917 research outputs found

    Development of the International Space Station (ISS) Fine Water Mist (FWM) Portable Fire Extinguisher ICES Abstract

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    NASA is developing a Fine Water Mist (FWM) Portable Fire Extinguisher (PFE) for use on the International Space Station. The International Space Station presently uses two different types of fire extinguishers: a water foam extinguisher in the Russian Segment, and a carbon dioxide extinguisher in the US Segment and Columbus and Kibo pressurized elements. Changes in emergency breathing equipment make Fine Water Mist operationally preferable. Supplied oxygen breathing systems allow for safe discharge of a carbon dioxide fire extinguisher, without concerns of the crew inhaling unsafe levels of carbon dioxide. But the Portable Breathing Apparatus (PBA) offers no more than 15 minutes of capability, and continued use of hose based supplied oxygen system increases the oxygen content in a fire situation. NASA has developed a filtering respirator cartridge for use in a fire environment. It is qualified to provide up to 90 minutes of capability, and because it is a filtering respirator it does not add oxygen to the environment. The fire response respirator cartridge does not filter carbon dioxide (CO2), so a crew member discharging a CO2 fire extinguisher while wearing this filtering respirator would be at risk of inhaling unsafe levels of CO2. FWM extinguishes a fire without creating a large volume of air with reduced oxygen and elevated CO2. The following paper will discuss the unique functional and performance requirements that have been levied on the FWM PFE. In addition, the NASA ISS specific fire standards will be described which were developed to establish acceptable extinguisher performance. The paper will also discuss the flight hardware design. The fin e water mist fire extinguisher has two major elements: (1) the nozzle and crew interface, and (2) the tank. The nozzle and crew interface have been under development for several years. They have gone through several design iterations, and have been part of more than 400 fire challenge and spray characterizations. The crew and vehicle interface aspects of the design will use the heritage of the CO2 based Portable Fire Extinguisher, to minimize the disruption to the crew and integration impacts to the ISS. The microgravity use environment of the system poses a set of unique design requirements specifically for the tank. The nozzle requirements drive a tank pressure that is 2-5 times higher than any commercially available water mist systems. Microgravity requires deliberate separation of gas and water, facilitated by a bladder, a diaphragm, a piston, or separate tanks. This paper will describe status of the project to date, the design details of the tank and the nozzle, and discuss the trade studies that informed the decisions to select the tank and nozzle configuration

    Fermi surface reconstruction in FeSe under high pressure

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    We report Shubnikov-de Haas (SdH) oscillation measurements on FeSe under high pressure up to PP = 16.1 kbar. We find a sudden change in SdH oscillations at the onset of the pressure-induced antiferromagnetism at PP \sim 8 kbar. We argue that this change can be attributed to a reconstruction of the Fermi surface by the antiferromagnetic order. The negative dTcT_c/dPP observed in a range between PP \sim 8 and 12 kbar may be explained by the reduction in the density of states due to the reconstruction. The ratio of the transition temperature to the effective Fermi energy remains high under high pressure: kBTc/EFk_BT_c/E_F \sim 0.1 even at PP = 16.1 kbar.Comment: 12 pages , 10 figure

    Expression, functions, and new target genes of the transcription factor SOX10 in human melanoma

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    Implementation in nursing and midwifery. A scoping review

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    Hintergrund: Evidenzbasiertes Wissen steht im Pflege- und Hebammenbereich zunehmend zur Verfügung, wird aber nicht automatisch in die Praxis umgesetzt. Implementationsforschung gewinnt daher immer grössere Bedeutung. Die international verfügbaren Forschungsergebnisse zu den Faktoren, die zum Gelingen einer Implementation beitragen, sind bislang noch nicht genügend aufbereitet worden. Gegenstand des Artikels: Im vorliegenden Scoping Review wird der Frage nachgegangen, welche Arbeiten zur gelungenen Vorbereitung, Durchführung und Aufrechterhaltung von Interventionen im Bereich der Pflege- und Hebammenarbeit vorliegen. Methode: In der für Scoping Reviews vorgesehenen, systematischen Vorgehensweise wurden einschlägige Datenbanken durchsucht, um Reviews und Studien zur Implementationsforschung im Bereich Pflege und Hebammenarbeit aufzufinden. Der Auswahlprozess, der zur Trefferliste führte, und die Charakteristika der eingeschlossenen Studien werden in Abbildungen und Tabellen strukturiert aufbereitet. Ergebnis: In vier Reviews und 38 Studien, die den Einschlusskriterien entsprechen, werden verschiedene Faktoren mit gelungener Implementation verbunden. Für die eingeschlossenen Studien werden folgende vier Kategorien aufgestellt: (1) Arbeitsplatzkultur mit 16 Nennungen, (2) Leitungskultur: 28 Nennungen, (3) Ressourcen: 4 Nennungen und (4) Training mit 22 Nennungen. Je nach Phase der Implementation (Vorbereitung, Durchführung oder Aufrechterhaltung) kommt ihnen eine etwas andere Bedeutung zu. Zusammenfassung: Das Review bietet eine Orientierung im Feld der Implementationsforschung und zeigt Design, Thema und Ergebnis der eingeschlossenen Studien auf. Nur wenige Studien berücksichtigen relevante Theorien und zeigen den Einfluss sowohl der Forschenden als auch der Zielgruppe auf den Implementationsprozess oder die genaue Beschreibung der Umstände, in denen die Implementation stattfindet, auf. Background: Evidence-based expertise in nursing and midwifery is growing but is not automatically turned into practice. The importance of implementation research is therefore increasing. International research results on factors facilitating implementation have not yet been sufficiently presented. Objective: This scoping review will explore the findings on successful preparation, realisation and maintenance of interventions in nursing and midwifery. Method: Based on an existing systematic approach, relevant data bases were accessed to identify original studies relating to implementation research in nursing and midwifery. The process of study selection and the characteristics of the included studies were charted. Findings: In the four reviews and 38 studies which met the inclusion criteria, various factors leading to successful implementation are identified. Based on the included studies, four facilitating factors can be pinpointed: (1) workplace culture (16 entries), (2) leadership culture (28 entries), (3) resources (4 entries), and (4) training (22 entries). Depending on the specific phase of the implementation process (preparation, realisation, or maintenance), these factors will vary in importance. Conclusion: This scoping review provides an orientation for the field of implementation research and it maps the design, themes and results of the studies included. It should be noted that few studies take into consideration the relevant theories, as well as the influence that the researchers and the target group may have on the implementation process, or provide an exact description of the setting in which the implementation takes place

    A precision study of the fine tuning in the DiracNMSSM

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    Recently the DiracNMSSM has been proposed as a possible solution to reduce the fine tuning in supersymmetry. We determine the degree of fine tuning needed in the DiracNMSSM with and without non-universal gaugino masses and compare it with the fine tuning in the GNMSSM. To apply reasonable cuts on the allowed parameter regions we perform a precise calculation of the Higgs mass. In addition, we include the limits from direct SUSY searches and dark matter abundance. We find that both models are comparable in terms of fine tuning, with the minimal fine tuning in the GNMSSM slightly smaller.Comment: 20 pages + appendices, 10 figure

    DIGITALLY SOCIAL: REVIEW, SYNTHESIS, AND FUTURE DIRECTIONS FOR DIGITAL SOCIAL INNOVATION

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    Innovation contributes to solving the grand challenges of our time. Currently, two innovation research streams coexist mostly separated, without leveraging the potential at their interface: 1) Digital innovation using the generative power of digital technologies to trigger novel, incremental and/or disruptive solutions, and 2) social innovation accelerating sustainable development. To leverage the potential of digital innovations for reaching the goals of social innovation, we aim at advancing research on digital social innovation (DSI). A comprehensive literature review reveals 78 current DSI studies. We analyse them via a theory-based multidimensional framework. In that, we bring together both research streams, identify relevant research gaps at their interface, and derive a research agenda based on eight clear-cut research questions for DSI scholars. Our findings guide advancing DSI research and enable practitioners to leverage DSI in light of the current societal challenges

    Humorale und zelluläre Immunität nach Pertussis-Auffrischimpfung im Jugendalter

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    The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe

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    The preponderance of matter over antimatter in the early Universe, the dynamics of the supernova bursts that produced the heavy elements necessary for life and whether protons eventually decay --- these mysteries at the forefront of particle physics and astrophysics are key to understanding the early evolution of our Universe, its current state and its eventual fate. The Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed plan for a world-class experiment dedicated to addressing these questions. LBNE is conceived around three central components: (1) a new, high-intensity neutrino source generated from a megawatt-class proton accelerator at Fermi National Accelerator Laboratory, (2) a near neutrino detector just downstream of the source, and (3) a massive liquid argon time-projection chamber deployed as a far detector deep underground at the Sanford Underground Research Facility. This facility, located at the site of the former Homestake Mine in Lead, South Dakota, is approximately 1,300 km from the neutrino source at Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino charge-parity symmetry violation and mass ordering effects. This ambitious yet cost-effective design incorporates scalability and flexibility and can accommodate a variety of upgrades and contributions. With its exceptional combination of experimental configuration, technical capabilities, and potential for transformative discoveries, LBNE promises to be a vital facility for the field of particle physics worldwide, providing physicists from around the globe with opportunities to collaborate in a twenty to thirty year program of exciting science. In this document we provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess.Comment: Major update of previous version. This is the reference document for LBNE science program and current status. Chapters 1, 3, and 9 provide a comprehensive overview of LBNE's scientific objectives, its place in the landscape of neutrino physics worldwide, the technologies it will incorporate and the capabilities it will possess. 288 pages, 116 figure

    Opinia pielęgniarek na temat problemów pielęgnacyjnych w opiece nad pacjentami po udarze mózgu

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    Introduction. One of the most common causes of death, permanent disability in people aged over 40 is a stroke. The effective rehabilitation of stroke patients is affected by proper nursing care, as well as by assistance, presence and support for families of patients.Aim. The aim of this study was to obtain nurses’ opinion about the problems in the nursing care of patients after stroke.Material and Methods. The study was conducted with the participation of 60 respondents aged 23–58 years (average age: 38.1) including 4 men and 56 women. The respondents were of practitioners nurses at surgical and conservative wards in a healthcare facility in Silesia. The research tool was a questionnaire completed voluntarily by respondents, ensuring anonymity.Results. According to 85% of the respondents the most common problems that emerged during the nursing care of patients after stroke consisted of mental disorders occurring in patients. Then, performance of the toilet of the whole body of the patient (21.6%), education of the patients and their families (21.6%) and taking actions against anti-bedsore (18.3%). The fewest problems in nursing care accounted for oral feeding of patients (6.6%) and the situation in which the patient experienced pain (3.3%). Whereas feeding the patient through the tube and participation in pharmacotherapy was not the reason for problems that arise in the care of patients after stroke.Conclusions. 1) Working conditions of nurses at profile conservative and surgical wards, where hospitalized patients are of III and IV category of care contribute to the formation of significant physical and psychological burdens of this professional group, which reduces efficiency and thus reduces job satisfaction. 2) For the study group, the greatest problems of nursing are patients with mental disorders, education of the patients and their families and the performance of the patient’s whole body toilet. They hinder the care of the patient after a stroke. 3) The occurrence of adverse events did not constitute, according to the study group, a problem in patient care, so this perception of the study group points to the emerging syndrome of ‘burnout’. This may entail negative consequences in patient’s care, who need appropriate and comprehensive care after stroke. (JNNN 2017;6(2):73–80)Wstęp. Jedną z najczęstszych przyczyn śmierci, trwałego kalectwa i niepełnosprawności u osób powyżej 40 roku życia jest udar mózgu. Na efektywną rehabilitację pacjentów po udarze mózgu niewątpliwie wpływa odpowiednia opieka pielęgniarska, jak również pomoc, obecność i wsparcie rodzin pacjentów.Cel. Celem badań było pozyskanie opinii pielęgniarek na temat problemów w opiece pielęgnacyjnej nad pacjentami po przebytym udarze mózgu.Materiał i metody. Badanie zostało przeprowadzone z udziałem 60 osób w wieku 23–58 lat (średnia wieku: 38,1), w tym 4 mężczyzn i 56 kobiet. Respondentami były osoby wykonujące zawód pielęgniarza/pielęgniarki na oddziałach zabiegowych i zachowawczych w placówce służby zdrowia na terenie województwa śląskiego. Narzędziem badawczym był kwestionariusz dobrowolnie wypełniony przez respondentów, zapewniając im anonimowość.Wyniki. Według 85% respondentów najczęstszymi problemami, jakie powstają podczas sprawowania opieki pielęgniarskiej nad chorymi po przebytym udarze mózgu to obecne u pacjentów zaburzenia psychiczne. Następnie wykonywanie toalety całego ciała pacjenta (21,6%), edukacja pacjenta i jego rodziny (21,6%) oraz podejmowanie działań przeciwodleżynowych (18,3%). Najmniej problemów opiece pielęgniarskiej stanowiło karmienie doustne chorego (6,6%) oraz sytuacja, w której pacjent doświadczał dolegliwości bólowych (3,3%). Natomiast karmienie pacjenta przez zgłębnik i udział w farmakoterapii nie było powodem pojawiających się problemów w sprawowaniu opieki nad pacjentami po udarze mózgu.Wnioski. 1) Warunki pracy pielęgniarek na oddziałach zachowawczych i chirurgicznych, w których hospitalizowani są pacjenci III i IV kategorii opieki przyczyniają się do powstawania znaczących obciążeń fizycznych i psychicznych tej grupy zawodowej, co zmniejsza skuteczność, a tym samym zmniejsza satysfakcję z pracy. 2) W badanej grupie najwięcej problemów pielęgniarskich dotyczyło pacjentów z zaburzeniami psychicznymi i agresywnymi, edukacja pacjenta i jego rodziny oraz wykonywanie toalety całego ciała pacjenta. Te problemy znacząco utrudnią opiekę nad pacjentami po udarze mózgu. 3) Występowanie zdarzeń niepożądanych nie stanowi według badanej grupy problemu w opiece nad pacjentem, zatem takie postrzeganie badanej grupy wskazuje na pojawiający się syndrom ‘wypalenia zawodowego’. Może to nieść za sobą negatywne skutki w opiece nad pacjentami, którym niezbędna jest właściwa i kompleksowa pielęgnacja po przebytym udarze mózgu. (PNN 2017;6(2):73–80

    Domestic hot water systems in well-insulated residential buildings:A comparative simulation study on efficiency and hygiene challenges

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    Domestic hot water (DHW) is essential for daily life, yet the production can be energy intensive. Advances in building insulation reduced space heating demand, while DHW energy demand remained constant or even increased. The need for a higher proportion of renewable heat amplifies the conflict in DHW systems between energy efficiency, hygiene, and comfort, since high temperatures are required for hygienic purposes. Thus, developing DHW systems efficiently utilising renewable heat without excessive temperature requirements is essential. This paper reviews efficiency and hygiene challenges in DHW systems and assesses proposed solutions through comparative simulations in well-insulated residential buildings. Results show higher efficiencies in decentralised than centralised DHW systems. However, even in decentralised systems the necessity for circulation is a significant limitation. Lowering DHW temperature or transitioning to decentralised systems significantly reduces final energy demand, improves heat pump performance and increases the renewable heat share. Reducing DHW temperature from 60 to 50 °C increases stagnation periods in lower temperature intervals (22–34 °C) in warm water pipes. The study indicates significant potential to increase system efficiency and reduce final energy demand in decentralised or low-temperature DHW systems and introduces a novel method to compare conditions with regard to hygiene of DHW system simulations.</p
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