An Opportunistic Approach to Adding Value to a Photograph Collection

The Semantic Web can, among other things, be used for photograph annotation. Many implementations of this idea exist, but all are limited by the fact that a human must manually create the annotations for the photographs, often using a program with which he or she is not familiar. This poster discusses an opportunistic method of photograph annotation that uses logical inference in conjunction with existing data from various sources in order to obtain information about the images being annotated

A shared journey: insights from the Banksia Younger Onset Dementia Support Group

The study of a pilot program to support people with younger onset dementia in the Frankston area of outer Melbourne has found that the participants valued being involved in initiating and organising activities that they find meaningful and enjoyable, and having the chance to share their experience with others. The report poses some questions for the further development of services

Les camps éducatifs, un voyage favorisant les compétences sociales ?: entre affirmation et interrogation

Actuellement, les camps éducatifs ou les séjours de rupture font partie d'une prise en charge, originale et dynamique, mais souvent controversée, proposée régulièrement par différentes institutions, associations ou éducateurs mobiles à de nombreux adolescents ou jeunes adultes en difficultés. La Fontanelle, les Rives du Rhône, la Brigantine, Pacifique, En Passant par la montagne, proposent des expéditions, à cours ou à long terme, à la voile, à vélo et à pied, dans le désert, en forêt ou en montagne. Notre terrain de travail va s’intéresser autant à l’aspect organisationnel et pratique de cet outil d’accompagnement qu’au vécu de cette population, engagée dans ces séjours, en manque de repères identitaires et sociaux. Nous sommes partis à la recherche de réponses en essayant de comprendre le travail éducatif proposé et d’analyser cet outil dont le rendement qualitatif est difficilement justifiable. Séjour de vacances onéreux proposé à ces jeunes ou aventure hors du commun à la base de nombreux d’apprentissages ? Les résultats ont permis de mettre en lumière la perception de l’échantillon face à cette méthode éducative. Il ressort que les usagers encore inscrits dans le processus perçoivent les camps éducatifs comme favorisant le besoin de confiance, de responsabilité et de dialogue. Les ex-­prestataires interrogés, quant à eux, partagent une partie de cet avis seulement, notamment pour le besoin de dialogue. En revanche, ils ont une vision plus transversale pour le besoin de responsabilité et de confiance. Ces derniers sont, pour eux, favorisés durant l’intégralité du processus éducatif institutionnel

UML Activity Diagram Semantics and Automated GUI Prototyping

Extended Activity Semantics (XAS) is a notation which can be used with Unified Modeling Language (UML) activity diagrams to specify user interactions with a system and to automatically generate a prototype of the graphical user interface (GUI) that would be used in these interactions. XAS has been incorporated in a CASE tool, Guibot, which has been developed as a plug-in for Rational Rose, a leading UML tool. The notation and tool address a specific gap in UML – the inability to model user interaction

Establishment and characterization of an iPSC line (UCLi023-A) derived from a Late-Onset Retinal Degeneration patient carrying a founder mutation in C1QTNF5

Late-Onset Retinal Degeneration (L-ORD) is a rare autosomal dominant macular disease, with most cases being caused by a founder mutation in C1QTNF5. Initial symptoms, which generally occur during or after the sixth decade, include abnormal dark adaptation and changes in peripheral vision. Over time, the build-up of sub-retinal pigment epithelium (RPE) deposits leads to macular atrophy and bilateral central vision loss1. Here, we describe the generation of a human induced pluripotent stem cell (iPSC) line from dermal fibroblasts of a 61-year-old L-ORD Caucasian male patient carrying the founder mutation (c.489C>G, p.Ser163Arg), using episomal reprogramming

Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats

Transcriptional profiling of specific regions of inbred rat brains reveals genes associated with alcohol preference in a known QTL locus on chromosome

Cost variability of suggested generic treatment alternatives under the Medicare Part D benefit

BACKGROUND: The substitution of generic treatment alternatives for brand-name drugs is a strategy that can help lower Medicare beneficiary out-of-pocket costs. Beginning in 2011, Medicare beneficiaries reaching the coverage gap received a 50% discount on the full drug cost of brand-name medications and a 7% discount on generic medications filled during the gap. This discount will increase until 2020, when beneficiaries will be responsible for 25% of total drug costs during the coverage gap. OBJECTIVE: To examine the cost variability of brand and generic drugs within 4 therapeutic classes before and during the coverage gap for each 2011 California stand-alone prescription drug plan (PDP) and prospective coverage gap costs in 2020 to determine the effects on beneficiary out-of-pocket drug costs. METHODS: Equivalent doses of brand and generic drugs in the following 4 pharmacological classes were examined: angiotensin II receptor blockers (ARBs), bisphosphonates, HMG-CoA reductase inhibitors (statins), and proton pump inhibitors (PPIs). The full drug cost and patient copay/coinsurance amounts during initial coverage and the coverage gap of each drug was recorded based on information retrieved from the Medicare website. These drug cost data were recorded for 28 California PDPs. RESULTS: The highest cost difference between a brand medication and a Centers for Medicare Medicaid Services (CMS)-suggested generic treatment alternative varied between $110.53 and$195.49 at full cost and between $51.37 and$82.35 in the coverage gap. The lowest cost difference varied between $38.45 and$76.93 at full cost and between -$4.11 and$18.52 during the gap. CONCLUSION: Medicare beneficiaries can realize significant out-of-pocket cost savings for their drugs by taking CMS-suggested generic treatment alternatives. However, due to larger discounts on brand medications made available through recent changes reducing the coverage gap, the potential dollar savings by taking suggested generic treatment alternatives during the gap is less compelling and will decrease as subsidies increase

Evidence for mechanical and chemical alteration of iron‐nickel meteorites on Mars: Process insights for Meridiani Planum

The weathering of meteorites found on Mars involves chemical and physical processes that can provide clues to climate conditions at the location of their discovery. Beginning on sol 1961, the Opportunity rover encountered three large iron meteorites within a few hundred meters of each other. In order of discovery, these rocks have been assigned the unofficial names Block Island, Shelter Island, and Mackinac Island. Each rock presents a unique but complimentary set of features that increase our understanding of weathering processes at Meridiani Planum. Significant morphologic characteristics interpretable as weathering features include (1) a large pit in Block Island, lined with delicate iron protrusions suggestive of inclusion removal by corrosive interaction; (2) differentially eroded kamacite and taenite lamellae in Block Island and Shelter Island, providing relative timing through crosscutting relationships with deposition of (3) an iron oxide–rich dark coating; (4) regmaglypted surfaces testifying to regions of minimal surface modification, with other regions in the same meteorites exhibiting (5) large‐scale, cavernous weathering (in Shelter Island and Mackinac Island). We conclude that the current size of the rocks is approximate to their original postfall contours. Their morphology thus likely results from a combination of atmospheric interaction and postfall weathering effects. Among our specific findings is evidence supporting (1) at least one possible episode of aqueous acidic exposure for Block Island; (2) ripple migration over portions of the meteorites; (3) a minimum of two separate episodes of wind abrasion; alternating with (4) at least one episode of coating‐forming chemical alteration, most likely at subzero temperatures