Conditioned reflex activity of rats at later periods after the end of flight aboard the Kosmos-605 biosatellite

The aftereffects of spaceflight on the higher nervous activity of rats were studied. A five lane maze with a feeding terminal was used to check such factors as transfer of experience, the habit and speed of reaching the goal in the maze, long term memory, and the dynamics of errors. During the 3rd-7th postflight week, functional disturbances in the rat HNA were manifested in the deterioration of the capacity for the transfer of experience and for locating the feeding compartment in the maze, thus indicating a general decrease of work capacity. The increased number of errors and failures pointed to exhaustion of higher nervous processes and to the weakened functional activity of the brain

Thermal Dileptons at LHC

We predict dilepton invariant-mass spectra for central 5.5 ATeV Pb-Pb collisions at LHC. Hadronic emission in the low-mass region is calculated using in-medium spectral functions of light vector mesons within hadronic many-body theory. In the intermediate-mass region thermal radiation from the Quark-Gluon Plasma, evaluated perturbatively with hard-thermal loop corrections, takes over. An important source over the entire mass range are decays of correlated open-charm hadrons, rendering the nuclear modification of charm and bottom spectra a critical ingredient.Comment: 2 pages, 2 figures, contributed to Workshop on Heavy Ion Collisions at the LHC: Last Call for Predictions, Geneva, Switzerland, 14 May - 8 Jun 2007 v2: acknowledgment include

Oxygen support of physical stress in perindopril-treated hypertensive patients

Aim. To study and assess, with spiroergometry method, main parameters of physical stress (PS) oxygen (O2) support in arterial hypertension (AH) patients receiving combined and monotherapy with an ACE inhibitor perindopril. Material and methods. The study included 30 patients (17 females, 13 males; mean age 55.1±8.4 years) with systolic blood pressure (SBP) 140-180 mm Hg, and diastolic blood pressure (DBP) 90-110 mm Hg. Mean AH duration was 5.4±2.2 years. Due to target organ damage, all participants had high cardiovascular event risk. Results. Twelve-week perindopril monotherapy resulted in BP normalization at rest and in PS, significant increase of anaerobic threshold and O 2 pulse, as well as in non-significant improvement of peak O2 consumption, maximal minute lung ventilation, and breath reserve. Combination of perindopril and nebivolol or indapamide resulted in improving of all PS O2 support parameters. Choosing antihypertensive therapy, individually achieved PS level should be taken into account: if maximal O 2 support levels are achieved in >50% of predicted PS, combined therapy with diuretics and beta-blockers is optimal. Conclusion. Perindopril as combined and monotherapy significantly improved PS O2 support parameters in patients with essential arterial hypertension