124 research outputs found

    Universe acceleration and fine structure constant variation in BSBM theory

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    In this work we investigate the utility of using SNe Ia observations in constraining the cosmological parameters in BSBM theory where a scalar field is responsible for both fine structure constant variation and late time universe acceleration. The model is discussed in the presence of an exponential self potential for the scalar field. Stability and phase space analysis of the solutions are studied. The model is tested against observational data for Hubble parameter and quasar absorption spectra. With the best fitted model parameters, the theory predicts a good match with the experimental results and exhibits fine structure constant variation. The analysis also shows that for the equation of state parameter, recent universe acceleration and possible phantom crossing in future is forecasted.Comment: 14 pages, 10 figures, final version with minor modification accepted to be published in JCA

    Epidemics on plants: Modeling long-range dispersal on spatially embedded networks

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    Here we develop an epidemic model that accounts for long-range dispersal of pathogens between plants. This model generalizes the classical compartmental models–Susceptible-Infected-Susceptible (SIS) and Susceptible-Infected-Recovered (SIR)–to take into account those factors that are key to understand epidemics in real plant populations. These ingredients are the spatial characteristics of the plots and fields in which plants are embedded and the effect of long-range dispersal of pathogens. The spatial characteristics are included through the use of random rectangular graphs which allow to consider the effects of the elongation of plots and fields, while the long-range dispersal is implemented by considering transformations, such as the Mellin and Laplace transforms, of a generalization of the adjacency matrix of the geometric graph. Our results point out that long-range dispersal favors the propagation of pathogens while the elongation of plant plots increases the epidemic threshold and decreases dramatically the number of affected plants. Interestingly, our model is able of reproducing the existence of patchy regions of infected plants and the absence of a clear propagation front centered in the initial infected plants, as it is observed in real plant epidemics

    Fotometría fotográfica con un detector reticón

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    La mayoría de los datos utilizados en la fotometría fotográfica estelar han sido medidos con fotómetros a iris (IDP). Referencias a los numerosos trabajos sobre los aspectos metodológicos pueden verse en Schaeffer (1981).Asociación Argentina de Astronomí

    Tecnología para la producción de fríjol arbustivo en las zonas de clima medio del departamento de Antioquia

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    Se indican las prácticas de manejo, del cultivo de fríjol arbustivo, para las zonas de clima medio del departamento de Antioquia. Se señalan los sistemas de siembra más adecuados para la región, las épocas de siembra y la tecnología indicada para la preparación del suelo, fertilización, control de malezas, plagas y enfermedades. Se describen los patógenos e insectos que afectan el cultivo, los métodos de cosecha y postcosecha utilizados y los sistemas de producción de semillas de fríjol en condiciones del pequeño agricultorFríjol-Phaseolus vulgari

    Influence of a Uniform Current on Collective Magnetization Dynamics in a Ferromagnetic Metal

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    We discuss the influence of a uniform current, j⃗\vec{j} , on the magnetization dynamics of a ferromagnetic metal. We find that the magnon energy ϵ(q⃗)\epsilon(\vec{q}) has a current-induced contribution proportional to q⃗⋅J⃗\vec{q}\cdot \vec{\cal J}, where J⃗\vec{\cal J} is the spin-current, and predict that collective dynamics will be more strongly damped at finite j⃗{\vec j}. We obtain similar results for models with and without local moment participation in the magnetic order. For transition metal ferromagnets, we estimate that the uniform magnetic state will be destabilized for j≳109Acm−2j \gtrsim 10^{9} {\rm A} {\rm cm}^{-2}. We discuss the relationship of this effect to the spin-torque effects that alter magnetization dynamics in inhomogeneous magnetic systems.Comment: 12 pages, 2 figure

    <sup>89</sup>Zr-Trastuzumab PET/CT Imaging of HER2-Positive Breast Cancer for Predicting Pathological Complete Response after Neoadjuvant Systemic Therapy:A Feasibility Study

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    Background: Approximately 20% of invasive ductal breast malignancies are human epidermal growth factor receptor 2 (HER2)-positive. These patients receive neoadjuvant systemic therapy (NAT) including HER2-targeting therapies. Up to 65% of patients achieve a pathological complete response (pCR). These patients might not have needed surgery. However, accurate preoperative identification of a pCR remains challenging. A radiologic complete response (rCR) on MRI corresponds to a pCR in only 73% of patients. The current feasibility study investigates if HER2-targeted PET/CT-imaging using Zirconium-89 (89Zr)-radiolabeled trastuzumab can be used for more accurate NAT response evaluation. Methods: HER2-positive breast cancer patients scheduled to undergo NAT and subsequent surgery received a 89Zr-trastuzumab PET/CT both before (PET/CT-1) and after (PET/CT-2) NAT. Qualitative and quantitative response evaluation was performed. Results: Six patients were enrolled. All primary tumors could be identified on PET/CT-1. Four patients had a pCR and two a pathological partial response (pPR) in the primary tumor. Qualitative assessment of PET/CT resulted in an accuracy of 66.7%, compared to 83.3% of the standard-of-care MRI. Quantitative assessment showed a difference between the SUVR on PET/CT-1 and PET/CT-2 (ΔSUVR) in patients with a pPR and pCR of −48% and −90% (p = 0.133), respectively. The difference in tumor-to-blood ratio on PET/CT-1 and PET/CT-2 (ΔTBR) in patients with pPR and pCR was −79% and −94% (p = 0.133), respectively. Three patients had metastatic lymph nodes at diagnosis that were all identified on PET/CT-1. All three patients achieved a nodal pCR. Qualitative assessment of the lymph nodes with PET/CT resulted in an accuracy of 66.7%, compared to 50% of the MRI. Conclusions: NAT response evaluation using 89Zr-trastuzumab PET/CT is feasible. In the current study, qualitative assessment of the PET/CT images is not superior to standard-of-care MRI. Our results suggest that quantitative assessment of 89Zr-trastuzumab PET/CT has potential for a more accurate response evaluation of the primary tumor after NAT in HER2-positive breast cancer.</p

    Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder

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    IMPORTANCE Neuroticism is a pervasive risk factor for psychiatric conditions. It genetically overlaps with major depressive disorder (MDD) and is therefore an important phenotype for psychiatric genetics. The Genetics of Personality Consortium has created a resource for genome-wide association analyses of personality traits in more than 63 000 participants (including MDD cases)
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