Development of Cube Recrystallisation Texture and Microstructure of an Aluminium Alloy Suitable for Cartridge Case Manufacturing

Electron backscattered diffraction investigations on just fully recrystallised orientation image microstructures, showed that the cube-oriented grains had the largest size in all microstructures of an aluminium alloy, which have potential use in the cartridge case manufacturing for defence purpose. The simulation of cube microstructure and texture of that aluminium alloy was tried. The recrystallisation texture and microstructure simulation by the 3-D cellular automaton model with the consideration of highest mobility of 40º<111> grainboundary, predicted the volume fraction of the cube texture orientation which was validated by experiment.Defence Science Journal, 2010, 60(3), pp.330-336, DOI:http://dx.doi.org/10.14429/dsj.60.36

Synthesis, Characterization and evaluation of Anti-inflammatory and Analgesic activity of Benzothiazole derivatives

A parent benzothiazole nucleus was synthesized by para amino acetanilide, then it is subjected to treatment with various substituted aromatic aldehydes to get the corresponding Schiff’s bases followed by treatment with pthalic anhydride to form 2-(6- acetamidobenzo[d]thiazol-2-ylcarbamoyl)benzoic acid. The structures of synthesized compounds were confirmed by various spectroscopic methods such as IR, 1H NMR and mass spectroscopy. The products were evaluated for their anti-inflammatory and analgesic activities. Some of the compounds exhibited potent activities when compared with the standards

Functional Meat and Meat Products: An Overview

A food can be regarded as functional if it is satisfactorily demonstrated to beneficially affect one or more target functions in the body, beyond adequate nutritional effects, in a way that is relevant to either improved health or well-being and/or to a reduction in the risk of disease. They are very important for health and are classified on various basis such as Supplementation of functional ingredients in diets of animals which includes Conjugated linoleic acid, Vitamin E, Omega-3 (ω3) fatty acids and Selenium; enrichment of functional ingredients in meat and meat products which includes functional foods from plant sources such as Soy proteins, Wheat proteins, Fibers, Broccoli and other Cruciferous Vegetables, Citrus Fruits, Tomatoes, Flaxseed, Herbs and spices as well as functional foods from animal sources such as Fish and Dairy Products like Whey protein and Probiotics and finally production of functional components during processing which includes Curing, Fermentation, Production of antibacterial compounds like Bacteriocin and Enzyme hydrolysis of proteins. Current status of functional meat products in world and India, safety issues and future prospects has been discussed

In-vitro anti-inflammatory and antioxidant potential of Triphala guggul tablets

Current study investigated the in-vitro anti-inflammatory and antioxidant potential of successive extracts of a polyherbal formulation Lakshadi guggul tablet a combination of Indian medicinal plants viz. Commiphora mukul, Cissus quadrangularis, Laccifer lacca, Sida veronicaefolia, Terminalia arjuna and Withania somnifera. The studies were undertaken to assess the anti-inflammatory at doses levels of 200 mg and 400 mg/ml of each extract by in-vitro red blood cells membrane stabilization and antioxidant potential at doses levels of 125 μg, 250 μg and 500 μg/ml of each extract by DPPH free radical scavenging activity methods. In-vitro anti- inflammatory activity of extracts were found significant (aP<0.01, bP<0.05) red blood cells membrane stabilization effects with 66.40 % in methanol, 62.15 % in ethyl acetate, 59.39 % in chloroform extract, and 66.18% with standard drug diclofenac. Similarly, in-vitro antioxidant activity of Lakshadi guggul tablets extracts were found significant reduction in free radical scavenging activity in 49.60% in methanol, 48.10% in ethyl acetate extract and relatively similar to 52.21% of standard drugs. The results of these studies revealed that Lakshadi guggul have strong potential antioxidant and anti- inflammatory agents

Journal of Library and Information Science: A Bibliometric Study from 2013-2020

ABSTRACT PURPOSE: This study is a bibliometric analysis of the “Journal of Library and Information Science” published between 2013 to 2020. Total number of citations, year-wise distribution, authorship pattern, authors productivity, degree of collaboration of authors are examined. DESIGN/ RESEARCH METHODOLOGY/ APPROACH: The data for the period of 2013 to 2020 was collected by downloading articles from the Journal of Library and Information Science website http://jlisnet.com. References were arranged in MS Excel worksheet for the study. In this study, Subramanyam’s formula was used for measuring degree of collaboration. Further, collaboration efforts are discussed and examined. FINDINGS: 89 articles were published during the 8 years’ period and total 1865 number of citations were available in published articles. In most of the papers, joint authors contributed during the study period of this journal. RESEARCH IMPLICATIONS: In bibliometric analysis the maximum the citation frequency of an article, the highest will be the value of the journal. The bibliometric analysis also helps to trace the time gap between the publication of an article and the appearance of its citations in other journals. According to findings and analysis of the present study following suggestions are made by the authors for future research, Citation patterns of other journals and disciplines may be conducted Informatic analysis, Webometric analysis, Scientometric analysis may be conducted The Pattern of chronological authorship pattern could be explore

Impact of ICT diffusion and financial development on economic growth in developing countries

Purpose: The present study aimed to examine the relationship between information and communication technologies (ICT) diffusion, financial development and economic growth in the panel of developing countries for 2005–2019. Design/methodology/approach: The study employed the principal component analysis (PCA) to extract the index of ICT diffusion. First-generation panel unit root tests such as Levine Lin Chu (LLC), Im Pesaran Shin (IPS), Augmented Dickey-Fuller (ADF) and Phillips and Perron (PP) were employed to check the stationarity of the variables. Pedroni and Kao co-integration techniques were used to examine the existence of the long-run relationship, and co-integration coefficients were estimated using FMOLS and dynamic ordinary least squares (DOLS). The panel Granger causality approach examined the short-run and long-run causality. Findings: The results confirmed that ICT diffusion, financial development and trade openness accelerate growth, whereas inflation dampens economic growth. Further, the causality test showed bidirectional causality between ICT growth and financial development growth but a unidirectional causality from financial development to ICT diffusion in developing countries. Originality/value: The study recommends synchronizing public and private sector investment for a synergistic effect on ICT infrastructure and adequate investment in the financial sector to increase the growth rate in developing countries. Economic policies should be adopted toward incentives and subsidies to ensure affordable ICT services for disadvantaged communities. Also, training programs focussing on enhancing digital literacy to enable all segments of the population to use digital platforms for financial services are recommended.Objetivo: El presente estudio tuvo como objetivo examinar la relación entre la difusión de las tecnologías de la información y la comunicación (TIC), el desarrollo financiero y el crecimiento económico en el panel de países en desarrollo para el período 2005-2019. Diseño/metodología/enfoque: El estudio empleó el análisis de componentes principales (ACP) para extraer el índice de difusión de las TIC. Se emplearon pruebas de raíz unitaria de panel de primera generación como Levine Lin Chu (LLC), Im Pesaran Shin (IPS), Augmented Dickey-Fuller (ADF) y Phillips y Perron (PP) para verificar la estacionariedad de las variables. Se utilizaron técnicas de cointegración de Pedroni y Kao para examinar la existencia de la relación de largo plazo, y los coeficientes de cointegración se estimaron utilizando FMOLS (Mínimos cuadrados completamente modificados) y mínimos cuadrados ordinarios dinámicos (DOLS). El enfoque de causalidad del panel de Granger examinó la causalidad a corto y largo plazo. Hallazgos: Los resultados confirmaron que la difusión de las TIC, el desarrollo financiero y la apertura comercial aceleran el crecimiento, mientras que la inflación frena el crecimiento económico. Además, la prueba de causalidad mostró una causalidad bidireccional entre el crecimiento de las TIC y el crecimiento del desarrollo financiero, pero una causalidad unidireccional entre el desarrollo financiero y la difusión de las TIC en los países en desarrollo. Originalidad/valor: El estudio recomienda sincronizar la inversión de los sectores público y privado para lograr un efecto sinérgico en la infraestructura de TIC y una inversión adecuada en el sector financiero para aumentar la tasa de crecimiento en los países en desarrollo. Se deben adoptar políticas económicas orientadas a incentivos y subsidios para garantizar servicios de TIC asequibles para las comunidades desfavorecidas. Además, se recomiendan programas de capacitación centrados en mejorar la alfabetización digital para permitir que todos los segmentos de la población utilicen plataformas digitales para servicios financieros

ADVERSE DRUG REACTIONS ASSOCIATED WITH FIRST-LINE ANTI TUBERCULAR DRUGS IN A TERTIARY CARE HOSPITAL OF CENTRAL INDIA: A STUDY OF CLINICAL PRESENTATIONS, CAUSALITY, AND SEVERITY

  Objective: The objective was to study the adverse drug reactions (ADRs) associated with first-line anti-tubercular drugs for clinical presentations, causality, and severity.Methods: A retrospective study was undertaken in a 750 bedded tertiary care teaching hospital of central India for the duration of 1 year (May 2013‑May 2014). Patients diagnosed with tuberculosis and under treatment with the first-line anti-tubercular drugs were study subjects. Causality, preventability, and severity were analyzed and other parameters such as male to female ratio, most affected system, most common class of drug, and common types of ADRs, were studied.Results: Nearly 118 patients were started on anti-tubercular treatment of first-line drugs in the study duration. Out of these 45 patients suffered one or more ADRs with a total number of reported ADRs being 91. 57.77% were males. Maximum patients belonged to the age group of 31-40 years (26.66%). The most commonly involved system was hepatic and biliary system (53.33%) followed by gastrointestinal system (51.11%), the most common ADR observed was disturbed liver transaminases (33.33%) followed by nausea and vomiting (28.88%). Causality assessment by Naranjo's scale showed 58.2% ADRs scoring probable, 31.86% were of possible score, whereas 9.8% definite score category. Severity assessment shows 68.88% cases of mild grading, 31.11% of moderate and no case of severe grading was reported in the study duration.Conclusions: Vigilance regarding these ADRs occurrences can result in early diagnosis and thus, proper management can be instituted earliest. This will build confidence of patients and will decrease the dropouts which in turn can result in decrease chances of developing drug-resistant strains.Keywords: Adverse drug reactions, Multidrug resistant tuberculosis, Extensively drug-resistant tuberculosis, Causality, Naranjo's algorith

A comparative clinical evaluation of efficacy of Kati Basti with Prabhanjanam Taila and Moorchita Tila Taila in Gridhrasi w.s.r to Sciatica

Kati Basti included under various external procedures of Ayurveda, having variety of actions like the Bahya Snehana (external oleation), Swedana Chikitsa (fomentation therapy). Kati Basti is indicated in various disorders of spine and back like backache, lumbar spondylosis, sciatica, degenerative disc changes etc. Low back pain is most common complaint with a prevalence of 65 to 90%. Improper sitting postures, traveling, use of two wheeler and sports activities are few important causes of backache. Sciatica often used to describe low back pain that spreads (radiates) through the hip, to the back of the thigh, and down the inside of the leg which closely resembles with Gridhrasi. In Sharanghadhara Samhita use of Prabhanjana Taila in Ghridhrasi Vyadhi has been indicated, hence an attempt was made to compare clinically the efficacy of Kati Basti with Prabhanjanam Taila and Moorchita Tila Taila in Gridhrasi with special reference to sciatica

Type A4 truncus arteriosus: series of 3 cases focused on dual source multidetector CT angiogram findings

Truncus arteriosus (TA) is a rare congenital cardiac anomaly caused by failure of normal conotruncal septation during the fetal development. This aberration leads to a common ventricular outflow artery over the malaligned large ventricular septal defect (VSD), supplying systemic, coronary and pulmonary circulation. People with such anomalous anatomy show variable presentation from early childhood to adult life depending on the severity of defects. We here present three cases of truncus arteriosus with aortic interruption / hypoplasia-coarctation (type A4 truncus arteriosus) with focus on relevant dual source MDCTA findings

FORMULATION AND CHARACTERIZATION OF MICROBALLOONS OF NORFLOXACIN

The present study involves preparation and evaluation of floating microballoons of norfloxacin for improving the bioavailability by prolongation of gastric residence time. norfloxacin, a sparingly water soluble drug, was selected and microballoons were prepared by emulsion solvent diffusion method using Eudragit L-100 and Eudragit RS-100 in ethyl alcohol and dichloromethane organic solvent system. The formation of a sphere and hollow within the sphere was confirmed through SEM studies. The percentage of drug entrapment and recovery was found to be 75- 80%. The micromeritic properties indicated better flowability and packability of the spheres. The Buoyancy test showed good floatability of norfloxacin microballoons in the simulated gastric fluid for more than 12 h. In vitro dissolution profile showed prolonged release of drug from the formulations. Thus microballoons of norfloxacin with acrylic polymers prepared by emulsion solvent diffusion proves to be an ideal novel floating dosage form that is adaptable to any intragastric condition for controlled drug delivery and enhanced bioavailability.Keywords: norfloxacin, hollow microspheres, acrylic polymers, evaluatio