Superplastic deformation of directionally solidified nanofibrillar Al2O3-Y3Al5O12-ZrO2 eutectics

Nanofibrillar Al2O3–Y3Al5O12–ZrO2 eutectic rods were manufactured by directional solidification from the melt at high growth rates in an inert atmosphere using the laser-heated floating zone method. Under conditions of cooperative growth, the ternary eutectic presented a homogeneous microstructure, formed by bundles of single-crystal c-oriented Al2O3 and Y3Al5O12 (YAG) whiskers of ≈100 nm in width with smaller Y2O3-doped ZrO2 (YSZ) whiskers between them. Owing to the anisotropic fibrillar microstructure, Al2O3–YAG–YSZ ternary eutectics present high strength and toughness at ambient temperature while they exhibit superplastic behavior at 1600 K and above. Careful examination of the deformed samples by transmission electron microscopy did not show any evidence of dislocation activity and superplastic deformation was attributed to mass-transport by diffusion within the nanometric domains. This combination of high strength and toughness at ambient temperature together with the ability to support large deformations without failure above 1600 K is unique and shows a large potential to develop new structural materials for very high temperature structural applications

Catheter ablation vs. antiarrhythmic drug treatment of persistent atrial fibrillation : A multicentre, randomized, controlled trial (SARA study)

BackgroundCatheter ablation (CA) is a highly effective therapy for the treatment of paroxysmal atrial fibrillation (AF) when compared with antiarrhythmic drug therapy (ADT). No randomized studies have compared the two strategies in persistent AF. The present randomized trial aimed to compare the effectiveness of CA vs. ADT in treating persistent AF.Methods and resultsPatients with persistent AF were randomly assigned to CA or ADT (excluding patients with long-standing persistent AF). Primary endpoint at 12-month follow-up was defined as any episode of AF or atrial flutter lasting >24 h that occurred after a 3-month blanking period. Secondary endpoints were any atrial tachyarrhythmia lasting >30 s, hospitalization, and electrical cardioversion. In total, 146 patients were included (aged 55 ± 9 years, 77% male). The ADT group received class Ic (43.8%) or class III drugs (56.3%). In an intention-to-treat analysis, 69 of 98 patients (70.4%) in the CA group and 21 of 48 patients (43.7%) in the ADT group were free of the primary endpoint (P = 0.002), implying an absolute risk difference of 26.6% (95% CI 10.0-43.3) in favour of CA. The proportion of patients free of any recurrence (>30 s) was higher in the CA group than in the ADT group (60.2 vs. 29.2%; P < 0.001) and cardioversion was less frequent (34.7 vs. 50%, respectively; P = 0.018).ConclusionCatheter ablation is superior to medical therapy for the maintenance of sinus rhythm in patients with persistent AF at 12-month follow-up.Clinical Trial Registration InformationNCT00863213 (http://clinicaltrials.gov/ct2/show/NCT00863213)

2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death the Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC) Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC)

N/

La partida de facciosos, que al mando del presbítero D. José Sarmiento asaltó ... la casa del Administrador de la Hacienda pública de Viana del Bollo, robandole los caudales ... ya no existe, pues alcanzada por la Milicia ... fue batida ... muerto seis hombres y hecho trece prisioneros, y quedando solo el cabecilla que se fugó ...

Precede ao título: Gobierno político superior de la provinciade [sic] LugoAo final do texto consta o nome do autor: Ángel del ArenalDatado en: Lugo 22 de Setiembre de 182

Gobierno politico de la Provincia de Lugo. El Sr. Gefe político de la Provincia de la Coruña ha dirigido á los Ayuntamientos una circular, señalando los derechos que deben exigirse por las conciliaciones, certificados y citaciones, y me le ha remitido por si juzgo que deba publicarse tambien en esta provincia. Considero que puede ser de la mayor utilidad el que llegue á noticia de todos, y con este objeto la inserto á continuacion ...

Apostila marxinal: Circular. Núm.º 7.º se hacen varias prevenciones sobre los derechos que deben pagarse por las conciliaciones, comparendos y otras diligenciasRespéctase a puntuación orixinalTexto asinado por Angel del ArenalTexto datado en: Lugo 17 de Abril de 1822Apostilas marxinai