Hubungan Tingkat Kedisiplinan Penggunaan Alat Pelindung Diri (APD) Terhadap Kondisi Kesehatan Kerja Karyawan Unit Fiber Glass PT Industri Kereta Api (INKA) Madiun

PT. INKA merupakan perusahaan yang bergerak dibidang industri gerbong kereta api. Salah satu unit dalam pekerjaan produksi kereta api adalah unit Fiber Glass. Tujuan penelitian ini untuk mengetahui hubungan tingkat kedisplinan penggunaan APD terhadap kondisi kesehatan. Penelitian ini menggunakan rancangan observasi dengan pendekatan Cross Sectional. Subjek penelitiannya adalah semua tenaga kerja bagian produksi yang berjumlah 42 orang dengan total sampling dengan jenis kelamin laki-laki. Data disajikan dalam bentuk tabulasi dan untuk mengetahui perbedaan tingkat kedisiplinan terhadap kondisi kesehatan menggunakan uji statistik Chi square. Hasil uji statistik Chi square menunjukkan bahwa nilai p adalah 0,000 (p<0,05) yang berarti ada pengaruh yang signifikan antara tingkat kedisiplinan penggunaan APD terhadap kondisi kesehatan kerja karyawan. Dari penelitian ini disimpulkan bahwa tingkat kedisiplinan penggunaan APD berhubungan terhadap kondisi kesehatan kerja. Sehingga bagi pekerja sebaiknya menggunakan APD saat bekerja agar kondisi kesehatan kerja karyawan tetap sehat

Kuliah Kerja Nyata (KKN) di Desa Bendungan Kabupaten Kulon Progo Provinsi Daerah Istimewa Yogyakarta

The 78th community service (KKN) was conducted in several villages in KulonProgo and GunungKidul Regencies. Authors were in group 87 and stationed in Bendungan Village, KulonProgo. This Community Service Program is focused on developing the potential of villages in the midst of the Covid-19 pandemic. Considering the agricultural background of the Bendungan village residents, programs about the farming, group 87 made a program about the introduction of organic fertilizers and the cultivation of Cavendish Banana. This program can help the local community's economy which is currently declining due to restrictions in carrying out activities amid this pandemic. Cavendish Banana has a fairly high value in the market and is also in great demand from consumers. Apart from developing the village's potential, a program in the form of a pocket book about new normal was arranged. This pocket book contains insights about new normal and new way of life, for example using a mask when traveling, regular hand wash, and always carrying a hand sanitize

The application of society 5.0 community service in Kulon Progo district

Academic community service (KKN – kuliah kerja nyata) normally involves on-field activities and interaction between students and local communities. The emerge of covid-19 pandemic led to social distancing, a less ideal situation for on-field community service. Meanwhile, the advance of information technology brought society toward the fifth era. At this situation, the concept of society 5.0 was applied on community service conducted in Kulon Progo district, Yogyakarta. Programs dedicated to improve local community were arranged without direct contact with community members, but utilizing online information to identify the potentials in the location under study and challenges faced by the community. Through literature study, proposed improvement on the potentials and solutions for the problems were developed. The results were presented as ebook or video offering educative and informative contents that can be beneficial for community empowerment

STATUS IDENTITAS REMAJA AKHIR : HUBUNGANNYA DENGAN GAYA PENGASUHAN ORANGTUA DAN TINGKAT KENAKALAN REMAJA

Abstract This research aims to find out whether or not there is a relationship between identity status late adolescent with parenting style and the level of juvenile delinquency. This research was conducted at the Faculty of Educational Sciences Campus with a population of UNESA subject prospective students and first year student who comes from Gresik, Bangkalan, Mojokerto, Surabaya, Sidoarjo and Lamongan. This research uses a quantitative approach is descriptive and korelasional. Data collection using the 3 question form with the analysis of the coefficient of contingency. From this research found a significant relationship between parenting style idetity status by 70 %. For the identity of the juvenile status is also a significant relationship exists at 63%. Descriptively found that the frequency of sample types more authoritative parenting style much achieved identity status compared with other parenting styles. At the level of delinquency was also found that the sample with the identity achieved status did little to medium to heavy levels of delinquency. Keywords : identity status, parenting style, the level of juvenile deliquency, late adolescent Abstrak Penelitian ini bertujuan untuk mengetahui ada tidaknya hubungan antara status identitas remaja akhir dengan gaya pengasuhan orangtua dan tingkat kenakalan remaja. Penelitian ini dilakukan di Fakultas Ilmu Pendidikan kampus UNESA dengan populasi subjek calon mahasiswa dan mahasiswa tahun pertama yang berasal dari Gresik, Bangkalan, Mojokerto, Surabaya, Sidoarjo dan Lamongan. Penelitian ini menggunakan pendekatan kuantitatif secara deskriptif dan korelasional. Pengumpulan data menggunakan 3 angket dengan analisis koefisien kontingensi. Hasil penelitian menemukan adanya hubungan yang signifikan antara status idetitas dengan gaya pengasuhan sebesar 70%. Untuk status identitas dengan kenakalan juga terdapat hubungan yang signifikan sebesar 63%. Secara deskriptif ditemukan bahwa frekuensi sampel jenis gaya pengasuhan otoritatif status identitasnya lebih banyak yang tercapai dibandingkan dengan gaya pengasuhan orangtua yang lain. Pada tingkat kenakalan juga ditemukan bahwa sampel dengan status identitas tercapai sedikit yang melakukan tingkat kenakalan menengah hingga berat. Kata kunci : status identitas, gaya pengasuhan, tingkat kenakalan, remaja akhi

ELECTROSPUN BIOMATERIALS AND RELATED TECHNOLOGIES

Electrospun Biomaterials and Related Technologies is a multi-contributed book containing review articles from worldwide authors with industry and academic background. This book is aimed to deliver a compiled overview in biomaterials electrospinning, including strategies, relevant technologies, and state-of-the-art research. The editor, Jorge Almodovar, has chemical engineering background with extensive research experiences and focus on engineering of biomimetic materials. The book consists of nine chapters in 282 content pages. Arranged in a concise format, it delivers a comprehensive but not exhaustive reading text. The chapters cover broad range of topics in electrospinning field, including process reproducibility and robustness, fibrous collagen scaffold, cellulose-based biomaterials, biopolymer nanofibres, green electrospinning, electrospun materials for cancer research, nanofibrous nerve conduits, scaffold for retinal tissue engineering, and smart material. These topics are mainly related to biomedical applications, but studies on environmental engineering are also conferred

Pemanfaatan Kelapa dan Pemberdayaan Potensi Desa sebagai Desa Wisata Berbasis Kearifan Lokal

Giripeni Village is one of the villages in Wates District, Kulon Progo Regency. Giripeni village is on the outskirts of the city, the area is mostly rice fields. Most of the people work as farmers and breeders. The availability of abundant foodstuffs such as grass and secondary crops is used to raise livestock. Giripeni Village has a lot of potential that can be developed, so that it becomes a tourist village to attract the wider community, both nationwide and worldwide from Giripeni Village. The development of this tourism village is one of the rural tourism developments which is expected to become a sustainable tourism development in accordance with government policies in the tourism sector. On the other hand, during the Covid-19 epidemic, many workers lost their jobs and some required workers to do their work from home. Group 88 provides video on using coconut fruit, so that people in Giripeni village whose jobs are affected by the Covid-19 pandemic can remain productive even at home. The method provided to process the coconut involves a simple steps and efficient use of materials. The research was carried out through online observation. The data in this study are secondary data obtained from the Giripeni village website and secondary data obtained based on previous researc

Implikasi Putusan Mahkamah Konstitusi Nomor 85/PUU-XIV/2016 terhadap Praktek Persekongkolan Tender

Pada pokoknya, persekongkolan tender merupakan salah satu bentuk persekongkolan yang dilarang UU Nomor 5/1999 tentang Larangan Praktek Monopoli dan Persaingan Usaha Tidak Sehat dan juga menjadi perkara yang paling sering diproses KPPU. Namun baik secara teoritis maupun praktik menimbulkan permasalahan yaitu karena adanya pemaknaan yang bias akan frasa “pihak lain” dalam Pasal 22 UU Nomor 5/1999. Hal inilah yang melatarbelakangi adanya pengujian Pasal 22 ke MK. Dalam penulisan ini yang dibahas yaitu bagaimana pengaturan persekongkolan tender menurut peraturan Perundang-undangan, bagaimanakah implikasi yuridis Putusan Mahkamah Konstitusi Nomor 85/PUU-XIV/2016 tentang pengujian Pasal 22 UU Nomor 5/1999 serta bagaimana analisis hukum terhadap pertimbangan hukum Putusan MK tersebut. Penelitian ini menggunakan penelitian yuridis normatif dimana obyek penelitian ini adalah peraturan Perundang-undangan dan Putusan MK. Dalam hal ini Penulis menyimpulkan, yaitu, Pertama, persekongkolan tender yang merupakan suatu bentuk kerja sama antara dua pihak atau lebih untuk menguasai pasar yang bersangkutan dan/atau memenangkan peserta tender yang mengakibatkan terjadinya persaingan USAha tidak sehat diatur secara eksplisit dalam Pasal 1 angka 8 dan Pasal 22 UU Nomor 5/1999 serta Peraturan KPPU Nomor 2/2010, Kedua, Implikasi yuridis Putusan MK Nomor 85/PUU-XIV/2016 bermanfaat untuk menjamin kepastian hukum dan keadilan bagi para pihak seperti pengusaha utamanya masyarakat. Untuk itu, perlu adanya harmonisasi antara satu peraturan dengan peraturan lainnya, pengujian UU terhadap UUD terkait pengaturan persekongkolan tender dalam persaingan USAha tidak sehat ataupun revisi terhadap UU Nomor 5/1999.Principally, tender conspiracy is one form of conspiracy that subjected by the Law No. 5/1999 on The Prohibition of Monopolistic Practices and Unfair Business Competition, and also as a type of case that frequently occurred and processed by the KPPU. However, in theory, and in practice, there are some issues that plague the regulation, because of the occurrence of bias and unclear interpretation of the phrases “other parties” contained in Article 22 of Law 5/1999. This interpretation issue then became the background in the petition for review of Article 22 to the Constitutional Court. This paper mainly discussed the regulation of tender conspiracy according to the existing Law, and also to study the juridical implications of Constitutional Court Decision Number 85/PUU-XIV/2016 concerning the review of Article 22 Law 5/1999. This paper also delves into the legal analysis of the court considered in the aforementioned Decision. This paper utilized the means of normative juridical research methodology, with the existing regulations and Constitutional Court Decision as the object of research. In the paper, the writer concludes that, first, tender conspiracy is a form of cooperation between one party or more to control particular market and/or to determine the awardees of tenders which may cause unfair business competition explicitly regulated in Article 1 number 8 and Article 22 Law 5/1999 and also the KPPU Regulation Number 2/2010, second, the juridical implications of Constitutional Court Decision Number 85/PUU-XIV/2016 was necessary in order to guarantee the equitable legal certainty and fairness toward all parties especially business practising citizens. Thus, there is a necessity to achieve harmony among these regulations, which can be obtained through the judicial review of laws against the Constitution concerning the regulations of tender conspiracy and by means of legislative revision toward Law 5/1999

Proposed solutions on waste issues in Kulon Progo regency through society 5.0 community service

Waste is a global environmental issue. The problem can be unique in each area and it can be organic or plastic. One of the solutions for waste problems is waste processing. In this article, community service on programs related to waste and environmental issues is presented. Due to covid-19 pandemic, community service was carried out with society 5.0 approach instead of with the traditional on-field. Waste problems in Kulon Progo regency were explored, particularly in Giripeni, Temon Wetan, Bendungan, and Kulwaru village. Through literature study, waste-related concerns in each village were explored, followed by the development of solution for each issue. Organic wastes could be processed into organic fertilizer and hand craft, while plastics could be an advantageous ingredient for making paving block. The outputs were arranged in educative and interesting ebooks for inspiring and encouraging positive activities for community empowerment

PENGARUH PEMBERIAN BISA NAJA SPUTATRIX TERHADAP KADAR INTERLEUKIN-2 SERUM DARAH MENCIT YANG DIINDUKSI BENZO(A)PYRENE

Cancer has become a global health problem arisen from exposure to benzo(a)pyrene. Interleukin-2 is one of immune system components believed to play roles in eradicating cancer. Cobra venom has antitumor effect and also contain protease which could boost up immune system. This research was aimed at analyzing Naja sputatrix venoms effect to increase interleukin-2 level in blood sera of mice induced by benzo(a)pyrene. Four group of Balb-C mice were used. The first group (control) and second group (treatment with Naja sputatrix venom) consist of 5 mices. There are 6 mices used in group 3 and 4, both were injected intramuscularly by benzo(a)pyrene (0,3L/0,01mL oleum oil) at day 1, 8 and 15. Three months after, observation was carried out to see changes occured in their liver and lungs. Naja sputatrix venom 0,1 mL (diluted in saline 1:100) was given to group 2 and 4 for 30 days. Blood was collected from all groups and centrifuge to form sera. Level of interleukin-2 in sera was measured by ELISA method. The results show that Group 2 has the highest mean level of interleukin-2 (136,837 pg/mL), and group 3 has the lowest (8,996 pg/mL). Level of interleukin-2 in group 4 is slightly higher than group 3 (10,632 pg/mL). Kruskal-Wallis analysis result come with Sig. 0,155; therefore shows no significance(p&gt;0,05). It is therefore concluded that Naja sputatrix venom do not increase interleukin-2 level in blood sera of mice induced by benzo(a)pyren

Ursolic Acid Enhances Doxorubicin Cytotoxicity on MCF-7 Cells Mediated by G2/M Arrest

Ursolic acid has been widely known to possess biological activity against numerous tumor cell lines. Previous studies revealed its cytotoxicity on several cancer cells in vitro by either inducing apoptosis or cell cycle modulation. This study was conducted to investigate ursolic acid’s cytotoxicity solely and in combination with a chemotherapeutic agent, doxorubicin, on MCF-7 breast cancer cells, followed by observation on its mechanism. Cytotoxicity of single and combinational treatment of ursolic acid and doxorubicin on MCF-7 breast cancer cells were conducted by using MTT assay. Single treatment was then evaluated by determining IC50 value, while combinational treatment was evaluated by analyzing cell viability and evaluating combination index (CI). To explore the mechanism underlying cytotoxic effect on respected cells, further analysis on cell cycle profile of single and combinational treatment was conducted by flow cytometry. Twenty four hours treatment of ursolic acid inhibited MCF-7 cells’ growth with IC50 value of 37 µM, while combinational treatment showed that several concentration combinations of ursolic acid and doxorubicin exhibited synergism of cytotoxic activity on MCF-7 cells, giving optimum CI value of 0.54. Flow cytometric analysis showed that combinational treatment induced G2/M arrest in MCF-7 cells. These results show that ursolic acid is promising to be developed as either single chemopreventive agent, or as doxorubicin’s co-chemotherapeutic agent in breast cancer treatment. Observation on the selectivity as part of safety aspect together with in silico, in vitro, and in vivo study on its molecular mechanism should be conducted.Keywords: ursolic acid, doxorubicin,co-chemotherapeutic agent, breast cancer, cell cycl