CCD photometry of 2060 Chiron, 1991 January

Observations of 2060 Chiron was performed on 7 to 8 Jan. 1991 with the Mt. Palomar 1.52 m telescope in the Gunn-R passband. On-chip field stars were used to perform differential reductions. The repeatability of the 5.9 hour light curve was excellent, both within a night and from night to night. No evidence for short-term secular variations similar to those seen last year by both Luu and Jewitt (1990) and Buratti and Dunbar (1991) is seen in the new light curve. Chiron's rotational light curve appears strikingly similar to that obtained a year earlier by Luu and Jewitt (1990), both in amplitude and shape. Both light curves show strongly correlated changes over a timescale of perhaps 15 minutes. These same features were marginally visible in the 1986 light curve. Such behavior is believed to be evidence that Chiron may be more aspherical than the 4 percent intensity variation might otherwise indicate, and favors a viewing geometry where the subearth latitude is rather low. Chiron was much fainter in 1985, when a partial light curve was obtained by Marcialis. Due to the lower sampling rate of these early data, no conclusions can be made regarding the high-frequency light curve structure back then. All three of these light curves differ significantly from that obtained by Buratti and Dunbar (1991), one week before the observations of Luu and Jewitt. The Chiron field was calibrated using Landolt standards on Ut 15 Mar. 1991. A mean R-magnitude of 15.6 + or - 0.1 was found. Variability of 2060 Chiron was demonstrated over timescales of minutes, hours, and years. An intense campaign was urged to monitor the photometric behavior of Chiron throughout the 1990s

The future of Cybersecurity in Italy: Strategic focus area

This volume has been created as a continuation of the previous one, with the aim of outlining a set of focus areas and actions that the Italian Nation research community considers essential. The book touches many aspects of cyber security, ranging from the definition of the infrastructure and controls needed to organize cyberdefence to the actions and technologies to be developed to be better protected, from the identification of the main technologies to be defended to the proposal of a set of horizontal actions for training, awareness raising, and risk management

Persistent elevation of urine aquaporin-2 during water loading in a child with nephrogenic syndrome of inappropriate antidiuresis (NSIAD) caused by a R137L mutation in the V2 vasopressin receptor

Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) is a novel disease caused by a gain-of-function mutation in the V2 vasopressin receptor (V2R), which results in water overload and hyponatremia. We report the effect of water loading in a 3-year old boy with NSIAD, diagnosed in infancy, to assess urine aquaporin-2 (AQP2) excretion as a marker for V2R activation, and to evaluate the progression of the disease since diagnosis. The patient is one of the first known NSIAD patients and the only patient with a R137L mutation. Patient underwent a standard water loading test in which serum and urine sodium and osmolality, serum AVP, and urine AQP2 excretion were measured. The patient was also evaluated for ad lib fluid intake before and after the test. This patient demonstrated persistent inability to excrete free water. Only 39% of the water load (20 ml/kg) was excreted during a 4-hour period (normal ≥ 80-90%). Concurrently, the patient developed hyponatremia and serum hypoosmolality. Serum AVP levels were detectable at baseline and decreased one hour after water loading; however, urine AQP2 levels were elevated and did not suppress normally during the water load. The patient remained eunatremic but relatively hypodipsic during ad lib intake. In conclusion, this is the first demonstration in a patient with NSIAD caused by a R137L mutation in the V2R that urine AQP2 excretion is inappropriately elevated and does not suppress normally with water loading. In addition, this is the first longitudinal report of a pediatric patient with NSIAD diagnosed in infancy who demonstrates the ability to maintain eunatremia during ad lib dietary intake

The Discovery of Two New Satellites of Pluto

Pluto's first known moon, Charon, was discovered in 1978 (Christy 1978) and has a diameter about half that of Pluto (Buie 1992,Young 1994, Sicardy 2005), which makes it larger relative to its primary than any other moon in the Solar System. Previous searches for other satellites around Pluto have been unsuccessful (Stern 1991, Stern 1994, Stern 2003), but they were not sensitive to objects <=150 km in diameter and there are no fundamental reasons why Pluto should not have more satellites (Stern 1994). Here we report the discovery of two additional moons around Pluto, provisionally designated S/2005 P1 (hereafter P1) and S/2005 P2 (hereafter P2), which makes Pluto the first Kuiper belt object (KBO) known to have multiple satellites. These new satellites are much smaller than Charon (diameter~1200 km), with P1 ranging in diameter from 60-165 km depending on the surface reflectivity, and P2 about 20% smaller than P1. Although definitive orbits cannot be derived, both new satellites appear to be moving in circular orbits in the same orbital plane as Charon, with orbital periods of ~38 days (P1) and ~25 days (P2). The implications of the discovery of P1 and P2 for the origin and evolution of the Pluto system, and for the satellite formation process in the Kuiper belt, are discussed in a companion paper (Stern 2006).Comment: Preprint of a paper accepted for publication in the journal Natur

Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study

Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P &lt; 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P &lt; 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk

Replacement algorithms for fingerprint template update

Semi-supervised fingerprint template update is a relatively novel topic in which the problem of template representativeness with respect to unknown data has been pointed out. Current approaches to template update are based on insertion of a novel template into the gallery, and/or fusion of the template with an existing one. The automatic replacement of an existing template by a novel one is another possibility which has not yet been investigated. This paper is a first attempt to study the feasibility of using some template replacement algorithms in fingerprint verification systems. Replacement is performed online, which can be considered as a sort of “worst case” for this approach. Preliminary experiments are carried out on the four data sets of FVC2002 event

Online and offline fingerprint template update using minutiae: an experimental comparison

Although the template fingerprint collected during the registration phase of personal verification systems can be considered in principle as representative of the subject identity, some recent works pointed out that it is not completely able to follow the intra-class variations of the fingerprint shape. Accordingly, making these systems adaptive to these variations is one of the most interesting problems, and is often called as the “template updating” problem. In this paper, two different approaches for fingerprint template updating are compared by experiments. The first one, already proposed in other works, relies on the concept of ”online” template updating, that is, the fingerprint template is updated when the system is operating. As alternative, we propose the “offline” template update, which requires the collection of a representative batch of samples when the system is operating. They concur to the template updating when the system is offline, that is, it is not operating. Preliminary experiments carried out on the FVC data sets allow to point out some differences among the investigated approache

Template Selection by Editing Algorithms: a Case Study in Face Recognition

In this paper, we consider the problem of template selection in biometric systems as analogous to the problem, called “editing”, of selecting representative prototypes when using the 1-Nearest Neighbour classifier (NN). Four editing algorithms are used and compared by experiments with state-of-the-art template selection algorithms. Experiments are performed on a benchmark face data set. Reported results show pros and cons of editing algorithms for template selection in biometric systems