Modélisation de la propagation de l'impulsion électrique dans un modèle de tissu cardiaque tridimensionnel

Excitation cardiaque normale -- Arythmie cardiaque -- Historique de la modélisation de la propagation -- Modélisation de la propagation -- Modélisation de la réentrée -- Méthodes -- Modèle membranaire -- Modèle de propagation -- Solution générale -- Algorithme de solution -- Simulation de la propagation -- Simulation de la réentrée dans un modèle de tissu bidimensionnel -- Simulation de la réentrée dans un modèle de tissu tridimensionnel

Streptococcus Intermedius Brain and Diverticular Abscesses After Dental Manipulation: A Case Report.

A brain abscess is defined as a focal intracerebral infection consisting of an encapsulated collection of pus, which can be a life-threatening complication of infections, trauma, or surgery. While immunocompromised patients can have a wide array of causative organisms, bacterial species represent the most common etiology in immunocompetent individuals. The incidence of brain abscesses ranges from 0.4 to 0.9 per 100,000, with a high predisposition among immunocompromised patients and in those with disruption of the blood-brain barrier. The most common causative organisms found were Streptococcus species, particularly S. viridians and S. pneumonia, Enterococcus, and Staphylococcus species, mainly S. aurieus and S. epidermidis. Microorganism can invade the brain through different mechanisms, either directly by contiguous spread and odontogenic infections, which usually cause a single brain abscess, or indirectly through hematogenous spread which can cause multiple brain abscesses. Both surgical and conservative dental procedures contribute to hematogenous spreading of oral microorganisms. Although most of those organisms are eliminated shortly after they gain access to the bloodstream, some can persist and contribute to the pathogenesis of abscesses in the appropriate environment. Odontogenic origins are rarely implicated in the formation of brain abscesses, and oral foci comprise approximately 5% of identified cases. We report a case of brain and diverticular abscesses due to S. intermidius occurring two months after dental extraction. This case highlights the fact that even usual dental workup can result in the development of bacteremia and disseminated abscesses including but not restricted to the brain. Consequently, in addition to identifying the possible source of bacteremia with an extensive history and physical exam, the diagnosis of Streptococcus milleri organisms should prompt the physicians to screen for sites of possible metastatic infection spread

Assessing actual evapotranspiration in irrigation districts using Landsat TM images and SEBAL model: Potential uses for irrigation monitoring

Satellite imagery allows the observation of large land stretches and the acquisition of worthwhile information that can be used efficaciously in agro-hydrologic systems. On the other hand, remotely sensed data coupled with energy balance models represent reliable tools to estimate actual evapotranspiration (ET). Objective of the research was to propose a methodology to estimate ET by using Landsat TM images and surface energy balance, thus allowing the monitoring of current irrigation practices and/or possible vegetation stress. The proposed methodology was applied in an irrigation district managed by \u201cConsorzio di Bonifica Agrigento 3\u201d, Castelvetrano, Sicily (Italy), in which water is distributed by a pressurized distribution network operating on-turn. Satellite information retrieved by a set of Landsat TM images allowed to implement the surface energy balance model (SEBAL) in order to map the spatial distribution of instantaneous ET over two main crops (olives and grapevines), during irrigation seasons (from May to September) 2009 and 2010. These instantaneous values were then up-scaled to daily values based on the hypothesis of self-preservation of evaporative fraction. Finally, daily acquisitions were used to derive ET within longer time intervals, by assuming the by assuming proportionality to temporal dynamics of the reference evapotranspiration (ET0) computed using standard ground meteo-data. With reference to the acquisition days, the comparison between SEBAL outputs and maximum daily crop evapotranspiration (ETc) estimated with the FAO 56 approach, showed notable stress levels for both the investigated crops, except for the images acquired in May, when significant rainfall occurred in both years. Moreover, measurements of eddy covariance fluxes collected by a tower located in the district within an olive orchard, evidenced the general reliability of daily ET retrieved by the model and consequently the validity of the self-preservation hypothesis applied to upscale instantaneous ET. Even if the applied methodology can be considered a valuable tool to monitor irrigation practices, the availability of cloud-free satellite images, as well as the temporal frequency of sensing, are critical issues for the proposed applications

Identifying and Addressing Soil Property Issues Affecting Roadside Vegetation Establishment

Attaining adequate vegetation cover along highways is important for NDOR to comply with EPA’s stormwater regulations. However, low plant cover is a common problem on shoulders (first 16 feet off the pavement) of many highways in Nebraska. The ultimate goal of this study is to identify cost-effective engineering solutions that assure adequate seed beds (i.e., soil conditions) for establishment of selected seeding mixtures. The objectives of this study are to (1) characterize the soil properties along roadsides where vegetation stands have not developed well, and (2) verify the effects of select soil property parameters on plant germination and establishment. Sampling occurred at multiple locations along the highways near Beaver Crossing and Sargent, NE. At each location, soil samples were collected from a transect of multiple landscape positions, perpendicular to the highway. The soil physical properties measured included cone index, sorptivity, and aggregate stability, while the soil chemical properties measured included EC, pH, organic matters, Na, and Ca. Results show that the soils near the edge of the highway pavement were highly compacted. Also, the soils had higher pH, lower organic matter, and higher salt levels than optimal conditions. In the subsequent greenhouse studies, a factorial design was used to test three factors: soil compaction (i.e., 1.5, 1.7, and 1.9 g cm-3 soil compaction levels as well as sand as control), timing of salt stress (2 pulses of salt treatment applied pre-germination and post-germination as well as no-salt control), and plant species (buffalo grass, tall fescue, and western wheat grass). Results from the greenhouse studies showed that the three plant species exhibited different germination and early survival responses to the soil compaction and salt treatments. Tall fescue is better suited for site re-vegetation especially if salt is present in the soil prior to germination. Statistical analysis show that salt treatment had the most impact on species performance. Finally the project recommends a few engineering remediation strategies for plant establishment. Creating microsites on compacted soil surfaces could potentially alleviate the soil compaction issue by creating local environmental conditions favorable to plant establishment at microsites. To remediate the high salt levels in soil, it is recommended to consider alternative de-icing agents and amend zeolites and organics in soil

RELIGION AND RELIGIOSITY: A WRONGFUL DISCOURSE OR NOT?

The study was set to investigate the nature and effects of religious violence along with the governments' role in combating such violence. The study also intended to reveal the causes of the increasingly growing impact of religious violence. The study has been based on the rationale that radicalism and fundamentalism empower religious violence. The study employed the meta-analysis research method whereby the researchers carried out the synthesis of results from existent studies to reach conclusions and inferences that could address the study questions. The findings of the study indicated that the religious violence often prospers due to the anger that the public holds for the marginalization that should be eradicated. Religion ignites the anger and turns it into  violence. The findings of the study showed that the economics of religion could be an approach based on the assumptions of stability, behavior, and preferences. The economic religious approach might be used rigorously to disseminate the fundamentals of religious violence. The portrayal of sects as militias and angry fanatics that are waging war against the enlightened and modern society made matters worse. Sects as a backbone of religious violence could flourish in communities that are different in culture and religion. It is recommended that governments adopt educational system and the strategy of organizing summits, dialogs, and commissions to give communities hope for a brighter future that could guarantee them and their posterity a happy, satisfying life in a setting where diversity and tolerance of all religions and cultures prevail.  Article visualizations

Large-scale lateral saturated soil hydraulic conductivity as a metric for the connectivity of subsurface flow paths at hillslope scale

Lateral saturated soil hydraulic conductivity, Ks,l, is the soil property governing subsurface water transfer in hillslopes, and the key parameter in many numerical models simulating hydrological processes at the hillslope and catchment scales. Likewise, the hydrological connectivity of the lateral flow paths plays a significant role in determining the rate of the subsurface flow at various spatial scales. This study investigates the relationship between Ks,l and hydrological connectivity at the hillslope spatial scale. Ks,l was determined by the subsurface flow rates intercepted by drains and water table depths observed in a well network. The hydrological connectivity was evaluated by the synchronicity among water table peaks, and between these and the peaks of the drained flow. Rainfall and soil moisture were used to investigate the influence of the transient hydrological soil condition on connectivity and Ks,l. As the synchronicity of the water table response between wells increased, the lag times between the peaks of water levels and those of the drained subsurface flow decreased. Moreover, the most synchronic water table rises determined the highest drainage rates. The relationships between Ks,l and water table depths were highly non-linear, with a sharp increase in the values for water table levels close to the soil surface. Estimated Ks,l values for the full saturated soil were in the order of thousands of mm h−1, suggesting the activation of macropores in the root zone. The Ks,l values determined at the peak of the drainage events were correlated with the indicators of synchronicity. The sum of cumulative rainfall and antecedent soil moisture was correlated with the connectivity indicators and Ks,l. We suggest that, for simulating realistic processes at the hillslope scale, the hydrological connectivity could be implicitly considered in hydrological modelling through an evaluation of Ks,l at the same spatial scale

Matter Fields in the Lagrangian Loop Representation: Scalar QED

We present the extension of the Lagrangian loop gauge invariant representation in such a way to include matter fields. The partition function of lattice compact U(1)-Higgs model is expressed as a sum over closed as much as open surfaces. We have simulated numerically the loop action equivalent to the Villain form of the action and mapped out the beta-gamma phase diagram of this model.Comment: 10 pages, LaTe

L-branes

The superembedding approach to $p$-branes is used to study a class of $p$-branes which have linear multiplets on the worldvolume. We refer to these branes as L-branes. Although linear multiplets are related to scalar multiplets (with 4 or 8 supersymmetries) by dualising one of the scalars of the latter to a $p$-form field strength, in many geometrical situations it is the linear multiplet version which arises naturally. Furthermore, in the case of 8 supersymmetries, the linear multiplet is off-shell in contrast to the scalar multiplet. The dynamics of the L-branes are obtained by using a systematic procedure for constructing the Green-Schwarz action from the superembedding formalism. This action has a Dirac-Born-Infeld type structure for the $p$-form. In addition, a set of equations of motion is postulated directly in superspace, and is shown to agree with the Green-Schwarz equations of motion.Comment: revised version, minor changes, references added, 22 pages, no figures, LaTe

A remote sensing and modeling integrated approach for constructing continuous time series of daily actual evapotranspiration

Satellite remote sensing-based surface energy balance (SEB) techniques have emerged as useful tools for quantifying spatialized actual evapotranspiration at various temporal and spatial scales. However, discontinuous data acquisitions and/or gaps in image acquisition due to cloud cover can limit the applicability of satellite remote sensing (RS) in agriculture water management where continuous time series of daily crop actual evapotranspiration (ETc act) are more valued. The aim of the research is to construct continuous time series of daily ETc act starting from temporal estimates of actual evapotranspiration obtained by SEB modelling (ETa eb) on Landsat-TM images. SEBAL model was integrated with the FAO 56 evaporation model, RS-retrieved vegetative biomass dynamics (by NDVI) and on-field measurements of soil moisture and potential evapotranspiration. The procedure was validated by an eddy covariance tower on a vineyard with partial soil coverage in the south of Sardinia Island, Italy. The integrated modeling approach showed a good reproduction of the time series dynamics of observed ETc act (R2 =0.71, MAE=0.54 mm d-1, RMSE=0.73 mm d-1). A daily and a cumulative monthly temporal analysis showed the importance of integrating parameters that capture changes in the soil-plant-atmosphere (SPA) continuum between Landsat acquisitions. The comparison with daily ETc act obtained by the referenced ET fraction (ETrF) method that considers only weather variability (by ETo) confirmed the lead of the proposed procedure in the spring/early summer periods when vegetation biomass changes and soil water evaporation have a significant weight in the ET process. The applied modelling approach was also robust in constructing the missing ETc act data under scenarios of limited cloud-free Landsat acquisitions. The presented integrated approach has a great potential for the near real time monitoring and scheduling of irrigation practices. Further testing of this approach with diverse dataset and the integration with the soil water modeling is to be analyzed in future work

Challenges and Knowledge Gaps with Immune Checkpoint Inhibitors Monotherapy in the Management of Patients with Non-Small-Cell Lung Cancer: a Survey of Oncologist Perceptions

Background: Immune checkpoint-inhibitors (ICIs) are changing outcomes in different cancer settings, notably for patients with non-small-cell lung cancer (NSCLC). There are, however, still important gaps of evidence for clinical practice when using these novel treatments. In this study, we assessed physicians' opinion and experience on challenges for clinical practice with ICIs monotherapy in NSCLC. Methods: A survey was conducted on experienced physicians treating patients with NSCLC with ICIs. Two rounds of pilot tests were carried out for validation among a group of experts. Topics under analysis were in relation to treatment of elderly populations, performance status, brain metastases, use of steroids or antibiotics, the effects of gut microbiome, autoimmune diseases, human immunodeficiency virus infection, solid organ transplants, use of anti-programmed cell death protein 1 versus anti-programmed death-ligand 1 drugs, atypical tumour responses, predictors of response, duration of treatment and a final open question on additional relevant challenges. Results: Two hundred and twenty-one answers were collected, including 106 (48%) valid answers from experts for final analysis (physicians who have treated at least 20 patients with NSCLC with ICIs). The vast majority agreed that the selected topics in this study are important challenges ahead and more evidence is needed. Moreover, predictors of response, treating brain metastasis, shorter duration of treatment, the effects of gut microbiome and concomitant use of steroids were voted the most important topics to be further addressed in prospective clinical research. Conclusions: This survey contributed to understanding which are the main challenges for clinical practice with ICIs monotherapy in NSCLC. It can also contribute to guide further clinical research, considering the opinions and experience of those who regularly treat NSCLC patients with ICIs.info:eu-repo/semantics/publishedVersio