Evaluation of susceptibility of some elite cowpea cultivars to attack by Callosobruchus maculatus (F.) (Coleoptera: Bruchidae)

Fifteen elite cowpea cultivars were evaluated for their susceptibility to attack and damage by the most destructive storage pest, Callosobruchus maculatus (F.), based on the number of eggs laid, total developmental time, percentage adult emergence, seed weight loss, and growth index. Significantly, more eggs were laid on the seeds of Bengpla, California and Clemson genotypes than on those of the other cultivars. The mean developmental time (days) of C. maculatus ranged from 21.4 days on California 20 to 25.7 days on Sul 518-2 (Marfo tuya), and was significantly different between the cowpea cultivars. Adult emergence was considerably high on Bengpla, California and Clemson genotypes, but low on IT94K-445-2, Melack, and Sul 518-2. Weight loss ranged from 7 to 35.6 per cent and was significantly different between cultivars. The IT94K-445-2, IT98K-279-3 and Valenga cultivars had the least damage whilst California 11, IT87KD-1951 and Bengpla had the highest loss in seed weight. Overall, the susceptibility indices which ranged from 4.8 to 9.4 indicated that IT94K-445-2, Melack, Sul 518-2 and IT98K-279-3 were the least susceptible, whereas Bengpla, California and Clemson were the most susceptible cultivars. Therefore, it is recommended that IT94K-445-2, Sul 518-2, Melack, and IT98K-279-3 that have some degree of resistance to C. maculatus in this study should either be promoted or incorporated into breeding programmes because this will help to considerably reduce storage losses that farmers incur. Quinze variétés de dolique élite étaient évaluées pour leurs prédispositions à l'attaque et au ravage par le ravageur de stockage le plus destructeur, Callosobruchus maculatus (F.) fondées sur les variables suivantes; la quantité d'oeufs pondus, la totalité de temps de croissance, le pourcentage d'émergence en adultes, la perte de poids de graine et l'indice de croissance. Considérablement, plus des oeufs étaient pondus sur les graines de génotypes de Bengpla, de Californie et de Clemson que sur les autres variétés. Le temps (jours) moyen de croissance de C. maculatus variait de 21.4 jours sur Californie 20 à 25.7 jours sur Sul 518-2 (Marfo tuya) et était considérablement différent entre les variétés de dolique. Emergence en adultes était considérablement élevée sur les génotypes de Bengpla, de Californie et de Clemson et faible sur 1T94K-445-2, Melack et Sul 518- 2. La perte de poids variait entre 7% et 35.6% et était considérablement différente entre les variétés. 1T94K- 445-2, IT98K-279-3 et Valenga ont subi le moindre ravage alors que Californie 11, IT87KD-1951 et Bengpla avaient les pertes de poids de graine les plus élevées. D'ensemble, les indices de prédisposition qui variaient de 4.8 à 9.4 indiquent que 1T94K-445-2, Melack, Sul 518, 1T98K- 279-3 étaient les moindres prédisposées alors que Bengpla, Californie et Clemson étaient les variétés les plus prédisposées. Il est donc recommandé que 1T94K-445- 2, Sul 518-2, Melack et 1T98K-279-3 qui avaient une certaine mesure de résistance à C. maculatus dans l'étude actuelle, devraient être soit encouragés soit incorporés dans les programmes de reproduction puisque cela va aider à réduire considérablement les pertes de stockage que les agriculteurs subissent. Ghana Journal of Agricultural Science Vol. 40 (1) 2007: pp. 73-8

Dynamic Models in Atmospheric Monitoring Signal Evaluation for Safety, Health and Cost Benefits

It is prudent to interpret atmospheric monitoring signals in real time for checking the safe limits of the air conditions in underground mines. In gassy mines, real-time evaluation increases the safety of operations. In all mines, continuous monitoring and evaluation contributes to maintaining air conditions within healthy and safe limits. Signal interpretation for safety conditions in mines is difficult for many reasons. An increase in hazardous contaminant concentrations can be predicted by signal pattern recognition, root cause analysis of rapid changes toward deterioration, and forward prediction in time using algorithms and numerical models. The paper describes an early warning system for analyzing monitored signal patterns continuously in real time as well as forward predicting the various environmental and working conditions to recognize dangerous trends that may affect safety and health in underground mines. A dynamic, numerical ventilation model with heat and gas contaminant simulation components is used for the analysis of atmospheric data. Methods and test results are discussed with numerical examples for signal propagation prediction. Several mine examples are studied using controlled, synthetic data for malfunction simulations to evaluate time delays between the detection time of suspicious signal trends and the time of dangerous threshold crossing marking an accident scenario. Delay time is found in the order of 20\ua0min in the examples, signifying the useful time period for preventive intervention between EWS warning and the likely breakout of a following accident

“I am Italian in the world”: A mobile student’s story of language learning and ideological becoming

This article theorises the relationship between language and intercultural learning from a Bakhtinian dialogic perspective, based on the language learning story of Federica, a mobile student in UK higher education (HE). I first outline the context of UK HE and its internationalisation agenda, discussing how research in this field has conceptualised language, intercultural communication (IC), and international students in terms of a totalising boundary between self and other. I link this to current concerns in IC regarding the philosophical underpinnings of the field, specifically the aporia created as a result of the totalising self/other relation in prevailing IC discourse (MacDonald & O’Regan, 2013). I then present a means of addressing this aporia through a Bakhtinian theorisation of the relationship between language and intercultural learning. This theorisation offers a relational perspective on the self and the other in which intercultural learning is a process of ideological becoming (Bakhtin, 1981) with the other, enacted in, with and through language, as illustrated in Federica’s story of learning English. The article concludes with a call for language and communicative practices to be placed at the heart of HE internationalisation agendas and for HE practitioners to recognise shared responsibility for intercultural communication

Haematological and Biochemical Reference Values for Healthy Adults in the Middle Belt of Ghana

BACKGROUND: Reference values are very important in clinical management of patients, screening participants for enrollment into clinical trials and for monitoring the onset of adverse events during these trials. The aim of this was to establish gender-specific haematological and biochemical reference values for healthy adults in the central part of Ghana. METHODS: A total of 691 adults between 18 and 59 years resident in the Kintampo North Municipality and South District in the central part of Ghana were randomly selected using the Kintampo Health and Demographic Surveillance System and enrolled in this cross-sectional survey. Out of these, 625 adults made up of 316 males and 309 females were assessed by a clinician to be healthy. Median values and nonparametric 95% reference values for 16 haematology and 22 biochemistry parameters were determined for this population based on the Clinical Laboratory and Standards Institute guidelines. Values established in this study were compared with the Caucasian values being used currently by our laboratory as reference values and also with data from other African and western countries. RESULTS: REFERENCE VALUES ESTABLISHED INCLUDE: haemoglobin 113-164 g/L for males and 88-144 g/L for females; total white blood cell count 3.4-9.2 × 10(9)/L; platelet count 88-352 × 10(9)/L for males and 89-403 × 10(9)/L for females; alanine aminotransferase 8-54 U/L for males and 6-51 U/L for females; creatinine 56-119 µmol/L for males and 53-106 µmol/L for females. Using the haematological reference values based on the package inserts would have screened out up to 53% of potential trial participants and up to 25% of the population using the biochemical parameters. CONCLUSION: We have established a panel of locally relevant reference parameters for commonly used haematological and biochemical tests. This is important as it will help in the interpretation of laboratory results both for clinical management of patients and safety monitoring during a trial

Democracy, Globalization and Private Investment in Ghana

The article examines the effects of democracy and globalization on private investment in Ghana for the period 1980–2012, using the autoregressive distributed lag (ARDL) bounds test for cointegration and the error correction model (ECM). Two models are used. In Model 1, democracy is proxy by an index for institutional quality (Polity 2), while Model 2 uses an index for civil liberties as proxy for democracy. The results for Model 1 show globalization and public investment increase private investment, while exchange rate volatility and trade openness decrease private investment in both the long and short run. In addition, national income and interest rate reduce private investment in the short run. In the case of Model 2, credit to the private sector and public investment increase private investment, while exchange rate volatility and trade openness decrease private investment in both the long and short run. Finally, national income and interest rate reduce private investment in the short run. The findings and policy recommendations of the article provide vital information for policy implementation in Ghana

Updated consensus guidelines on the management of Phelan–McDermid syndrome

Phelan–McDermid syndrome (PMS) is a genetic condition caused by SHANK3 haploinsufficiency and characterized by a wide range of neurodevelopmental and systemic manifestations. The first practice parameters for assessment and monitoring in individuals with PMS were published in 2014; recently, knowledge about PMS has grown significantly based on data from longitudinal phenotyping studies and large-scale genotype–phenotype investigations. The objective of these updated clinical management guidelines was to: (1) reflect the latest in knowledge in PMS and (2) provide guidance for clinicians, researchers, and the general community. A taskforce was established with clinical experts in PMS and representatives from the parent community. Experts joined subgroups based on their areas of specialty, including genetics, neurology, neurodevelopment, gastroenterology, primary care, physiatry, nephrology, endocrinology, cardiology, gynecology, and dentistry. Taskforce members convened regularly between 2021 and 2022 and produced specialty-specific guidelines based on iterative feedback and discussion. Taskforce leaders then established consensus within their respective specialty group and harmonized the guidelines. The knowledge gained over the past decade allows for improved guidelines to assess and monitor individuals with PMS. Since there is limited evidence specific to PMS, intervention mostly follows general guidelines for treating individuals with developmental disorders. Significant evidence has been amassed to guide the management of comorbid neuropsychiatric conditions in PMS, albeit mainly from caregiver report and the experience of clinical experts. These updated consensus guidelines on the management of PMS represent an advance for the field and will improve care in the community. Several areas for future research are also highlighted and will contribute to subsequent updates with more refined and specific recommendations as new knowledge accumulates

Sero-Epidemiology as a Tool to Screen Populations for Exposure to Mycobacterium ulcerans

Sero-epidemiological analyses revealed that a higher proportion of sera from individuals living in the Buruli ulcer (BU) endemic Densu River Valley of Ghana contain Mycobacterium ulcerans 18 kDa small heat shock protein (shsp)-specific IgG than sera from inhabitants of the Volta Region, which was regarded so far as BU non-endemic. However, follow-up studies in the Volta Region showed that the individual with the highest anti-18 kDa shsp-specific serum IgG titer of all participants from the Volta Region had a BU lesion. Identification of more BU patients in the Volta Region by subsequent active case search demonstrated that sero-epidemiology can help identify low endemicity areas. Endemic and non-endemic communities along the Densu River Valley differed neither in sero-prevalence nor in positivity of environmental samples in PCR targeting M. ulcerans genomic and plasmid DNA sequences. A lower risk of developing M. ulcerans disease in the non-endemic communities may either be related to host factors or a lower virulence of local M. ulcerans strains

Examining the relationship between household air pollution and infant microbial nasal carriage in a Ghanaian cohort.

BACKGROUND: Pneumonia, a leading cause of childhood mortality, is associated with household air pollution (HAP) exposure. Mechanisms between HAP and pneumonia are poorly understood, but studies suggest that HAP may increase the likelihood of bacterial, instead of viral, pneumonia. We assessed the relationship between HAP and infant microbial nasal carriage among 260 infants participating in the Ghana Randomized Air Pollution and Health Study (GRAPHS). METHODS: Data are from GRAPHS, a cluster-randomized controlled trial of cookstove interventions (improved biomass or LPG) versus the 3-stone (baseline) cookstove. Infants were surveyed for pneumonia during the first year of life and had routine personal exposure assessments. Nasopharyngeal swabs collected from pneumonia cases (n?=?130) and healthy controls (n?=?130) were analyzed for presence of 22 common respiratory microbes by MassTag polymerase chain reaction. Data analyses included intention-to-treat (ITT) comparisons of microbial species presence by study arm, and exposure-response relationships. RESULTS: In ITT analyses, 3-stone arm participants had a higher mean number of microbial species than the LPG (LPG: 2.71, 3-stone: 3.34, p?<?0.0001, n?=?260). This difference was driven by increased bacterial (p?<?0.0001) rather than viral species presence (non-significant). Results were pronounced in pneumonia cases and attenuated in healthy controls. Higher prevalence bacterial species were Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis. Exposure-response relationships did not yield significant associations between measured CO and nasal microbial carriage. CONCLUSIONS: Our intention-to-treat findings are consistent with a link between HAP and bacterial nasal carriage. No relationships were found for viral carriage. Given the null results in exposure-response analysis, it is likely that a pollutant besides CO is driving these differences

The Critical Care Society of Southern Africa Consensus Guideline on ICU Triage and Rationing (ConICTri)

  Background. In South Africa (SA), administrators and intensive care practitioners are faced with the challenge of resource scarcity as well as an increasing demand for intensive care unit (ICU) services. ICU services are expensive, and practitioners in low- to middle-income countries experience the consequences of limited resources daily. Critically limited resources necessitate that rationing and triage (prioritisation) decisions are routinely necessary in SA, particularly in the publicly funded health sector. Purpose. The purpose of this guideline is to utilise the relevant recommendations of the associated consensus meeting document and other internationally accepted principles to develop a guideline to inform frontline triage policy and ensure the best utilisation of adult intensive care in SA, while maintaining the fair distribution of available resources. Recommendations. An overall conceptual framework for the triage process was developed. The components of the framework were developed on the basis that patients should be admitted preferentially when the likely incremental medical benefit derived from ICU admission justifies admission. An estimate of likely resource use should also form part of the triage decision, with those patients requiring relatively less resources to achieve substantial benefit receiving priority for admission. Thus, the triage system should maximise the benefits obtained from ICU resources available for the community. Where possible, practical examples of what the consensus group agreed would be considered appropriate practice under specified South African circumstances were provided, to assist clinicians with practical decision-making. It must be stressed that this guideline is not intended to be prescriptive for individual hospital or regional practice, and hospitals and regions are encouraged to develop specified local guidelines with locally relevant examples. The guideline should be reviewed and revised if appropriate within 5 years. Conclusion. In recognition of the absolute need to limit patient access to ICU because of the lack of sufficient intensive care resources in public hospitals, this guideline has been developed to guide policy-making and assist frontline triage decision-making in SA. This document is not a complete plan for quality practice, but rather a template to support frontline clinicians, guide administrators and inform the public regarding appropriate triage decision-making.

The Critical Care Society of Southern Africa Consensus Guideline on ICU triage and rationing (ConICTri)

CITATION: Joynt, G. M. et al. 2019. The Critical Care Society of Southern Africa Consensus Guideline on ICU Triage and Rationing (ConICTri). South African Medical Journal, 109(8b):630-642. doi:10.7196/SAMJ.2019.v109i8b.13The original publication is available at http://www.samj.org.za/index.php/samj/indexBackground: In South Africa (SA), administrators and intensive care practitioners are faced with the challenge of resource scarcity as well as an increasing demand for intensive care unit (ICU) services. ICU services are expensive, and practitioners in low- to middle-income countries experience the consequences of limited resources daily. Critically limited resources necessitate that rationing and triage (prioritisation) decisions are routinely necessary in SA, particularly in the publicly funded health sector. Purpose: The purpose of this guideline is to utilise the relevant recommendations of the associated consensus meeting document and other internationally accepted principles to develop a guideline to inform frontline triage policy and ensure the best utilisation of adult intensive care in SA, while maintaining the fair distribution of available resources. Recommendations: An overall conceptual framework for the triage process was developed. The components of the framework were developed on the basis that patients should be admitted preferentially when the likely incremental medical benefit derived from ICU admission justifies admission. An estimate of likely resource use should also form part of the triage decision, with those patients requiring relatively less resources to achieve substantial benefit receiving priority for admission. Thus, the triage system should maximise the benefits obtained from ICU resources available for the community. Where possible, practical examples of what the consensus group agreed would be considered appropriate practice under specified South African circumstances were provided, to assist clinicians with practical decision-making. It must be stressed that this guideline is not intended to be prescriptive for individual hospital or regional practice, and hospitals and regions are encouraged to develop specified local guidelines with locally relevant examples. The guideline should be reviewed and revised if appropriate within 5 years. Conclusion: In recognition of the absolute need to limit patient access to ICU because of the lack of sufficient intensive care resources in public hospitals, this guideline has been developed to guide policy-making and assist frontline triage decision-making in SA. This document is not a complete plan for quality practice, but rather a template to support frontline clinicians, guide administrators and inform the public regarding appropriate triage decision-making.http://www.samj.org.za/index.php/samj/article/view/12683Publisher's versio