Nursing care for a 41-year-old patient suffering from breast cancer in a hospital setting

Breast cancer is the most common cause of cancer-related deaths among women in the world. Its occurrence is mainly influenced by environmental factors, and to a lesser extent by genetic factors. The gold standard in diagnosis is mammography, but special attention should be paid to the need to educate women at an increasingly younger age in the field of breast self-examination. Treatment for breast cancer includes surgery, radiotherapy, chemotherapy and hormone therapy. &nbsp

The influence of fine fractions content in non-cohesive soils on their compactibility and the CBR value

The bearing capacity of subsoils is particularly important due to the intensive development of road and airfield pavements. Subgrade is classified due to frost susceptibility as non-frost-susceptible, low-frost-susceptible or frost-susceptible. Presented research included laboratory tests of low-frost-susceptible soils with limited potential for direct use. The main objective of this paper was focused on the study of changes of compactibility parameters and the CBR (Californian Bearing Ratio) values of silty sand (Pπ). For this purpose, seventeen soil samples with various fine fractions content (of 1.6% to 24.2%), were composed. Laboratory tests, based on soaked soil samples, encompassed the Proctor Compaction test and the CBR test. Additionally, measurements of moisture content in soaked soil samples before and after the penetration test and the displacement of annular surcharge rings while penetration test, were performed. Obtained results allowed for conclusions that penetration curves diverge from the standard curve locally, therefore direct reading of the CBR values from the penetration curves may lead to its significant overstatement. There was also noticed the dependence between the water flow in the soil and the fine fraction content. The research recognized the need for pressure measurement in soil samples during the penetration test

Ecological risk assessment of chemical contaminants in stormwater sediments

Contaminants bound to suspended solids transported by stormwater pose quantity and quality problems to the water ecosystem. Therefore, it is necessary to carry out an ecological risk assessment. Currently, Polish legal regulations do not require that stormwater sediments should be tested for hazardous substances prior to their removal. Ecological evaluation was performed for polycyclic aromatic hydrocarbons (PAHs) and heavy metals in the sediments from three selected stormwater sedimentation tanks located in urban catchment areas of Kielce city. The purpose this study was to analyze sediments for chemical contaminants and to demonstrate the relationship between contaminant levels and physical attributes of the catchment, including land use, drainage area, age of catchment and impervious surface in the watershed. Levels of PAHs and heavy metals (Cd, Cr, Ni, Pb and Zn) in stormwater sediments were then compared with Polish regulations and ecological screening values to determine their potential risk to environment were established. The results of the current study suggest that stormwater sediments are moderately contaminated with PAHs and heavy metals according to domestic regulations. They are, however, highly contaminated according to ecological benchmarks, which are exceeded several times

Sulfolane: Magic Extractor or Bad Actor? Pilot-Scale Study on Solvent Corrosion Potential

The sulfur-containing derivatives and their metabolites, regarded as ‘old devils of green’ chemistry, constitute a relevant class of air/water/soil contaminants in over-polluted world. In fact, some industrially-engineered solvents have become environmentally unfavorable. An attractive alternative to commonly used industrial liquids is sulfolane (C4H8SO2), an anthropogenic medium. The main objective of this paper is the comprehensive review focusing mainly on the state-of-the-art aspects of the sulfolane synthesis, application of sulfolane as an extractive solvent due to its ‘unique’ physicochemical properties as well as the potential of sulfolane to cause equipment corrosion and subsequent spills. The potential risk for groundwater contamination, danger for human health and ways of sulfolane biodegradation were briefly reviewed as well. Interestingly, the analysis performed on data stored in the Reaxys database revealed an alternating tendency of waxing and waning interest in sulfolane during the space of the last fifty years. Moreover, the primary goal of the presented case study was to verify applicability of industrial, multi-electrochemical technique for reliable detection of corrosion in low conductive process fluids. Several aspects of corrosion measurement including the impact of process parameters (temperature) and impurities (oxygen and chlorides) on stainless steel corrosion in pure sulfolane were investigated briefly

Electrochemical corrosion monitoring in low conductive fluid : pilot-scale study on sulfolane corrosion potential

Solvents are a group of chemical compounds that are widely used in organic synthesis. Taking into account the chemical nature, solvents are divided into protic and aprotic ones. An attractive alternative to commonly used industrial extractive liquids is an anthropogenic, organosulfur medium—sulfolane. Sulfolane is a five-membered heterocyclic sulfur–organic compound from the group of sulfones (R-SO2-R’, where R/R’ is alkyl, alkenyl, or aryl), which contains an apolar hydrocarbon backbone and a polar functional group. It is a selective solvent in the liquid–liquid and liquid–vapor extraction processes used for the removal of close-boiling alkanes from cycloalkanes or for the separation of compounds with different degrees of saturation and polarity in the extractive rectification of arenes from non-aromatic saturated hydrocarbon mixtures. In standard conditions sulfolane is not an aggressive solvent for steel, but at higher temperature (170–180 °C) and oxygen availability, it may be decomposed and subsequently some corrosive (by-)products can be formed. The primary purpose of the presented pilot-case examination was to verify applicability of the industrial, multi-electrochemical technique for reliable detection of the corrosion processes in low conductive fluids

Influence of physical activity on cancer development, treatment and prophylaxis

Activation of the growth factors pathways is involved in cell growth and proliferation and is associated with carcinogenesis. Many studies have shown an increase in blood growth factors concentrations after training. On the other hand, numerous organisations recommend physical activity in cancer therapy and prophylaxis. This two phenomena may actually cause confusion. The aim of this paper was to present findings on the significance of physical activity in course of neoplastic disease and dispel doubts concerning its role in cancer treatment

Catchment management influence on the magnitude of the total solids load conveyed by the stormwater sewer system – a comparative case study

The aim of the investigations was to make a comparative analysis of TSS concentration and variability in TSS loads as well as to analyse first flush phenomena. That issue is related to the characteristics of two urban catchments located in the city of Kielce. The runoff events observed in the period of investigations (years 2009 – 2016) showed a great diversity. The analyses performed for the study revealed substantial differences in the values of TSS concentration and loads in stormwater from the catchments of concern. The highest TSS concentration in the stormwater for the catchment located at the city outskirts was 252 mg.dm-3, whereas for the catchment in the city centre that value was almost 30 – fold higher and amounted to 7432 mg.dm-3. The analysis of the runoff first flush with respect to the mass of total solids in individual rainfall events showed substantial differences in the course of the process depending on the type of catchment management. In the densely built-up area, the initial 25% and 30% of the volume of runoff transported 25-41% and 30-48% of the solids mass, respectively. In the other catchment, with low and sparsely located buildings, the maximum values of TSS mass were considerably higher and amounted to 22-83% and 28-87%

Soybean Seedlings Enriched with Iron and Magnesium - Impact on Germination, Growth and Antioxidant Properties

Abstract Iron (Fe) and magnesium (Mg) deficiency in human diets is a widespread problem observed in various regions of the world. Insufficient Fe uptake results in the development of iron dependent anaemia and depressed physical and intellectual performance. In turn Mg deficiency is associated with alterations in neuromuscular and cardiovascular systems. An emerging alternative to traditional supplementation of these elements in the form of pills, liquids or effervescent tablets, is introduction of fortified food products. In present study we show that preincubation of soybean seeds in Fe and Mg solutions leads to elevated content of these elements in the seedlings. Importantly the pretreatment did not affect germination rate, seedlings growth or, with an exception of Fe supplementation at highest concentration, antioxidant capacity. The obtained results indicate that preincubation of seeds in Fe and Mg solutions may be a promising method of obtaining enriched soybean sprouts

THE RELATION BETWEEN EMOTIONAL INTELLIGENCE AND INTERNET ADDICTION IN KATOWICE HIGH SCHOOL STUDENTS

Backgroud: Emotional intelligence (EI) is described as the capacity to be aware of, control, and express one\u27s emotions, and to handle interpersonal relationships judiciously and empathetically. It is considered as one of the most important predictors of success, quality of relationships, and overall happiness. Dynamically changing environment of the youth and young adults in recent years may influence their EI development, affecting their lives significantly. The purpose of this study was to analyse the way how the Internet is used by high school students, to determine the amount of time they spend on the Internet, identify the level of EI and to explore if there is any correlation between those factors. Subjects and methods: 1450 high school students from Katowice, at the age from 18 to 21 years took part in an anonymous survey consisting of three parts: The Trait Emotional Intelligence Questionnaire – Short Form (TEIQue-SF), Internet Addiction Test and authorial test giving information about the way of spending time online. The questionnaires were collected from May 2018 to January 2019. Results: 1.03% of the respondents fulfilled the Internet addiction criteria. Students at risk for addiction (33.5%) turned out to be a larger group. A statistically significant correlation between TEIQue-SF and Internet Addiction Test score (P<0.0001, r=-0.3308) was observed. Another significant correlation was found between TEIQue-SF score and amount of time spend on the Internet (p<0.0001, r=-0.162). Conclusion: A significant part of high school students used Internet excessively. Such behaviours were positively correlated with lower EI test results

New phosphorus analogs of bevirimat: synthesis, evaluation of anti-HIV-1 activity and molecular docking study

Since the beginning of the human immunodeficiency virus (HIV) epidemic, many groups of drugs characterized by diverse mechanisms of action have been developed, which can suppress HIV viremia. 3-O-(3′,3′-Dimethylsuccinyl) betulinic acid, known as bevirimat (BVM), was the first compound in the class of HIV maturation inhibitors. In the present work, phosphate and phosphonate derivatives of 3-carboxyacylbetulinic acid were synthesized and evaluated for anti-HIV-1 activity. In vitro studies showed that 30-diethylphosphonate analog of BVM (compound 14a) has comparable effects to BVM (half maximal inhibitory concentrations (IC50) equal to 0.02 μM and 0.03 μM, respectively) and is also more selective (selectivity indices: 3450 and 967, respectively). To investigate the possible mechanism of antiviral effect of 14a, molecular docking was carried out on the C-terminal domain (CTD) of HIV-1 capsid (CA)–spacer peptide 1 (SP1) fragment of Gag protein, designated as CTD-SP1, which was described as a molecular target for maturation inhibitors. Compared with interactions between BVM and the protein, an increased number of strong interactions between ligand 14a and protein, generated by the phosphonate group, was observed