767 research outputs found

    Communication Through Motion: Legibility of Multi-Robot Systems

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    The interaction between a user and a multi-robot system in a shared environment is a relatively uncharted topic. But, as these types of systems will increase in the future years, an efficient way of communication is necessary. To this aim, it is interesting to discover if a multi-robot system can communicate its intentions exploiting only some motion-variables, which are characteristics of the motion of the robots. This study is about the legibility of a multi-robot system: In particular, we focus on the influence of these motion-variables on the legibility of more than one group of robots that move in a shared environment with the user. These motion-variables are: Trajectory, dispersion and stiffness. They are generally used to define the motion of a group of mobile robots. Trajectory and dispersion were found relevant for the correctness of the communication between the user and the multi-robot system, while stiffness was found relevant for the rapidity of communication. The analysis of the influence of the motion-variables was carried out with an ANOVA (analysis of variance) based on a series of data coming from an experimental campaign conducted in a virtual reality set-up

    New, efficient, and accurate high order derivative and dissipation operators satisfying summation by parts, and applications in three-dimensional multi-block evolutions

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    We construct new, efficient, and accurate high-order finite differencing operators which satisfy summation by parts. Since these operators are not uniquely defined, we consider several optimization criteria: minimizing the bandwidth, the truncation error on the boundary points, the spectral radius, or a combination of these. We examine in detail a set of operators that are up to tenth order accurate in the interior, and we surprisingly find that a combination of these optimizations can improve the operators' spectral radius and accuracy by orders of magnitude in certain cases. We also construct high-order dissipation operators that are compatible with these new finite difference operators and which are semi-definite with respect to the appropriate summation by parts scalar product. We test the stability and accuracy of these new difference and dissipation operators by evolving a three-dimensional scalar wave equation on a spherical domain consisting of seven blocks, each discretized with a structured grid, and connected through penalty boundary conditions.Comment: 16 pages, 9 figures. The files with the coefficients for the derivative and dissipation operators can be accessed by downloading the source code for the document. The files are located in the "coeffs" subdirector

    DNS of Turbulent Heat Transfer in Impinging Jets at Different Reynolds and Prandtl Numbers

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    The heat transfer between an impinging circular jet and a flat plate is studied by means of direct numerical simulations (DNS) for different Prandtl numbers of the fluid. The thermal field is resolved for Pr= 1, 0.72, 0.025, and 0.01. The flow is incompressible and the temperature is treated as a passive scalar field. The jet originates from a fully developed turbulent pipe flow and impinges perpendicularly on a smooth solid heated plate placed at two pipe diameters distance from the jet exit section. The values of Reynolds numbers based on the pipe diameter and bulk mean velocity in the pipe are set to Re= 5300 and Re= 10000. Inflow boundary conditions are enforced using a precursor simulation. Heat transfer at the wall is addressed through the Nusselt number distribution and main flow field statistics. At fixed Reynolds number it is shown that the Prandtl number influences the intensity of the Nusselt number at a given radial location, and that the Nusselt number distribution along the plate exhibit similar features at different Prandtl numbers. The characteristic secondary peak in the Nusselt number distribution is found for both Reynolds numbers for Pr= 0.025 and Pr = 0.01. All the simulations presented in this study were performed with the high order spectral element code Nek5000. Generated flow field statistics are available in the open access repository KITOpen

    Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression

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    Background: Operational tolerance is an alternative to lifelong immunosuppression after transplantation. One strategy to achieve tolerance is by T regulatory cells. Safety and feasibility of a T regulatory type 1 (Tr1)-cell-based therapy to prevent graft versus host disease in patients with hematological malignancies has been already proven. We are now planning to perform a Tr1-cell-based therapy after kidney transplantation. Methods: Upon tailoring the lab-grade protocol to patients on dialysis, aims of the current work were to develop a clinical-grade compatible protocol to generate a donor-specific Tr1-cell-enriched medicinal product (named T10 cells) and to test the Tr1-cell sensitivity to standard immunosuppression in vivo to define the best timing of cell infusion. Results: We developed a medicinal product that was enriched in Tr1 cells, anergic to donor-cell stimulation, able to suppress proliferation upon donor- but not third-party stimulation in vitro, and stable upon cryopreservation. The protocol was reproducible upon up scaling to leukapheresis from patients on dialysis and was effective in yielding the expected number of T10 cells necessary for the planned infusions. The tolerogenic gene signature of circulating Tr1 cells was minimally compromised in kidney transplant recipients under standard immunosuppression and it eventually started to recover 36weeks post-transplantation, providing rationale for selecting the timings of the cell infusions. Conclusions: These data provide solid ground for proceeding with the trial and establish robust rationale for defining the correct timing of cell infusion during concomitant immunosuppressive treatment

    On the well posedness of the Baumgarte-Shapiro-Shibata-Nakamura formulation of Einstein's field equations

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    We give a well posed initial value formulation of the Baumgarte-Shapiro-Shibata-Nakamura form of Einstein's equations with gauge conditions given by a Bona-Masso like slicing condition for the lapse and a frozen shift. This is achieved by introducing extra variables and recasting the evolution equations into a first order symmetric hyperbolic system. We also consider the presence of artificial boundaries and derive a set of boundary conditions that guarantee that the resulting initial-boundary value problem is well posed, though not necessarily compatible with the constraints. In the case of dynamical gauge conditions for the lapse and shift we obtain a class of evolution equations which are strongly hyperbolic and so yield well posed initial value formulations

    On the inviscid and non-resistive limit for the equations of incompressible magnetohydrodynamics

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    We prove the convergence of the solutions for the incompressible homogeneous magnetohydrodynamics (MHD) system to the solutions to ideal MHD one in the inviscid and non-resistive limit, detailing the explicit convergence rates. For this study we consider a fluid occupying the whole space R3 and we assume that the viscosity effects in this fluid can be described by two different operators: the usual Laplacian operator affected by the inverse of the Reynolds number or by a viscosity operator introduced by S. I. Braginskii in 1965

    Quantization of Acoustic Modes in Dumbbell Nanoparticles

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    Well-Posed Initial-Boundary Evolution in General Relativity

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    Maximally dissipative boundary conditions are applied to the initial-boundary value problem for Einstein's equations in harmonic coordinates to show that it is well-posed for homogeneous boundary data and for boundary data that is small in a linearized sense. The method is implemented as a nonlinear evolution code which satisfies convergence tests in the nonlinear regime and is robustly stable in the weak field regime. A linearized version has been stably matched to a characteristic code to compute the gravitational waveform radiated to infinity.Comment: 5 pages, 6 figures; added another convergence plot to Fig. 2 + minor change
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