Non-ketotic hyperglycaemia presenting as epilepsia partialis continua

AbstractEpilepsia partialis continua (EPC) is a rare epileptic syndrome, observed in various cortical lesions and also in metabolic disorders. We report the case of a 57-year-old patient with EPC as the first manifestation of hyperosmolar non-ketotic hyperglycaemia (NKH) of diabetes mellitus. Computed tomography (CT) and magnetic resonance imaging (MRI) were normal. Initial laboratory data revealing serum glucose 1540mg/dl, and serum osmolality 391mOsm/l confirmed the diagnosis. Electroencephalography (EEG) showed ictal discharges in the ipsilateral hemisphere during focal seizures. Seizures are resistant to anticonvulsant treatment and respond best to insulin and rehydration. Focal motor seizures or EPC are commonly a symptom of NKH in the elderly patients. We recommend that in such cases a metabolic disorder such as diabetes mellitus be ruled out

Characteristic Mode Analysis of Unit Cells of Metal-Only Infinite Arrays

Characteristic mode analysis of metal only unit cells of periodic structures is performed using Method of Moments based formulation. Ewald's transformation is incorporated for a fast and cost efficient solution and the advantages over spatial Green's function are discussed. The influence of the unit cell size on the characteristic modes is demonstrated. Various metal-only reflectarray elements are compared and their radiation characteristics are interpreted using the theory of characteristic modes. It is shown that characteristic modes of the unit cell can help us to understand the radiation and scattering behavior of the unit cell and this physical insight can be used in periodic array unit cell design

A new software development for Fuzzy Multicriteria decision‐making

In this paper, software for Fuzzy Multiple Criteria Decision Making (FMCDM) problems has been developed and tested on two real problems. FMCDM methods are widely used when imprecise data or linguistic variables exist in the problem. Using FMCDM methods may help improve decision‐making problems and lead to more accurate models. Although these methods are more involved in terms of computing due to fuzzy calculations in MCDM algorithms, fuzziness offers advantages over classical algorithms. Thus appropriate software is of great importance in applying FMCDM methods. The major aim of this study is to develop software and to test it on two real military problems which are solved by an ideal points algorithm and an outranking method. The results and outputs are discussed with sensitivity analyses. Santrauka Aprašomos programos, skirtos daugiakriteriniam sprendimų priėmimui esant neapibrėžtumams, kūrimas ir jos pritaikymas sprendžiant dvi realias problemas. Neapibrėžtųjų aibių daugiakriteriniai metodai plačiai taikomi, kai esama netikslių duomenų arba lingvistinių kintamųjų. Taikant šiuos metodus galima lengviau išspręsti sprendimo priėmimo problemas, sudaryti tikslesnius modelius. Nors tokiu atveju reikia daugiau skaičiavimų siekiant taikyti neapibrėžtąsias aibes daugiakriteriniuose sprendimų priėmimo algoritmuose, tačiau galimybė įvertinti neapibrėžtumus suteikia pranašumų, palyginti su klasikiniais metodais. Taigi neapibrėžtųjų aibių daugiakriteriniams metodams labai svarbu tinkama programinė įranga. Svarbiausias šio tyrimo tikslas – sukurti programinę įrangą ir testuoti ją sprendžiant dvi tikras karines problemas – idealiųjų taškų agoritmą ir rangavimų metodą. Rezultatai aptarti atlikus jautrumo analizę. First published online: 21 Oct 2010 Reikšminiai žodžiai: neapibrėžtųjų aibių daugiakriterinis sprendimų priėmimas (NADSP), idealieji taškai, rangavimas, programinė įranga

Could cellular proliferation be a predictive index for the relapse of nasal polyposis and down-regulated by nasal steroid treatment?

The aim of this article is to identify the cellular mitotic activity using Ki-67 monoclonal antibody for predicting relapses of nasal polyposis after surgery. A prospective study was conducted at Kartal Training and Research Hospital Otolaryngology Department between January 2006 and September 2008. Nasal polyps were obtained from all patients and pathological materials were analyzed for the Ki-67 staining using immunohistochemistry. Patients were followed after surgery for 12 months for relapse. There was no statistically significant difference between recurrent and nonrecurrent polyps. Polyp recurrence has a multifactorial origin. Ki-67 index alone does not provide sufficient information about polyp recurrence before the operation. © 2012 Association of Otolaryngologists of India

COVID-19 pandemi döneminde acil servise yapılan tekrarlayan başvuruların değerlendirilmesi

Objective: Coronavirus disease-2019 has resulted in changes in healthcare and management services. One of these changes is related to in patient presentation to emergency departments (ED). This study aimed to investigate the rate of recurrent presentations to an ED during the pandemic period compared to the pre-pandemic period. Materials and Methods: Patients that presented to the ED of a tertiary hospital again within 72 hours of their first visit were screened from the hospital information management system for the pre pandemic (June 1-November 30, 2019) and pandemic (June 1-November 30, 2020) periods. So, hospitalization rates were compared between the two periods. Results: In the pre-pandemic period, the number of ED registrations was 67,414, of which 3,463 belonged to recurrent presentations, while in the pandemic period, these numbers were determined as 43,636 and 2,238, respectively. The rate of admission to any hospital ward (n=521, 16.4%) or the intensive care unit (n=56, 1.8%) nearly doubled during the pandemic. Six of these patients died in the ED in the pandemic period, while no death was observed in the pre-pandemic period. Conclusion: Although there was a decrease in the number of both hospital and ED presentations during the pandemic, an increase was observed in the number of patients with recurrent presentations to the ED. As a result of this patient group postponing visits to the hospital for their acute problems due to the fear of being infected, their need for hospitalization and intensive care follow-up increased.Amaç: Koronavirüs hastalığı-2019 (COVID-19) sağlık bakım ve yönetim hizmetlerinde değişikliklere neden oldu. Bu değişikliklerden biri de acil servis hasta başvurularında yaşandı. Bu çalışmada pandemi döneminde acil servislerde tekrarlayan başvuru oranlarının araştırılması amaçlanmıştır. Gereç ve Yöntemler: Pandemi öncesi dönem (1 Haziran-30 Kasım 2019) ile pandemi döneminde (1 Haziran -30 Kasım 2020) 3. basamak bir hastanenin acil servisine ilk başvuru sonrası 72 saat içerisinde tekrar başvuruda bulunan hastalar hastane bilgi yönetimi sistemi üzerinden taranmıştır. Hastane ve acil servis başvuru sayıları, demografik özellikleri ve hastaneye yatış oranları her iki dönem açısından karşılaştırılmıştır. Bulgular: Pandemi öncesi dönemde acil servis kayıt sayısı 67.414 olup bu hastalar içerisinde 3.463’ü tekrarlayan başvuruyken, pandemi döneminde kayıt sayısı 43.636 olup bunların 2.238’i tekrarlayan başvuruda bulunmuştur. Dönemler arasında istatistiksel olarak yaş ve cinsiyet açısından farklılık tespit edilmemiştir (p=0,143). Ancak tekrar başvuruda bulunan hastalar arasında yatarak takip ve tedavi edilmesi gereken hasta grubunun yaşı pandemi döneminde daha yüksekti. Pandemi döneminde herhangi bir kliniğe (n=521, %16,4) veya yoğun bakım ünitesine yatış (n=56, %1,8) oranlarında yaklaşık iki kat artış oldu. Bu hastalardan 6’sı pandemi döneminde acil serviste ölümle sonlanıma sahipken normal dönemde ölümle sonlanım görülmemiştir. Sonuç: Pandemi döneminde hem genel hastane hem de acil servis başvuru sayılarında azalma olmasına rağmen acil servise tekrarlayan başvuruda bulunan hasta sayısında artış olduğu tespit edildi. Bu hasta grubunun enfekte olma korkusu nedeniyle akut gelişen problemlerini ertelemesi karşısında herhangi bir kliniğe yatış ve yoğun bakım ünitesinde takip edilme ihtiyaçlarının artığı görüldü

HALKLA İLİŞKİLER LİSANS ÖĞRENCİLERİNİN TOPLUMSAL CİNSİYET ROLLERİNE YÖNELİK TUTUMLARI

Bu çalışmada Uşak Üniversitesi İletişim Fakültesi Halkla İlişkiler ve Reklamcılık Bölümü birinci ve dördüncü sınıfında okuyan öğrencilerde toplumsal cinsiyet algısına yönelik tutumların saptanması ve toplumsal cinsiyet rollerine yönelik tutumu yordayan değişkenlerin araştırılması amaçlanmıştır. Çalışmanın amacını gerçekleştirmek için 146 halkla ilişkiler lisans öğrencisinden yapılandırılmış soru formu ile veri toplanmıştır. Halkla ilişkiler öğrencilerinin toplumsal cinsiyet rollerine yönelik tutumlarını belirlemek için ortalama puanlar; cinsiyete ve sınıfa göre farklılıkları tespit etmek için ise bağımsız örneklem t-testi; tutumları oluşturan yordayıcıları belirlemek için regresyon analizi kullanılmıştır. Elde edilen sonuçlar, halkla ilişkiler öğrencilerinin genel olarak toplumsal cinsiyet rollerine ilişkin eşitlikçi bir tutum içerisinde olduğunu göstermiştir. Sınıflar arasındaki farklar toplumsal cinsiyet rollerine yönelik tutumların eğitimle eşitlikçi bir tutuma değiştiğini ortaya koymuştur. Tutumların oluşumunda en önemli yordayıcının cinsiyet olduğu belirlenmiştir. Halkla ilişkiler eğitim müfredatı toplumsal cinsiyet eşitliği yönünde tutumlar oluşturacak biçimde yapılandırılmalıdır

Türkiye ekonomisi: Kendi krizlerinden küresel finans krizine

2007 yılı ortalarında ABD’den yükselen istikrarsızlık dalgası, 2008 Kasımından itibaren, liberal kapitalist sistemin önemli bir bölümünü tesiri altına alan ağır bir finans krizine dönüşmüştür. Bir bütün olarak dünya ekonomisinde büyüme yavaşlarken enflasyon ve işsizlik artmıştır. 2000 yılı sonunda ve 2001 yılı başında peş peşe yaşadığı kendi finansal krizlerinin ardından yeni bir büyüme dalgası yakalayan Türkiye ekonomisinin, küresel finans krizini olabilecek en az hasarla atlattığı söylenebilir. Keza 2010 yılından itibaren kriz öncesi büyüme performansının yakalandığı görülmektedir. Ne var ki işsizlik sorunu ehemmiyetini korumaktadır; istihdam yaratmayan bir büyüme söz konusu olmaktadır. Diğer bir sorun, büyüme sürecinde cari işlemler açı- ğının artıyor olmasıdır

The evaluation of risk factors related to reduced bone mineral density in young people living with HIV

Background: Low bone mineral density (BMD) is one of the comorbidities that develop in people living with HIV (PLWHIV). Objective: This study was conducted to review the frequency and risk factors of reduced BMD according to age in HIV-infected patients in Turkey. Material and Method: This retrospective cohort study included HIV-infected patients aged 18-50. Bone density was analysed using dual-energy X-ray absorptiometry (DXA) according to the Z-score in three different regions including the lumbar, total-hip and femoral-neck. Results: The study included 224 PLWHIV with a mean age of 35.84-7.54, and 59.8% were ART naive. Of the patients, 40.6% had lower BMD than expected at least in one of the three examined regions including the lumbar, total hip and femoral neck. The low BMD ratios were found respectively as 11.6%, 11.6% and 28.6% in the femoral neck, total hip and lumbar regions. According to the logistic regression model, a high body mass index (p=0.003) and HIV-RNA level of ≥100.000IU/ml during the diagnosis in the ART-naive group (p=0.008) were associated with reduced bone demineralization. The low BMD frequency was high in the group that received ART for <24 months (p=0.001). Conclusion: Performing bone demineralization screening in the naive and young patient group, independently from ART status prior to making the diagnosis of HIV is important for organizing the bone health improvement methods. Keywords: HIV infection; bone density; antiretroviral therapy

ANXIETY AND DEPRESSION AMONG PEOPLE LIVING WITH HIV DURING THE COVID-19 PANDEMIC: A FACE-TO-FACE SURVEY FROM TURKEY

Background: During the COVID-19 pandemic, there have been some difficulties in the routine care of people living with HIV (PLWH). Subjects and methods: We aimed to evaluate the impact of COVID-19 on mental health of PLWH and their use of health services. This study was conducted using the face-to-face interview method in the outpatient clinic of a university hospital, between 01.09.2020 and 30.11.2020. Hospital Anxiety and Depression Scale and survey instrument designed by the researchers investigating socio-demographic data and access to health services were used. Results: The study included 217 patients, 91.7% (n=199) of whom were male. All of the patients were postponed their hospital appointments, 60.8% were concerned about not being able to contact their physician and 53% had concerned about being stigmatized if they went to the hospital. Of the participants, 27.6% had depression, 12.9% had anxiety and 8.3% had both depression and anxiety. Low income, job loss, and fear of being stigmatized were associated with depression and anxiety. Lower level of education, discontinuation of medications and lack of opportunity to work remotely were associated with depression, while history of psychiatric illness, worry about not being able to contact their physician and cessation of antiretroviral therapy were associated with higher anxiety levels. Conclusion: It is important to develop strategies ensuring the continuity of care for PWLH and identify and support those with a higher mental health impact

Value of Caffeic Acid Phenethyl Ester Pretreatment in Experimental Sepsis Model in Rats

Background and Aim. The aim of this study was to determine the actions of caffeic acid phenethyl ester (CAPE) on the changes of endothelin-1 (ET-1) level, tumor necrosis factor- (TNF-) alpha, and oxidative stress parameters such as superoxide dismutase (SOD) activities and malondialdehyde (MDA) levels in experimental sepsis model in rats. Materials and Methods. Twenty-four rats were randomly divided into three experimental groups: sham (group 1), sepsis (group 2), and sepsis + CAPE (group 3), n = 8 each. CAPE was administered (10 mu mol/kg) intraperitoneally to group 3 before sepsis induction. Serum ET-1, serum TNF-alpha, tissue SOD activity, and tissue MDA levels were measured in all groups. Results. Pretreatment with CAPE decreased ET-1, TNFalpha, and MDA levels in sepsis induced rats. Additionally SOD activities were higher in rats pretreated with CAPE after sepsis induction. Conclusion. Our results demonstrate that CAPE may have a beneficial effect on ET and TNF-alpha levels and oxidative stress parameters induced by sepsis in experimental rat models. Therefore treatment with CAPE can be used to avoid devastating effects of sepsis