aufzuzeigen. Auf der Grundlage einer Rundschau von 77 publizierten, soziologischen Zeitschriftenartikeln wird einerseits ein breiter Überblick über Anwendungsbereiche, aktuelle Trends und Entwicklungen von QCA in der Soziologie gegeben. Andererseits werden am Beispiel der publizierten Studien die einzelnen Analyseschritte einer QCA besprochen und dabei gängige Fallstricke aufgezeigt, wobei sowohl practiced practices und auch best practices in ihrer Anwendung herausgearbeitet werden.The sociologist Charles C. Ragin presented Qualitative Comparative Analysis (QCA) combining ideas of case-oriented research, configurational thinking, and set-theoretical logic. Since then – being further developed by Ragin and others – QCA as a set-theoretical approach to analyze social phenomena has become an established tool within social science methodology. This paper aims at highlighting perspectives and potentials QCA as a (relatively) new method is able to offer for addressing sociological research questions. In order to do so, 77 publications in the field of sociology are reviewed. On this basis, on the one hand, a broad overview is given regarding applications, trends, and developments of QCA. On the other hand, crucial steps within every QCA are examined and potential pitfalls discussed by exemplifying practiced practices and best practices

Interplay of Andreev reflection and Coulomb blockade in hybrid superconducting single electron transistors

We study the interplay between Coulomb blockade and superconductivity in a tunable superconductor-superconductor-normal metal single-electron transistor. The device is realized by connecting the superconducting island via an oxide barrier to the normal metal lead and with a break junction to the superconducting lead. The latter enables Cooper pair transport and (multiple) Andreev reflection. We show that those processes are relevant also far above the superconducting gap and that signatures of Coulomb blockade may reoccur at high bias while they are absent for small bias in the strong-coupling regime. Our experimental findings agree with simulations using a master equation approach in combination with the full counting statistics of multiple Andreev reflection.Comment: Manuscript only, supplement available upon reques