Laparoscopic adrenalectomy for resection of unilateral noninvasive adrenal masses in dogs is associated with excellent outcomes in experienced centers

OBJECTIVE: To report the short- and long-term outcomes of laparoscopic adrenalectomy (LA) for resection of unilateral adrenal masses and to document risk factors for conversion and peri- and postoperative morbidity. ANIMALS: 255 client-owned dogs. METHODS: Dogs were included if LA was attempted for resection of a unilateral adrenal mass. Medical records were evaluated and relevant data were reported, including complications, conversion, perioperative death, and long-term outcomes. Signalment, clinicopathological data, and surgical experience were factors statistically evaluated for possible associations with capsular penetration during surgery, conversion, surgical time, duration of hospital stay, death prior to discharge, mass recurrence, and survival time. RESULTS: 155 dogs had left-sided tumors, and 100 had right-sided tumors. Conversion to an open approach was performed in 9.4% of cases. Capsular penetration (19.2%) and major hemorrhage (5.4%) were the most prevalent intraoperative complications. Of the dogs operated on, 94.9% were discharged from the hospital. Lesion side, portion of the gland affected, and surgeon experience influenced surgical time. Conversion rate increased with increasing body condition score and lesion size. Risk of death prior to discharge increased with increasing lesion size. Risk of conversion and death prior to discharge were lower when performed by more experienced surgeons. Capsular penetration during LA increased the risk of tumor recurrence. CLINICAL RELEVANCE: LA for resection of unilateral adrenal masses is associated with excellent outcomes in experienced centers. Surgeons with greater experience with LA have lower surgical times, conversion rates, and risk of death prior to discharge

Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network

Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

Dotación fonoaudiológica para la atención de pacientes adultos y pediátricos en hospitales chilenos de alta complejidad

Introduction: The Chilean Ministry of Health has developed a proposal to determine the number of professionals in health settings according to the number and type of clinical beds, for attending both hospitalised and ambulatory patients. That proposal differs with the international suggestions, which recommend one Speech Therapist per 10 clinical beds, or even more depending on each health institution. In Chile, there is just one study on this topic, which studied the number of Speech Therapists for attending hospitalised-adult patients in high-complex hospitals. Aim: To determine the Speech Therapists and the number of hours per week required for attending adults and paediatrics patients in Chilean high-complex hospitals. Methods: A descriptive, observational and transversal study was performed, including all the clinical beds available during 2022 in high-complex hospitals, for attending adults and paediatrics patients. Results: 64 high-complex hospitals were included. Of the total of Speech Therapists required, the Metropolitan region needs a 37,71%, then, the Valparaiso region a 9,60%, and the Bío-Bío region a 9,22%. 19,613.26 hours per week are required for attending both adults and paediatrics patients in high-complex hospitals. Conclusion: Considering the number and type of the clinical beds per hospital, a total of 504 Speech Therapists are required in Chile. Of them, 445 for a journey of 44 hours per week, 17 for 33 hours, 13 for 22 hours, and 29 for 11 hours. It is suggested to calculate the gap between the hours required per week per hospital, and the real contracted hours in health settings.El Ministerio de Salud en Chile ha realizado una propuesta para cálculo de profesionales según número y tipo de camas hospitalarias, tanto para la atención abierta y cerrada. Dicha propuesta difiere de las recomendaciones internacionales, donde se propone un fonoaudiólogo cada 10 camas, siendo aún mayor según cada Institución. En el país solo existe un estudio de dotación fonoaudiológica orientado a la población adulta en hospitales de alta complejidad. El objetivo fue estimar la cantidad de fonoaudiólogos y horas requeridas semanales para usuarios adultos y pediátricos en hospitales chilenos de alta complejidad. Se realizó un estudio descriptivo, observacional, de corte transversal, que incluyó todas las camas hospitalarias del año 2022 de centros de alta complejidad en el país, para la atención de pacientes adultos y pediátricos, excluyendo camas psiquiátricas, obstetricia, ginecología, socio-sanitarias y de pensionados. Se incluyeron 64 hospitales para el cálculo. La Región Metropolitana concentra el mayor requerimiento profesional (37,71%), seguida de la Región de Valparaíso (9,60%), y finalmente por la Región del Bío-Bío (9,22%). Se precisa un total de 19.613,26 horas semanales en los centros de alta complejidad del país, para conseguir dar cobertura a los usuarios adultos y pediátricos. Se concluye que, a nivel nacional y considerando cada hospital por separado, se requiere un total de 504 fonoaudiólogos. 445 profesionales en jornadas de 44 horas semanales, 17 en jornadas de 33 horas, 13 en jornadas de 22 horas y 29 en jornadas de 11 horas. Se sugiere realizar cálculo de la brecha profesional a nivel nacional

Evaluación de patrones motores básicos en niños y niñas entre 9 a 11 años con discapidad cognitiva y síndrome de Down

Tesis (Profesor de Educación Física, Licenciado en Educación)El presente trabajo, surge al constatar que en el contexto escolar el profesor y profesora de Educación Física se enfrenta muchas veces a alumnos y alumnas con Necesidades Educativas Especiales (NEE) , esto debido fundamentalmente a las políticas de inclusión implementadas a nivel mundial y nacional. Por este motivo, es necesario indagar diversas situaciones que pueden evidenciar y explorar el modo en que se produce el aprendizaje con estudiantes con estas características y cuál es el desarrollo motor de éstos. Es por ello que esta investigación se focaliza en investigar el nivel de adquisición de las habilidades motoras básicas de locomoción y manipulación en niños y niñas de 9 a 11 años con Síndrome de Down y Discapacidad Cognitiva, perecientes a los centros educacionales de educación especial , Los Lirios, Los Copihues, Nuevo Mundo y Fundación Complementa de la Región Metropolitana. De acuerdo a los objetivos de la investigación , es un estudio de tipo descriptivo-cuantitativo, dado que se pretende identificar y describir como se manifiesta el desarrollo de los patrones motores básicos en niños y niñas de 9 a 11 años con Discapacidad Cognitiva y Síndrome de Down. Para recoger las evidencias de la investigación se utilizará el test de Me Clenaghan , Bruce A. y Gallahue, D. (1985) que entrega información referida al nivel de adquisición de los patrones motores básicos. Uno de los principales resultados es que la diferencia entre los patrones motores de los alumnos con Discapacidad Cognitiva y Síndrome Down es significativo, por su hipotonicidad y su incompleta comprensión de las indicaciones para ejecutar lo que se les pide. Sin embargo, su característica no condiciona o afecta considerablemente su condición motriz

Search for intermediate-mass black hole binaries in the third observing run of Advanced LIGO and Advanced Virgo

International audienceIntermediate-mass black holes (IMBHs) span the approximate mass range 100−105 M⊙, between black holes (BHs) that formed by stellar collapse and the supermassive BHs at the centers of galaxies. Mergers of IMBH binaries are the most energetic gravitational-wave sources accessible by the terrestrial detector network. Searches of the first two observing runs of Advanced LIGO and Advanced Virgo did not yield any significant IMBH binary signals. In the third observing run (O3), the increased network sensitivity enabled the detection of GW190521, a signal consistent with a binary merger of mass ∼150 M⊙ providing direct evidence of IMBH formation. Here, we report on a dedicated search of O3 data for further IMBH binary mergers, combining both modeled (matched filter) and model-independent search methods. We find some marginal candidates, but none are sufficiently significant to indicate detection of further IMBH mergers. We quantify the sensitivity of the individual search methods and of the combined search using a suite of IMBH binary signals obtained via numerical relativity, including the effects of spins misaligned with the binary orbital axis, and present the resulting upper limits on astrophysical merger rates. Our most stringent limit is for equal mass and aligned spin BH binary of total mass 200 M⊙ and effective aligned spin 0.8 at 0.056 Gpc−3 yr−1 (90% confidence), a factor of 3.5 more constraining than previous LIGO-Virgo limits. We also update the estimated rate of mergers similar to GW190521 to 0.08 Gpc−3 yr−1.Key words: gravitational waves / stars: black holes / black hole physicsCorresponding author: W. Del Pozzo, e-mail: [email protected]† Deceased, August 2020