17 research outputs found

    Changing cause of death profile in Morocco : The impact of child-survival programmes

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    This study was carried out to evaluate the trends in cause-specific mortality and the impact of child-survival programmes in Morocco. Two national surveys on causes and circumstances of child deaths were conducted in Morocco in 1988 and 1998 (ECCD-1 and ECCD-2 respectively). These surveys were based on a representative sample of deaths of children aged less than five years (432 and 866 respectively). Causes of death were assessed by verbal autopsy and were validated on a subsample of 94 cases. Data on causes of deaths were matched with death rates from demographic surveys (Enquete Nationale Demographique a Passages Repetes and Demographic and Health Survey) to compute cause-specific death rates. Morocco underwent a dramatic mortality decline since independence, and the decline in mortality among children aged less than five years was particularly rapid over the 1988-1997 period, at an average rate of -6% a year, and faster for children (aged 1-4 year(s)) than for infants. The decline in mortality varied markedly by causes of death and was most pronounced for causes due to vaccine-preventable diseases, such as neonatal tetanus, measles, whooping cough, tuberculosis, for diarrhoeal diseases and malnutrition, and for selected infectious diseases. However, mortality due to acute lower respiratory infection (ALRI) outside the neonatal period did not change significantly as was the case for some neonatal conditions (birth trauma and prematurity) and for accidents. The decline in cause-specific mortality could be attributed to the success of public-health programmes: the Expanded Programme on Immunization, the management of diarrhoeal diseases and malnutrition, and the use of antibiotics for selected infectious diseases. It is likely that improvements in living conditions, child-feeding practices, hygiene, and sanitation also contributed to the decline in mortality, although these could not explain the magnitude of the changes for target diseases. In contrast, the ALRI programme, which started after 1997, could not have any effect yet, and conditions of delivery and care of the newborn improved only marginally over the study period

    Parabolic inequalities in L1 as limits of renormalized equations

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    The paper deals with the existence of solutions of some parabolic bilateral problems approximated by the renormalized solutions of some parabolic equations

    Selection effects of source of contraceptive supply in an analysis of discontinuation of contraception: multilevel modelling when random effects are correlated with an explanatory variable

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    Conventional multilevel models assume that the explanatory variables are uncorrelated with the random effects. In some situations, this assumption may be invalid. One such example is the evaluation of a health or social programme that is non-randomly placed and/or in which participation is voluntary. In this case, there may be unobserved factors influencing the placement of the programme and the decision to participate that are correlated with the unobserved factors that influence the outcome of interest. The paper presents an application of a multiprocess multilevel model to assess the difference in rates of discontinuation of contraception between private and Government family planning providers, while accounting for the possibility that there may be unobserved individual and community level factors that influence both a couple's choice of provider and their probability of discontinuation. Copyright 2003 Royal Statistical Society.

    Selection effects of source of contraceptive supply in an analysis of discontinuation of contraception: multilevel modelling when random effects are correlated with an explanatory variable

    No full text
    Conventional multilevel models assume that the explanatory variables are uncorrelated with the random effects. In some situations, this assumption may be invalid. One such example is the evaluation of a health or social programme that is non-randomly placed and/or in which participation is voluntary. In this case, there may be unobserved factors influencing the placement of the programme and the decision to participate that are correlated with the unobserved factors that influence the outcome of interest. The paper presents an application of a multiprocess multilevel model to assess the difference in rates of discontinuation of contraception between private and Government family planning providers, while accounting for the possibility that there may be unobserved individual and community level factors that influence both a couple's choice of provider and their probability of discontinuation

    Pyrano-isoflavans from <i>Glycyrrhiza uralensis</i> with Antibacterial Activity against <i>Streptococcus mutans</i> and <i>Porphyromonas gingivalis</i>

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    Continuing investigation of fractions from a supercritical fluid extract of Chinese licorice (<i>Glycyrrhiza uralensis</i>) roots has led to the isolation of 12 phenolic compounds, of which seven were described previously from this extract. In addition to these seven metabolites, four known components, 1-methoxyerythrabyssin II (<b>4</b>), 6,8-diprenylgenistein, gancaonin G (<b>5</b>), and isoglycyrol (<b>6</b>), and one new isoflavan, licorisoflavan C (<b>7</b>), were characterized from this material for the first time. Treatment of licoricidin (<b>1</b>) with palladium chloride afforded larger amounts of <b>7</b> and also yielded two new isoflavans, licorisoflavan D (<b>8</b>), which was subsequently detected in the licorice extract, and licorisoflavan E (<b>9</b>). Compounds <b>1</b>–<b>9</b> were evaluated for their antibacterial activities against the cariogenic <i>Streptococcus mutans</i> and the periodontopathogenic <i>Porphyromonas gingivalis</i>. Licoricidin (<b>1</b>), licorisoflavan A (<b>2</b>), and <b>7</b>–<b>9</b> showed antibacterial activity against <i>P. gingivalis</i> (MICs of 1.56–12.5 μg/mL). The most potent activity against <i>S. mutans</i> was obtained with <b>7</b> (MIC of 6.25 μg/mL), followed by <b>1</b> and <b>9</b> (MIC of 12.5 μg/mL). This study provides further evidence for the therapeutic potential of licorice extracts for the treatment and prevention of oral infections
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