106 research outputs found

    La atenuación en la traducción de textos periodísticos de publicación bilingüe

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    First approach to the identification of mitigation/intensification markers in translating journalistic articles from bilingual publication in English and its translation into Spanish. There are three articles from Newsweek Magazine, a useful tool to use with translation students. The objective is the Annotated Translation of finished articles and book chapters that, after a pre-screening analysis, foster the translation of the Spanish version from written English texts. The first journalistic article with a historical theme is: The Return of Ruthless Richard – El Regreso del despiadado Ricardo (Ricardo III), used to detect the mitigation/intensification markers in both versions. Steps: 1. Sentence by sentence analysis in English, to find mitigation characteristics. 2. Review selected sentences in English with the Spanish counterpart. 3. Comparison and contrast of both versions. 4. Discuss similarities/differences to notice if the transfer of markers signals mitigation/intensification in both versions. 5. Discuss findings and write comments of translation aspects whose changes are discussed: annotated translation. Although most mitigation studies are based on oral discourse (not excluding the written text), this research considers written texts as a means and an end, in the observation and description, since original versions are unchangeable; this opens the option to edit and modify, which is promoted, before the final version elaborated between students and researchers is reached. Some comments are included as the result of what is described above.Primer acercamiento a la identificación de marcadores de atenuación-intensificación en la traducción de artículos periodísticos de publicación bilingüe, inglés y español. Son tres artículos de la Revista Newsweek, útil herramienta para alumnos, cuya especialidad es traducción. Objetivo principal: la Traducción Comentada de artículos y capítulos de libros previamente seleccionados que fomenten la traducción al español de textos en inglés. El primer artículo periodístico con tema histórico es: The Return of Ruthless Richard – El Regreso del despiadado Ricardo (Ricardo III), para detectar marcadores de atenuación/intensificación. Pasos: 1. Análisis de oración por oración en inglés donde haya rasgos de atenuación. 2. Revisión de la traducción del inglés al español para revisar si hay marcadores de atenuación. 3. Comparación y contraste de ambas versiones 4. Discutir similitudes y diferencias para ver si el traspaso de los marcadores señala atenuación- intensificación. 5. Discusión de hallazgos y redacción de comentarios del proceso de Traducción para discutir cambios, esto es, Traducción Comentada. Aunque la mayoría de los estudios de atenuación se basan en el discurso oral (sin excluir el texto escrito), en esta investigación, lo escrito es medio y fin observable y descriptible de las versiones originales que son inamovibles; esto permite la opción de editar y modificar, lo cual se promueve antes de presentar la versión final entre alumnos e investigadores. Se incluyen comentarios, resultado de lo descrito anteriormente

    Efecto antifúngico de esporas encapsuladas de Metarhizium anisopliae sobre el desarrollo de plantas de frijol (Phaseolus vulgaris L) infectadas con Fusarium moniliforme

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    La producción anual del cultivo de frijol (Phaseolus vulgaris L.) en México se reduce principalmente por enfermedades y plagas. Una alternativa de control biológico es el empleo de esporas de Metarhizium anisopliae por su capacidad de colonizar la rizosfera, pero su efectividad disminuye por la sensibilidad a factores ambientales. Por tanto, el objetivo de este estudio fue analizar el potencial de biocontrol de una formulación de alginato con esporas de M. anisopliae en el cultivo de frijol infectado con Fusarium. Se planteó un diseño experimental completamente al azar, utilizando plantas sanas como control, también se inocularon de plantas con una suspensión de Fusarium oxysporum en el sustrato y adicionalmente a una parte de estas se les depositó en la base del tallo 1 g de cápsulas de alginato que contenían esporas de M. anisopliae por planta, se midieron los parámetros morfométricos cada 8 días durante 8 semanas, así como la aparición de síntomas de fusariosis. Tras analizar los datos obtenidos se observó que hubo diferencias significativas a los 64 días después de la inoculación (ddi) siendo mayor el peso seco foliar y de raíces, así como la longitud de raíz en las plantas donde hubo interacción de Fusarium y las esporas encapsuladas de Metarhizium, esto sugiere que la presencia de ambos microorganismos afectó de forma positiva el metabolismo de las plantas, superando los beneficios de Metarhizium como promotor de crecimiento. Además, se observó que el porcentaje de incidencia en la raíz disminuyó con el tratamiento 4 sin presentar diferencia significativa de 32 a 64 ddi con valores similares al tratamiento 3 a los 16 días. Se concluyó que la aplicación de esporas encapsuladas de M. anisopliae es una opción viable para reducir el efecto del marchitamiento por Fusarium en el cultivo de frijol

    Protoindustrialización, industrialización y desindustrialización en la historia de México

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    1 archivo PDF (292 páginas)Conjunto de trabajos que lo mismo buscan identificar embriones de industrialización que apuntar los vaivenes de este proceso a lo largo del siglo XIX como abordar las políticas de fomento a la industrialización que la impulsan a lo largo de la primera mitad del siglo XX, así como el desmantelamiento industrial que se vive con una nueva fase de desarrollo con características neoliberales en un contexto de globalización que exige recuperar la memoria en el tiempo largo para sacar de ella nuevas alternativas de desarrollo y formas de organización productiva. En esta perspectiva, da cuenta de algunas experiencias protoindustriales e industriales en sectores que, en su momento, fueron claves para la economía de la colonia y posterionnente en el México Independiente: minería, textiles, azúcar, manufacturas así como las oportunidades que abre un nuevo orden económico signado por la informática

    CAPN3, DCT, MLANA and TYRP1 are overexpressed in skin of vitiligo vulgaris Mexican patients

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    Abstract. Vitiligo is a disorder causing skin depigmentation, in which several factors have been proposed for its pathogenesis: Environmental, genetic and biological aspects of melanocytes, even those of the surrounding keratinocytes. However, the lack of understanding of the mechanisms has complicated the task of predicting the development and progression. The present study used microarray analysis to characterize the transcriptional profile of skin from Vitiligo Vulgaris (VV) patients and the identified transcripts were validated using targeted high-throughput RNA sequencing in a broader set of patients. For microarrays, mRNA was taken from 20 skin biopsies of 10 patients with VV (pigmented and depigmented skin biopsy of each), and 5 biopsies of healthy subjects matched for age and sex were used as a control. A signature was identified that contains the expression pattern of 722 genes between depigmented vitiligo skin vs. healthy control, 1,108 between the pigmented skin of vitiligo vs. healthy controls and 1,927 between pigmented skin, depigmented vitiligo and healthy controls (P<0.05; false discovery rate, <0.1). When comparing the pigmented and depigmented skin of patients with vitiligo, which reflects the real difference between both skin types, 5 differentially expressed genes were identified and further validated in 45 additional VV patients by RNA sequencing. This analysis showed significantly higher RNA levels of calpain-3, dopachrome tautomerase, melan-A and tyrosinase-related protein-1 genes. The data revealed that the pigmented skin of vitiligo is already affected at the level of gene expression and that the main differences between pigmented and non-pigmented skin are explained by the expression of genes associated with pigment metabolism

    Rationale and design of the Concordance study between FFR and iFR for the assessment of lesions in the left main coronary artery. The ILITRO-EPIC-07 Trial

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    Introduction and objectives: Patients with left main coronary artery (LMCA) stenosis have been excluded from the trials that support the non-inferiority of the instantaneous wave-free ratio (iFR) compared to the fractional flow reserve (FFR) in the decision-making process of coronary revascularization. This study proposes to prospectively assess the concordance between the two indices in LMCA lesions and to validate the iFR cut-off value of 0.89 for clinical use. Methods: National, prospective, and observational multicenter registry of 300 consecutive patients with intermediate lesions in the LMCA (angiographic stenosis, 25% to 60%. A pressure gudiewire study and determination of the RFF and the iFR will be performed: in the event of a negative concordant result (FFR > 0.80/iFR > 0.89), no treatment will be performed; in case of a positive concordant result (FFR 0.80/iFR 0.89), an intravascular echocardiography will be performed and revascularization will be delayed if the minimum lumen area is > 6 mm(2). The primary clinical endpoint will be a composite of cardiovascular death, LMCA lesion-related non-fatal infarction or need for revascularization of the LMCA lesion at 12 months. Conclusions: Confirm that an iFR-guided decision-making process in patients with intermediate LMCA stenosis is clinically safe and would have a significant clinical impact. Also, justify its systematic use when prescribing treatment in these potentially high-risk patients

    Impact of operatoŕs experience on peri-procedural outcomes with Watchman FLX: Insights from the FLX-SPA registry

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    Background: The Watchman FLX is a device upgrade of the Watchman 2.5 that incorporates several design enhancements intended to simplify left atrial appendage occlusion (LAAO) and improve procedural outcomes. This study compares peri-procedural results of LAAO with Watchman FLX (Boston Scientific, Marlborough, Massachusetts) in centers with varying degrees of experience with the Watchman 2.5 and Watchman FLX. Methods: Prospective, multicenter, 'real-world' registry including consecutive patients undergoing LAAO with the Watchman FLX at 26 Spanish sites (FLX-SPA registry). Implanting centers were classified according to the center's prior experience with the Watchman 2.5. A further division of centers according to whether or not they had performed ≤ 10 or > 10Watchman FLX implants was prespecified at the beginning of the study. Procedural outcomes of institutions stratified according to their experience with the Watchman 2.5 and FLX devices were compared. Results: 359 patients [mean age 75.5 (SD8.1), CHA2DS2-VASc 4.4 (SD1.4), HAS-BLED 3.8(SD0.9)] were included. Global success rate was 98.6%, successful LAAO with the first selected device size was achieved in 95.5% patients and the device was implanted at first attempt in 78.6% cases. There were only 9(2.5%) major peri-procedural complications. No differences in efficacy or safety results according to the centeŕs previous experience with Watchman 2.5 and procedural volume with Watchman FLX existed. Conclusions: The Watchman FLX attains high procedural success rates with complete LAA sealing in unselected, real-world patients, along with a low incidence of peri-procedural complications, regardless of operatoŕs experience with its previous device iteration or the number of Watchman FLX devices implanted

    RICORS2040 : The need for collaborative research in chronic kidney disease

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    Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true

    Resultados Semilleros de Investigación 2009-2010

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    La publicación recoge los doce informes finales de investigación presentados por los estudiantes de ocho Semilleros 1 y cuatro Semilleros 2, correspondientes a la convocatoria 2009–2010 y se constituye en el Número 25 de la Serie de Investigaciones en Construcción, si bien este es el primer Número publicado en formato digital que UNIJUS se permite poner a disposición no sólo de la comunidad universitaria, sino también de la sociedad colombiana e internacional, interesada en los temas estudiados por los jóvenes investigadores de la Facultad de Derecho, Ciencias Políticas y Sociales de la Universidad Nacional de Colombia

    Métodos y técnicas de monitoreo y predicción temprana en los escenarios de riesgos socionaturales

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    Esta obra concentra los métodos y las técnicas fundamentales para el seguimiento y monitoreo de las dinámicas de los escenarios de riesgos socionaturales (geológicos e hidrometeorológicos) y tiene como objetivo general orientar, apoyar y acompañar a los directivos y operativos de protección civil en aterrizar las acciones y políticas públicas enfocadas a la gestión del riesgo local de desastre
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