Finding A Place in the World: The Experience of Recovery from Severe Mental Illness

This hermeneutic phenomenological study of 45 adults with serious and persistent mental illness (SPMI) examines the experience of recovery over 3 years. After a brief review of the results from the first two phases, this article reports the findings from the third phase of the recovery process. Five essential themes are identified: (1) reintegration in the community; (2) reintegration with family and friends; (3) reintegration with the case manager; (4) reintegration with oneself; (5) barriers to social inclusion. Findings highlight the unmet needs for consumers in their relationships with case managers and barriers to inclusion at the macro level. Implications for practice include the delineation of client and case manager tasks specific to each essential theme

African Americans and Recovery from Severe Mental Illness

This mixed methods study examined the lived experience of African American persons recovering from serious and persistent mental illness (SPMI) and assessed changes in demoralization, engulfment and coping over time. Psychological measures were administered and semi-structured interviews were conducted at three time points (6, 12, and 18 months) with nine African Americans with SPMI. Qualitative analysis was done from an Afrocentric perspective. The interviews were transcribed, read and coded to cluster thematic aspects in each case and across cases. Atlas-ti was used to recode transcripts and retrieve quotes to dimensionalize each essential theme. Four themes were identified: 1) striving for normalcy, 2) striving for a positive and proactive outlook, 3) mastering the challenges posed by mental illness, and 4) leaning on the supports that watch out for and over me. Paired t-tests were performed on the dependent variables of demoralization, coping, and engulfment. There was a significant change in reduction of demoralization and increase in coping from Time 1 to Time 2. There was no significant change in engulfment. These changes are noteworthy as participants averaged 21 years of illness. The relationship between the quantitative results and qualitative findings are discussed. Results have implications for practice and improving recovery-oriented services to African Americans. For example, case managers are advised to consider mental health stigma and anti stigma interventions that are inclusive of racial discrimination and expand their cultural sensitivity to include the sense of endangerment experienced by African American clients. Four African American consultants critiqued the study anonymously

Development and Validation of Molecular Markers for \u3cem\u3ePhytophthora medicaginis\u3c/em\u3e Resistance in Lucerne

Resistance to Phytophthora medicaginis is an essential attribute to incorporate into lucerne (Medicago sativa) cultivars which are likely to be grown on heavy soils or in conditions where the soil remains excessively wet for prolonged periods. Current breeding strategies rely on recurrent phenotypic selection to maintain adequate levels of resistance in newly developed synthetic cultivars. However, little is known about the source or mechanism(s) of genetic resistance operating in the cultivar. A genetic linkage map was generated from a tetraploid M. sativa population using SSR markers anchored to existing genetic and physical maps. Large effect QTL were identified on linkage groups 2, 5, 6 and 7, each of which contributed between 11-30% of the phenotypic variation. Evaluation of the marker-trait associations in another sampling of the same population was undertaken, using a different isolate of P. medicaginis. The findings indicate that in the lucerne genotype examined in this study, a network of interactions involving at least three common loci, contribute to resistance to P. medicaginis. An alignment of the resistance loci identified in this study with those previously identified provided a framework for cataloguing the diversity of resistance loci present in lucerne, and will be used to guide future lucerne breeding efforts

Contributions of greenhouse gas forcing and the Southern Annular Mode to historical Southern Ocean surface temperature trends

We examine the 1979-2014 Southern Ocean (SO) sea surface temperature (SST) trends simulated in an ensemble of coupled general circulation models and evaluate possible causes of the models’ inability to reproduce the observed 1979-2014 SO cooling. For each model we estimate the response of SO SST to step changes in greenhouse gas (GHG) forcing and in the seasonal indices of the Southern Annular Mode (SAM). Using these step-response functions, we skillfully reconstruct the models’ 1979-2014 SO SST trends. Consistent with the seasonal signature of the Antarctic ozone hole and the seasonality of SO stratification, the summer and fall SAM exert a large impact on the simulated SO SST trends. We further identify conditions that favor multidecadal SO cooling: 1) a weak SO warming response to GHG forcing; 2) a strong multidecadal SO cooling response to a positive SAM trend; 3) a historical SAM trend as strong as in observations

Shareholder protection, income inequality and social health:a proposed research agenda

This paper develops a proposed research agenda in order to highlight how corporate governance, accounting and company law are relevant to the consideration of income inequality and wider social health. To illustrate this proposed research agenda, this paper draws on corporate governance research in the law and finance tradition, as well as macro-level studies in accounting concerned with the wider corporate governance context, in order to consider the association between shareholder protection, income inequality and child mortality. Under 5 child mortality is an objective indication of a country’s ability to nurture its children. In an influential body of work, La Porta et al. (1997a, 1997b, 1998, 2008) concluded that a common law legal system which protected the interests of shareholders gave rise to better economic and social outcomes. However, drawing on corporate governance and accounting literature we contend that such a conclusion is flawed. The findings of this paper suggest that common law countries (i.e. those with the greater legal protection for investors) have worse social outcomes in terms of under-5 child mortality.PostprintPeer reviewe

Accounting for changing temperature patterns increases historical estimates of climate sensitivity

Eight atmospheric general circulation models (AGCMs) are forced with observed historical (1871–2010) monthly sea surface temperature and sea ice variations using the Atmospheric Model Intercomparison Project II data set. The AGCMs therefore have a similar temperature pattern and trend to that of observed historical climate change. The AGCMs simulate a spread in climate feedback similar to that seen in coupled simulations of the response to CO2 quadrupling. However, the feedbacks are robustly more stabilizing and the effective climate sensitivity (EffCS) smaller. This is due to a pattern effect, whereby the pattern of observed historical sea surface temperature change gives rise to more negative cloud and longwave clear‐sky feedbacks. Assuming the patterns of long‐term temperature change simulated by models, and the radiative response to them, are credible; this implies that existing constraints on EffCS from historical energy budget variations give values that are too low and overly constrained, particularly at the upper end. For example, the pattern effect increases the long‐term Otto et al. (2013, https://doi.org/10.1038/ngeo1836) EffCS median and 5–95% confidence interval from 1.9 K (0.9–5.0 K) to 3.2 K (1.5–8.1 K

Emission-line Helium Abundances in Highly Obscured Nebulae

This paper outlines a way to determine the ICF using only infrared data. We identify four line pairs, [NeIII] 36\micron/[NeII] 12.8\micron, [NeIII]~15.6\micron /[NeII] 12.8\micron, [ArIII] 9\micron/[ArII] 6.9\micron, and [ArIII] 21\micron/[ArII] 6.9\micron, that are sensitive to the He ICF. This happens because the ions cover a wide range of ionization, the line pairs are not sensitive to electron temperature, they have similar critical densities, and are formed within the He$^+$/H$^+$ region of the nebula. We compute a very wide range of photoionization models appropriate for galactic HII regions. The models cover a wide range of densities, ionization parameters, stellar temperatures, and use continua from four very different stellar atmospheres. The results show that each line pair has a critical intensity ratio above which the He ICF is always small. Below these values the ICF depends very strongly on details of the models for three of the ratios, and so other information would be needed to determine the helium abundance. The [Ar III] 9\micron/[ArII] 6.9\micron ratio can indicate the ICF directly due to the near exact match in the critical densities of the two lines. Finally, continua predicted by the latest generation of stellar atmospheres are sufficiently hard that they routinely produce significantly negative ICFs.Comment: Accepted by PASP. Scheduled for the October 1999 issue. 11 pages, 5 figure

A 4q35.2 subtelomeric deletion identified in a screen of patients with co-morbid psychiatric illness and mental retardation

BACKGROUND: Cryptic structural abnormalities within the subtelomeric regions of chromosomes have been the focus of much recent research because of their discovery in a percentage of people with mental retardation (UK terminology: learning disability). These studies focused on subjects (largely children) with various severities of intellectual impairment with or without additional physical clinical features such as dysmorphisms. However it is well established that prevalence of schizophrenia is around three times greater in those with mild mental retardation. The rates of bipolar disorder and major depressive disorder have also been reported as increased in people with mental retardation. We describe here a screen for telomeric abnormalities in a cohort of 69 patients in which mental retardation co-exists with severe psychiatric illness. METHODS: We have applied two techniques, subtelomeric fluorescence in situ hybridisation (FISH) and multiplex amplifiable probe hybridisation (MAPH) to detect abnormalities in the patient group. RESULTS: A subtelomeric deletion was discovered involving loss of 4q in a patient with co-morbid schizoaffective disorder and mental retardation. CONCLUSION: The precise region of loss has been defined allowing us to identify genes that may contribute to the clinical phenotype through hemizygosity. Interestingly, the region of 4q loss exactly matches that linked to bipolar affective disorder in a large multiply affected Australian kindred

The end of the world, or just 'goodbye to all that'? Contextualising the red deer heap from Links of Noltland, Westray, within late 3rd-millennium cal BC Orkney

As part of a major international research project, The Times of Their Lives, a programme of radiocarbon dating and Bayesian modelling was undertaken to refine the chronology of activities in one small but important part of the extensive Late Neolithic and Bronze Age settlement on Links of Noltland on the island of Westray, Orkney. The selected area (Trench D) is well known for having produced, next to a wall, the remains of a heap of at least 15 red deer carcasses, on top of which had been placed a large cod, a gannet’s wing along with part of a greater black-backed gull, and a pair of large antlers. This remarkable deposit had been preceded by, and was followed by, periods of cultivation and the deposition of domestic refuse. Refined date estimates have been produced, based on 18 radiocarbon determinations obtained from 16 samples from Trench D (including nine newly obtained dates, three from individual deer in the heap). These clarify when, during this long sequence of activities, the deer were heaped up: probably in the 22nd century cal bc, around the same time as Beaker pottery was deposited elsewhere on the Links. This allows comparison between the dated activities in this part of the site with activity elsewhere on the Links and also with other episodes of deer deposition in 3rd-millennium cal bc Orkney. It encourages exploration of the possible reasons for what appears to be a remarkable act of structured deposition. The significance of an earlier, much larger scale deposit featuring cattle remains at Ness of Brodgar is discussed in exploring the nature of Orcadian society and practices during the second half of the 3rd millennium cal bc