244 research outputs found

    New Self-Sufficient Shelter Solutions for Big Cities’ Collapsed Rental Markets

    Get PDF
    Nowadays, there is a wide variety of problems in the big cities related to the urban frame and to housing. Architects have to provide solutions that not only improve people’s well-being but also have to be efficient during the building’s entire life cycle. Within the European context, big cities like Paris, Berlin and Amsterdam have a huge demand for housing coming mainly from two different groups: people looking for temporary shelter and people looking for a more stable situation. In both cases, the need for new housing have resulted in inefficient urban developments, collapsed city centres and developed satellite cities where low and medium class people have tried to find somewhere to live, running away from infra-housing. In Paris, urban regulations set the minimum area for a rented apartment as 10m2. The research described in this paper analyzes the current situation in big cities from two points of view: apartment sizes and medium fees for temporary shelter. It defines the average architectural conditions of the “affordable” shelter and with this data; an experimental approach for a new completely self-sufficient housing module is provided, placed in a worthless space of existing buildings (roofs). This new module is defined by its sustainability and self-sufficiency and it gives the rental market an opportunity to increase the offer of shelter to rent in the big cities. At the end of the research, the development of an analysis of life cost cycle of the new module shows it as an alternative to the existing examples of infra housing with very short periods for recovering the investment

    Water flows through mussel rafts and their relationship with wind speed in a coastal embayment (Ría de Ares-Betanzos, NW Spain)

    Get PDF
    14 páginas, 4 tablas, 8 figurasKnowledge of water flows through mussel rafts and their controlling factors is required for an ecosystem approach to the sustainable management of this culture in the Galician rías. With this aim, 4 acoustic 2D-ACM current meters were hung from the bow of 4 rafts located in the mussel cultivation areas of the Ría de Ares-Betanzos (NW Spain) during autumn 2007. Simultaneously, an Aanderaa DCM12 Doppler profiler was moored in an area free of rafts in the middle ría. There were differences in the subtidal and tidal dynamics of the middle channel and mussel farm areas. The tide explained 51.5% of the total variance of the surface current in the middle ría. The explained variance in the seed collection areas of Redes (inner ría) and Miranda (outer ría), where only 2–3 rafts are anchored, were 64.1% and 16.8%, respectively. In the cultivation areas of Arnela (inner ría) and Lorbé (middle ría), where 101 and 40 rafts are anchored, 14.3% and 53.4% of the total variance was explained by the tide. These disparities in the contribution of the tide are likely due to a combination of topographic and bathymetric differences among sites and distortions of the natural flow by the rafts and their hanging ropes. Furthermore, there was a marked influence of winds on the subtidal currents within the rafts; contrasting correlation coefficients and lag times between wind speed and currents were observed for the outer and inner sides of the embayment. The filtration rate of the growing mussels and the number of mussels per raft allow an efficient clearing of the particles transported across the hanging ropes by the measured subtidal currents of 2–3 cm s–1 characteristic of the cultivation areas of Arnela and LorbéPROINSA Mussel Farm, codes CSIC20061089 and 0704101100001Xunta de Galicia PGIDIT06RMA018E and PGIDIT09MMA038EESSMA project Spain–Canada Grant of MICINNPeer reviewe

    Análisis geoambiental en medios hipogeos

    Get PDF
    8 páginas, 1 figura. Ed. Miguel Ángel Rogerio Candelera y Cesáreo Sáiz Jiménez. Primera Reunión de la Red de Ciencia y Tecnología para la Conservación del Patrimonio (Madrid, 28-29 de junio de 2011).Los coordinadores de los dos grupos de trabajo localizados actualmente en dos instituciones independientes (CSIC, Universidad de Alicante) se iniciaron científica y profesionalmente en el equipo de investigación de Geología - Geoquímica - Microclima aplicados a la Conservación del Patrimonio que se formó bajo la dirección de Manuel Hoyos Gómez a principios de la década de los 90. En el campo de la Conservación del Patrimonio, las investigaciones de ese grupo se centraron especialmente en la protección del arte rupestre y actualmente se enfocan al estudio integrado de ambientes subterráneos (cuevas, catacumbas,túneles, etc.) y de los procesos de deterioro del patrimonio que albergan. Los proyectos en los que los dos grupos trabajan abitualmente en estrecha relación incluyen datos de los parámetros climáticos y microclimáticos que caracterizan los sitios de estudio, de las características mineralógicas, geoquímicas y petrofísicas de los soportes y de las aguas de infiltración, y de los aspectos geomicrobiológicos de la interacción entre microoorganismos y los diferentes sustratos existentes (rocas, materiales de construcción, espeleotemas, etc.).Peer reviewe

    Insemination extender supplementation with bestatin and EDTA has no effect on rabbit reproductive performance

    Full text link
    [EN] The addition of aminopeptidase inhibitors (AMIs) to rabbit semen extenders could be a solution to decrease the hormone degradation (GnRH) by the aminopeptidases existing in the seminal plasma. Therefore, the quantity of GnRH needed to induce ovulation in doe would be comparable with the amount administered intramuscularly (i.m.). This study was conducted to evaluate the effects of two AMIs (bestatin and EDTA) on rabbit semen quality parameters, beta nerve growth factor ((beta-NGF) degradation and reproductive performance after artificial insemination. Results showed that seminal quality was not affected by the incubation with AMIs; the values of motility, acrosome integrity and sperm viability were not significantly different between the AMIs and the control groups (positive i.m. and negative intravaginally without AMIs). In addition, the aminopeptidase activity of seminal plasma was inhibited in a 55.5% by the AMIs as well as beta-NGF degradation. On the other hand, regarding the effect of AMIs on reproductive performance, our results showed that the presence of bestatin and EDTA did neither affect fertility (85.3 vs. 88.6%), nor the prolificacy rate (10.12 vs. 10.51 kits per delivery), comparing AMIs group to positive control group, respectively. We conclude that the addition of specific AMIs in the rabbit semen extender has no effect on reproductive performance. Therefore, due to the fact that AMIs inhibit part of the aminopeptidase activity that degrades the GnRH analogue and beta-NGF, they could be used to develop new extenders with less hormone concentration. (C) 2017 Elsevier Inc. All rights reserved.This research was supported in part by the RTA2013-00058-00-00 from INIA, the European Social Fund and the European FEDER Funds. L. Casares-Crespo is supported by a scholarship from Instituto Valenciano de Investigaciones Agrarias (IVIA) and the European Social Fund. P. Fernandez-Serrano is supported by funds from Instituto Valenciano de Investigaciones Agrarias (IVIA) and Ministerio de Empleo y Seguridad Social (Programa de Garantia Juvenil).Casares-Crespo, L.; Fernández-Serrano, P.; Vicente Antón, JS.; Moce Cervera, ET.; Castellini, C.; Stabile, A.; Viudes De Castro, MP. (2018). Insemination extender supplementation with bestatin and EDTA has no effect on rabbit reproductive performance. Theriogenology. 105:61-65. https://doi.org/10.1016/j.theriogenology.2017.09.009S616510

    Bacterioplankton responses to riverine and atmospheric inputs in a coastal upwelling system (Ría de Vigo, NW Spain)

    Get PDF
    Original research paperAnthropogenic pressures are changing the magnitude and nature of matter inputs into the ocean. The Ría de Vigo (NW Spain) is a highly productive and dynamic coastal system that is likely affected by such alterations. Previous nutrient-addition microcosm experiments conducted during contrasting hydrographic conditions suggested that heterotrophic bacteria are limited by organic carbon (C) and occasionally co-limited by inorganic nutrients in this coastal area. In order to assess short-term responses in biomass, production, and respiration of heterotrophic bacteria from the Ría de Vigo to increasing amounts of natural inputs of matter, we conducted 6 microcosm experiments, wherein surface seawater collected in spring, summer, and autumn was mixed with increasing amounts of dissolved natural matter concentrates from riverine and atmospheric origin. Simultaneous experiments with controlled inorganic and/or organic additions indicated that bacteria were co-limited by inorganic nutrients and C in spring and summer and primarily limited by C in autumn. Production responded more than biomass to increasing inputs of matter, whereas respiration did not change. The bacterial production response to increasing dissolved organic C load associated with riverine and atmospheric inputs was strongly related to the relative phosphorus (P) content of the dissolved matter concentrates. Our data suggest that bacterial production might decrease with the increase of P-deficient allochthonous matter inputs, which would have important biogeochemical consequences for C cycling in coastal areas.Spanish Ministry of Science and Innovation, MINECO, CSIC, Xunta of Galicia and European Union (Marie Curie Grants)Versión del edito

    A new scenario in metastatic renal cell carcinoma: a SOG‑GU consensus

    Get PDF
    [Abstract] Background This article describes and compares approved targeted therapies and the newer immunotherapy agents. Materials and methods This article especially performs an in-depth review of currently available data for tivozanib, explaining its mechanism of action, its safety profle and its role as an efcacy drug in the management of renal cancer. Results Despite the fact that the treatment of advanced RCC has been dramatically modifed in recent years, durable remissions are scarce and it remains a lethal disease. For frst- and second-line therapy, there is now growing evidence to guide the selection of the appropriate treatment. Conclusions Several TKIs are standard of care at diferent settings. Among those approved TKIs, tivozanib has similar efcacy than others with a better safety profle. The use of prognostic factors is critical to the selection of optimal therapy

    Ageism and nursing students, past or reality?: a systematic review

    Get PDF
    Objective: This systematic review aimed to summarise and update existing knowledge about ageism among nursing students through the following research question: what is the perception and attitudes of ageism among student nurses? Design: A systematic review of longitudinal and cross-sectional studies of ageism in nursing students was carried out. Data sources: The literature search was conducted in the scientific databases Pubmed and Scopus in February 2021. Review methods: After the screening process, 22 studies meeting the selection criteria were selected; 8 more were identified after manually searching the selected paper' reference lists. A total of 30 studies were included in the review. The JBI Critical Appraisal Checklists for Analytical Cross-Sectional studies and for Cohort Studies were used to appraise the articles' quality. Results: There was large variability in the manifestation of ageism among student nurses, as well as in the instruments used for assessment. Most of the articles analysed attitudes towards old age, the majority of which were positive. Being a female student, being on the final year of study and having regular contact or cohabitation with an older adult were three of the main determinants in the expression of positive attitudes towards the elderly. Conclusions: Our findings suggest that student nurses generally have positive attitudes towards old age, although ageist beliefs and discriminatory behaviours were identified and should be studied in greater depth. Training programs for future care professionals have a responsibility to educate from a non-stereotypical perspective based on current societal needs

    Changes in the CO2 dynamics in near-surface cavities under a future warming scenario: Factors and evidence from the field and experimental findings

    Get PDF
    This study is based on field monitoring of a cave-soil-atmosphere system validated with laboratory experiments. CO2 and 222Rn dynamics in the cavity are dependent on climatic parameters, mainly on the differences between the outdoor and indoor temperature. The annual cycles in the cave are characterized by two outstanding phenomena: cave gas recharge and ventilation when the cave acts as a gas sink or source. A permanent relationship with soil above the cave exists. The soil temperature and moisture are responsible for CO2 production on various time scales. Soil CO2 at the Rull site reaches values higher than 3000 ppm in April–May, but falls to nearly 1000 ppm during the summer. Maximum CO2 values in the cave are reached in the warmest months and are in accordance with soil CO2 values. The maximum CO2 concentration in the cave is 3470 ppm on average, while the minimum is 623 ppm. To describe the field findings, CO2 production and diffusion experiments related to the soil behaviour were developed. The results show that the soil CO2 production increases as the soil temperature and moisture increase according to a calculated logarithmic equation until the soil water content exceeds the saturation value. The soil-produced CO2 reaches the Rull cave by diffusion, which in Rull soil is reduced to approximately 60% when the soil water content increased from 0 to 30%. We estimated that 57 kg of CO2 was emitted from the cave to the atmosphere in an annual cycle, considering a cave volume of 9915 m3. Finally, projections of the future climate at the study site confirm a general tendency for annual-mean conditions to be warmer and drier, which will directly affect the soil CO2 production. In this situation, the Rull cave will experience changes in the stored and subsequently exchanged annual amount of CO2.This research was funded by the Spanish Ministry of Economy and Competitiveness projects CGL2011-25162 and CGL2013-43324-R and its programme Torres Quevedo (PTQ 13-06296 and PTQ 12-05601). A pre-doctoral research fellowship (BES-2012-053468) was awarded to C. Pla for the project CGL2011-25162. Funding was also provided by the People Programme (Marie Curie Actions—Intra-European Fellowships, call 2013) of the European Union Seventh Framework Programme (FP7/2007-2013) under the REA grant agreement n624204

    Abiotic and seasonal control of soil-produced CO2 efflux in karstic ecosystems located in Oceanic and Mediterranean climates

    Get PDF
    This study characterizes the processes involved in seasonal CO2 exchange between soils and shallow underground systems and explores the contribution of the different biotic and abiotic sources as a function of changing weather conditions. We spatially and temporally investigated five karstic caves across the Iberian Peninsula, which presented different microclimatic, geologic and geomorphologic features. The locations present Mediterranean and Oceanic climates. Spot air sampling of CO2 (g) and δ13CO2 in the caves, soils and outside atmospheric air was periodically conducted. The isotopic ratio of the source contribution enhancing the CO2 concentration was calculated using the Keeling model. We compared the isotopic ratio of the source in the soil (δ13Cs–soil) with that in the soil-underground system (δ13Cs–system). Although the studied field sites have different features, we found common seasonal trends in their values, which suggests a climatic control over the soil air CO2 and the δ13CO2 of the sources of CO2 in the soil (δ13Cs–soil) and the system (δ13Cs–system). The roots respiration and soil organic matter degradation are the main source of CO2 in underground environments, and the inlet of the gas is mainly driven by diffusion and advection. Drier and warmer conditions enhance soil-exterior CO2 interchange, reducing the CO2 concentration and increasing the δ13CO2 of the soil air. Moreover, the isotopic ratio of the source of CO2 in both the soil and the system tends to heavier values throughout the dry and warm season. We conclude that seasonal variations of soil CO2 concentration and its 13C/12C isotopic ratio are mainly regulated by thermo-hygrometric conditions. In cold and wet seasons, the increase of soil moisture reduces soil diffusivity and allows the storage of CO2 in the subsoil. During dry and warm seasons, the evaporation of soil water favours diffusive and advective transport of soil-derived CO2 to the atmosphere. The soil CO2 diffusion is enough important during this season to modify the isotopic ratio of soil produced CO2 (3–6‰ heavier). Drought induces release of CO2 with an isotopic ratio heavier than produced by organic sources. Consequently, climatic conditions drive abiotic processes that turn regulate a seasonal storage of soil-produced CO2 within soil and underground systems. The results here obtained imply that abiotic emissions of soil-produced CO2 must be an inherent consequence of droughts, which intensification has been forecasted at global scale in the next 100 years.This research was funded by the Spanish Ministry of Economy and Competitiveness projects CGL2016-78318-C2-1R and CGL2016-78318-C2-2R AEI/FEDER/UE and its programme Torres Quevedo (PTQ 13-06296). Funding was also provided by the People Programme (Marie Curie Actions-Intra-European Fellowships, call 2013) of the European Union's Seventh Framework Programme (FP7/2007-2013) under the REA grant agreement nº 624204

    Consensus document on allergic conjunctivitis (DECA)

    Get PDF
    Allergic conjunctivitis (AC) is an inflammatory disease of the conjunctiva caused mainly by an IgE-mediated mechanism. It is the most common type of ocular allergy. Despite being the most benign form of conjunctivitis, AC has a considerable effect on patient quality of life, reduces work productivity, and increases health care costs. No consensus has been reached on its classification, diagnosis, or treatment. Consequently, the literature provides little information on its natural history, epidemiological data are scarce, and it is often difficult to ascertain its true morbidity. The main objective of the Consensus Document on Allergic Conjunctivitis (Documento dE Consenso sobre Conjuntivitis Alérgica [DECA]), which was drafted by an expert panel from the Spanish Society of Allergology and Spanish Society of Ophthalmology, was to reach agreement on basic criteria that could prove useful for both specialists and primary care physicians and facilitate the diagnosis, classification, and treatment of AC. This document is the first of its kind to describe and analyze aspects of AC that could make it possible to control symptoms
    corecore