2,324 research outputs found

    Automated acoustic intensity measurements and the effect of gear tooth profile on noise

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    Acoustic intensity measurements were made at NASA Lewis Research Center on a spur gear test apparatus. The measurements were obtained with the Robotic Acoustic Intensity Measurement System developed by Cleveland State University. This system provided dense spatial positioning, and was calibrated against a high quality acoustic intensity system. The measured gear noise compared gearsets having two different tooth profiles. The tests evaluated the sound field of the different gears for two speeds and three loads. The experimental results showed that gear tooth profile had a major effect on measured noise. Load and speed were found to have an effect on noise also

    Beyond the virtual intracranial stenting challenge 2007: non-Newtonian and flow pulsatility effects

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    The attached article is a post print version of the final published version which may be accessed at the link below. Crown Copyright (c) 2010 Published by Elsevier Ltd. All rights reserved.The Virtual Intracranial Stenting Challenge 2007 (VISC’07) is becoming a standard test case in computational minimally invasive cerebrovascular intervention. Following views expressed in the literature and consistent with the recommendations of a report, the effects of non-Newtonian viscosity and pulsatile flow are reported. Three models of stented cerebral aneurysms, originating from VISC’07 are meshed and the flow characteristics simulated using commercial computational fluid dynamics (CFD) software. We conclude that non-Newtonian and pulsatile effects are important to include in order to discriminate more effectively between stent designs

    Vascular device interaction with the endothelium

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    Copyright @ 2008 Elsevier. This is the post-print version of the article.Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and the IABP ‘correct’ the arterial flow by static dilation and by cyclical occlusion respectively. As this presentation shows, these functions are effectively modelled by current engineering practice. As interventions however, by their very nature they involve physical contact between a non-biological structure and the sensitive endothelial surface. The possible damage to the endothelium is not currently well addressed and we also consider this issue. Cerebral stents generally have two primary clinical objectives: to mechanically dilate a stenosed artery and to have minimal detrimental impact upon local blood flow characteristics. These objectives are well served at the arterial scale as these devices are evidently effective in opening up diseased arteries and restoring vital flows. However, at the near-wall micro-scale the picture is less satisfactory, as thin stent wires apply stresses to the endothelium and glycocalyx and the local flow is disturbed rather than being ideally streamlined. This causes further interaction with this endothelium topography. Wall Shear Stress (WSS) is the measure commonly used to indicate the interaction between fluid and wall but it is a broad brush approach that loses fidelity close to the wall. We will present simulation results of blood flow through a stented cerebral saccular aneurysm under these limitations of WSS. The Intra Aortic Balloon Pump (IABP) is a widely used temporary cardiac assist device. The balloon is usually inserted from the iliac artery, advanced in the aorta until it reaches the desired position; with its base just above the renal bifurcation and the tip approximately 10cm away from the aortic valve. The balloon is inflated and deflated every- (1:1), every other- (1:2) or every second (1:3) cardiac cycle. Balloon inflation, which takes place during early diastole, causes an increase in the pressure of the aortic root which leads to an increase in coronary flow. Balloon deflation which takes place during late diastole achieves one of the main IABP therapeutic effects by reducing left ventricular afterload. Unavoidably, the balloon contacts the inner wall of the aorta with every inflation/deflation cycle. This repeated event and possible contact with atherosclerotic plaque have been reported to be responsible for balloon rupture. However, there has not been a methodical study to investigate the mechanical effects of balloon-wall interaction. For example, during inflation the balloon approaches the endothelium as it displaces a volume of blood proximally and distally. This squeezing process generates shear stresses, which hasn't yet been quantified. Similarly, when the balloon moves away from the endothelium during deflation, it generates micro pressure differences that may impose stretching (pulling) stresses on the endothelium cells. Both of the above cases indicate that a very high spatial resolution is required in order to fully understand the process of interaction between device and endothelium, and to interpret the effects at the cellular level

    Charting equity in higher education: drawing the global access map

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    We know the economic benefit to individuals and to communities of increased levels of Higher Education (HE) participation. We also know that participation in HE has been expanding steadily; we anticipate there will be half a billion students participating in postsecondary education by 2030. But what do existing data tell us about who is accessing HE, and who is currently missing out? Specifically, what do we know about equity in access to high quality HE? Knowing that we are best able to manage what we measure, are institutions, nations, and international organisations capturing HE access data by critical social indicators (such as SES, gender, disability, or geographic remoteness to name but a few)
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