9 research outputs found
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
- Bonnin David
- Border Richard
- Borowsky Mark
- Borzym Katja
- Boukhgalter Boris
- Bowen Eric
- Bradley Amanda
- Bradshaw-Cordum Holly
- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
- Branscomb Elbert
- Bray Jason
- Bray-Allen Sarah
- Brettin Thomas
- Bridgeman Anne
- Bridgers Michael
- Brimhall Angela K.
- Brokstein Peter
- Brook Jonathan
- Brooking Shane
- Brottier Philippe
- Brown Andrew
- Brown Clive
- Brown Jacqui
- Brown Margaret
- Brown Mary
- Brown Mary J.
- Brown Michael
- Brown Nancy C.
- Bruce David D.
- Bruce Robert
- Bruno William J.
- Bruskiewich Richard
- Bryant Jackie
- Bryant Jennifer E.
- Bryant Nathaniel P.
- Brüls Thomas
- Buatsi Delali
- Buck David
- Buckingham Judith M.
- Buckle Veronica
- Buczek Donald
- Budd Claire
- Buhay Christian J.
- Bulbul Kerem
- Buller Sarah
- Bunker Nathan
- Burberry Jill
- Burch Paula Ellen
- Burford Deborah
- Burgess Joanne
- Burgin Matt
- Burkett Carrie E.
- Burkhart-Schultz Karolyn
- Burrell Kevin L.
- Burrill Wayne
- Burrows Christine
- Burton Christine
- Burton John
- Butcher Phil
- Butler Adam
- Butler Jon
- Butler Paul
- Caenepeel Sean
- Cahill Patrick
- Cai Tianjing
- Cai Zhen
- Cairns Murray
- Calderon Eliana
- Callen David F.
- Camarata Jody
- Camire David
- Camm Nick
- Campbell Christopher
- Campbell Connie S.
- Campbell Evelyn W.
- Campbell Mary I.
- Campbell Mary L.
- Campo Kevin
- Canning Bruno
- Cao Ting
- Cao Yuzhu
- Caoile Chenier
- Cardenas Faviola
- Cardenas Lolo
- Cardenas Veronica
- Carder Carol
- Carder Paul
- Carpenter Kelly
- Carrano Anthony V.
- Carriere Jason
- Carter Jason
- Carter Kelvin
- Carter Nigel
- Caruso Lauren
- Casias Kristal
- Cattolico Laurence
- Cavanna Tamara
- Cavazos Iracema
- Cavazos Sandra R.
- Ceasar Heather
- Cedroni Maria
- Cepeda Mario
- Chacko Joseph
- Chain Patrick
- Chalk Shani
- Challacombe Jean F.
- Chan Ka
- Chan Sheryl N.
- Chan Yee Man
- Chang Jean L.
- Chapman Jarrod
- Chapman Joanna
- Chapple Jeffrey
- Charles Rachel
- Chasteen Leslie A.
- Chavarria Simeon
- Chazaro Bruno
- Chen Baoxian
- Chen Bin
- Chen Chira
- Chen Chong
- Chen Chong
- Chen Chun-Nan
- Chen Cong
- Chen Ellson
- Chen Hsiu-Chuan
- Chen Jianlong
- Chen Jie
- Chen Jin
- Chen Junbao
- Chen Lihong
- Chen Lixia
- Chen Ray
- Chen Shu
- Chen Tong
- Chen Xiaoyun
- Chen Xinyi
- Chen Yanjiong
- Chen Yiyu
- Chen Zhu
- Chen Zhu
- Chen Zhu
- Cheng Jan-Fang
- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
- Chinn Corey
- Chinwalla Asif
- Chissoe Stephanie
- Chiu Sally
- Chothia Tom
- Christensen Mari
- Christopoulos Constantine
- Chu Joseph
- Chui Connie
- Chung A
- Cinkowsky Michael J.
- Citroen Mieke
- Clack Rob
- Clamp Michele
- Clark Anthea
- Clark Graham
- Clark Kevin
- Clark Lynn
- Clark Lynn M.
- Clark Richard
- Clark Sarah
- Clark Sue
- Clarke Adrian
- Clarke Betty
- Clarke Eddie
- Clarke Kay
- Clarke Laura
- Clawson Hiram
- Clee Chris
- Clegg Shelia
- Clerc Blankenburg Kerstin Petra
- Cleveland David
- Clifford Karen
- Clifton Sandra W.
- Coates Julia
- Cobley Victoria
- Cockrell Raynard
- Coffey Alison
- Cofield Jackie
- Coggill Penelope
- Cohn Judith D.
- Colayco Rick
- Cole Lotte
- Collier Rachael
- Collings Simon
- Collins Francis S.
- Collins John
- Collins Philip
- Collymore Al
- Colman Louise
- Combs Jessie
- Comstock Robin
- Cong Bin
- Conner Richard
- Connolly Anthony
- Connolly Karen
- Conquer Jennie
- Conrad Ansgar
- Conroy Donald
- Considine Tony
- Constance Doug
- Cook April
- Cook Leanna
- Cooke Patrick
- Cooper Jonathan
- Cooper Rachel
- Cooper Robert
- Copeland Alex
- Coppola Maria
- Copsey Teresa
- Corby Nicole
- Cordes Matt
- Cordray Rebecca
- Cornell Christine
- Cornell Earl
- Cornell Linda
- Cornell Ruth
- Corum Ben
- Cottage Amanda
- Cotton Sara
- Coulson Alan
- Couronne Olivier
- Courtney Laura P.
- Coville Gez
- Cox Anthony
- Cox Caroline D.
- Cox Tony
- Coxhill Robert
- Coyle Marcus D.
- Craig Matthew
- Crane Tom
- Crawford Amanda L.
- Crawley Matt
- Cree Andrew
- Crespeau Hervé
- Crew Victor
- Critchlow Terrance
- Critz Paul
- Cruaud Corinne
- Cuff James
- Cui Hongjuan
- Cui Jinhui
- Cui Peng
- Cui Peng
- Culley Karl
- Cummings Auli
- Cummings Kirsti
- Cummings Paul
- Cummings Stephanie
- Cuomo Christina A.
- Curran Adam
- Curwen Valery
- Cutts Jeffrey
- Czubayko Martin
- D\u27Souza Lisa Marie
- Da Silva Corinne
- Dai Li
- Dalin Eillen
- Dang Michelle
- Danganan Linda
- Daniels Rachael
- Dathorne Stephanie R.
- Daum Christopher
- David Robert
- Davidson Lucy
- Davidson Stuart
- Davies Jonathon
- Davies Joy
- Davies Nicholas
- Davies Robert
- Davila Mary Louise
- Davis Candi Mon\u27et
- Davis Cheryl
- Davis Clay
- Davis Jayne
- Davis John
- Davis Matthew
- Davy-Carroll Latarsha
- Dawoe Tenzin
- Dawson Elisabeth
- De Anda Claudia
- De Latorre Andrea
- Deadman Rebecca
- Dean Peter
- Dear Simon
- Dearden Frances
- DeArellano Kurt
- Deaven Larry I.
- Deaven Larry L.
- Deere Kerry
- DeGray Stewart
- Degusta David
- Deguzman Maria
- Dehal Paramvir
- Delgado Marcos
- Delgado Oliver
- Delhaunty Kimberley
- Deloukas Panos
- Deng Yajun
- Dennis Janet
- Denson Shawn
- Denys Mirian
- Deramo Christine
- Desai Anu
- Detter John C.
- Devlin Laurie
- Dewar Ken
- Dhami Pawandeep
- Dhongsar Chemey
- Dias Jennifer
- Dias Victoria
- Dibartolo Genevieve
- Dibling Catherine
- Dickson Mark
- Diekhans Mark
- Dietz-Band Jeanne
- Digennaro Richard
- Dilts Karen
- Dimitrijevic-Bussod Mira
- Ding Hao
- Ding Keyue
- Ding Li
- Ding Yan
- Dinh Huyen H.
- Dixon Kami
- Do Long
- Dobbs Ruth
- Dobson Richard
- Dockree Catherine
- Doddington Daniel
- Dodsworth Steven
- Doggett Norman
- Doggett Norman A.
- Dong Hui
- Dong Kimberly
- Dong Wei
- Dong Wei
- Dong Xiaojia
- Donlin Jeremy E.
- Dooley Kathy
- Dooling David
- Dorje Passang
- Dorjee Kunsang
- Dorris Lester
- Dorsett Victor
- Doucette-Stamm Lynn
- Douthwaite Karen J.
- Down Thomas
- Draper Heather
- Du Feiyu
- Du Hui
- Du Yutao
- Duarte Suzanne
- Dubchak Inna
- Duffy Noah
- Dugan-Rocha Shannon
- Dunham Andrew
- Dunham Ian
- Dunn Adam M.
- Dunn Anne
- Dunn Matthew
- Dunwell Erin
- Dupes Alan
- Durbin Kenneth J.
- Durbin Richard
- Durham Jillian
- Dutta Ireena
- Dwyer Ruth
- Dyer Lauren
- Dziuda Darius
- Earnhardt Christopher D.
- Earthrowl Mark
- Eastham Emma
- Eastham Timothy
- Eaves Kristy A.
- Eckenberg Ralph
- Edgar Darren
- Edionwe Susan Omwanghe Osayanro
- Edwards Carol
- Edwards Jennifer
- Edwards Karen
- Egan Amy
- Eichler Evan
- Eichler Evan
- Ejima Fumio
- Elkin Chris
- Ellington Andrew
- Elliot David
- Elliot Glendoria
- Elliot Jeffrey
- Ellwood Matthew
- Emberson Becky
- Emelianenko Natalia
- Emery-Cohen Alexandra J.
- Endrizzi Matthew
- Engh Ger van den
- Engle David
- Erickson Jeffery
- Erler Anne Marie
- Errington Helen
- Escobar Julio
- Escotto Michael
- Eugene Craig S.
- Evans Gareth
- Evans John
- Evans Katie
- Evans Richard
- Eveleth Gerald
- Eyras Eduardo
- Fan Hongyuan
- Fan Keke
- Fang Jianqiu
- Farina Abderrahim
- Faro Susan
- Faulkner Louisa
- Fawcett Joseph J.
- Fechtel Kim
- Fellingham Charlotte
- Felming Claire
- Felsenfeld Adam
- Feltwell Theresa
- Feng Guodong
- Feng Haiyan
- Feng Jie
- Feng Xiaoli
- Fennell Stephen
- Ferguson Alicia
- Fernandez Sonia
- Fernandez-Suarez Xose
- Fernando Pushpa Ranjani
- Ferriera Pat
- Fertitta Anne
- Fey Jim
- Fidel Patrick
- Fields Elizabeth
- Fink Marie
- Finley Maria C.
- Finn Robert
- Fischer Heather
- Fischer Laurice
- Fisher Shelia
- Fitch Pat
- Fitzgerald Mike
- Flack Tina
- Flagg Nicole
- Flanagan J.
- Fleming Kerry
- Flint Jonathan
- Flint Mark
- Flowers Dave
- Floyd Yvonne
- Foley Karen
- Folta Peg
- Fong Jonathan
- Fonknechten Núrua
- Footman Simon
- Forbes Lisa D.
- Ford Amanda F.
- Foster Myre J.
- Fotopulos Dea
- Fourcade Matthew
- Fowler John
- Fox Jessica
- Frame Deborah
- Francis Matthew
- Francis Stephen
- Frankel Ken
- Frankish Adam
- Frankland John
- Fraser Audrey
- Fraser David
- Frazier Marvin
- French Lisa
- Fricker David
- Fridlyand Jane
- Fronick Catrina
- Frost Carole
- Frost Daniel
- Frost Jackie
- Frost Lorna
- Fu Gang
- Fu Gang
- Fu Gang
- Fu Qiushi
- Fujioka Michiru
- Fujiyama Asao
- Fukawa Rintaro
- Fuller Liam
- Fuller Sharin
- Fullerton Kathryn
- Fulton Lucinda A.
- Fulton Robert S.
- Furey Terrence S.
- Furuhashi Mie
- Förste Silke
- Gabisi Abdul M.
- Gage Diane
- Gaige Tony
- Galgoczy Petra
- Gallegos Celsa
- Galvez Michael
- Gammon Stuart
- Gao Anwu
- Gao Jimei
- Gao Quan
- Gao Yang
- Gao Yimei
- Garcia Carmen
- Garcia Emilio
- Garcia Marvin
- Garcia Ricardo M, III
- Garcia-Martinez Antonio
- Gardner Alison
- Gardner Alison
- Garduno Consuelo
- Gardyna Steph
- Garner Patrick
- Garner Toni T.
- Garnes Jeffrey A.
- Garnett Jane
- Garza Melissa
- Gatewood Joseph M.
- Gatland Leigh
- Gatland Lindsay
- Gattung Stacie
- Gay Laura
- Gearin Gary
- Gebreyesus Binyam
- Gelein Cynthia
- Gelpke Maartin
- Gench Stephanie L.
- Geng Jianing
- Georgescu Anca
- Geotina Amy
- Ghori Jilur
- Ghose Sayantan
- Gibbs Ben
- Gibbs Richard A.
- Gibson Diane
- Gibson Elizabeth
- Gifford Mary
- Gil Isaias
- Gilbert James
- Gilby Lisa
- Gill Rachel
- Gillet Will
- Gillson Christopher
- Gilna Paul
- Gimmel Verena
- Gingrich Jeff
- Giovanelli Kira
- Glavina Tijana
- Glithero Rebecca
- Glöckner Gernot
- Gnerre Sante
- Gnirke Andreas
- Gold Darren
- Golinveaux Kristen
- Gomez Maria
- Gong Guanghui
- Gong Jinying
- Gonzales Eidelyn
- Gonzalez Guillermo B.
- Gooderham April
- Goodstadt Leo
- Goodstein David
- Goodwin Lynne A.
- Gordon Catherine
- Gordon Laurie A.
- Gordon Seth
- Gorton Matthew
- Gorvad Ann
- Gould Christine
- Goyea Ernest
- Goyette Audra
- Grady Deborah I.
- Grady Michelle L.
- Grafham Darren
- Graham Joe
- Grandbois Edward
- Grant Jennifer
- Grant Michael
- Grant Susan
- Graves Tina A.
- Gray Bruce
- Gray Emma
- Gray Lain
- Green Lisa
- Greenhalgh James
- Greenhill Joe
- Gregg Philippa
- Gregory Simon
- Grewal Nennu
- Gribble Susan
- Griffith Jeffrey K.
- Griffiths Coline
- Griffiths Ed
- Griffiths Mark
- Griffiths-Jones Sam
- Grigoriev Igor
- Grimwood Jane
- Grocock Russell
- Groza Matthew
- Gu Jingli
- Gu Jun
- Gu Jun
- Gu Wenyi
- Gu Wenyi
- Gu Xiaochang
- Guan Qiaoning
- Guarin Hannibal
- Guel Metzalli
- Guerra William
- Guevara Whitney V.
- Gui Qi
- Gunaratne Preethi
- Gunning Kate
- Guo Daorong
- Guo Jane
- Guo Lili
- Gustafson Erik
- Guthrie Ian
- Guyer Mark
- Gwilliam Rhian
- Gyaltsen Kunsang
- Gyapay Gábor
- Görlich Yvonne
- Ha Chi
- Hafez Nabil
- Haglund Krista
- Hagopian Daniel
- Hagos Birhane
- Haim Allen
- Hajek Patrick
- Hall Brett Lynn
- Hall Brittany
- Hall Jennifer
- Hall Rebekah
- Hall-Tamly Gretta
- Halls Karen
- Hallsworth-Pepin Kym
- Hamada Junko
- Hamilton Cerissa
- Hamilton Keelan A.
- Hamilton Matt
- Hamlett John
- Hamlett John
- Hammon Nancy
- Hammond Martin
- Hammond Sha
- Hammond Sian
- Hamza Khalid
- Han Guiqing
- Han Shunsheng
- Han Xurong
- Hanak Vincent A.
- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
- Harley Joanne
- Harper David
- Harper Georgina
- Harper Patrik
- Harradence Grant
- Harris Anthony
- Harrison Charlene-Lou
- Harrison Elliot
- Harrison Ruth
- Hart Elizabeth
- Hasegawa Tomoko
- Hashimoto Etsuko
- Hashimoto Wakako
- Hassan Daniel
- Hatcher Beath
- Hattori Masahira
- Haugen Eric
- Haussler David
- Havlak Paul
- Hawes Alicia C.
- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
- Hawkins Trevor
- Hawley Kellie
- Haydu Lauren
- Hayes Kerry
- He Fengying
- He Jiaying
- He Lin
- Heaford Andrew
- Heath Paul
- Heathcott Rosemary
- Heilig Roland
- Heiner Cheryl
- Heinze Ivonne
- Heitmann Katja
- Helfenbein Keven
- Heller Andrew
- Hellsten Uffe
- Hembry Cathy
- Henderson Carl
- Henderson Nicholas
- Henderson Nina
- Hendrix David
- Hennig Steffen
- Henning Karla
- Hepa Victor
- Herd Tim
- Herman Charles
- Hernandez Judith
- Hernandez Omar
- Herseim Allyson
- Hewitt Stephen
- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
- Hillier LaDeana
- Hillyard Guy
- Hines Sandra
- Hinkins Russell
- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
- Hogues Marilyn E.
- Holden Jane
- Holdgate Janet
- Hollaway Mara
- Hollins Barbara
- Holloway Ele
- Holmes Andrea
- Holmes Ian
- Holmes Sarah
- Holroyd Simon
- Holtz Ann
- Holtzer Caleb
- Homsi Deana K.
- Homsi Farah J.
- Honan Tracy
- Hood Leroy
- Hooper Alison
- Hopewell Lucy
- Hopkins Ben
- Horne Jennifer
- Hornett Gary
- Hornischer Klaus
- Hornsby Amber
- Hornsby Geoff
- Hornsby Tony
- Horsley Sharon
- Horton Roger
- Hosage-Norman Catherine
- Hosoda Kei
- Hosono Katsuhiro
- Hosseini Roya
- Hou Shunfang
- Hou Xiaodi
- Houde Nathan
- Howard Philip
- Howard Stephanie R.
- Howden Philip
- Howe Kevin
- Howell Gareth
- Howell Latoya Lynette
- Howells Sally Lucinda
- Hsu Fan
- Hu George
- Hu Jie
- Hu Songnian
- Huang Fang
- Huang Guyang
- Huang Katherine
- Huang Mei
- Huang Wayne
- Huang Wei
- Huang Wei
- Huang Wei
- Huang Zhengping
- Hubbard Timothy
- Huber James W.
- Huckle Elizabeth
- Hue Heather
- Hughes Jaime
- Hughes Jennifer
- Hughes Lee
- Hughes-Hull Hillary
- Hull Louisa
- Hulme Bill
- Hulyk Steven
- Hume Jennifer
- Hummeric Holger
- Humphray Sean
- Humphries David
- Humphries Matthew
- Hunt Adrienne
- Hunt Michael
- Hunt Paul
- Hunt Sarah
- Hunter Giselle
- Hunter Rov, II
- Hupman Matt
- Huynh Sandy
- Hyde David
- Hynds Christopher
- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
- Inagaki Naomi
- Ince Michael
- Ingram Drew
- Inoue Shuuji
- Isak Amber
- Isherwood Judith
- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
- Isozaki Emi
- Israni Sanjay
- Ito Fumiaki
- Ito Noriko
- Itoh Takehiko
- Iwakawa Shinobu
- Iwatate Mariko
- Iwatsu Mikiko
- Iyer Vivek
- Izatt Janet
- Izmajlowicz Monica
- Izumiyama Tomohiro
- Jacintho Mark
- Jackson Laronda R.
- Jackson Terri
- Jacob Leni Susan
- Jaeger Sara
- Jaffe David B.
- Jahn Niels
- Jaklevic Joseph
- Jaklevic Michael
- James Kent W.
- Jareborg Niclas
- Jarek Michael
- Jassal Bijay
- Jeffery Grant
- Jeffery Kim
- Jeffrey Colin
- Jekosch Kerstin
- Jenkins Lee
- Jett Jamie
- Jewett Phillip E.
- Jia Jia
- Jia Jia
- Jia Nan
- Jia Xingchang
- Jiang Lu
- Jiang Yanrui
- Jiang Ziyou
- Jimenez Alberto
- Jin Jian
- Jin Yetao
- Jin Yongsan
- Johansen Tina
- Johnson Bennie
- Johnson Cheryl
- Johnson Christopher
- Johnson David
- Johnson Douglas
- Johnson Genevieve
- Johnson Lori
- Johnson Mark
- Johnson Philip
- Johnson Rudy
- Johnson Stephanie
- Jolivet Angela
- Jolley Keith
- Jones Abigail
- Jones Charlien
- Jones Claire
- Jones Juliet
- Jones Matthew
- Jones Michael
- Jones Micheil
- Jones Myrna D.
- Jones Steven
- Jong Pieter De
- Jordan Yun
- Joseph Shirin
- Joy Ann
- Joy Linsey
- Joy Victoria
- Joyce Gillian
- Jubb Mark
- Jung Eugine
- Järke Doris
- Kadner Kristen
- Kagan Ryan
- Kahsai Orsalem
- Kaida Kaoru
- Kale Pat
- Kalicki-Veizer Joelle
- Kamal Michael
- Kamat Asha
- Kamholz Sandra
- Kana Arnold
- Kang Hui
- Kang Kelie
- Kang Ning
- Kapur Hitesh
- Karolchik Donna
- Karunaratne Kanchi
- Kasprzyk Arek
- Katayama Takujiro
- Kato Takako
- Kauer Gerhard
- Kaul Rajinder
- Kaur Amardeep
- Kawagoe Chiharu
- Kawasaki Kazuhiko
- Kay Michael
- Kaye Danielle
- Kearney Lyndal
- Keefe Damian
- Keen Gifford
- Keenan Stephen
- Kegelmeyer Laura
- Kegg Lisa
- Kelley Simon
- Kells Cristyn
- Kelly Shayna P.
- Kelly Susan H.
- Kershaw Joanna
- Kettleborough Ross
- Keys David
- Khan Arsi
- Khan Umer F.
- Khan Ziad Mohid
- Khine Susu
- Khurama Divya
- Kidd Cathy
- Kierstan Peter
- Kieu Alix
- Kim Jennifer
- Kim Joomyeong
- Kim Kyung
- Kimball Heather
- Kimberley Andrew
- Kimura Moe
- King Andrew
- King Laquisha Monique
- King Mary-Clare
- Kingsley Simon
- Kingswood Colin
- Kisamo Haika
- Kisner Peter
- Kitts Paul
- Kiyooka Miho
- Klages Sven
- Klingle Gillian
- Knights Andrew
- Kobayashi Mai
- Kodira Chinnappa
- Kohlberg Sara
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- Kolbe William
- Kong Yi
- Korf Ian
- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
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- Kremmidiotis Gabriel
- Krogh Anders
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- Kruchowski Scott S.
- Kube Michael
- Kubischta Duane
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- Lambart Christine
- Lamble Ralph
- Lamerdin Jane E.
- Lander Eric S.
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- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
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- Lucier Raymond L.
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- Madabhushi Ramki
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- Sun Yu
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- Sutherland Robert D.
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- Tatum Owatha I.
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- Tian Chaoguang
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- Tin-Wollam Aye M.
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- Togashi Naoko
- Tomizawa Iori
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- Tong Jingli
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- Ukegbu Ogechi Nkemdirim
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- Un Chun
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- Upson Darren
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- Viknaraja Ramya
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- Vine Wendy
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- Vo Andy
- Vo Nu
- Voak Paul
- Vollenhoven David
- Wada Hiromi
- Wagner Mark
- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
- Wallace John
- Wallis Justine
- Wallis Michelle
- Walsh Jennifer
- Walsham Natalie
- Wan Ma
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- Wang Ying
- Wang Yuanyuan
- Wangchuck Tsering
- Wangdi Tsering
- Ward-Moore Stephanie
- Warren Graham
- Warren James T.
- Warry Georgina
- Watanabe Hidemi
- Watanabe Saki
- Waterston Robert H.
- Watson Andy
- Watt Nicola
- Webb Anthony
- Webb Jeannette
- Webber Caleb
- Weber Ryan J.
- Wehri Edward
- Wei Shulin
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- Weidenbach Richard
- Weinstock George
- Weinstock Keith
- Weir John
- Weissenbach Jean
- Wells Alan
- Wells Sarah
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- Wen Gaiping
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- Wesley Mary Melissa
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- West Tony
- Wetterstrand Kris
- Wheatley Angela
- Wheatley Carl
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- Wheeler Gideon
- Wheeler Jeremy
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- White Adam
- White Amelia
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- Wickremasinghe Manosha I.
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- Wilkinson Jane
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- Williams Albert L.
- Williams Andy
- Williams Bill
- Williams Gabrielle A.
- Williams Leanne
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- Williamson Helen
- Wills Patricia L.
- Wills Richard
- Wilmer Tamsin
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- Worley Kim Carlyle
- Woyke Tanja
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- Wray Paul
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- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
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- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
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- Wu Xiaojing
- Wu Zaining
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- Wycoff-Montenegro Melissa
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- Xi Yan
- Xi Yingying
- Xie Fei
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- Xu Alex
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- Xu Jing
- Xu Ruqin
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- Xu Wei
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- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
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- Yang Shudong
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- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
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- Yeshitela Rahel Retta
- Yoakum Martin
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- Yue Shujie
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- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
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- Zhan Guoping
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- Zhang Haiqing
- Zhang Haiqing
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- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
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- Zhang Jiuchun
- Zhang Jiuchun
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- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
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- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.
- Author
- Ahmed Munaza
- Aitken Stuart
- Aitman Timothy
- Akawi Nadia
- Al Turki Saeed
- Alachkar Hana
- Ali Sonia
- Allen Hana Lango
- Allen Louise
- Allsup David
- Alvi Mohsan
- Ambegaonkar Gautum
- Ambridge Kirsty
- Anderson Carl
- Anderson Julie
- Anjum Uruj
- Anney Richard
- Antony Dinu
- Antrobus Richard
- Archer Hayley
- Armstrong Ruth
- Armstrong Ruth
- Arno Gavin
- Artigas Maria Soler
- Arumugakani Gururaj
- Ashford Sofie
- Astle William
- Attwood Antony
- Austin Steve
- Awada Jana
- Ayub Muhammad
- Bacchelli Chiara
- Bakchoul Tamam
- Balasubramaniam Senduran
- Balasubramanian Meena
- Banka Siddharth
- Baralle Diana
- Bariana Tadbir K.
- Barnicoat Angela
- Barrett Daniel M.
- Barrett Jeffrey C.
- Barrett Jeffrey C.
- Barroso Inês
- Batstone Paul
- Baty David
- Baxendale Helen
- Bayzetinova Tanya
- Beales Phil
- Bennett Chris
- Bennett David
- Bentham Jamie
- Berg Jonathan
- Bernhard Birgitta
- Bethune Claire
- Bevan A. Paul
- Bhattacharya Shoumo
- Bibi Shahnaz
- Birney Ewan
- Bitner-Glindzicz Maria
- Bitner-Glindzicz Maria
- Blackwood Douglas
- Blair Edward
- Bleda Marta
- Blyth Moira
- Bobrow Martin
- Bochukova Elena
- Boggard Harm
- Bohanna David
- Bolton Patrick
- Bolton-Maggs Paula
- Booth Claire
- Bounds Rebecca
- Bourdon Louise
- Bourn David
- Boustred Chris
- Bradley John R.
- Bradley Lisa
- Brady Angela
- Brady Angie
- Breen Gerome
- Brent Simon
- Brewer Carole
- Brown Matthew
- Browning Michael
- Brunstrom Kate
- Bryant Emily
- Bryson Christine
- Bunyan David J.
- Burn John
- Burns Siobhan
- Calissano Mattia
- Calleja Paul
- Canham Natalie
- Canham Natalie
- Carmichael Jenny
- Carss Keren
- Carss Keren
- Carss Keren J.
- Carvill Gemma L.
- Castle Bruce
- Caulfield Mark
- Chalmers Elizabeth
- Chandler Kate
- Chandra Anita
- Chatterjee Krishna
- Chatzimichali Elena
- Chen Lu
- Chinnery Patrick
- Chitre Manali
- Church Colin
- Ciampi Antonio
- Cilliers Deirdre
- Cirak Sebhattin
- Clapham Peter
- Clarke Angus
- Clasper Susan
- Clayton Stephen
- Clayton-Smith Jill
- Clayton-Smith Jill
- Clement Emma
- Clement Gail
- Clements-Brod Naomi
- Clowes Virginia
- Clowes Virginia
- Coates Andrea
- Coates Guy
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- Cole Trevor
- Colgiu Irina
- Collier David
- Collins Amanda
- Collins Peter
- Collinson Morag N.
- Connell Fiona
- Cooper Nichola
- Cooper Nicola
- Cosgrove Catherine
- Cox Helen
- Cox Tony
- Craddock Nick
- Creaser-Myers Amanda
- Cresswell Lara
- Crooks Lucy
- Cross Gareth
- Cross J. Helen
- Crow Yanick
- Curran Sarah
- Curtis David
- D?Alessandro Mariella
- Dabir Tabib
- DaCosta Rosa
- Daly Allan
- Daugherty Louise
- Davidson Rosemarie
- Davies Sally
- Davies Sophie
- Davis John
- Day Ian N.M.
- Day-Williams Aaron
- de Vries Dylan
- De Vries Minka
- Dean John
- Debelle Geoff D.
- Deegan Patrick
- Deevi Sri V.V.
- Deshpande Charu
- Deshpande Charu
- Devlin Gemma
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- Down Thomas
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- Du Yuanping
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- Dunham Ian
- Eason Jacqueline
- Edgar David
- Edkins Sarah
- Egner William
- Ellard Sian
- Ellis Ian
- Ellis Peter
- Elmslie Frances
- Erber Wendy N.
- Erwood Marie
- Evans David
- Evans Karenza
- Everest Sarah
- Everington Tamara
- Faroogi Sadaf
- Fatemifar Ghazaleh
- Favier Remi
- Fendick Tina
- Firth Helen
- Firth Helen V.
- Fisher Richard
- Fitzgerald Tomas W.
- FitzPatrick David R.
- Fitzpatrick David R.
- Fletcher Debra
- Flicek Paul
- Flinter Frances
- Flinter Frances
- Flyod James
- Foley A. Reghan
- Foulds Nicola
- Fox James C.
- Franklin Christopher S.
- Frary Amy
- Freson Kathleen
- Fry Andrew
- Fryer Alan
- Furie Bruce
- Furnell Abigail
- Futema Marta
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- Geihs Matthias
- Geschwind Daniel
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- Ghali Neeti
- Ghataorhe Pavandeep K.
- Ghurye Rohit
- Gibbons Richard
- Gibbs Simon
- Gill Harinder
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- Gomez Keith
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- Gorman Kathleen M.
- Goudie David
- Gray Emma
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- Greene Daniel
- Greene Philip
- Greenhalgh Alan
- Greenhalgh Lynn
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- Griffin Heather
- Grigoriadou Sofia
- Grozeva Detelina
- Gräf Stefan
- Guo Xiaosen
- Guo Xueqin
- Gurling Hugh
- Haack Tobias B.
- Hackett Scott
- Hadinnapola Charaka
- Hague Rosie
- Haimel Matthias
- Halmagyi Csaba
- Hammerton Tracey
- Harrison Lucy
- Harrison Rachel
- Harrison Victoria
- Hart Daniel
- Hart Deborah
- Hawkins Rose
- Hayman Grant
- He Liu
- Heemskerk Johan W.M.
- Hellens Stephen
- Henderson Alex
- Henderson Robert
- Hendricks Audrey
- Hensiek Anke
- Henskens Yvonne
- Herwadkar Archana
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- Hildyard Lucy
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- Holder Muriel
- Holder Susan
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- Hollingsworth Georgina
- Holmans Peter
- Homfray Tessa
- Howie Bryan
- Hu Fengyuan
- Huang Liren
- Hubbard Tim
- Huissoon Aarnoud
- Humbert Marc
- Humphreys Mervyn
- Humphries Steve E.
- Hurles Matthew E.
- Hurles Matthew E.
- Hurst Jane
- Hurst Jane
- Hutton Ben
- Hysi Pirro
- Ingram Stuart
- Iotchkova Valentina
- Irving Melita
- Islam Lily
- Jackson Andrew
- Jackson David K.
- James Roger
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- Kingston Nathalie
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- Kivuva Emma
- Kolb-Kokocinski Anja
- Koziell Ania
- Kraus Alison
- Krishnakumar Deepa
- Krishnappa Netravathi
- Kuijpers Taco W.
- Kumar Dhavendra
- Kumar V. K. Ajith
- Kumararatne Dinakantha
- Kurian Manju
- Kurian Manju A.
- Lachance Genevieve
- Lachlan Katherine
- Laffan Michael A.
- Lam Wayne
- Lambert Michele P.
- Lampe Anne
- Langford Cordelia
- Langman Caroline
- Lawrie Allan
- Lawson Daniel
- Lear Sara
- Lee Irene
- Lees Melissa
- Lees Melissa
- Lek Monkol
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- Li Rui
- Li Yingrui
- Liang Jieqin
- Liesner Ri
- Lim Derek
- Lin Hong
- Linger Rachel
- Liu Ryan
- Longhurst Hilary
- Longman Cheryl
- Lopes Margarida
- Lorenzo Lorena
- Lowther Gordon
- Lynch Sally A.
- Lönnqvist Jouko
- MacArthur Daniel
- Machado Rajiv
- Mackenzie Rob
- MacLaren Robert
- Magee Alex
- Maher Eamonn
- Maher Eamonn R.
- Maher Eddy
- Maimaris Jesmeen
- Male Alison
- Mangles Sarah
- Manson Ania
- Mansour Sahar
- Mapeta Rutendo
- Marchini Jonathan
- Marenne Gaëlle
- Marks Karen
- Markus Hugh S.
- Martin Jennifer
- Martin Katherine
- Masati Larahmie
- Maslen John
- Mason Laura E.
- Massimo Mangino
- Mathias Mary
- Mathieson Iain
- Matser Vera
- Maw Anna
- Maye Una
- McCann Emma
- McConnell Vivienne
- McCullagh Gary
- McDermott Elizabeth
- McEntagart Meriel
- McGowan Ruth
- McGuffin Peter
- McIntosh Andrew
- McJannet Coleen
- McKay Kirsten
- McKechanie Andrew G.
- McKee Shane
- McMullan Dominic J.
- McNerlan Susan
- McQuillin Andrew
- McRae Jeremy F.
- McTague Amy
- McWilliam Catherine
- Meacham Stuart
- Meehan Sharon
- Mefford Heather C.
- Megy Karyn
- Mehta Sarju
- Mehta Sarju
- Metcalfe Kay
- Metrustry Sarah
- Meyer Esther
- Michaelides Michel
- Middleton Anna
- Miedzybrodzka Zosia
- Miles Emma
- Millar Carolyn M.
- Millichap John J.
- Mitchison Hannah
- Moayyeri Alireza
- Mohammed Shehla
- Moledina Shahin
- Montgomery Tara
- Moore Anthony
- Moore David
- Morgan Sian
- Morrell Nicholas
- Morris James
- Morton Jenny
- Morton Jenny
- Mugalaasi Hood
- Mumford Andrew
- Muntoni Francesco
- Murday Victoria
- Murng Sai
- Murphy Elaine
- Murphy Helen
- Naik Swati
- Nejentsev Sergey
- Nellåker Chris
- Nemeth Andrea
- Nevitt Louise
- Newbury-Ecob Ruth
- Noorani Sadia
- Norman Andrew
- Northstone Kate
- Nurden Paquita
- O'Donovan Michael
- O'Rahilly Stephen
- O'Shea Rosie
- Ogilvie Caroline
- Oksenhendler Eric
- Ong Kai-Ren
- Onoufriadis Alexandros
- Oualkacha Karim
- Ouwehand Willem H.
- Owen Michael J.
- Paciorkowski Alex R.
- Palotie Aarno
- Panoutsopoulou Kalliope
- Papadia Sofia
- Park Soo-Mi
- Park Soo-Mi
- Parker Alasdair
- Parker Michael
- Parker Michael J.
- Parker Victoria
- Parr Jeremy R.
- Pasi John
- Patch Chris
- Patel Chirag
- Paternoster Lavinia
- Paterson Joan
- Paterson Joan
- Paunio Tiina
- Payne Felicity
- Payne Jeanette
- Payne Stewart
- Peacock Andrew
- Peerlinck Kathelijne
- Penkett Christopher J.
- Pepke-Zaba Joanna
- Perrett Daniel
- Perry David J.
- Phipps Julie
- Pietilainen Olli
- Pilz Daniela T.
- Plagnol Vincent
- Poduri Annapurna
- Pollard Martin
- Pollock Val
- Polwarth Gary
- Ponsford Mark
- Pottinger Caroline
- Poulton Joanna
- Pratt Norman
- Prescott Katrina
- Pressler Ronit M.
- Price Sue
- Pridham Abigail
- Prigmore Elena
- Procter Annie
- Purnell Hellen
- Qasim Waseem
- Quail Michael A.
- Quarrell Oliver
- Quaye Lydia
- Quinti Isabella
- Ragge Nicola
- Rahbari Raheleh
- Rajan Diana
- Randall Josh
- Rankin Julia
- Rankin Julia
- Rankin Stuart
- Raymond F. Lucy
- Raymond F. Lucy
- Raymond Lucy
- Raymond Lucy
- Rehnstrom Karola
- Rehnström Karola
- Reich Adi
- Reid Evan
- Rhodes Christopher J.
- Rice Debbie
- Richards Michael
- Richardson Sylvia
- Richter Alex
- Ring Susan
- Ritchie Graham R.S.
- Robert Leema
- Roberts Eileen
- Roberts Gillian
- Roberts Irene
- Roberts Jonathan
- Roberts Nicola
- Roberts Paul
- Rondina Matthew
- Ross Alison
- Rosser Elisabeth
- Rosser Elisabeth
- Roughley Catherine
- Rue-Albrecht Kevin
- Saggar Anand
- Samant Shalaka
- Samarghitean Crina
- Sampson Julian
- Sanchis-Juan Alba
- Sanchis-Juan Alba
- Sandford Richard
- Sandford Richard
- Santra Saikat
- Sargur Ravishankar
- Sarkar Ajoy
- Savage David B.
- Savic Sinisa
- Scambler Peter
- Scheffer Ingrid E.
- Schiffels Stephen
- Schmidts Miriam
- Schneider Amy L.
- Schoenmakers Nadia
- Schulman Sol
- Schulze Harald
- Schweiger Susann
- Scott Richard
- Scott Richard
- Scully Marie
- Scurr Ingrid
- Selby Ann
- Seller Anneke
- Semple Robert K.
- Seneviratne Suranjith
- Sequeira Cheryl
- Serra Eva
- Sewell Carrock
- Shamardina Olga
- Shannon Nora
- Sharif Saba
- Sharp Sally I.
- Shaw-Smith Charles
- Shearing Emma
- Shears Debbie
- Sheridan Eamonn
- Shin So-Youn
- Shipley Debbie
- Sieciechowicz Diana
- Sifrim Alejandro
- Simeoni Ilenia
- Simonic Ingrid
- Simpson Michael A.
- Singh Tarjinder
- Singzon Roldan
- Sivapalaratnam Suthesh
- Skitt Zara
- Skuse David
- Small Kerrin
- Smith Audrey
- Smith Kath
- Smith Kenneth
- Smithson Sarah
- Sneddon Linda
- Sohal Aman
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- Southgate Laura
- Spasic-Boskovic Olivera
- Spinelli Egidio
- Splitt Miranda
- Squires Miranda
- St Clair David
- St Pourcian Beate
- Staines Simon
- Stalker Jim
- Staples Emily
- Stauss Hans
- Stein Penelope
- Stephens Jonathan
- Stevens Elizabeth
- Stewart Fiona
- Stewart Helen
- Stirrups Kathleen
- Stock Sophie
- Straub Volker
- Sun Jianping
- Suntharalingam Jay
- Suri Mohnish
- Sutton Vivienne
- Suvisaari Jaana
- Swaminathan Ganesh Jawahar
- Sweeney Elizabeth
- Tachmazidou Ionna
- Tait R. Campbell
- Talks Kate
- Tan Yvonne
- Tatton-Brown Kate
- Taylor Cat
- Taylor Rohan
- Tein Mark
- Temple I. Karen
- Thachil Jecko
- Thaventhiran James
- Thomas Ellen
- Thomas Moira
- Thompson Dorothy
- Thomson Jenny
- Thrasher Adrian
- Tischkowitz Marc
- Tischkowitz Marc
- Titterton Catherine
- Tivey Adrian R.
- Tobin Martin D.
- Toh Cheng-Hock
- Tomkins Susan
- Torokwa Audrey
- Toshner Mark
- Treacy Becky
- Treacy Carmen
- Trembath Richard
- Tuna Salih
- Turek Wojciech
- Turner Claire
- Turnpenny Peter
- Turro Ernest
- Tysoe Carolyn
- Valdes Ana
- Van Geet Chris
- Van Kogelenberg Margriet
- Vandersteen Anthony
- Varghese Vinod
- Vasudevan Pradeep
- Veltman Marijke
- Vijayarangakannan Parthiban
- Vijayarangakannan Parthiban
- Visscher Peter M.
- Vogt Julie
- Vogt Julie
- von Ziegenweldt Julie
- Vonk Noordegraaf Anton
- Wain Louise V.
- Wakeling Emma
- Wakeling Emma
- Wallwark Sarah
- Walters James T.R.
- Wang Guangbiao
- Wang Jun
- Wang Yu
- Wanjiku Ivy
- Ward Kirsten
- Warner Timothy Q.
- Wassmer Evangeline
- Wassmer Evangeline
- Waters Jonathon
- Watkins Hugh
- Weber Astrid
- Webster Andrew
- Welch Steve
- Wellesley Diana
- Westbury Sarah
- Wharton John
- Wheeler Elanor
- Whiteford Margo
- Whitehorn Deborah
- Whyte Tamieka
- Widaa Sara
- Wilcox Sarah
- Wilkins Martin
- Wilkinson Emily
- Willcocks Lisa
- Williams Denise
- Williams Hywel
- Williams Nicola
- Williamson Catherine
- Williamson Kathleen A.
- Wilson Crispian
- Wilson Louise
- Wong Kim
- Woods Geoff
- Woods Geoffrey
- Wort John
- Wragg Christopher
- Wright Caroline F.
- Wright Michael
- Xu ChangJiang
- Yang Jian
- Yates Laura
- Yau Michael
- Yeatman Nigel
- Yong Patrick
- Young Tim
- Yu Ping
- Zhang Fend
- Zhang Pingbo
- Publication venue
- AJHG
- Publication date
- 01/01/2019
- Field of study
The occurrence of non-epileptic hyperkinetic movements in the context of developmental epileptic encephalopathies is an increasingly recognized phenomenon. Identification of causative mutations provides an important insight into common pathogenic mechanisms that cause both seizures and abnormal motor control. We report bi-allelic loss-of-function CACNA1B variants in six children from three unrelated families whose affected members present with a complex and progressive neurological syndrome. All affected individuals presented with epileptic encephalopathy, severe neurodevelopmental delay (often with regression), and a hyperkinetic movement disorder. Additional neurological features included postnatal microcephaly and hypotonia. Five children died in childhood or adolescence (mean age of death: 9 years), mainly as a result of secondary respiratory complications. CACNA1B encodes the pore-forming subunit of the pre-synaptic neuronal voltage-gated calcium channel Cav2.2/N-type, crucial for SNARE-mediated neurotransmission, particularly in the early postnatal period. Bi-allelic loss-of-function variants in CACNA1B are predicted to cause disruption of Ca2+ influx, leading to impaired synaptic neurotransmission. The resultant effect on neuronal function is likely to be important in the development of involuntary movements and epilepsy. Overall, our findings provide further evidence for the key role of Cav2.2 in normal human neurodevelopment.MAK is funded by an NIHR Research Professorship and receives funding from the Wellcome Trust, Great Ormond Street Children's Hospital Charity, and Rosetrees Trust. E.M. received funding from the Rosetrees Trust (CD-A53) and Great Ormond Street Hospital Children's Charity. K.G. received funding from Temple Street Foundation. A.M. is funded by Great Ormond Street Hospital, the National Institute for Health Research (NIHR), and Biomedical Research Centre. F.L.R. and D.G. are funded by Cambridge Biomedical Research Centre. K.C. and A.S.J. are funded by NIHR Bioresource for Rare Diseases. The DDD Study presents independent research commissioned by the Health Innovation Challenge Fund (grant number HICF-1009-003), a parallel funding partnership between the Wellcome Trust and the Department of Health, and the Wellcome Trust Sanger Institute (grant number WT098051). We acknowledge support from the UK Department of Health via the NIHR comprehensive Biomedical Research Centre award to Guy's and St. Thomas' National Health Service (NHS) Foundation Trust in partnership with King's College London. This research was also supported by the NIHR Great Ormond Street Hospital Biomedical Research Centre. J.H.C. is in receipt of an NIHR Senior Investigator Award. The research team acknowledges the support of the NIHR through the Comprehensive Clinical Research Network. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, Department of Health, or Wellcome Trust. E.R.M. acknowledges support from NIHR Cambridge Biomedical Research Centre, an NIHR Senior Investigator Award, and the University of Cambridge has received salary support in respect of E.R.M. from the NHS in the East of England through the Clinical Academic Reserve. I.E.S. is supported by the National Health and Medical Research Council of Australia (Program Grant and Practitioner Fellowship)
Advocates and adversaries: examining the role of supplier advocacy on customer reacquisition
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
The CRAPome: A contaminant repository for affinity purification-mass spectrometry data
- Author
- A Breitkreutz
- A Kasprzyk
- A Keller
- A Pichlmair
- Abdallah al-Hakim
- AC Gingras
- AC Gingras
- AC Gingras
- AI Nesvizhskii
- AI Nesvizhskii
- AI Nesvizhskii
- AJ Tackett
- AK Al-Hakim
- Albert J R Heck
- Alexey I Nesvizhskii
- Amber L Couzens
- Anne-Claude Gingras
- Annie Bouchard
- Beatriz Gonzalez Badillo
- Benoit Coulombe
- Brian Raught
- C Jeronimo
- D Fermin
- D Forget
- Damian Fermin
- Daniel Durocher
- Dattatreya Mellacheruvu
- Denis Faubert
- DL Daniels
- DV Skarra
- DW Huang
- EL Rudashevskaya
- EW Deutsch
- F Kruiswijk
- G Tzivion
- GI Chen
- GI Chen
- Giulio Superti-Furga
- H Choi
- H Choi
- H Miki
- Hyungwon Choi
- Ileana M Cristea
- IM Cristea
- Jacques Colinge
- Jean-Philippe Lambert
- KD Pruitt
- Keiryn L Bennett
- L Trinkle-Mulcahy
- L Trinkle-Mulcahy
- M Goudreault
- M Selbach
- M Varjosalo
- M Wartmann
- Marilyn Goudreault
- Matthias Gstaiger
- ME Sardiu
- Mihaela E Sardiu
- Mike P Washburn
- MJ de Hoon
- MJ Kean
- NC Hubner
- Nicole A St-Denis
- Nina C Hubner
- R Craig
- RD Page
- Richard D Bagshaw
- RM Ewing
- Rob M Ewing
- Ruedi Aebersold
- S Razick
- S Sato
- Shabaz Mohammed
- Simon Hauri
- SS Thakur
- Teck Yew Low
- TM Greco
- Tony Pawson
- Tuo Li
- Vincentius A Halim
- W de Lau
- Wade H Dunham
- WH Dunham
- WH Dunham
- Yana V Miteva
- YC Tsai
- Z Shen
- Zachary Wright
- Zhen-Yuan Lin
- Publication venue
- Publication date
- 01/01/2013
- Field of study
10.1038/nmeth.2557Nature Methods108730-73
Profiling Surgeon Performance for Breast Cancer Lumpectomy by Composite Measurement of Reoperations, Cosmetic Outcomes, and Patient Preferences
- Author
- AJ Isaacs
- AK Jha
- AK Jha
- AM Schulman
- Annie L. Dunham
- Choua A. Vang
- DL Eck
- DM Atisha
- ER St John
- ES Spatz
- F MacNeill
- GF Beadle
- HS Cody 3rd
- J Dimick
- J Landercasper
- J Landercasper
- J Landercasper
- J Landercasper
- J Landercasper
- J Linebarger
- J Mook
- Jared H. Linebarger
- JB Dimick
- JC Boughey
- Jeffrey Landercasper
- JH Volders
- JR Harris
- K Ojala
- KY Bilimoria
- L Cruz De La
- LE McCahill
- LG Wilke
- Luis D. Ramirez
- M Morrow
- M Morrow
- M Porter
- MB El-Tamer
- ME Porter
- MJ Barry
- MJ Cardoso
- MR Decker
- MR Turco Del
- OM Fayanju
- R Jeevan
- R Rajaram
- S Mullangi
- SA Carter
- SE Abe
- T Schwartz
- TJ Smith
- TO Adegboyega
- VJ Dzau
- WL Ong
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
High-mass Starless Clumps in the Inner Galactic Plane: The Sample and Dust Properties
- Author
- Aguirre J. E.
- Annie Zavagno
- Barnes P. J.
- Benjamin R. A.
- Bressert E.
- Butler M. J.
- Carey S. J.
- Christian Henkel
- Churchwell E.
- Cyganowski C. J.
- Dempsey J. T.
- Dunham M. K.
- Elia D.
- Feng S.
- Gutermuth R. A.
- Gutermuth R. A.
- Heiderman A.
- Hildebrand R. H.
- Hong-Li Liu
- Jackson J. M.
- Jin-Zeng Li
- Jinghua Yuan
- Kauffmann J.
- Kauffmann J.
- Ke Wang
- Kong S.
- Lada C. J.
- Lumsden S. L.
- McKee C. F.
- Molinari S.
- Molinari S.
- Mueller K. E.
- Neal J. Evans II
- Newville M.
- Ossenkopf V.
- Reid M. J.
- Saraceno P.
- Sato M.
- Shirley Y. L.
- Simon P. Ellingsen
- Skrutskie M. F.
- Svoboda B. E.
- Tan J. C.
- Tan J. C.
- Tan J. C.
- Tie Liu
- Wang K.
- Wang K.
- Werner M. W.
- Yuefang Wu
- Zhang Q.
- Publication venue
- 'American Astronomical Society'
- Publication date
- Field of study
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors
- Author
- Afzal Samina
- Agamez Natalia R.
- Albrecht Steffen
- Arrowsmith Cheryl H.
- Bader Gary D.
- Barsyte-Lovejoy Dalia
- Barszczyk Mark
- Bartels Ute
- Birks Diane K.
- Bognár Laszló
- Bouffet Eric
- Bourgey Mathieu
- Bourque Guillaume
- Brudno Michael
- Carret Anne-Sophie
- Catchpoole Daniel
- Chan Jennifer A.
- Chan Tiffany S.
- Chiou Shih-Hwa
- Choi Seung Ah
- de Antonellis Pasqualino
- De Carvalho Daniel D.
- Dirks Peter B.
- Druker Harriet
- Dunham Christopher P.
- Dzamba Misko
- Eisenstat David D.
- Erdreich-Epstein Anat
- Fangusaro Jason R.
- Faria Claudia C.
- Feng Shengrui
- Fleming Adam J.
- Foreman Nicholas K.
- Fouladi Maryam
- Fried Iris
- Fryer Chris
- Fults Daniel
- Gajjar Amar
- Garami Miklós
- Garzia Livia
- Gendoo Deena M.A.
- Gillespie G. Yancey
- Golbourn Brian
- Grant Ronald
- Grundy Richard G.
- Guilhamon Paul
- Hammond Robert
- Hansford Jordan R.
- Hauser Péter
- Hawkins Cynthia E.
- Ho King Ching
- Hoffman Lindsey M.
- Hongeng Suradej
- Hortobágyi Tibor (1965-) (patológus)
- Hortobágyi Tibor
- Huang Annie
- Hukin Juliette
- Hwang Eugene I.
- Jabado Nada
- Johnston Donna L.
- Judkins Alexander R.
- Khuong-Quang Dong-Anh
- Kim Seung-Ki
- Klekner Almos
- Lafay-Cousin Lucie
- Larbcharoensub Noppadol
- Letourneau Louis
- Lu Jian-Qiang
- Lu Mei
- Lulla Rishi R.
- Lupien Mathieu
- Majewski Jacek
- Malkin David
- McGlade C. Jane
- Medina Tiago
- Mehta Vivek
- Michaud Jean
- Montpetit Alexandre
- Moore Andrew S.
- Morrissy A. Sorana
- Nakamura Hideo
- Ng Ho-keung
- Nicolaides Theodore
- Norman Joseph D.
- Phillips Joanna
- Picard Daniel
- Pietsch Torsten
- Pimentel Jose
- Planello Aline C.
- Ra Young-Shin
- Ramaswamy Vijay
- Ramsay David A.
- Reddy Alyssa T.
- Remke Marc
- Riemenschneider Alexandra N.
- Roque Lucia
- Rutka James T.
- Rutkowski Stefan
- Scheinemann Katrin
- Schüller Ulrich
- Sin-Chan Patrick
- Sirachainan Nongnuch
- Somers Gino R.
- Strother Doug
- Tabori Uri
- Taylor Michael D.
- Tihan Tarik
- Toledano Helen
- Torchia Jonathon
- Van Meter Timothy E.
- Vasiljevic Alexandre
- Wang Yin
- Warmuth-Metz Monika
- Wataya Takafumi
- Wilson Beverly
- Yip Stephen
- Yu Man
- Zelcer Shayna
- Zeller Constanze
- Publication venue
- Elsevier (Cell Press)
- Publication date
- 01/12/2016
- Field of study
We recently reported that atypical teratoid rhabdoid tumors (ATRTs) comprise at least two transcriptional subtypes with different clinical outcomes; however, the mechanisms underlying therapeutic heterogeneity remained unclear. In this study, we analyzed 191 primary ATRTs and 10 ATRT cell lines to define the genomic and epigenomic landscape of ATRTs and identify subgroup-specific therapeutic targets. We found ATRTs segregated into three epigenetic subgroups with distinct genomic profiles, SMARCB1 genotypes, and chromatin landscape that correlated with differential cellular responses to a panel of signaling and epigenetic inhibitors. Significantly, we discovered that differential methylation of a PDGFRB-associated enhancer confers specific sensitivity of group 2 ATRT cells to dasatinib and nilotinib, and suggest that these are promising therapies for this highly lethal ATRT subtype
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
- Author
- Abecasis Gonçalo R.
- Abril Josep F.
- Adzhubei Ivan
- Aldred Shelley Force
- Alioto Tyler
- Ameur Adam
- Andrews Robert M.
- Andrews Robert M.
- Antonarakis Stylianos E.
- Antonarakis Stylianos E.
- Armengol Lluis
- Asimenos George
- Asthana Saurabh
- Baertsch Robert
- Barber Galt
- Barrera Leah
- Batzoglou Serafim
- Batzoglou Serafim
- Bell Ian
- Bell Ian
- Bhinge Akshay A.
- Bickel Peter
- Bickel Peter
- Bieda Mark C.
- Bird Christine P.
- Birney Ewan
- Birney Ewan
- Birney Ewan
- Birney Ewan
- Birney Ewan
- Birney Ewan
- Blakesley Robert W.
- Bouffard Gerard G.
- Boyle Patrick J.
- Brent Michael
- Broad Institute
- Brown James B.
- Brown James B.
- Brown James B.
- Bruce Alexander W.
- Cao Hua
- Carninci Piero
- Carter Nigel P.
- Carter Nigel P.
- Castelo Robert
- Chang Jean L.
- Cheng Jill
- Cheng Jill
- Cheung Evelyn
- Chiu Kuo Ping
- Chiu Kuo Ping
- Choo Chiou Yu
- Choo Siew Woh
- Chrast Jacqueline
- Church Deanna
- Clamp Michele
- Clark Taane G.
- Clark Taane G.
- Clawson Hiram
- Clelland Gayle K.
- Clelland Gayle K.
- Collins Francis S.
- Collins Francis S.
- Cooper Gregory M.
- Cooper Gregory M.
- Cooper Sara J.
- Couttet Phillippe
- Crawford Gregory E.
- Cuff James
- Davis Sean
- Davydov Eugene
- Day Nathan
- de Bakker Paul I. W.
- de Jong Pieter J.
- Dekker Job
- Denoeud France
- Denoeud France
- Dermitzakis Emmanouil T.
- Dermitzakis Emmanouil T.
- Dermitzakis Emmanouil T.
- Dewey Colin N.
- Dhami Pawandeep
- Dhami Pawandeep
- Dickson Mark C.
- Dike Sujit
- Dillon Shane C.
- Dillon Shane C.
- Dimas Antigone
- Dorschner Michael O.
- Dovey Oliver M.
- Drenkow Jorg
- Dunham Ian
- Dunham Ian
- Dutta Anindya
- Dutta Anindya
- Ellis Peter D.
- Emanuelsson Olof
- Enroth Stefan
- Estivill Xavier
- Euskirchen Ghia
- Eyras Eduardo
- Farnham Peggy J.
- Feingold Elise A.
- Fiegler Heike
- Flamm Christoph
- Flicek Paul
- Flicek Paul
- Flicek Paul
- Flicek Paul
- Foissac Sylvain
- Fowler Joanna C.
- Frankish Adam
- Fried Claudia
- Frum Tristan T.
- Fu Yutao
- Fu Yutao
- Fulton Robert
- Ganesh Madhavan
- Genome Sequencing Center* Washington University
- Gerstein Mark
- Gerstein Mark
- Gerstein Mark
- Gerstein Mark
- Ghosh Srinka
- Ghosh Srinka
- Gibbs Richard A.
- Gilbert James
- Gingeras Thomas R.
- Gingeras Thomas R.
- Gingeras Thomas R.
- Giresi Paul G.
- Giresi Paul G.
- Glass Christopher K.
- Gnerre Sante
- Goldman Nick
- Goldy Jeff
- Good Peter J.
- Graves Tina
- Green Eric D.
- Green Eric D.
- Green Roland D.
- Greenbaum Jason A.
- Guan Xiaobin
- Guigó Roderic
- Guigó Roderic
- Guigó Roderic
- Guyer Mark S.
- Hackermüller Jörg
- Haidar Jaafar N. S.
- Halees Anason
- Hallgrímsdóttir Ingileif B.
- Hansen Nancy F.
- Hardison Ross C.
- Hardison Ross C.
- Hardison Ross C.
- Harrow Jennifer
- Harte Rachel A.
- Hartman Stephen
- Haussler David
- Haussler David
- Hawrylycz Michael
- Hayashizaki Yoshihide
- Haydock Andrew
- Heintzman Nate
- Henrichsen Charlotte N.
- Hertel Jana
- Hillman-Jackson Jennifer
- Hinrichs Angie S.
- Hirsch Heather A.
- Hirsch Heather A.
- Hofacker Ivo L.
- Holmes Ian
- Holroyd Nancy
- Hon Gary
- Hoon Kim Tae
- Hou Minmei
- Huang Haiyan
- Hubbard Tim
- Human Genome Sequencing Center* Baylor College of Medicine
- Humbert Richard
- Huppert Julian
- Idol Jacquelyn R.
- Inman David
- Iyer Vishwanath R.
- Jaffe David B.
- James Keith D.
- James Keith D.
- Jiang Huaiyang
- Jiang Nan
- Johnson Brett E.
- Johnson Ericka M.
- Kai Chikatoshi
- Kapranov Philipp
- Kapranov Philipp
- Kapranov Philipp
- Karaöz Ulaş
- Karaöz Ulaş
- Karnani Neerja
- Karolchik Donna
- Kawai Jun
- Keefe Damian
- Keefe Damian
- Keefe Damian
- Kent W. James
- Kent W. James
- Kern Andrew D.
- Kim Jonghwan
- King David C.
- Koch Christoph M.
- Koch Christoph M.
- Komorowski Jan
- Korbel Jan
- Koriabine Maxim
- Kraus Peter
- Kuehn Michael S.
- Kuhn Robert M.
- Lagarde Julien
- Lander Eric S.
- Langford Cordelia F.
- Lee Charlie W.H.
- Lee Kirsten
- Lefebvre Gregory C.
- Lefebvre Gregory C.
- Lian Jin
- Lian Jin
- Lian Zheng
- Lieb Jason D.
- Lieb Jason D.
- Liefer Laura A.
- Lin Jane M.
- Lindblad-Toh Kerstin
- Lindemeyer Manja
- Liu Jun
- Lopez-Bigas Nuria
- Lowe Todd M.
- Luna Rosa
- Löytynoja Ari
- Maduro Valerie V.B.
- Malhotra Ankit
- Manzano Caroline
- Mardis Elaine R.
- Margulies Elliott H.
- Margulies Elliott H.
- Margulies Elliott H.
- Martin Joel D.
- Maskeri Baishali
- Massingham Tim
- Matthews Nicholas
- Mattick John S.
- McDowell Jennifer C.
- Miller Webb
- Missal Kristin
- Montoya-Burgos Juan I.
- Moqtaderi Zarmik
- Mullikin James C.
- Mullikin James C.
- Munn Kyle J.
- Muzny Donna M.
- Myers Richard M.
- Myers Richard M.
- Myers Richard M.
- Nagalakshmi Ugrappa
- Navas Patrick A.
- Nefedov Mikhail
- Neph Shane
- Neri Fidencio
- Newburger Peter
- Ng Patrick
- Nikolaev Sergey
- Nix David A.
- Noble William S.
- Noble William S.
- Oakland Research Institute* Children’s Hospital
- Oberley Matthew J.
- Ooi Hong Sain
- Osoegawa Kazutoyo
- Pachter Lior
- Pachter Lior
- Pardi Fabio
- Park Morgan
- Parker Stephen C. J.
- Patel Sandeep
- Patel Sandeep
- Paten Benedict
- Pedersen Jakob S.
- Qu Chunxu
- Rada-Iglesias Alvaro
- Ren Bing
- Reymond Alexandre
- Reymond Alexandre
- Richmond Todd A.
- Rogers Jane
- Rosenbloom Kate
- Rosenbloom Kate
- Rosenfeld M. Geoff
- Rosenzweig Elizabeth R.
- Rozowsky Joel
- Rozowsky Joel
- Rozowsky Joel
- Ruan Yijun
- Ruan Yijun
- Sabo Peter J.
- Sandelin Albin
- Sandstrom Richard
- Sekinger Edward A.
- Sekinger Edward A.
- Sequencing Program NISC Comparative
- Seringhaus Michael
- Shafer Anthony
- Shahab Atif
- Shahab Atif
- Shulha Hennady P.
- Sidow Arend
- Sidow Arend
- Siepel Adam
- Siepel Adam
- Singer Michael A.
- Smith Kayla
- Snyder Michael
- Snyder Michael
- Snyder Michael
- Sodergren Erica
- Squazzo Sharon
- Srinivasan K.G.
- Stadler Peter F.
- Stamatoyannopoulos John A.
- Stamatoyannopoulos John A.
- Stamatoyannopoulos John A.
- Stone Eric A.
- Stranger Barbara E.
- Struhl Kevin
- Struhl Kevin
- Struhl Kevin
- Stuart Rhona
- Sung Wing-Kin
- Sung Wing-Kin
- Sunyaev Shamil
- Swarbreck David
- Tammana Hari
- Tanzer Andrea
- Taylor Christopher M.
- Taylor Christopher M.
- Taylor James
- Taylor James
- Taylor James
- Taylor James
- Taylor Ruth
- Thakkapallayil Archana
- Thomas Daryl J.
- Thomas Daryl J.
- Thomas Daryl J.
- Thomas Daryl J.
- Thomas Pamela J.
- Thurman Robert E.
- Thurman Robert E.
- Tress Michael L.
- Trinklein Nathan D.
- Trumbower Heather
- Trumbower Heather
- Tullius Thomas D.
- Tullius Thomas D.
- Ucla Catherine
- Urban Alexander E.
- Ureta-Vidal Abel
- Valencia Alfonso
- Van Calcar Sara
- Vega Vinsensius B.
- Vetrie David
- Vetrie David
- Wadelius Claes
- Wallerman Ola
- Wang Kun
- Washietl Stefan
- Washietl Stefan
- Weaver Molly
- Wei Chia-Lin
- Wei Chia-Lin
- Weinstock George M.
- Weirauch Matthew T.
- Weissman Sherman
- Weissman Sherman
- Weng Zhiping
- Weng Zhiping
- Wetterstrand Kris A.
- Wheeler David A.
- Whelan Simon
- Wilcox Sarah
- Wilcox Sarah
- Wilson Richard K.
- Woodroffe Abigail
- Worley Kim C.
- Wu Jiaqian
- Wu Jiaqian
- Wyss Carine
- Xu Mousheng
- Xu Xiaoqin
- Yang Annie
- Yao Fei
- Yoshinaga Yuko
- Young Alice C.
- Yu Yong
- Yu1 Man
- Zhang Nancy R.
- Zhang Xiaoling
- Zhang Xueqing
- Zhang Zhengdong D.
- Zhao XiaoDong
- Zheng Deyou
- Zheng Deyou
- Zheng Deyou
- Zhu Baoli
- Zhu Zhou
- Zody Michael C.
- Zweig Ann S.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study
We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a number of evolutionary and computational analyses. Together, our results advance the collective knowledge about human genome function in several major areas. First, our studies provide convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts, including non-protein-coding transcripts, and those that extensively overlap one another. Second, systematic examination of transcriptional regulation has yielded new understanding about transcription start sites, including their relationship to specific regulatory sequences and features of chromatin accessibility and histone modification. Third, a more sophisticated view of chromatin structure has emerged, including its inter-relationship with DNA replication and transcriptional regulation. Finally, integration of these new sources of information, in particular with respect to mammalian evolution based on inter- and intra-species sequence comparisons, has yielded new mechanistic and evolutionary insights concerning the functional landscape of the human genome. Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function