Isolated muscle tuberculosis: exceptional location

The authors report the exceptional case of isolated muscular tuberculosis affecting the anterior compartment of the right thigh in a 38-year-old man. The diagnosis was based on histology and GeneXpert. The subject received a surgical treatment followed by medical treatment for 6 months. The GeneXpert test has proved to be useful in the diagnosis of muscular tuberculosis. We have not found in the literature the use of GeneXpert in this type of localization of tuberculosis whose diagnostic is not always easy. Through the study of this case and a review of the literature, the authors review the pathogenesis of this particular affection as well as the diagnostic and therapeutic modalities.

Effects of Slag-Based Fertilizer to Mitigate Salinity Stress on Greenhouse Durum Wheat (Triticum Durum Desf.) Cultivars

For a modern agricultural, the search for sustainable practices to increase productivity is fundamental. Steel slag have been studied for their potential use in agriculture. These substances present a great possibility of agricultural applications since they are rich in nutrients, which enhance plant uptake. In this regard, the effect of steel slag based-fertilizer was investigated in the greenhouse durum wheat cultivation in pots under salt-stress conditions. Two slag doses: 10 g slag/ kg soil (D1) and 20 g slag/ kg soil (D2) were evaluated under no salt-stress (0 mM NaCl) and salt-stress conditions (100 mM NaCl) for salinity stress mitigation. Morpho-physiological and biochemical parameters of wheat were measured and compared to the different treatments. Wheat exposure to salinity decreased its biomass, stomatal conductance, efficiency of photosystem II, protein content and increased total soluble sugars, hydrogen peroxide (H2O2) and malondialdehyde (MDA) contents. Amended plants with 10 g slag/ kg soil (D1), led to a significant improve in biomass with an increase of shoot and root dry weights (133% and 400% respectively), stomatal conductance (22 %), soluble sugars (14 %) and protein content (158%) under salinity conditions as compared to the control treatment 0 g slag/ kg soil (C), indicating a positive influence on durum wheat plants. However, soil enrichment with 20 g slag/ kg soil (D2) decreased plant growth parameters and presented the highest levels of H2O2 and MDA contents compared to the control and treatment D1 after three months of cultivation under salt-stress. This study supports the hypothesis of the application of slag at lower dose improve productivity of durum wheat and mitigate salinity stress

Effects of Slag Applications and Salinity Stress on Greenhouse Durum Wheat (Triticum durum Desf.) Plants

The search for sustainable practices to increase productivity is a fundamental need in current agriculture. Steel slag has been studied for its potential use in agriculture. These substances present a great ability of agricultural applications since they are rich in nutrients. The effect of steel slag-based fertilizer was investigated on greenhouse durum wheat cultivar under salt-stress conditions. Two doses of slag: 10 g slag/ kg soil (D1) and 20 g slag/ kg soil (D2) were evaluated under no salt-stress (0 mM NaCl) and salt-stress conditions (100 mM NaCl) for salinity stress mitigation. Morpho-physiological and biochemical parameters of wheat were measured and compared to the different treatments. Exposure of wheat to salinity decreased its biomass, stomatal conductance, efficiency of photosystem II, and protein content, but it increased total soluble sugars, hydrogen peroxide (H2O2), and malondialdehyde (MDA) contents. Amended plants with 10 g slag/ kg soil (D1) led to a significant improvement in biomass with an increase of shoot and root dry weights (133% and 400% respectively), stomatal conductance (22 %), soluble sugars (14 %), and protein content (158%) under saline conditions compared to the control treatment with 0 g slag/ kg soil (C), thus indicating a positive influence on durum wheat plants. Soil enrichment with 20 g slag/kg soil (D2) decreased plant growth parameters and presented the highest levels of H2O2 and MDA contents compared to the control and treatment (D1) after three months of cultivation under salt stress. This study supports the hypothesis of the application of slag at lower dose, which improves productivity of durum wheat and mitigate salinity stress

Effects of Slag-Based Fertilizer to Mitigate Salinity Stress on Greenhouse Durum Wheat (Triticum Durum Desf.) Cultivars

For a modern agricultural, the search for sustainable practices to increase productivity is fundamental. Steel slag have been studied for their potential use in agriculture. These substances present a great possibility of agricultural applications since they are rich in nutrients, which enhance plant uptake. In this regard, the effect of steel slag based-fertilizer was investigated in the greenhouse durum wheat cultivation in pots under salt-stress conditions. Two slag doses: 10 g slag/ kg soil (D1) and 20 g slag/ kg soil (D2) were evaluated under no salt-stress (0 mM NaCl) and salt-stress conditions (100 mM NaCl) for salinity stress mitigation. Morpho-physiological and biochemical parameters of wheat were measured and compared to the different treatments. Wheat exposure to salinity decreased its biomass, stomatal conductance, efficiency of photosystem II, protein content and increased total soluble sugars, hydrogen peroxide (H2O2) and malondialdehyde (MDA) contents. Amended plants with 10 g slag/ kg soil (D1), led to a significant improve in biomass with an increase of shoot and root dry weights (133% and 400% respectively), stomatal conductance (22 %), soluble sugars (14 %) and protein content (158%) under salinity conditions as compared to the control treatment 0 g slag/ kg soil (C), indicating a positive influence on durum wheat plants. However, soil enrichment with 20 g slag/ kg soil (D2) decreased plant growth parameters and presented the highest levels of H2O2 and MDA contents compared to the control and treatment D1 after three months of cultivation under salt-stress. This study supports the hypothesis of the application of slag at lower dose improve productivity of durum wheat and mitigate salinity stress

Vagus Nerve Acupucture-Like Transcutanious Electrical Nerve Stimulation on Immunity After Liver Resection

Objective: To find out the therapeutic impact of acupuncture like-transcutaneous electrical nerve stimulation of vagus nerve on immunity after liver resection. Methods This was a single-blind randomized controlled trial. A total of sixty individuals who had undergone liver resection at the National Liver Institute Hospital at Menofiea University were randomly divided into two groups: study group A (n=30) and control group B (n=30). The study group had vagus nerve stimulation with acupuncture like-TENS parameters include low-frequency (2–10Hz), pulse width (100–40

Nutrition Situation Analysis in the UAE: A Review Study

This review study aimed to assess the nutrition situation in the UAE using published data from 2010 to 2022. It highlights the gaps and challenges that prevail in addressing the nutrition-related problems in the UAE and the opportunities that have been overlooked. The available literature indicates that the UAE is burdened with more than one form of nutrition-related problems, including being underweight, being overweight, obesity, micronutrient deficiencies, and nutrition-related chronic diseases. It is clear that data on micronutrient deficiencies, protein-energy malnutrition, obesity, diabetes, and other nutrition-related diseases among the UAE population are extremely scarce. The UAE has a high prevalence of obesity and diabetes; however, limited studies have been conducted to document this nutritional phenomenon. Few examples of published data are available assessing the burden of stunting, wasting, and being underweight among children under five years of age. Despite the importance of protein-energy malnutrition, no recent publications analyze its prevalence within the UAE population. Therefore, future studies must be conducted, focusing on malnutrition. Based on the literature, and bearing in mind the magnitude of the health issues due to the UAE population\u27s nutrition negligence, there is an urgent need to assess the population\u27s nutrient behaviors, to aid policy decision-makers in developing and implementing effective health policies and strategies

MicroRNAs are deeply linked to the emergence of the complex octopus brain

Soft-bodied cephalopods such as octopuses are exceptionally intelligent invertebrates with a highly complex nervous system that evolved independently from vertebrates. Because of elevated RNA editing in their nervous tissues, we hypothesized that RNA regulation may play a major role in the cognitive success of this group. We thus profiled messenger RNAs and small RNAs in three cephalopod species including 18 tissues of the Octopus vulgaris. We show that the major RNA innovation of soft-bodied cephalopods is an expansion of the microRNA (miRNA) gene repertoire. These evolutionarily novel miRNAs were primarily expressed in adult neuronal tissues and during the development and had conserved and thus likely functional target sites. The only comparable miRNA expansions happened, notably, in vertebrates. Thus, we propose that miRNAs are intimately linked to the evolution of complex animal brains

Cell type atlas and lineage tree reconstruction of whole adult animals by single-cell transcriptomics

Flatworms of the species Schmidtea mediterranea are immortal –adult animals contain a large pool of pluripotent stem cells that continuously differentiate to all adult cell types. Therefore, single-cell transcriptome profiling of adult animals should reveal mature and progenitor cells. Here, by combining perturbation experiments, gene expression analysis, a computational method that predicts future cell states from the transcriptional changes, and a novel lineage reconstruction method, we placed all major cell types onto a single lineage tree that connects all cells to a single stem cell compartment. We characterize gene expression changes during differentiation and discover cell types important for regeneration. Our results demonstrate the importance of single-cell transcriptome analysis for mapping and reconstructing fundamental processes of developmental and regenerative biology at unprecedented resolution

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely