1,626 research outputs found
Out of necessity comes unbridled imagination for survival: contributive justice in Spanish libraries during economic crisis
The call for this journal issue notes that âsocial justice in LIS/services involves achieving action-oriented socially relevant outcomes via information-related work.â There is not a more fitting time and place for such action than in Spain, where the current economic crisis left more than 6 million (27 percent of the population) unemployed as of 2013. It is not just communities that are grappling with the pain of the economic downturn; libraries are also suffering from the crisis as a result of budget cuts due to reduced public funding. This article presents the case of Spanish academic and public libraries that have found solutions to keep themselves open, providing services vital to the economic and sociocultural needs of their communities. This case is an example of contributive justice, as evidenced in the actions taken by Spanish libraries and their communities as well as in the manner in which the research data were collected. Eight library-related actions were found: professional, community, social, political, digital, cultural/heritage, economic, and ontological. Despite economic hardships all around, these Spanish examples reveal the impact of libraries as social justice institutions, the role of librarians as agents of change, and the value of contributive and grassroots efforts when governments fail to provide. Moreover, these contributions to social justice illustrate actions appropriate to a contributive justice framework for libraries, as proposed in this article.published or submitted for publicatio
Multi-objective metaheuristics for preprocessing EEG data in brainâcomputer interfaces
In the ïŹeld of brainâcomputer interfaces, one of the main issues is to classify the electroencephalogram (EEG) accurately. EEG signals have a good temporal resolution, but a low spatial one. In this article, metaheuristics are used to compute spatial ïŹlters to improve the spatial resolution. Additionally, from a physiological point of view, not all frequency bands are equally relevant. Both spatial ïŹlters and relevant frequency bands are user-dependent. In this article a multi-objective formulation for spatial ïŹlter optimization and frequency-band selection is proposed. Several multi-objective metaheuristics have been tested for this purpose. The experimental results show, in general, that multi-objective algorithms are able to select a subset of the available frequency bands, while maintaining or improving the accuracy obtained with the whole set. Also, among the different metaheuristics tested, GDE3, which is based on differential evolution, is the most useful algorithm in this contextThis work has been funded by the Spanish Ministry of Science under contract TIN2008-06491-C04-03 (MSTAR project).Publicad
Microstructural Characterization of Silver Nanoparticles for Bioimaging Applications
Junta de AndalucĂa FQM-6615, PI0070, FQM31
EXPERIMENTAL AND COMPUTATIONAL STUDY ON THE BUBBLE BEHAVIOR IN A 3-D FLUIDIZED BED WITH A VERTICAL-AXIS, ROTATING DISTRIBUTOR
This work presents experimental measurements in a three-dimensional fluidized bed equipped with a novel vertical-axis, rotating distributor, together with two-fluid (Eulerian-Eulerian) CFD simulation results. The influence of the distributor rotation on the behavior of the bubbles in the experiments and in the CFD results is compared and critically analyzed
LabVIEW-based control and acquisition system for the dosimetric characterization of a silicon strip detector
Theaimofthisworkistopresentanewdataacquisition,control,andanalysissoftwaresystemwrittenin LabVIEW.Thissystemhasbeendesignedtoobtainthedosimetryofasiliconstripdetectorinpolyethylene. It allows the full automation of the experiments and data analysis required for the dosimetric characterization of silicon detectors. It becomes a useful tool that can be applied in the daily routine check of a beam accelerator.MINECO ICTI2013-2016/FPA2013-47327-C2-1-RMINECO ICTI2013-2016/FPA2014-53290-C2-2- PJunta de AndalucĂa P12-FQM-160
Stress compensation by gap monolayers for stacked InAs/GaAs quantum dots solar cells
In this work we report the stacking of 10 and 50 InAs quantum dots layers using 2 monolayers of GaP for stress compensation and a stack period of 18 nm on GaAs (001) substrates. Very good structural and optical quality is found in both samples. Vertical alignment of the dots is observed by transmission electron microscopy suggesting the existence of residual stress around them. Photocurrent measurements show light absorption up to 1.2 ÎŒm in the nanostructures together with a reduction in the blue response of the device. As a result of the phosphorus incorporation in the barriers, a very high thermal activation energy (431 meV) has also been obtained for the quantum dot emission
Development and characterization of an eggplant (Solanum melongena) doubled haploid population and a doubled haploid line with high androgenic response
[EN] We developed an eggplant doubled haploid (DH) population from a commercial hybrid through androgenesis in microspore culture. Morphological variation, reproductive ability and androgenic responsiveness were evaluated. The DH population showed segregation in vegetative traits related to leaf, flower and fruit, and in reproductive traits such as fruit and seed setting or germination rate. The DH population and subsequent generations also presented variation in the androgenic response, with null, low and high response lines. From this population, we were able to identify the first eggplant highly androgenic DH line (DH36), remarkably similar to the donor hybrid in terms of morphology and reproductive ability, but stably producing four times more calli than the hybrid. The segregating DH population is potentially useful for genetic studies and mapping of several traits, whereas the highly androgenic line DH36 may be used as a model line to facilitate the study of eggplant androgenesis and embryogenesis for both basic and applied research.We would like to thank the reviewers of this manuscript for their critical and helpful comments. This work was supported by Grant AGL2014-55177-R to JMSS from Spanish Ministerio de Economia y Competitividad (MINECO) jointly funded by FEDER. ARS is supported by a Predoctoral Fellowship from the FPI Program of Universitat Politecnica de Valencia.Rivas-Sendra, A.; Manuel Campos-Vega; Calabuig-Serna, A.; SeguĂ-Simarro, JM. (2017). Development and characterization of an eggplant (Solanum melongena) doubled haploid population and a doubled haploid line with high androgenic response. 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Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer
TRPM8 ion channels, the primary cold sensors
in humans, are activated by innocuous cooling (<28 °C) and
cooling compounds (menthol, icilin) and are implicated in
sensing unpleasant cold stimuli as well as in mammalian
thermoregulation. Overexpression of these thermoregulators in
prostate cancer and in other life-threatening tumors, along
with their contribution to an increasing number of pathological
conditions, opens a plethora of medicinal chemistry opportunities
to develop receptor modulators. This Perspective
seeks to describe current known modulators for this ion
channel because both agonists and antagonists may be useful
for the treatment of most TRPM8-mediated pathologies. We
primarily focus on SAR data for the different families of
compounds and the pharmacological properties of the most promising ligands. Furthermore, we also address the knowledge
about the channel structure, although still in its infancy, and the role of the TRPM8 protein signalplex to channel function and
dysfunction. We finally outline the potential future prospects of the challenging TRPM8 drug discovery fieldWe thank Gregorio FernaÌndez-Ballester for the figure of the
TRPM8 homology model. Funding from the Ministry of
Economy and Competitiveness (BFU 2012-39092-C02;
SAF2015-66275-C2-R) and the Generalitat Valenciana
(PROMETEO II/2014/011).Peer reviewe
ConstrucciĂłn y propiedades psicomĂ©tricas de la Escala de Ansiedad de Lima de 20 Ătems (EAL-20).
Objetivo: Seleccionar los Ătems mĂĄs representativos de una escala de ansiedad de 130 Ătems (Escala de Ansiedad de Lima, EAL-130) para hacer posible la construcciĂłn de una versiĂłn breve de 20 Ătems (EAL-20). MĂ©todos: A partir de los datos del estudio previo de validaciĂłn de la EAL-130 en 254 pacientes, se utilizĂł el mĂ©todo de anĂĄlisis de regresiĂłn mĂșltiple para identificar los Ătems que mejor predecĂan los puntajes totales de cada una de 5 subescalas correspondientes a 5 sĂndromes incluidos en la escala original (ansiedad psĂquica, sĂntomas fĂsicos, pĂĄnico, agorafobia y fobia social). Se condujo un anĂĄlisis factorial de matriz policĂłrica de la nueva escala asĂ generada (EAL-20). Resultados: La EAL-20 tuvo un alfa de Cronbach de 0,8885 y sus 20 Ătems cubrieron el 90,38% de la varianza del puntaje total de la EAL-130. En la EAL-20 se identificaron 4 factores correspondientes a ansiedad fĂsica, fobia social, ansiedad psĂquica y agorafobia. Con un punto de corte de â„ 10 se obtuvo un equilibrio entre sensibilidad y especificidad para la identificaciĂłn de un CGI-Sâ„ 4. Conclusiones: Los 20 Ătems seleccionados para la EAL-20 permiten evaluar 4 dimensiones de ansiedad, con una mĂnima pĂ©rdida de informaciĂłn respecto a la EAL-130; se sugiere usar un punto de corte â„ 10 como indicador de ansiedad moderada o de severidad mayor
Innervation of the Human Cavum Conchae and Auditory Canal: Anatomical Basis for Transcutaneous Auricular Nerve Stimulation
The innocuous transcutaneous stimulation of nerves supplying the outer ear has been demonstrated to be as effective as the invasive direct stimulation of the vagus nerve for the treatment of some neurological and nonneurological disturbances. Thus, the precise knowledge of external ear innervation is of maximal interest for the design of transcutaneous auricular nerve stimulation devices. We analyzed eleven outer ears, and the innervation was assessed by Massonâs trichrome staining, immunohistochemistry, or immunofluorescence (neurofilaments, S100 protein, and myelin-basic protein). In both the cavum conchae and the auditory canal, nerve profiles were identified between the cartilage and the skin and out of the cartilage. The density of nerves and of myelinated nerve fibers was higher out of the cartilage and in the auditory canal with respect to the cavum conchae. Moreover, the nerves were more numerous in the superior and posterior-inferior than in the anterior-inferior segments of the auditory canal. The present study established a precise nerve map of the human cavum conchae and the cartilaginous segment of the auditory canal demonstrating regional differences in the pattern of innervation of the human outer ear. These results may provide additional neuroanatomical basis for the accurate design of auricular transcutaneous nerve stimulation devices
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