PENGARUH TINGKAT INFLASI, SUKU BUNGA BI, DAN NILAI TUKAR RUPIAH TERHADAP RETURN ON ASSET PERBANKAN

ABSTRACT: This research aims to find out how inflation, BI interest rates, and rupiah exchange rates affect the return on assets of persero banks in Indonesia. The method used in this research is descriptive and verifikative research method. The data was obtained from the financial statements of persero banks, consisting of Bank Mandiri, Bank Tabungan Negara, Bank Negara Indonesia, and Bank Rakyat Indonesia which were published on the official website of the Financial Services Authority during the quarter of 2017 to the quarter of 2019. Sampling in this study is based on saturated sampling techniques, i.e. all members of the population are sampled. The data in this research is processed using SPSS software. Data processing and analysis techniques use multiple regression analysis. The results of this study showed that together (simultaneously) independent variables of Inflation Rate, BI Interest Rate, and Rupiah Exchange Rate had a significant effect on Bank Persero's ROA in Indonesia in 2017-2019. The test results partially showed that the Variable Inflation Rate negatively and significantly affects return on assets at the persero banks registered with the Financial Services Authority for the period 2017-2019, bi interest rate variables have no effect on Return On Assets on persero banks registered with the Financial Services Authority for the period 2017-2019, rupiah exchange rate variables have a positive and significant effect on Return On Assets on persero banks registered with the Financial Services Authority for the period 2017-2019. Based on the test results determining the amount of coefficient of determination of 18% while the remaining 82% is explained by other variables that are not included in the regression model equation.Keywords: Inflation Rate, Bi Interest Rate, Rupiah Exchange Rate, Return On Assets ABSTRAK: Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh inflasi, suku bunga BI, dan nilai tukar rupiah terhadap return on asset bank persero yang ada di Indonesia. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif dan  verifikatif. Data diperoleh dari laporan keuangan bank persero, yang terdiri dari Bank  Mandiri, Bank Tabungan Negara, Bank Negara Indonesia, dan Bank Rakyat Indonesia yang publikasi di website resmi Otoritas Jasa Keuangan selama triwulan tahun 2017 sampai dengan triwulan tahun 2019. Pengambilan sampel dalam penelitian ini didasarkan pada teknik sampling jenuh, yaitu semua anggota populasi dijadikan sampel. Data dalam penelitian ini diolah menggunakan software SPSS. Teknik pengolahan dan analisis data menggunakan analisis regresi berganda. Hasil dari penelitian ini menunjukkan hasil bahwa secara bersama-sama (simultan) variabel independen Tingkat Inflasi, Suku Bunga BI, dan Nilai Tukar Rupiah berpengaruh signifikan terhadap ROA Bank Persero di Indonesia tahun 2017-2019. Hasil pengujian secara parsial menunjukkan hasil bahwa variabel Tingkat Inflasi berpengaruh negatif dan signifikan terhadap Return On Asset pada bank persero yang terdaftar di Otoritas Jasa Keuangan periode 2017-2019, variabel Suku Bunga BI tidak memiliki pengaruh terhadap Return On Asset pada bank persero yang terdaftar di Otoritas Jasa Keuangan periode 2017-2019, variabel Nilai Tukar Rupiah berpengaruh positif dan signifikan terhadap Return On Asset pada bank persero yang terdaftar di Otoritas Jasa Keuangan periode 2017-2019. Berdasarkan hasil uji  determinasi besarnya koefisien determinasi sebesar 18% sedangkan sisanya 82% dijelaskan oleh variabel lain yang tidak dimasukkan dalam persamaan model regresi.Kata Kunci: Tingkat Inflasi, Suku Bunga BI, Nilai Tukar Rupiah, Return On Assets

Antiproliferative Activity of Black Seed (Nigella Sativa) on 7,12-dimethylbenz-[a]antracene (DMBA) Induced Mice Lung Cell

Lung cancer is the leading cause of death in the world. Nigella sativa is a plant that has an anticancer activity. Previous research showed that the chloroform extract of N. sativahave cytotoxic effect on T47D cells. This study aimed to observe the effect of cloroform extract of N. sativaseed (NSS) on mice lung cell after initiation of 7,12-dimethylbenz [a] anthracene. Sprague Dawleystrain female rats were divided intofive groups. Each group consisted of 12 rats. The experiment consisted of five mice groups, corn oil as a solvent control group, the DMBA dose 20 mg/kgBW p.o. twice a week during five weeks, DMBA+NSS dose 250 mg/kgBW, DMBA+NSS dose 500 mg/kgBW, and DMBA+NSS dose 750 mg/kgBW. Extract which was dissolved into corn oil was administered daily by the oral route 1 week before and during the DMBA induction. At the end of the study, the experimental mice were sacrified and colon organs were collected and then stained with Haematoxylin and Eosin (H&E) and AgNOR method. H&E staining showed there was a decrease damage inthe treatment group compare with DMBA group. In AgNOR staining result showed mAgNOR value in DMBA group was 1.47±0.558, in extract group (250, 500 and 750mg/kgBB) was 0.44±0.172, 1.38±0.140 and 1.25±0.164 respectively and in corn oil group was 0.65±0.050. The results showed that N. sativareduced the damage of colon cells and inhibit colon cell proliferation on mice induced DMBA. This study indicated that N. sativacan be developed into a chemopreventive agent for lung cancer

Perbedaan Orientasi Keberagamaan Pada Siswa Santri Pondok Pesantren Tradisional dan Siswa Sekolah Islam Swasta

This study aims to understand and describe the religious orientation of which is owned by a traditional boarding school students and students of private Islamic schools. This research was conducted in two places, namely SMA Muhammadiyah 2 Surakarta and Traditional Pondok Pesantren Al-Mu'min Sragen. Research subjects in this study of 100 people with 50 high school students Muhammadiyah 2 Surakarta and 50 boarding school students of Al-Mu'min Sragen. Sampling was conducted by random sampling technique. The method used in this penlitian is a quantitative method by using religious orientation scale. This research data analysis techniques using independent sample t-tests. Based on the results of independent testing of samples t-test t-test values obtained at t = -0.399 with coefficient sig = 0.217 (p> 0.005) which means there is no difference in the orientation of traditional religious boarding school students and students of private Islamic schools. Subjects in this study had a religious orientation is high

Antiproliferative Activity of Black Seed (Nigella sativa) on 7,12-dimethylbenz-[a]antracene (DMBA) Induced Mice Lung Cell

Lung cancer is the leading cause of death in the world. Nigella sativa is a plant that has an anticancer activity. Previous research showed that the chloroform extract of N. sativahave cytotoxic effect on T47D cells. This study aimed to observe the effect of cloroform extract of N. sativaseed (NSS) on mice lung cell after initiation of 7,12-dimethylbenz [a] anthracene. Sprague Dawleystrain female rats were divided intofive groups. Each group consisted of 12 rats. The experiment consisted of five mice groups, corn oil as a solvent control group, the DMBA dose 20 mg/kgBW p.o. twice a week during five weeks, DMBA+NSS dose 250 mg/kgBW, DMBA+NSS dose 500 mg/kgBW, and DMBA+NSS dose 750 mg/kgBW. Extract which was dissolved into corn oil was administered daily by the oral route 1 week before and during the DMBA induction. At the end of the study, the experimental mice were sacrified and colon organs were collected and then stained with Haematoxylin and Eosin (H&E) and AgNOR method. H&E staining showed there was a decrease damage inthe treatment group compare with DMBA group. In AgNOR staining result showed mAgNOR value in DMBA group was 1.47±0.558, in extract group (250, 500 and 750mg/kgBB) was 0.44±0.172, 1.38±0.140 and 1.25±0.164 respectively and in corn oil group was 0.65±0.050. The results showed that N. sativareduced the damage of colon cells and inhibit colon cell proliferation on mice induced DMBA. This study indicated that N. sativacan be developed into a chemopreventive agent for lung cancer

Psidium guajava leaves decrease arthritic symptoms in adjuvant-induced arthritic rats

BACKGROUND Guava is an herbal with proven antioxidant and anti-inflammatory properties. The aim of this study was to investigate the anti-arthritic activity of the ethanol extract of Psidium gujava leaves (EEPG) against complete Freund’s adjuvant (CFA) induced arthritis in rats. METHODS An experimental study was conducted on 40 male Wistar Sprague Dawley rats, which were divided into 5 groups. Each group was induced with 0.2 mL CFA (1 mg/mL) on day 1 and 0.1 CFA mL booster injection on day 5. Group I served as an arthritic control, group II received dexamethasone (6.75 mg.kg-1 orally), group III, IV and V received EEPG at oral doses of 250, 500, and 750 mg/kg BW, respectively, on days 14 to 28. Anti-arthritic activity was observed from the arthritis score, the paw circumference was measured on days 0, 1, 4, 8, 12, 16, 20, 24, and 28, the mobility score was determined on days 12 and 28, and the histolopathology of the knee joint was examined on day 29. RESULTS Ethanol extract of Psidium guajava leaves significantly suppressed the swelling of the paws in chronic phase based on increasing of edema (%), while starting on day 20. EEPG at 250 mg/kg was most effective in significantly reducing arthritis scores (p<0.05). Histopathological examination showed repair of the knee joint synovial membrane and cartilage.   CONCLUSIONS Psidium guajava leaf extract is effective in decreasing the inflammatory response and arthritic symptoms in rats with adjuvant-induced arthritis. Psidium guajava leaves can be developed into an alternative anti-arthritis treatment

THE INCIDENCE OF LIVER FIBROSIS BASED ON NON-INVASIVE MARKERS AND HEPATOTOXIC DRUG USED IN HEPATITIS B PATIENTS

Objective - The development of hepatitis B virus infection can lead to the asymptomatic liver fibrosis which is reversible, but can develop into cirrhosis or even carcinoma. Hence, laboratory markers are needed to acquire the incidence of fibrosis such as by using AST-to-Platelet Ratio Index (APRI), Fib-4, AST-ALT Ratio (AAR), Age-Platelet (AP) index, and Pohl score. The use of hepatotoxic drug is commonly found in hepatitis B patients that might increase the risk of liver damage. This study aimed to determine the prevalence of liver fibrosis and to discover the use of hepatotoxic drug in hepatitis B patients at Prof. Dr. Margono Soekardjo Purwokerto General Hospital.Methods - This study used total sampling methods with descriptive qualitative and quantitative analysis. The source of data was medical records of hepatitis B patients from January 2012 to August 2013.Results - The result showed that from 25 hepatitis B patients, the incidence of liver fibrosis was found in 8% patients based on APRI, 44% based on Fib-4, 60% based on AAR, 52% based on AP index, and 28% based on Pohl score. There were 12 kinds of hepatotoxic drugs with ranitidine (60%) as the drug most widely used and most of them used one kind of hepatotoxic drug.Conclusions – Our study found that the incidence of liver fibrosis was found in hepatitis B patients which was measured based on APRI, Fib-4, AAR, AP index and Pohl score, beside that the use of hepatotoxic drug was commonly found among those patients

تطبيق وسائل التعليم لوحة النشرات "Bulletin Board " لتدريس مهارة القراءة

The ability of students will increasingly decline if the cause is not known. One of the impacts is that students' potential is left behind when learning Arabic. This is what makes it the task of educators to understand what methods should be used for teaching and learning activities. This study aims to help them get to know Arabic for students, and to develop the process of teaching Arabic by using the Bulletin Board media on maharoh qiro'ah. The target sample is class X Mtsn Jabal Nur Sidoarjo through a qualitative approach method. The results of this study are the use of media to facilitate the process of class X students of Mtsn Jabal Nur Sidoarjo learning Arabic for students and developing the process of teaching Arabic by using bulletinboards and developing and adding to the treasures of knowledge in the field of language. The use of bulletinboard media is a used to show examples of student work, charts, pictures, posters and objects in 3D. With this media, it is hoped that it can increase the innovation and creativity of educators in helping the teaching and learning process to be more interesting and easy to understand for students at Mtsn Jabal Nur Sidoarjo

Zingiber officinale, Piper retrofractum and Combination Induced Apoptosis and p53 Expression in Myeloma and WiDr Cell Lines

In previous studies, Zingiber officinale, Piper retrofractum, and the combination showed cytotoxic activity, induced apoptosis, and p53 expression of HeLa, T47D, and MCF-7 cell lines. This study was conducted to investigate the cytotoxic and apoptotic activity of Zingiber officinale (ZO), Piper retrofractum (PR), and the combination as well as their effect to p53 expression on Myeloma and WiDr cells. The powder of ZO, PR, and ZO + PR combination (1:1) were macerated with 96% ethanol for 3 x 24 hours. MTT cytotoxic assay was performed on Myeloma and WiDr cell lines. Apoptotic cells were stained with ethidium bromide and acridine orange. Imunohistochemical expression of p53 was examined on Myeloma and WiDr cell lines. Doxorubicin was used as positive control in all assays. Results showed that ZO, PR, and ZO + PR combination had cytotoxic activity on Myeloma cells with IC50 of 28, 36, and 55 mg/ml respectively and WiDr cell lines with IC50 of 74, 158, and 64 mg/ml respectively, induced apoptotic activity, and increased p53 expression on Myeloma and WiDr cells. These results suggest that ZO, PR, and their combination induced Myeloma and WiDr cells in apoptosis through p53 expression

Hubungan antara Faktor Risiko Osteoartritis dan Profil Terapi Obat terhadap Status Fungsional pada Pasien Osteoartritis Lutut (Studi dilakukan di RSI Aisyiyah Malang dan RS Brawijaya Tingkat III Surabaya)

Latar belakang : Osteoartritis lutut dapat dipengaruhi oleh faktor penuaan, jenis kelamin perempuan, indeks massa tubuh >25kg/m², dan aktivitas fisik berat dapat menurunkan status fungsional. Namun, dapat diminimalisir dengan pemberian terapi obat. Status fungsional dapat diukur dengan western ontario and mcmaster universities osteoarthritis index (WOMAC). Tujuan : Untuk menganalisis hubungan antara faktor risiko osteoartritis dan profil terapi obat terhadap status fungsional. Metode : Observasional analitik dengan pendekatan cross-sectional menggunakan data primer dan sekunder pada pasien osteoartritis lutut di Rumah Sakit Islam Aisyiyah Malang dan Rumah Sakit tingkat III Brawijaya Surabaya yang memenuhi kriteria inklusi. Analisis data menggunakan uji korelasi Somer’s dan Lambda. Hasil : Dari 44 responden diperoleh hampir setengah pasien memiliki status fungsional derajat sedang (47,7%). Mayoritas berusia >55 tahun (38,5%) yang didominasi oleh perempuan (88,6%) dengan obesitas (63,6%) dan aktivitas fisik berat (54,5%), serta pasien dengan terapi obat tunggal secara oral (36,4%). Usia (p=0,040) memiliki hubungan terhadap status fungsional. Jenis kelamin (p=0,073), indeks massa tubuh (p=0,356), aktivitas fisik (p=1,000) dan profil terapi obat (p=0,642) tidak memiliki hubungan terhadap status fungsional. Kesimpulan : Hasil penelitian menunjukkan terdapat hubungan antara usia dengan status fungsional serta tidak terdapat hubungan antara jenis kelamin, indeks massa tubuh, aktivitas fisik, dan profil terapi obat dengan status fungsional pada pasien osteoartritis lutut