Socio-ecological gap analysis to forecast species range contractions for conservation

Unidad de excelencia María de Maeztu CEX2019-000940-MGeospatial approaches are increasingly vital for conservation with applications of gap analysis informing decision-making and resource allocation. We extend traditional assessments by incorporating both the spatial distribution of threats and resources to build an index of available conservation capacity across a species' range. Using 91 African carnivores, we identified locations within each species' range at risk of contraction due to a deficit of resources available to potentially thwart present threats. Our results raise new concerns for African carnivores, particularly small-bodied species, contrary to current perceptions of their extinction risks. Conservation requires both a needs assessment and prioritization scheme for planning and implementation. Range maps are critical for understanding and conserving biodiversity, but current range maps often omit content, negating important metrics of variation in populations and places. Here, we integrate a myriad of conditions that are spatially explicit across distributions of carnivores to identify gaps in capacity necessary for their conservation. Expanding on traditional gap analyses that focus almost exclusively on quantifying discordance in protected area coverage across a species' range, our work aggregates threat layers (e.g., drought, human pressures) with resources layers (e.g., protected areas, cultural diversity) to identify gaps in available conservation capacity (ACC) across ranges for 91 African carnivores. Our model indicated that all species have some portion of their range at risk of contraction, with an average of 15 percentage range loss. We found that the ACC differed based on body size and taxonomy. Results deviated from current perceptions of extinction risks for species with an International Union for Conservation of Nature (IUCN) threat status of Least Concern and yielded insights for species categorized as Data Deficient. Our socio-ecological gap analysis presents a geospatial approach to inform decision-making and resource allocation in conservation. Ultimately, our work advances forecasting dynamics of species' ranges that are increasingly vital in an era of great socio-ecological change to mitigate human-wildlife conflict and promote inclusive carnivore conservation across geographies

Comparative study to evaluate the effect of colloid coloading versus crystalloid coloading for prevention of spinal anaesthesia induced hypotension and effect on fetal Apgar score in patients undergoing elective lower segment caesarean section: a prospective observational study

Background: Spinal anesthesia for LSCS has a high incidence of maternal hypotension which can be severe and disastrous for the fetus and the mother. Coloading in these patients is a physiologically more appropriate method for preventing spinal anesthesia induced hypotension.Methods: 100 ASA I patients for elective LSCS were randomly divided into two equal groups to either receive 1000ml colloid (6% Hetastarch) or 1000ml crystalloids (Ringer lactate) as coload. NIBP, heart rate SPO2 and incidence of nausea and vomiting and use of ephedrine to treat any hypotension was recorded. Fetal outcome was measured using APGAR score at 0, 1 and 5 minutes.Results: The incidence of hypotension was lesser with colloid coload group (41.7%) as compared to the crystalloid coload group (58.3%) but the difference between the two groups was statistically insignificant. Similarly, no statistically significant difference was noted in the incidence of nausea and vomiting and Fetal APGAR score between the two groups.Conclusions: Both Colloid and Crystalloid coloading is effective in decreasing the incidence of spinal anesthesia induced hypotension during LSCS with lesser incidence of hypotension and nausea vomiting with colloid coloading

مارکس کی معاشرتی اور معاشی جدلیات اور اقبال

Since the majority of philosophers base their theories on the idea of human well-being, human sciences did not envision an ideal state but rather a setting where concrete and useful services to human well-being were provided. Your fate is determined by God, but statistics and formulas in human scientific, social, and particularly economic fields have demonstrated how the early members of humankind appropriated human resources and exploited people like commodities. This system has continually been created in this alluring manner of government. Mother's data shows that the current economic system will inevitably fail. It doesn't matter why this system failed if it was so instinctive. Iqbal's view in this regard holds that military prowess and ultimately suffers from here. We cannot dispute its scientific supremacy notwithstanding this shortcoming

’’سدھارتھ‘‘ اور ’’آگ کا دریا‘‘ کا فنی و فکری تقابلی جائزہ

The articulation of commonality and differences between two different novels on a subject of Easter Civilization and Saintism is the focal point of this research article. Hermann Hesse’s novel Siddharatha is based on the philosophy of spiritual and enlightenment and self-discovery. The novel revolves around the eastern mysticism, which progresses through the central character of the novel Siddhartha. While Aag ka Darya is an Urdu novel written by Qurrat-ul-Ain Haider, who story begins twelve thousand years ago and continues until the twenty century. In comparison to Siddhartha, this novel is longer and more detailed, featuring multiple narratives running concurrently, despite differences in language, culture, environment and region both novels blend elements of eastern culture in their presentation. The thematic similarity in both novels written by authors with different connection to different cultures, presents a unique aspect for comparative analysis

Comparative study to evaluate the effect of colloid coloading versus crystalloid coloading for prevention of spinal anaesthesia induced hypotension and effect on fetal Apgar score in patients undergoing elective lower segment caesarean section: a prospective observational study

Background: Spinal anesthesia for LSCS has a high incidence of maternal hypotension which can be severe and disastrous for the fetus and the mother. Coloading in these patients is a physiologically more appropriate method for preventing spinal anesthesia induced hypotension.Methods: 100 ASA I patients for elective LSCS were randomly divided into two equal groups to either receive 1000ml colloid (6% Hetastarch) or 1000ml crystalloids (Ringer lactate) as coload. NIBP, heart rate SPO2 and incidence of nausea and vomiting and use of ephedrine to treat any hypotension was recorded. Fetal outcome was measured using APGAR score at 0, 1 and 5 minutes.Results: The incidence of hypotension was lesser with colloid coload group (41.7%) as compared to the crystalloid coload group (58.3%) but the difference between the two groups was statistically insignificant. Similarly, no statistically significant difference was noted in the incidence of nausea and vomiting and Fetal APGAR score between the two groups.Conclusions: Both Colloid and Crystalloid coloading is effective in decreasing the incidence of spinal anesthesia induced hypotension during LSCS with lesser incidence of hypotension and nausea vomiting with colloid coloading

Frontlines and interstices in the global war on terror

In the context of the 'global war on terror' and related debates about development and the new imperialism, this essay looks at the involvement of religious absolutist militias in humanitarian aid following the Kashmir earthquake in 2005. By analysing how organizations which are considered 'terrorist' are simultaneously working with and fighting against US 'Empire', the essay considers the form of the Pakistani 'development' state, its geostrategic importance and how this relates to a religious absolutist militia infrastructure. The transformation of (often violent) religious right groups since the 1990s into development and welfare agencies is considered within the broader context of new 'hypergovernance' processes unleashed within 'Empire'. Some general comparisons are also made between the processes of juridical hypergovernance that international humanitarian and human rights NGOs initiate in the 'South', and those created by violent groups of the religious right. Both reflect contending strategies for the management of populations by bodies having ambitions on a planetary scale

Monovalent type-1 oral poliovirus vaccine given at short intervals in Pakistan: a randomised controlled, four-arm, open-label, non-inferiority trial

Background: Supplementary immunisation activities with oral poliovirus vaccines (OPVs) are usually separated by 4 week intervals; however, shorter intervals have been used in security-compromised areas and for rapid outbreak responses. We assessed the immunogenicity of monovalent type-1 oral poliovirus vaccine (mOPV1) given at shorter than usual intervals in Karachi, Pakistan.Methods: This was a multicentre, randomised, controlled, four-arm, open-label, non-inferiority trial done at five primary health-care centres in low-income communities in and around Karachi, Pakistan. Eligible participants were healthy newborn babies with a birthweight of at least 2·5 kg, for whom informed consent was provided by their parent or guardian, and lived less than 30 km from the study clinic. After receiving a birth dose of trivalent OPV, we enrolled and randomly assigned newborn babies (1:1:1:1) to receive two doses of mOPV1 with an interval of 1 week (mOPV1-1 week), 2 weeks (mOPV1-2 weeks), or 4 weeks (mOPV1-4 weeks) between doses, or two doses of bivalent OPV (bOPV) with an interval of 4 weeks between doses (bOPV-4 weeks). We gave the first study dose of OPV at age 6 weeks. We did the randomisation with a centrally generated, computerised allocation sequence with blocks of 16; participants\u27 families and study physicians could not feasibly be masked to the allocations. Trial participants were excluded from local supplementary immunisation activities during the study period. The primary outcome was non-inferiority (within a 20% margin) between groups in seroconversion to type-1 poliovirus. The primary and safety analyses were done in the per-protocol population of infants who received all three doses of vaccine. This trial is registered with ClinicalTrials.gov, number NCT01586572, and is closed to new participants.FINDINGS: Between March 1, 2012, and May 31, 2013, we enrolled 1009 newborn babies, and randomly assigned 829 (82%) to treatment. 554 (67%) of the 829 babies were included in the per-protocol analysis. Proportions of seroconversion to type-1 poliovirus were 107/135 (79%, 95% CI 72·4-86·1) with mOPV1-1 week, 108/135 (80%, 73·2-86·8) with mOPV1-2 weeks, 129/148 (87%, 80·9-92·0) with mOPV1-4 weeks, and 107/136 (79%, 71·8-85·6) with bOPV-4 weeks. Non-inferiority was shown between groups and no significant differences were noted. Ten participants died during the trial. Seven of these deaths occurred during the lead-in period before randomisation (two from diarrhoea, five from unknown causes). Three infants died from sepsis after random assignment. No deaths were attributed to the procedures or vaccines. Additionally, we noted no events of vaccine-associated paralysis.INTERPRETATION: We identified no significant differences in responses to mOPV1 given with shorter intervals between doses than with the standard 4 week intervals. The short-interval strategy could be particularly beneficial when temporary windows of opportunity for safe access can be granted in areas of conflict--eg, during cease-fire periods. In such situations, we recommend shortening the interval between OPV doses to 7 days.FUNDING: World Health Organization