5,663 research outputs found

    A Variational Principle for the Asymptotic Speed of Fronts of the Density Dependent Diffusion--Reaction Equation

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    We show that the minimal speed for the existence of monotonic fronts of the equation ut=(um)xx+f(u)u_t = (u^m)_{xx} + f(u) with f(0)=f(1)=0f(0) = f(1) = 0, m>1m >1 and f>0f>0 in (0,1)(0,1) derives from a variational principle. The variational principle allows to calculate, in principle, the exact speed for arbitrary ff. The case m=1m=1 when f(0)=0f'(0)=0 is included as an extension of the results.Comment: Latex, postcript figure availabl

    Development of a theory of the spectral reflectance of minerals, part 4

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    A theory of the spectral reflectance or emittance of particulate minerals was developed. The theory is expected to prove invaluable in the interpretation of the remote infrared spectra of planetary surfaces

    Contest based on a directed polymer in a random medium

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    We introduce a simple one-parameter game derived from a model describing the properties of a directed polymer in a random medium. At his turn, each of the two players picks a move among two alternatives in order to maximize his final score, and minimize opponent's return. For a game of length nn, we find that the probability distribution of the final score SnS_n develops a traveling wave form, Prob(Sn=m)=f(mvn){\rm Prob}(S_n=m)=f(m-v n), with the wave profile f(z)f(z) unusually decaying as a double exponential for large positive and negative zz. In addition, as the only parameter in the game is varied, we find a transition where one player is able to get his maximum theoretical score. By extending this model, we suggest that the front velocity vv is selected by the nonlinear marginal stability mechanism arising in some traveling wave problems for which the profile decays exponentially, and for which standard traveling wave theory applies

    Transport properties in antiferromagnetic quantum Griffiths phases

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    We study the electrical resistivity in the quantum Griffiths phase associated with the antiferromagnetic quantum phase transition in a metal. The resistivity is calculated by means of the semi-classical Boltzmann equation. We show that the scattering of electrons by locally ordered rare regions leads to a singular temperature dependence. The rare-region contribution to the resistivity varies as TλT^\lambda with temperature T,T, where the λ\lambda is the usual Griffiths exponent which takes the value zero at the critical point and increases with distance from criticality. We find similar singular contributions to other transport properties such as thermal resistivity, thermopower and the Peltier coefficient. We also compare our results with existing experimental data and suggest new experiments.Comment: 4 pages, 1 figur

    Neural signatures of cognitive flexibility and reward sensitivity following nicotinic receptor stimulation in dependent smokers : a randomized trial

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    IMPORTANCE Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence and by pharmacotherapies such as nicotine replacement therapy and varenicline tartrate may aid cessation treatment. OBJECTIVE To independently assess the effects of nicotine dependence and stimulation of the nicotinic acetylcholine receptor on the ability to interpret valence information (reward sensitivity) and subsequently alter behavior as reward contingencies change (cognitive flexibility) in a probabilistic reversal learning task. DESIGN, SETTING, AND PARTICIPANTS Nicotine-dependent smokers and nonsmokers completed a probabilistic reversal learning task during acquisition of functional magnetic resonance imaging (fMRI) in a 2-drug, double-blind placebo-controlled crossover design conducted from January 21, 2009, to September 29, 2011. Smokers were abstinent from cigarette smoking for 12 hours for all sessions. In a fully Latin square fashion, participants in both groups underwent MRI twice while receiving varenicline and twice while receiving a placebo pill, wearing either a nicotine or a placebo patch. Imaging analysis was performed from June 15, 2015, to August 10, 2016. MAIN OUTCOME AND MEASURES A well-established computational model captured effects of smoking status and administration of nicotine and varenicline on probabilistic reversal learning choice behavior. Neural effects of smoking status, nicotine, and varenicline were tested for on MRI contrasts that captured reward sensitivity and cognitive flexibility. RESULTS The study included 24 nicotine-dependent smokers (12 women and 12 men; mean [SD] age, 35.8 [9.9] years) and 20 nonsmokers (10 women and 10 men; mean [SD] age, 30.4 [7.2] years). Computational modeling indicated that abstinent smokers were biased toward response shifting and that their decisions were less sensitive to the available evidence, suggesting increased impulsivity during withdrawal. These behavioral impairments were mitigated with nicotine and varenicline. Similarly, decreased mesocorticolimbic activity associated with cognitive flexibility in abstinent smokers was restored to the level of nonsmokers following stimulation of nicotinic acetylcholine receptors (familywise error-corrected P<.05). Conversely, neural signatures of decreased reward sensitivity in smokers (vs nonsmokers; familywise error-corrected P<.05) in the dorsal striatum and anterior cingulate cortex were not mitigated by nicotine or varenicline. CONCLUSIONS AND RELEVANCE There was a double dissociation between the effects of chronic nicotine dependence on neural representations of reward sensitivity and acute effects of stimulation of nicotinic acetylcholine receptors on behavioral and neural signatures of cognitive flexibility in smokers. These chronic and acute pharmacologic effects were observed in overlapping mesocorticolimbic regions, suggesting that available pharmacotherapies may alleviate deficits in the same circuitry for certain mental computations but not for others

    Neutron diffraction in a model itinerant metal near a quantum critical point

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    Neutron diffraction measurements on single crystals of Cr1-xVx (x=0, 0.02, 0.037) show that the ordering moment and the Neel temperature are continuously suppressed as x approaches 0.037, a proposed Quantum Critical Point (QCP). The wave vector Q of the spin density wave (SDW) becomes more incommensurate as x increases in accordance with the two band model. At xc=0.037 we have found temperature dependent, resolution limited elastic scattering at 4 incommensurate wave vectors Q=(1+/-delta_1,2, 0, 0)*2pi/a, which correspond to 2 SDWs with Neel temperatures of 19 K and 300 K. Our neutron diffraction measurements indicate that the electronic structure of Cr is robust, and that tuning Cr to its QCP results not in the suppression of antiferromagnetism, but instead enables new spin ordering due to novel nesting of the Fermi surface of Cr.Comment: Submitted as a part of proceedings of LT25 (Amsterdam 2008

    Erosion waves: transverse instabilities and fingering

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    Two laboratory scale experiments of dry and under-water avalanches of non-cohesive granular materials are investigated. We trigger solitary waves and study the conditions under which the front is transversally stable. We show the existence of a linear instability followed by a coarsening dynamics and finally the onset of a fingering pattern. Due to the different operating conditions, both experiments strongly differ by the spatial and time scales involved. Nevertheless, the quantitative agreement between the stability diagram, the wavelengths selected and the avalanche morphology reveals a common scenario for an erosion/deposition process.Comment: 4 pages, 6 figures, submitted to PR

    The Unseen World: Environmental Microbial Sequencing and Identification Methods for Ecologists

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    Microorganisms inhabit almost every environment, comprise the majority of diversity on Earth, are important in biogeochemical cycling, and may be vital to ecosystem responses to large-scale climatic change. In recent years, ecologists have begun to use rapidly advancing molecular techniques to address questions about microbial diversity, biogeography, and responses to environmental change. Studies of microbes in the environment generally focus on three broad objectives: determining which organisms are present, what their functional capabilities are, and which are active at any given time. However, comprehending the range of methodologies currently in use can be daunting. To provide an overview of environmental microbial sequence data collection and analysis approaches, we include case studies of microbiomes ranging from the human mouth to geothermal springs. We also suggest contexts in which each technique can be applied and highlight insights that result from their use
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