867 research outputs found
Unveiling the assessment process behind an integrated flood risk management plan
In the context of the European Floods Directive, flood risk assessment is a critical component for the definition of an integrated management plan that operates within a multidimensional landscape shaped by intricate interactions. This study explores this complex interplay using a comprehensive framework, aimed at enlightening the non-linear pathways that flood risk assessments can traverse. It adopts the Gioia Methodology within the Grounded Theory approaches, enabling a nuanced exploration of flood risk assessment dynamics. Utilizing data from an Italian case study in the Po River District, this study unveils the flood risk assessment process framework by identifying 13 first-order codes, 6 s-order themes and 3 aggregate dimensions. It introduces a qualitative self-assessment tool to facilitate integration across dimensions and enhance Directive alignment, offering valuable insights for future flood risk assessment implementations
Delegating Quantum Computation in the Quantum Random Oracle Model
A delegation scheme allows a computationally weak client to use a server's
resources to help it evaluate a complex circuit without leaking any information
about the input (other than its length) to the server. In this paper, we
consider delegation schemes for quantum circuits, where we try to minimize the
quantum operations needed by the client. We construct a new scheme for
delegating a large circuit family, which we call "C+P circuits". "C+P" circuits
are the circuits composed of Toffoli gates and diagonal gates. Our scheme is
non-interactive, requires very little quantum computation from the client
(proportional to input length but independent of the circuit size), and can be
proved secure in the quantum random oracle model, without relying on additional
assumptions, such as the existence of fully homomorphic encryption. In practice
the random oracle can be replaced by an appropriate hash function or block
cipher, for example, SHA-3, AES.
This protocol allows a client to delegate the most expensive part of some
quantum algorithms, for example, Shor's algorithm. The previous protocols that
are powerful enough to delegate Shor's algorithm require either many rounds of
interactions or the existence of FHE. The protocol requires asymptotically
fewer quantum gates on the client side compared to running Shor's algorithm
locally.
To hide the inputs, our scheme uses an encoding that maps one input qubit to
multiple qubits. We then provide a novel generalization of classical garbled
circuits ("reversible garbled circuits") to allow the computation of Toffoli
circuits on this encoding. We also give a technique that can support the
computation of phase gates on this encoding.
To prove the security of this protocol, we study key dependent message(KDM)
security in the quantum random oracle model. KDM security was not previously
studied in quantum settings.Comment: 41 pages, 1 figures. Update to be consistent with the proceeding
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The methylome of the hypothalamus of prepubertal and pubertal goats
Puberty is the fulfillment of fertility, a process involving physiological and morphological development.
It is well known that the increased hypothalamic secretion of the gonadotropin-releasing hormone
(GnRH) is essential for the activation of this process, even if the elements coordinating the timing of
puberty have not been fully identified1,2. Recent studies provide proof that there is an epigenetic
regulation of female puberty, and DNA methylation, the most studied epigenetic modification, plays a
major role in it3. We analyzed DNA methylation patterns of 5 Alpine goats at their prepubertal stage
and 5 that reached puberty in order to highlight differences in their methylome. Detection of
methylated regions across the goat genome involved a Methyl Binding Domain (MBD) enrichment
followed by deep sequencing (Hiseq2000 Illumina). The software ChIPseeqer4 permitted the
identification of peaks corresponding to hyper-methylated regions. We have observed a higher
methylation level in prepubertal goats. The distribution of the methylation peaks across the genome
and within CpG islands per chromosome per group of animals has been analyzed. Furthermore, we have
investigated differential methylation in genes associated with puberty. Specifically, Cbx7, coding for a
core component of the Polycomb group silencing complex, and GnRHR, the gene coding for GnRH
receptor, showed a higher number of peaks into two intragenic fragments within prepubertal goats.
These results, accompanied by transcriptome analysis, provide a foundation for elucidating the role of
DNA methylation in the complex mechanisms that drive puberty in goat species
A first glance on the epigenome of Capra hircus
DNA methylation and microRNAs (miRNA) are two important forms of epigenetic modifications that play an important role in gene regulation in animals. Methylation at the carbon 5 position of cytosine residues is a fundamental layer of cellular differentiation through the control of transcriptional potential. MiRNA are small noncoding RNA molecules that regulate gene expression. Complete DNA methylomes for several organisms are now available; at the present, methylome of the domestic goat is unexplored. There is also still limited knowledge about miRNAs expression profiles in small ruminant species. Therefore, to contribute information on epigenetic modification in Capra hircus, we analysed the methylome and the miRNA population of three tissues (hypothalamus, pituitary and ovary) from 3 adult Saanen goats. We used Methylated DNA binding domain sequencing with enrichment of methylated DNA fragments and next generation sequencing. We produced least 23 million reads per sample, which were aligned to the goat reference genome. Further analyses were performed to identify peaks corresponding to hyper-methylated regions. We sequenced miRNAs expressed in the three tissues with Illumina high-throughput sequencing. Reads were mapped on the Capra hircus reference genome and both known and novel miRNAs, and miRNA target sites were identified using information collected in miRBase and using specific bioinformatic tools. This study produced a comprehensive miRNA profile related to the biology of goat. Furthermore, this is the first work dealing with methylome in Capra hircus: our preliminary results could provide new information for a deeper comprehension of epigenetic mechanisms of this species
Strongly anisotropic spin relaxation in graphene/transition metal dichalcogenide heterostructures at room temperature
Graphene has emerged as the foremost material for future two-dimensional
spintronics due to its tuneable electronic properties. In graphene, spin
information can be transported over long distances and, in principle, be
manipulated by using magnetic correlations or large spin-orbit coupling (SOC)
induced by proximity effects. In particular, a dramatic SOC enhancement has
been predicted when interfacing graphene with a semiconducting transition metal
dechalcogenide, such as tungsten disulphide (WS). Signatures of such an
enhancement have recently been reported but the nature of the spin relaxation
in these systems remains unknown. Here, we unambiguously demonstrate
anisotropic spin dynamics in bilayer heterostructures comprising graphene and
WS. By using out-of-plane spin precession, we show that the spin lifetime
is largest when the spins point out of the graphene plane. Moreover, we observe
that the spin lifetime varies over one order of magnitude depending on the spin
orientation, indicating that the strong spin-valley coupling in WS is
imprinted in the bilayer and felt by the propagating spins. These findings
provide a rich platform to explore coupled spin-valley phenomena and offer
novel spin manipulation strategies based on spin relaxation anisotropy in
two-dimensional materials
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Rapid attribution of the August 2016 flood-inducing extreme precipitation in south Louisiana to climate change
A stationary low pressure system and elevated levels of precipitable water
provided a nearly continuous source of precipitation over Louisiana, United
States (US), starting around 10 August 2016. Precipitation was heaviest in
the region broadly encompassing the city of Baton Rouge, with a 3-day maximum
found at a station in Livingston, LA (east of Baton Rouge), from 12 to 14 August 2016 (648.3 mm, 25.5 inches). The intense precipitation was followed
by inland flash flooding and river flooding and in subsequent days produced
additional backwater flooding. On 16 August, Louisiana officials reported
that 30 000 people had been rescued, nearly 10 600 people had slept in
shelters on the night of 14 August and at least 60 600 homes had been
impacted to varying degrees. As of 17 August, the floods were reported to
have killed at least 13 people. As the disaster was unfolding, the Red
Cross called the flooding the worst natural disaster in the US since Super
Storm Sandy made landfall in New Jersey on 24 October 2012. Before the
floodwaters had receded, the media began questioning whether this extreme
event was caused by anthropogenic climate change. To provide the necessary
analysis to understand the potential role of anthropogenic climate change, a
rapid attribution analysis was launched in real time using the best readily
available observational data and high-resolution global climate model
simulations.
The objective of this study is to show the possibility of performing rapid
attribution studies when both observational and model data and analysis
methods are readily available upon the start. It is the authors' aspiration
that the results be used to guide further studies of the devastating
precipitation and flooding event. Here, we present a first estimate of how
anthropogenic climate change has affected the likelihood of a comparable
extreme precipitation event in the central US Gulf Coast. While the
flooding event of interest triggering this study occurred in south Louisiana,
for the purposes of our analysis, we have defined an extreme precipitation
event by taking the spatial maximum of annual 3-day inland maximum
precipitation over the region of 29–31° N, 85–95° W, which
we refer to as the central US Gulf Coast. Using observational data, we find
that the observed local return time of the 12–14 August precipitation event
in 2016 is about 550 years (95 % confidence interval (CI): 450–1450).
The probability for an event like this to happen anywhere in the region is
presently 1 in 30 years (CI 11–110). We estimate that these probabilities
and the intensity of extreme precipitation events of this return time have
increased since 1900. A central US Gulf Coast extreme precipitation event
has effectively become more likely in 2016 than it was in 1900. The global
climate models tell a similar story; in the most accurate analyses, the
regional probability of 3-day extreme precipitation increases by more than a
factor of 1.4 due to anthropogenic climate change. The magnitude of the shift in
probabilities is greater in the 25 km (higher-resolution) climate model than
in the 50 km model. The evidence for a relation to El Niño half a year
earlier is equivocal, with some analyses showing a positive connection and
others none
Greening Capitalism? A Marxist Critique of Carbon Markets
Climate change is increasingly being recognized as a serious threat to dominant modes of social organization, inspiring suggestions that capitalism itself needs to be transformed if we are to ‘decarbonize’ the global economy. Since the Kyoto Protocol in 1997, carbon markets have emerged as the main politico-economic tools in global efforts to address climate change. Newell and Paterson (2010) have recently claimed that the embrace of carbon markets by financial and political elites constitutes a possible first step towards the transformation of current modes of capitalist organization into a new form of greener, more sustainable ‘climate capitalism.’ In this paper, we argue that the institutionalization of carbon markets does not, in fact, represent a move towards the radical transformation of capitalism, but is better understood as the most recent expression of ongoing trends of ecological commodification and expropriation, driving familiar processes of uneven and crisis-prone development. In this paper, we review four critical Marxist concepts: metabolic rift (Foster, 1999), capitalism as world ecology (Moore, 2011a), uneven development and accumulation through dispossession (Harvey, 2003, 2006), and sub-imperialism (Marini, 1972, 1977), developing a framework for a Marxist analysis of carbon markets. Our analysis shows that carbon markets form part of a longer historical development of global capitalism and its relation to nature. Carbon markets, we argue, serve as creative new modes of accumulation, but are unlikely to transform capitalist dynamics in ways that might foster a more sustainable global economy. Our analysis also elucidates, in particular, the role that carbon markets play in exacerbating uneven development within the Global South, as elites in emerging economies leverage carbon market financing to pursue new strategies of sub-imperial expansion. </jats:p
Racism, crisis, Brexit
This article offers a conjunctural analysis of the financial and political crisis within which Brexit occurred with a specific attentiveness to race and racism. Brexit and its aftermath have been overdetermined by racism, including racist violence. We suggest that the Leave campaign secured its victory by bringing together two contradictory but interlocking visions. The first comprises an imperial longing to restore Britain’s place in the world as primus inter pares that occludes any coming to terms with the corrosive legacies of colonial conquest and racist subjugation. The second takes the form of an insular, Powellite narrative of island retreat from a ‘globalising’ world, one that is no longer recognisably ‘British’. Further, the article argues that an invisible driver of the Brexit vote and its racist aftermath has been a politicization of Englishness. We conclude by outlining some resources of hope that could potentially help to negotiate the current emergency
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