2,407 research outputs found

    Teachers as educational change agents: what do we currently know? findings from a systematic review

    Get PDF
    Change agents are individuals who can successfully transform aspects of how organisations operate. In education, teachers as change agents are increasingly seen as vital to the successful operation of schools and self-improving school systems. To date, however, there has been no systematic investigation of the nature and role of teacher change agents. To address this knowledge gap, we undertook a systematic review into five key areas regarding teachers as change agents. After reviewing 70 outputs we found that current literature predominantly positions teacher change agents as the deliverers of top-down change, with the possibility of bottom-up educational reform currently neglected

    MicroR159 regulation of most conserved targets in Arabidopsis has negligible phenotypic effects

    Get PDF
    BACKGROUND A current challenge of microRNA (miRNA) research is the identification of biologically relevant miRNA:target gene relationships. In plants, high miRNA:target gene complementarity has enabled accurate target predictions, and slicing of target mRNAs has facilitated target validation through rapid amplification of 5' cDNA ends (5'-RACE) analysis. Together, these approaches have identified more than 20 targets potentially regulated by the deeply conserved miR159 family in Arabidopsis, including eight MYB genes with highly conserved miR159 target sites. However, genetic analysis has revealed the functional specificity of the major family members, miR159a and miR159b is limited to only two targets, MYB33 and MYB65. Here, we examine the functional role of miR159 regulation for the other potential MYB target genes. RESULTS For these target genes, functional analysis failed to identify miR159 regulation that resulted in any major phenotypic impact, either at the morphological or molecular level. This appears to be mainly due to the quiescent nature of the remaining family member, MIR159c. Although its expression overlaps in a temporal and spatial cell-specific manner with a subset of these targets in anthers, the abundance of miR159c is extremely low and concomitantly a mir159c mutant displays no anther defects. Examination of potential miR159c targets with conserved miR159 binding sites found neither their spatial or temporal expression domains appeared miR159 regulated, despite the detection of miR159-guided cleavage products by 5'-RACE. Moreover, expression of a miR159-resistant target (mMYB101) resulted predominantly in plants that are indistinguishable from wild type. Plants that displayed altered morphological phenotypes were found to be ectopically expressing the mMYB101 transgene, and hence were misrepresentative of the in vivo functional role of miR159. CONCLUSIONS This study presents a novel explanation for a paradox common to plant and animal miRNA systems, where among many potential miRNA-target relationships usually only a few appear physiologically relevant. The identification of a quiescent miR159c:target gene regulatory module in anthers provides a likely rationale for the presence of conserved miR159 binding sites in many targets for which miR159 regulation has no obvious functional role. Remnants from the demise of such modules may lead to an overestimation of miRNA regulatory complexity when investigated using bioinformatic, 5'-RACE or transgenic approaches.RSA was funded by an ANU postgraduate scholarship and by a CSIRO Emerging Science Initiative. JL is the recipient of an ANU international student postgraduate scholarship. This research was supported by an Australian Research Council grant DP0773270

    Eficiência de biossólidos na produção de azevém baseado no conteúdo de nitrogênio

    Get PDF
    Biossólidos têm sido citados como capazes de aumentar a produção de culturas e suprir nutrientes para plantas. Questões sanitárias e ambientais demandam que eles sejam estabilizados para que sejam usados na agricultura. Os efeitos dos processos de estabilização sobre as propriedades agronômicas de biossólidos não são completamente conhecidos, apesar de essenciais para o seu manejo. Baseado em um modelo equivalente à equação de Mitscherlich, este trabalho avaliou os efeitos dos processos mais comuns para a estabilização de lodos de esgotos (compostagem, caleação, secagem térmica e irradiação solar) sobre a eficiência agronômica de biossólidos na produção de Lolium perenne L. em um Esposossolo Carbico órtico arenoso e um Latossolo Vermelho perférrico argiloso, usando NH4H2PO4 como referência. Os processos de estabilização afetaram a eficiência agronômica do lodo de esgoto, sendo freqüentemente mais alta que o tratamento com NH4H2PO4 em um solo arenoso, e mais baixa que a referência em um solo argiloso. O lodo irradiado por sol mostrou a mais alta eficiência agronômica entre os biossólidos testados nos dois solos, e o azevém alcançou a produção de pico com a menor dose de aplicação. Os biossólidos puderam substituir fertilizantes e produzir mais matéria seca que o NH4H2PO4, a depender do tipo de biossólido e do solo.Biosolids have been reported to increase yields and supply plant nutrients. However, complying with health and environmental standards is necessary before applying biosolids to land. Thus, sludge stabilization is required to make biosolids safe enough for their agricultural use. Side effects of stabilization processes on agronomic features of sewage sludge are not quite known, although their understanding is essential for biosolids management. Based on a model equivalent to the Mitscherlich equation, effects of the most common processes for sludge stabilization were evaluated (composting, liming, heat-drying and solar irradiation) in relation to the agronomic effectiveness of biosolids to yield Lolium perenne L. on two tropical soils, with NH4H2PO4 as a reference. Sewage stabilization processes have affected the ability of biosolids to promote plant growth. Their effectiveness was usually higher than fertilizer in a Spodosol and lower in an Oxisol. Solar-irradiated sludge presented the highest effectiveness among the biosolids and reached peak yields at the lowest application rate independent on soil type. Biosolids could efficiently substitute fertilizers and even yield more plant dry matter than the NH4H2PO4 reference, depending on the biosolid and soil type

    Examining operational wastes within Greek banking operations

    Get PDF
    In order to address operational effectiveness in the banking sector caused by the 2008 global economic crisis, this study examines the nature of operational wastes that exist within four large Greek banks. A Delphi study was undertaken with ten managers and ten employees. The waste of underutilised people is found to be the dominant form of waste present and affecting the efficiency of banking operations. This has implications for managers of banking operations needing to address efficiencies in an increasingly competitive global economic environment. The paper also highlights the drawbacks of analysing typologies of waste across organisations and industrial sectors

    Hepatocyte growth factor regulates neovascularization in developing fat pads

    Get PDF
    In this study, we used lentiviral-delivered shRNA to generate a clonal line of 3T3-F442A preadipocytes with stable silencing of hepatocyte growth factor (HGF) expression and examined the long-term consequence of this modification on fat pad development. HGF mRNA expression was reduced 94%, and HGF secretion 79% (P < 0.01), compared with preadipocytes treated with nontargeting shRNA. Fat pads derived from HGF knockdown preadipocytes were significantly smaller (P < 0.01) than control pads beginning at 3 days postinjection (0.022 ± 0.003 vs. 0.037 ± 0.004 g), and further decreased in size at day 7 (0.015 ± 0.004 vs. 0.037 ± 0.003 g) and day 14 (0.008 ± 0.002 vs. 0.045 ± 0.007 g). Expression of the endothelial cell genes TIE1 and PECAM1 increased over time in control fat pads (1.6 ± 0.4 vs. 11.4 ± 1.7 relative units at day 3 and 14, respectively; P < 0.05) but not in HGF knockdown fat pads (1.1 ± 0.5 vs. 5.9 ± 2.2 relative units at day 3 and 14). Contiguous vascular structures were observed in control fat pads but were much less developed in HGF knockdown fat pads. Differentiation of preadipocytes to mature adipocytes was significantly attenuated in HGF knockdown fat pads. Fat pads derived from preadipocytes with knockdown of the HGF receptor c-MET were smaller than control pads at day 3 postinjection (0.034 ± 0.002 vs. 0.049 ± 0.004 g; P < 0.05), and remained the same size through day 14. c-MET knockdown fat pads developed a robust vasculature, and preadipocytes differentiated to mature adipocytes. Overall these data suggest that preadipocyte-secreted HGF is an important regulator of neovascularization in developing fat pads

    Exploring children's reactions to sponsorship transition: a study of interpersonal and pro-social demands

    Get PDF
    Purpose The purpose of this study is to evaluate children’s perceptions and attitudes towards sponsorship transition, specifically the change from Nike to PUMA as kit sponsors for Manchester City Football Club (MCFC) in July 2019. Design/methodology/approach A sample of 368 children, between 7 and 16 years of age were recruited for the study. Using electronic diaries, 1,577 diary entries were captured between February 2019 and March 2020. Findings Data reveals that children conceptualise sponsorship as a social exchange, with sponsoring brands seen as human entities and interaction with them reflecting the dynamism of social and familial relationships. Consequently, children in this study demanded prosocial and interpersonal behaviours from sponsors and sponsee during the transition period. Research limitations/implications The research has an immediate and direct application for brand managers and the sponsee when considering terminating long-term sponsorship. Both the departing and incoming sponsors can maximise their relationships with these younger fans through an orchestrated departure, arrival and dedicated handover. Practical implications The findings enable marketing brand managers to effectively evaluate sponsor transition to maximise opportunities to maintain, and indeed start, brand relationships with younger fans. Originality/value This is the first study that has examined sponsorship children’s responses to sponsorship transition

    Exploring the motivations to participate in an online brand community: a study of 7–11-year-old children

    Get PDF
    Purpose The purpose of this research is to understand what motivates 7–11-year-old children to participate in online brand communities (OBCs). Prior research has concentrated on prescriptive product categories (games and gaming), predominantly adolescent groups and the social aspects of community engagement and actual behaviour within communities, rather than the motivations to participate with the OBC. This has ultimately limited what has been gleaned, both theoretically and managerially, from this important segment. Design/methodology/approach An interpretive, longitudinal position is adopted, using a sample of 261 children (113 male and 148 female) from across the UK, using event-based diaries over a 12-month period, generating 2,224 entries. Findings Data indicate that children are motivated to participate in a brand community for four reasons: to support and ameliorate pre-purchase anxieties, resolve interpersonal conflicts, exact social dominance in terms of product ownership and perceptions of product knowledge and to actively engage in digitalised pester power. The study also reveals that certain motivational aspects such as conflict resolution and exacting dominance, are gender-specific. Research limitations/implications Knowledge of children’s motivation to engage with OBCs is important for marketers and brand managers alike as the data reveal markedly different stimuli when compared to known adult behaviours in the field. Given the nature of the study, scope exists for significant future research. Practical implications The study reveals behaviours that will assist brand managers in further understanding the complex and untraditional relationships that children have with brands and OBCs. Originality/value This study makes a novel examination of a hitherto little-explored segment of consumers. In doing so, it uncovers the theoretical and practical characteristics of child consumers that contemporary, adult-focussed literature does not recognise. The paper makes an additional contribution to theory by positing four new behavioural categories relating to community engagement – dependers, defusers, demanders and dominators – and four new motivational factors which are fundamentally different from adult taxonomies – social hegemony, parental persuasion, dilemma solving and conflict resolution

    What are the social and personal drivers to engage in co-creation? A study of UK 7–13-year-olds

    Get PDF
    Purpose: The purpose of this paper is to explore the social and personal drivers of co-creation in children. Design/methodology/approach: A sample of 463 children aged between 7 and 13 years were recruited. Using electronic event-based diaries, 2,631 entries were captured during an 18-month period. Findings: Data from 861 entries identified a series of anomalous external social and personal factors that drove children to engage in co-creation. These were for maintaining external relationships, dealing with addiction to the co-creation process and dealing with personal loneliness. Research limitations/implications: The study reveals new, unconventional and gender-specific behaviours that might assist marketers in understanding children’s complex relationships with co-creation and brands. Originality/value: To the best of the authors’ knowledge, this is the first study of its kind to examine children’s social and personal drives to engage in co-creation

    Experiencing the Macromarketing Dimensions of Sustainability:Lessons Learned from Field Trips to the Ultra Novel

    Get PDF
    This paper seeks to determine the value of field trips that help establish macromarketing and sustainability scholarship in mainstream business/marketing education. It explores the experiences of postgraduate marketing and business strategy students undertaking a field trip to the “World’s Greenest Football Club,” Forest Green Rovers. It responds to the call to establish the macromarketing viewpoint within business and management education and provides contemporary insight into the hitherto unexplored use of field trips for postgraduate students. Through student focus groups the study identifies the importance of selecting field trip locations where the complex and interwoven interplay of meso, micro, and macro activities can be critically evaluated through multiple stakeholder interactions. In addition, it points to the value of students experiencing “ultra-novel” organizations and situations to motivate learning, stimulate critical debate, and thereby facilitate cognition of macromarketing systems and sustainability

    Antecedents of cybersecurity implementation: a study of the cyber-preparedness of U.K. social enterprises

    Get PDF
    The cyber-security of organisations is a subject of perennial concern as they are subject to mounting threats in an increasingly digitalised world. While commercial and charitable organizations have been the objects of cyber security research, Social Enterprises have remained unexplored. As Social Enterprises have become increasingly important features of social and economic development, so their prominence as potential targets of cybercrime also increases. In order to address this knowledge gap, this study examines the factors that influence the cyber-preparedness of Social Enterprises in the UK. Through the use of semi-structured interviews with Social Enterprise, these factors are found to comprise the characteristics of the enterprise, the characteristics of the enterprise management, resource constraints, experience of cyber attacks, usage of IT, and awareness of cybersecurity schemes and resources. These insights provide valuable guidance for SE owner-managers, SE support agencies and policy-makers when considering the cyber security of SEs. These findings are of immediate concern to social enterprises but also to other organizations that are engaged in partnerships with them as social enterprises may afford ‘gateway’ opportunities to those with malicious intent
    corecore