German Federal Constitutional Court: German Data Retention Provisions Unconstitutional in Their Present Form; Decision of 2 March 2010, NJW 2010, p. 833.

This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.About one year after the European Court of Justice had handed down its notorious decision on the Data Retention Directive concerning telecommunications traffic data, it was for the German Federal Constitutional Court to take a final decision on the German implementation of the Directive. So far, the latter Court had only issued temporary injunctions restricting data retrieval by the public authorities. Now, the final ruling by the Court has been anxiously awaited since the complainants had not only challenged the German provisions implementing the Directive, but also the Directive itself. Thus, the question was raised whether the Court would finally, for the first time in its history, initiate a preliminary ruling procedure according to Article 267 of the Treaty on the Functioning of the European Union.Peer Reviewe

Per una pedagogia del dono

The act of giving, in a pedagogical point of view, interlaces often with the act of giving himself and with the free and responsable will of encountering the other by his humanity. The main characteristic of giving is the gratuitousness: the human being can be educated aim for freedom and generosity about being able to give and give himself without fee. He who instead receives the gift had to be grateful: the gratification takes shape as an essential element in the educational life of the subject

Economic Evaluation and Optimization of the Degree of Automation in Insurance Processes

In the context of value and customer orientation there are various requirements concerning the process – especially in insurance companies: processes are meant to be standardized, automated, and flexible. It is in question whether a fast and cheap automated processing is preferred to manual handling. For which claims and which process steps is it of economic value to have the flexibility and the competence and ability to solve problems of human operators at your disposal? Various combinations, representing different degrees of automation, are possible. The different degrees of automation for the processing of an insurance claims are compared and resulting cash flows are determined. It is essential to include all consequences that can be attributed to a single process and to consider customer reactions and restrictions to the capacity of processing. Instead of using heuristic rules to decide on automation in practice, here the decision is flexible and depends on the given situation. Viewing an aggregated number of insurance claims it is possible to deduce information about the performance of the process. The model is exemplarily illustrated with help of a part of the process for handling own damage glass claims

Abnormal connectional fingerprint in schizophrenia: a novel network analysis of diffusion tensor imaging data

The graph theoretical analysis of structural magnetic resonance imaging (MRI) data has received a great deal of interest in recent years to characterize the organizational principles of brain networks and their alterations in psychiatric disorders, such as schizophrenia. However, the characterization of networks in clinical populations can be challenging, since the comparison of connectivity between groups is influenced by several factors, such as the overall number of connections and the structural abnormalities of the seed regions. To overcome these limitations, the current study employed the whole-brain analysis of connectional fingerprints in diffusion tensor imaging data obtained at 3 T of chronic schizophrenia patients (n = 16) and healthy, age-matched control participants (n = 17). Probabilistic tractography was performed to quantify the connectivity of 110 brain areas. The connectional fingerprint of a brain area represents the set of relative connection probabilities to all its target areas and is, hence, less affected by overall white and gray matter changes than absolute connectivity measures. After detecting brain regions with abnormal connectional fingerprints through similarity measures, we tested each of its relative connection probability between groups. We found altered connectional fingerprints in schizophrenia patients consistent with a dysconnectivity syndrome. While the medial frontal gyrus showed only reduced connectivity, the connectional fingerprints of the inferior frontal gyrus and the putamen mainly contained relatively increased connection probabilities to areas in the frontal, limbic, and subcortical areas. These findings are in line with previous studies that reported abnormalities in striatal–frontal circuits in the pathophysiology of schizophrenia, highlighting the potential utility of connectional fingerprints for the analysis of anatomical networks in the disorder

NSF Supported Socio-Environmental Research: How Do Crosscutting Programs Affect Research Funding, Publication, and Citation Patterns?

Recognizing the continued human domination of landscapes across the globe, social-ecological systems (SES) research has proliferated, necessitating interdisciplinary collaborations. Although interdisciplinary research started gaining traction in academic settings close to 50 years ago, formal frameworks for SES research did not develop until the late 1990s. The first National Science Foundation (NSF) funding mechanism specifically for interdisciplinary SES research began in 2001 and the SES-specific Coupled Natural Human (CNH) Systems program began in 2007. We used data on funded NSF projects from 2000 to 2015 to examine how SES research was funded, where the research is published, and the scholarly impact of SES research. Despite specific programs for funding SES research within the NSF, this type of research also received funding from non-SES mission programs (e.g., Ecosystem Science constituted 19% of grants in our study, and Hydrology constituted 16% of grants). Although NSF funding for SES research originates from across programs, the majority of products are published in journals with a focus on ecological sciences. Grants funded through the Coupled Natural Human Systems programs were more likely to publish at least one paper that was highly interdisciplinary (Biological Sciences [BE-CNH] constituted 70% of grants in program, and Geosciences [GEO-CNH] constituted 48% of grants) than the traditional disciplinary programs (Ecology [ES], 35% and Hydrology, 27%). This result highlights the utility of these cross-cutting programs in producing and widely disseminating SES research. We found that the number of citations was higher in BE-CNH and ES than other programs, pointing to greater scholarly impact of SES research in these NSF programs. Through our research, we identified the need for institutions to recognize research products and deliverables beyond the “standard” peer-reviewed manuscripts, as SES and interdisciplinary research and unconventional research products (e.g., popular press articles, online StoryMaps, workshops, white papers) continue to grow and are important to the broader societal impact of these types of research programs. This project demonstrates that the outcomes and products of grants awarded through the NSF CNH programs are important to furthering SES research and the programs should be valued and expanded in the future

A blue light receptor that mediates RNA binding and translational regulation

Sensory photoreceptor proteins underpin light-dependent adaptations in nature and enable the optogenetic control of organismal behavior and physiology. We identified the bacterial light-oxygen-voltage (LOV) photoreceptor PAL that sequence-specifically binds short RNA stem loops with around 20 nM affinity in blue light and weaker than 1 µM in darkness. A crystal structure rationalizes the unusual receptor architecture of PAL with C-terminal LOV photosensor and N-terminal effector units. The light-activated PAL–RNA interaction can be harnessed to regulate gene expression at the RNA level as a function of light in both bacteria and mammalian cells. The present results elucidate a new signal-transduction paradigm in LOV receptors and conjoin RNA biology with optogenetic regulation, thereby paving the way toward hitherto inaccessible optoribogenetic modalities