Co-evolution of RDF Datasets

Linking Data initiatives have fostered the publication of large number of RDF datasets in the Linked Open Data (LOD) cloud, as well as the development of query processing infrastructures to access these data in a federated fashion. However, different experimental studies have shown that availability of LOD datasets cannot be always ensured, being RDF data replication required for envisioning reliable federated query frameworks. Albeit enhancing data availability, RDF data replication requires synchronization and conflict resolution when replicas and source datasets are allowed to change data over time, i.e., co-evolution management needs to be provided to ensure consistency. In this paper, we tackle the problem of RDF data co-evolution and devise an approach for conflict resolution during co-evolution of RDF datasets. Our proposed approach is property-oriented and allows for exploiting semantics about RDF properties during co-evolution management. The quality of our approach is empirically evaluated in different scenarios on the DBpedia-live dataset. Experimental results suggest that proposed proposed techniques have a positive impact on the quality of data in source datasets and replicas.Comment: 18 pages, 4 figures, Accepted in ICWE, 201

Thermal emission from low-field neutron stars

We present a new grid of LTE model atmospheres for weakly magnetic (B<=10e10G) neutron stars, using opacity and equation of state data from the OPAL project and employing a fully frequency- and angle-dependent radiation transfer. We discuss the differences from earlier models, including a comparison with a detailed NLTE calculation. We suggest heating of the outer layers of the neutron star atmosphere as an explanation for the featureless X-ray spectra of RX J1856.5-3754 and RX J0720.4-3125 recently observed with Chandra and XMM.Comment: 8 pages A&A(5)-Latex, 6 Figures, A&A in press. The model spectra presented here are available as XSPEC tables at http://www.astro.soton.ac.uk/~btg/outgoing/nsspec

Direct Visualization of Single Nuclear Pore Complex Proteins Using Genetically-Encoded Probes for DNA-PAINT

The nuclear pore complex (NPC) is one of the largest and most complex protein assemblies in the cell and, among other functions, serves as the gatekeeper of nucleocytoplasmic transport. Unraveling its molecular architecture and functioning has been an active research topic for decades with recent cryogenic electron microscopy and super-resolution studies advancing our understanding of the architecture of the NPC complex. However, the specific and direct visualization of single copies of NPC proteins is thus far elusive. Herein, we combine genetically-encoded self-labeling enzymes such as SNAP-tag and HaloTag with DNA-PAINT microscopy. We resolve single copies of nucleoporins in the human Y-complex in three dimensions with a precision of circa 3 nm, enabling studies of multicomponent complexes on the level of single proteins in cells using optical fluorescence microscopy

A Theoretical Analysis of Two-Stage Recommendation for Cold-Start Collaborative Filtering

In this paper, we present a theoretical framework for tackling the cold-start collaborative filtering problem, where unknown targets (items or users) keep coming to the system, and there is a limited number of resources (users or items) that can be allocated and related to them. The solution requires a trade-off between exploitation and exploration as with the limited recommendation opportunities, we need to, on one hand, allocate the most relevant resources right away, but, on the other hand, it is also necessary to allocate resources that are useful for learning the target's properties in order to recommend more relevant ones in the future. In this paper, we study a simple two-stage recommendation combining a sequential and a batch solution together. We first model the problem with the partially observable Markov decision process (POMDP) and provide an exact solution. Then, through an in-depth analysis over the POMDP value iteration solution, we identify that an exact solution can be abstracted as selecting resources that are not only highly relevant to the target according to the initial-stage information, but also highly correlated, either positively or negatively, with other potential resources for the next stage. With this finding, we propose an approximate solution to ease the intractability of the exact solution. Our initial results on synthetic data and the Movie Lens 100K dataset confirm the performance gains of our theoretical development and analysis

Isolamento e preservação de patógenos foliares obtidos de mudas seminais de eucalipto Benthamii.

SEMIC. Resumo bilingue. FLORE04

Tailored quantum dots for entangled photon pair creation

We compare the asymmetry-induced exchange splitting delta_1 of the bright-exciton ground-state doublet in self-assembled (In,Ga)As/GaAs quantum dots, determined by Faraday rotation, with its homogeneous linewidth gamma, obtained from the radiative decay in time-resolved photoluminescence. Post-growth thermal annealing of the dot structures leads to a considerable increase of the homogeneous linewidth, while a strong reduction of the exchange splitting is simultaneously observed. The annealing can be tailored such that delta_1 and gamma become comparable, whereupon the carriers are still well confined. This opens the possibility to observe polarization entangled photon pairs through the biexciton decay cascade.Comment: 4 pages, 4 figure

Systematic study of carrier correlations in the electron-hole recombination dynamics of quantum dots

The ground state carrier dynamics in self-assembled (In,Ga)As/GaAs quantum dots has been studied using time-resolved photoluminescence and transmission. By varying the dot design with respect to confinement and doping, the dynamics is shown to follow in general a non-exponential decay. Only for specific conditions in regard to optical excitation and carrier population, for example, the decay can be well described by a mono-exponential form. For resonant excitation of the ground state transition a strong shortening of the luminescence decay time is observed as compared to the non-resonant case. The results are consistent with a microscopic theory that accounts for deviations from a simple two-level picture.Comment: 8 pages, 7 figure

Effects Of Body Position And Sex Group On Tongue Pressure Generation

Fine control of orofacial musculature is necessary to precisely accelerate and decelerate the articulators across exact distances for functional speech and coordinated swallows (Amerman & Parnell, 1990; Benjamin, 1997; Kent, Duffy, Slama, Kent, & Clift, 2001). Enhanced understanding of neural control for such movements could clarify the nature of and potential remediation for some dysarthrias and other orofacial myofunctional impairments. Numerous studies have measured orolingual force and accuracy during speech and nonspeech tasks, but have focused on young adults, maximum linguapalatal pressures, and upright positioning (O’Day, Frank, Montgomery, Nichols, & McDade, 2005; Solomon & Munson, 2004; Somodi, Robin, & Luschei, 1995; Youmans, Youmans, & Stierwalt, 2009). Patients’ medical conditions or testing procedures such as concurrent neuroimaging may preclude fully upright positioning during oral motor assessments in some cases. Since judgments about lingual strength and coordination can influence clinical decisions regarding the functionality of swallowing and speech, it is imperative to understand any effects of body positioning differences. In addition, sex differences in the control of such tasks are not well defined. Therefore, this study evaluated whether pressures exerted during tongue movements differ in upright vs. supine body position in healthy middle-aged men and women. Twenty healthy middle-aged adults compressed small air-filled plastic bulbs in the oral cavity at predetermined fractions of task-specific peak pressure in a randomized block design. Tasks including phoneme repetitions and nonspeech isometric contractions were executed in upright and supine positions. Participants received continuous visual feedback regarding targets and actual exerted pressures. Analyses compared average pressure values for each subject, task, position, and effort level. Speech-like and nonspeech tongue pressures did not differ significantly across body position or sex groups. Pressure matching was significantly less accurate at higher percentages of maximum pressure for both tasks. These results provide preliminary comparative data for the clinical assessment of individuals with orofacial myofunctional and neurological disorders

Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric aggregates

The presence of oligomeric aggregates, which is often observed during the process of amyloid formation, has recently attracted much attention since it has been associated with neurodegenerative conditions such as Alzheimer's and Parkinson's diseases. We provide a description of a sequence-indepedent mechanism by which polypeptide chains aggregate by forming metastable oligomeric intermediate states prior to converting into fibrillar structures. Our results illustrate how the formation of ordered arrays of hydrogen bonds drives the formation of beta-sheets within the disordered oligomeric aggregates that form early under the effect of hydrophobic forces. Initially individual beta-sheets form with random orientations, which subsequently tend to align into protofilaments as their lengths increases. Our results suggest that amyloid aggregation represents an example of the Ostwald step rule of first order phase transitions by showing that ordered cross-beta structures emerge preferentially from disordered compact dynamical intermediate assemblies.Comment: 14 pages, 4 figure