Invasive maxillary sinus aspergillosis: a case report successfully treated with voriconazole and surgical debridement

Introduction: Invasive aspergillosis of the paranasal sinuses is a rare disease and often misdiagnosed; however, its incidence has seen substancial growth over the past 2 decades. Definitive diagnosis of these lesions is based on histological examination and fungal culture. Case Report: An 81-year-old woman with a history of pain in the left maxillary region is presented. The diagnosis was invasive maxillary aspergillosis in immunocompetent patient, which was successfully treated with voricona - zole and surgical debridement. Possible clinical manifestations, diagnostic imaging techniques and treatment used are discussed. Since the introduction of voriconazole, there have been several reports of patients with invasive aspergillosis who responded to treatment with this new antifungal agent. Conclusions: We report the importance of early diagnosis and selection of an appropriate antifungal agent to achie - ve a successful treatment

Semilinear problems for the fractional laplacian with a singular nonlinearity

The aim of this paper is to study the solvability of the problem (-Δ)s u = F(x,u) := λ f(x)/uγ + Mup in ω u > 0 in ω, u = 0 in RN \ ω, where Ω is a bounded smooth domain of RN, N > 2s, M ε {0, 1}, 0 0, λ > 0, p > 1 and f is a nonnegative function. We distinguish two cases: - For M = 0, we prove the existence of a solution for every γ > 0 and λ > 0. A1 - For M = 1, we consider f ≡ 1 and we find a threshold ∧ such that there exists a solution for every 0 ∧Work partially supported by project MTM2013-40846-P MINECO. The third author is also supported for the grant BES-2011-044216 associated to MTM2010-1812

A Mosquito is Worth 16x16 Larvae: Evaluation of Deep Learning Architectures for Mosquito Larvae Classification

Mosquito-borne diseases (MBDs), such as dengue virus, chikungunya virus, and West Nile virus, cause over one million deaths globally every year. Because many such diseases are spread by the Aedes and Culex mosquitoes, tracking these larvae becomes critical in mitigating the spread of MBDs. Even as citizen science grows and obtains larger mosquito image datasets, the manual annotation of mosquito images becomes ever more time-consuming and inefficient. Previous research has used computer vision to identify mosquito species, and the Convolutional Neural Network (CNN) has become the de-facto for image classification. However, these models typically require substantial computational resources. This research introduces the application of the Vision Transformer (ViT) in a comparative study to improve image classification on Aedes and Culex larvae. Two ViT models, ViT-Base and CvT-13, and two CNN models, ResNet-18 and ConvNeXT, were trained on mosquito larvae image data and compared to determine the most effective model to distinguish mosquito larvae as Aedes or Culex. Testing revealed that ConvNeXT obtained the greatest values across all classification metrics, demonstrating its viability for mosquito larvae classification. Based on these results, future research includes creating a model specifically designed for mosquito larvae classification by combining elements of CNN and transformer architecture.Comment: 6 pages, 5 figures, 4 tables. Image dataset, fine-tuning code, and pre-trained models are available at https://github.com/thenerd31/vit-cnn-mosquito-image-classificatio

Cavernous hemangioma of the parotid gland in adults

Hemangiomas account for 0.4-0.6% of all tumors of the parotid gland and most of them occur in children, never - theless in adults hemangiomas are very rare. We report the case of a 62 year old woman with a mass in the parotid right tail associated with fluctuating swelling episodes unrelated to meals and with a slowly progressive growth. The provisional diagnosis was a pleomorphic adenoma, so a right superficial parotidectomy was performed. During surgery, the macroscopic appearance makes suspect a vascular lesion. The histopathological result was a cavernous hemangioma. The classic clinical presentation of a parotid hemangioma is an intraglandular mass associated or not with skin lesions characterized by reddish macules and/or papules, and a vibration or pulsation when palpating the parotid region. In imaging tests, phleboliths could be observed which are very suggestive of a hemangioma or a vascular malformation. In the absence of these signs, the diagnosis could be difficult, particularly in an adult due to its low prevalence, with about 50 cases reported worldwide. However a hemangioma should be considered in the differential diagnosis of parotid tumors in adults

Effect of Shot Peening on Oxidation and Precipitation in Inconel 718

In this study, the effect of the surface state on the behaviour of Inconel 718 alloy exposed to 640 ∘ C and 700 ∘ C environments for times varying between one and one hundred hours was investigated. In particular, the focus was set on the evolution of oxidation and precipitation phenomena during thermal exposure. Three surface states were considered: two generated through shot peening treatments featuring different coverage levels, while the third condition is a non-peened one. Shot peening treatments modify the surface condition and introduce higher residual stresses and microhardness values than in the non-treated condition. The morphology of the oxides appears to be different depending on the condition observed. Regarding the kinetics, over time the oxidation process follows a parabolic trend and appears to be influenced by the surface state; in particular, severe shot peening treatment is characterized by the highest intensity of the phenomenon. However, the order of magnitude of the weight gains measured suggests that the observed variations can be neglected, and that the positive effect of shot peening can be exploited without introducing oxidation problems. From the point of view of the microstructural evolution, an increase in the coarsening kinetics of γ ” phase was observed in the shot peened layer

Linfoma angiocéntrico centrofacial

El linfoma angiocéntrico centrofacial es una neoplasia linfoide rara, con un diagnóstico a menudo difícil, debido al cuadro clínico inespecífico y a que muchas veces son necesarias varias biopsias para llegar a un diagnóstico correcto. Se trata de un linfoma no Hodgkin(LNH) agresivo, de localización preferente en el tracto respiratorio superior (sobre todo en cavidad nasal), y con un pronóstico ominoso, ya que la supervivencia media es de 12-18 meses aproximadamente(1). Predomina en orientales y sudamericanos, entre los 50-60 años de edad, y con ligera preferencia por el sexo masculino (2:1). Se presenta el caso de una paciente ecuatoriana que acude a nuestro servicio con edema hemifacial, rinorrea achocolatada y obstrucción respiratoria nasal de 1 mes de evolución, sin respuesta al tratamiento antibiótico y antiinflamatorio, que tras realizar varias pruebas diagnósticas se evidenció histológicamente la presencia de un linfoma T extranodal de tipo nasal (también llamado linfoma de células T angiocéntrico).The centrofacial angiocentric lymphoma is a rare lymphoid neoplasm, with an often-difficult diagnosis due to the non-specific clinical picture. On many occasions it is necessary to perform various biopsies to reach the correct diagnosis. This lymphoma is an aggressive Non-Hodgkin's (NHL) type, which is normally found in the upper respiratory tract (predominantly in the nasal cavity), and has an ominous prognosis, as the average survival rate is between 12 and 18 months (1). It is predominantly found in subjects of oriental and South American extraction, who are between the ages of 50 and 60 years and with a slight tendency towards males (2:1). This is the case study of a female Ecuadorian patient who was referred to our department with a hemifacial edema, chocolate- like rhinorrhea and nasal respiratory obstruction, which had been treated with antibiotics and anti-inflammatories for a month without success. After performing a number of diagnostic tests, it was found histologically that the patient had an extranodal T-cell lymphoma of the nasal type (also known as T-cell angiocentric lymphoma)

Frontal sinus mucocele with intracranial and intraorbital extension

ABSTRACT Introduction: Frontal sinus mucoceles can present with a multitude of different symptoms including ophthalmic disturbances. Even benign, they have a tendency to expand by eroding the surrounding bony walls that displaces and destroys structures by pressure and bony resorption. Case report: A 32-year-old man with diplopia, proptosis of the right eye and headache was presented. The diagnosis was frontal sinus mucocele with intracranial and intraorbital extension. Possible clinical manifestations of mucoceles, diagnostic imaging techniques and treatment used are discussed. Conclusion: Frontal mucoceles are benign and curable, early recognition and management of them is of paramount importance, because they can cause local, orbital or intracranial complications

Frontal sinus mucocele with intracranial and intraorbital extension

ABSTRACT Introduction: Frontal sinus mucoceles can present with a multitude of different symptoms including ophthalmic disturbances. Even benign, they have a tendency to expand by eroding the surrounding bony walls that displaces and destroys structures by pressure and bony resorption. Case report: A 32-year-old man with diplopia, proptosis of the right eye and headache was presented. The diagnosis was frontal sinus mucocele with intracranial and intraorbital extension. Possible clinical manifestations of mucoceles, diagnostic imaging techniques and treatment used are discussed. Conclusion: Frontal mucoceles are benign and curable, early recognition and management of them is of paramount importance, because they can cause local, orbital or intracranial complications