Genetics of randomly bred cats support the cradle of cat domestication being in the Near East

Cat domestication likely initiated as a symbiotic relationship between wildcats (Felis silvestris subspecies) and the peoples of developing agrarian societies in the Fertile Crescent. As humans transitioned from hunter-gatherers to farmers ~12,000 years ago, bold wildcats likely capitalized on increased prey density (i.e., rodents). Humans benefited from the cats’ predation on these vermin. To refine the site(s) of cat domestication, over 1000 random-bred cats of primarily Eurasian descent were genotyped for single-nucleotide variants and short tandem repeats. The overall cat population structure suggested a single worldwide population with significant isolation by the distance of peripheral subpopulations. The cat population heterozygosity decreased as genetic distance from the proposed cat progenitor’s (F.s. lybica) natural habitat increased. Domestic cat origins are focused in the eastern Mediterranean Basin, spreading to nearby islands, and southernly via the Levantine coast into the Nile Valley. Cat population diversity supports the migration patterns of humans and other symbiotic species

Clays in Denizli region (southwestern Anatolia), Turkey

In this region, marine, continental and lacustrine clay deposits which are used as a raw material in the cement sector were investigated. It is seen that Upper Cretaceous-Upper Eocene shales representing marine deposition are found in Malidagi in economic quantities, However, their Na(2)O% and K(2)O% contents are higher than in other clays. The Oligocene aged Bayiralan clay representing marine deposition have abundant magnesian minerals. Because of its high MgO% content, this clay is not suitable cement standard. The areal extent of the Upper Miocene-Lower Pliocene Kizilburun clays represented fine sediments in the floodplain are widely situated. These may be used in cement sector, but the have reserve and environmental problems. The red coloured clays belonging to the Pliocene Sakizcilar Formation are sutitable for cement standard. To decreasing the transportation costs of the Denizli cement factory, the Malidagi clay and Sakizcilar clay may be used together in different proportions, If the Malidagi and Sakizcilar clays may be used, the contents of K(2)O% and Na(2)O% will decrease

J Occup Environ Med

Objective:There is growing interest in the NIOSH Total Worker Health\uae (TWH) program, specifically in the process of designing and implementing safer, health-promoting work and workplaces. A TWH Research Methodology Workshop was convened to discuss research methods and future needs.Methods:Twenty-six experts in occupational safety and health and related fields reviewed and discussed current methodological and measurement issues and those showing promise.Results:TWH intervention studies face the same challenges as other workplace intervention studies and some unique ones. Examples are provided of different approaches and their applications to TWH intervention studies, and desired developments in the TWH literature.Conclusions:This report discusses and outlines principles important to building the TWH intervention research base. Rigorous, valid methodologic and measurement approaches are needed for TWH intervention as well as for basic/etiologic, translational, and surveillance research.U19 OH011227/OH/NIOSH CDC HHS/United StatesU60OH009762/ACL HHS/United StatesP30 ES005605/ES/NIEHS NIH HHS/United StatesU19 OH008857/OH/NIOSH CDC HHS/United StatesU60 OH009762/OH/NIOSH CDC HHS/United StatesU19 OH008868/OH/NIOSH CDC HHS/United StatesU19OH011232/ACL HHS/United StatesU19 OH008861/OH/NIOSH CDC HHS/United StatesU19 OH010154/OH/NIOSH CDC HHS/United StatesCC999999/Intramural CDC HHS/United StatesU48 DP005008/DP/NCCDPHP CDC HHS/United StatesU19OH008868/ACL HHS/United States2019-11-01T00:00:00Z30407366PMC6221402691

Clays in Denizli region (southwestern Anatolia), Turkey

In this region, marine, continental and lacustrine clay deposits which are used as a raw material in the cement sector were investigated. It is seen that Upper Cretaceous-Upper Eocene shales representing marine deposition are found in Malidagi in economic quantities, However, their Na(2)O% and K(2)O% contents are higher than in other clays. The Oligocene aged Bayiralan clay representing marine deposition have abundant magnesian minerals. Because of its high MgO% content, this clay is not suitable cement standard. The areal extent of the Upper Miocene-Lower Pliocene Kizilburun clays represented fine sediments in the floodplain are widely situated. These may be used in cement sector, but the have reserve and environmental problems. The red coloured clays belonging to the Pliocene Sakizcilar Formation are sutitable for cement standard. To decreasing the transportation costs of the Denizli cement factory, the Malidagi clay and Sakizcilar clay may be used together in different proportions, If the Malidagi and Sakizcilar clays may be used, the contents of K(2)O% and Na(2)O% will decrease

Comparisons of serum somatotropin, 3,5,3 '-triiodothyronine, thyroxine, total protein and free fatty acid levels in newborn Sakiz lambs separated from or suckling their dams

Objective: To determine the effects on serum somatotropin, 3,5,3'-triiodothyronine (T-3), thyroxine (T-4), free fatty acids (FFAs) and total protein levels of different feedings and age in Sakiz sheep that have a high twin-bearing rate supported by estrous synchronization. Methods: 20 newborn lambs were used in the study. Lambs were divided into 2 equal groups. The lambs in 1 group were separated from their dams following parturition, and those in other group were kept together with their dams. Separated lambs were fed commercial cow's milk for 2.5 weeks. After that, they were fed a milk substitute, hay and concentrated supplement for 2 months, and from the end of the 2 months they were fed hay and concentrated supplement. The lambs in other group were kept together with their dams only during the day and in addition were fed hay and concentrated supplement. After 2 months, they were maintained feeding only on hay and concentrated supplement. Blood samples were taken from vena jugularis of lambs at 12 and 24-48 h, and 14, 28, 42 and 56-90 days after parturition. Serum samples were analyzed for somatotropin by enzyme immunoassay, for T-3 and T-4 by radioimmunoassay, and for total protein and FFA by a spectrophotometric method. Results: Serum somatotropin levels were insignificantly different between the lambs with and without their dams. Serum T-3 levels were generally lower in the separated lambs than those in other group. Serum T-4 levels were significantly lower in the separated lambs 48 h and 90 days after parturition than those in other group. Serum FFAs were insignificantly different between 2 groups. Serum total protein concentrations were lower in the separated lambs than lambs kept together with their dams (significantly at 12 and 48 h and 14 days). Conclusion: Ingestion of colostrum and dam milk markedly affected serum total protein levels, but body weight and serum somatotropin levels were insignificantly affected. Also serum T-3 and T-4 levels markedly decreased with advancing age. Serum FFA levels were not affected by the trial. Copyright (C) 2005 S. Karger AG, Basel

Lenz microphthalmia syndrome with dental anomalies: A case report

PubMed ID: 14998213This report describes the dental management and 7-year follow-up of a 14-year-old boy who showed the typical characteristics of Lenz microphthalmia syndrome, a rare genetic disorder characterized by multiple abnormalities. The main features of the syndrome are microphthalmia, developmental retardation, ear abnormalities, microcephaly, skeletal, digital and urogenital anomalies. The dental anomalies include micrognathia, hypodontia, agenesis of permanent teeth, conic-shaped incisors, and taurodontic molars. The purpose of the report was to document specific oral manifestations and dental anomalies and their management associated with a previously reported case

processes in a back-arc setting

Mineral assemblages of both cognate inclusions and host-lamprophyres with lamproitic affinity in Kocapinar district (Denizli), Western Anatolia, consist of phlogopitic mica, diopsidic clinopyroxene, K-feldspar, apatite, opaque and carbonates (calcite-dolomite). Two distinct types of cognate inclusions have been defined in host lamprophyres: clinopyroxene-rich (CCI) and clinopyroxene-phlogopite-rich (CPCI). Whole-rock compositions of inclusions show a near-primitive nature with high MgO (7.56-15.1 wt.%), Cr (195-2270 ppm), Ni (213-335 ppm) contents and a potassic character [K2O (2.0-2.8 wt.%) > Na2O (0.4-2.2 wt.%)]. Data imply that the inclusions crystallized from magmas formed by melting of phlogopite-bearing pyroxenites in a peri-dotitic mantle source, however, the presence of reverse-zoning in clinopyroxenes with salitic Fe-rich green cores in host-lamprophyres and CPCI inclusions suggest that the Denizli lavas represent mixtures of distinct (probably ultrapotassic and alkali basaltic) magmas. Estimated geobarometric constraints inferred from clinopyroxene compositions in CCI and CPCI inclusions indicate moderate pressures of pyroxene crystallization (ranging between 1.7 and 2.2 GPa and corresponding to 53-70 km depths) under low pressure magma fractionation. Results reveal that i) the origin of Denizli lamprophyres with transitional (between arc-type and intra-plate-type) geochemical signatures is consistent with a shallow level mantle petrogenesis, rather than a deep-seated origin related to mantle convection, ii) the source was a highly refractory and metasomatized peridotitic mantle present at the base of the lower crust, iii) metasomatic agents that affected the mantle lithosphere beneath Denizli region are distinct from those beneath other western Anatolia orogenic centers, and iv) the transitional character of Kocapinar (Denizli) lamprophyric rocks were probably formed as a result of either underplating or contamination of asthenospheric magma at the base of the mantle lithosphere, or assimilation of delaminated continental edge-lithospheric mantle via ascending asthenosphere. Denizli lamprophyres are interpreted to have formed during the formation of a basin/graben structure in the Latest Miocene-Early Pliocene, just after Late Miocene exhumation of Menderes massif. (C) 2012 Elsevier B.V. All rights reserved