136 research outputs found

    Dret, Llei i Poder a la història dels Atrides segons P. P. Pasolini

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    This study means to research the sense — one of the senses— that Pasolini confers to Atridaes’ history, in his translation of the Orestea of Aeschylus (1960). Following the semantic developement of conceptual meaning such as Right, Law and Power, from Aeschylus to Pasolini, and through the analysis of the textual variations there emerges an original point of view. The principal meaning that underlines the translation is explicitly political and specifically marxist. Moreover, widening the investigation to other work of Pasolini, such as the Pilade (1967, an ideal sequel of the trilogy, completely dominated by a pessimistic — maybe nihilistic— perspective) or to the documentary film Appunti per un’Orestiade africana (1968-69, set in contemporary Africa), the analysis focuses on the principal difference between the ethical and political system of Aeschylus and that of Pasolini. The italian poet considers the Atridaes’ history as a symbolic possibility of a synthesis (the passage from the Erinies to the Eumenides, from the Irrational to the Rational without loosing the archaic point of the mythical past); but, in his text, we can clearly see his point of view, buried before in the original greek text: the synthesis — the Rational— is at the same time irrational and outreageous, still archaic but totally new. This synthetic possibility cannot exist in the contemporary world (capitalistic as it is and a world wich is based on consumerism). The drama of Orestes (and of all human beings) ends in the only way it can: the ethical and political disaster of the Pilade. If not we haveto move to another world, to another space/time situation, possibly the African one of the Appunti

    Usability testing of an e-learning resource designed to improve medical students' physical activity prescription skills: a qualitative think-aloud study.

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    OBJECTIVE: An e-learning resource (MEdic GAming, MEGA) was developed based on the contents of the Faculty of Sports and Exercise Medicine exercise prescription booklet. This study aimed to (i) explore medical students' perspectives of physical activity promotion and e-learning and (ii) investigate medical students' response to the design, content and usability of the MEGA e-learning resource. DESIGN: Qualitative think-aloud interview study. SETTING: A London medical school. PARTICIPANTS: 19 undergraduate medical students were interviewed using the think-aloud method while using the e-learning resource concurrently. RESULTS: In general, medical students felt current education on physical activity is inadequate and held a strong desire for more teaching on exercise medicine. Students believed the MEGA e-learning resource addressed a gap in their knowledge on physical activity but noted e-learning should not replace face-to-face teaching and suggested physical activity education would be best delivered through a blended learning approach. Students felt such an approach would allow better opportunity to practice physical activity counselling skills with patients while on clinical placement. Students' motivation to engage with the MEGA e-learning resource was positively impacted by aesthetically appealing design and interactive gamification elements such as self-assessment quizzes and visual progress tracking. CONCLUSION: Medical students value the role of physical activity in health but are disappointed by the lack of teaching within the current medical curriculum. E-learning resources, such as MEGA, which contain interactive features are a viable means to integrate physical activity into the undergraduate curriculum but should be supplemented by the opportunity to practice physical activity counselling in-person

    Integrating physical activity promotion into UK medical school curricula: testing the feasibility of an educational tool developed by the Faculty of Sports and Exercise Medicine.

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    Background: At present education on exercise medicine and physical activity (PA) promotion does not feature heavily within the medical curriculum. Objectives: The purpose of this study was to test the feasibility of a self-directed educational tool (Faculty of Sports and Exercise Medicine (FSEM) exercise prescription booklet) on medical students' understanding of PA in disease management. Methods: Students from 22 UK medical schools were invited to complete a brief online questionnaire before and after being provided access to the FSEM exercise prescription booklet. Results: A total of 205 students responded to the open invitation to participate. At baseline 59% of students agreed that PA promotion was an important part of a doctor's job with 86% agreeing that PA was important in the prevention of disease. However, confidence to prescribe PA and knowledge of chief medical officer's adult PA guidelines was low. Following use of the FSEM booklet students' (n=53) knowledge of PA guidelines and confidence to advise patients about PA significantly improved (p<0.05). Correct response answers to case scenarios covering PA in disease management (specifically osteoarthritis and cancer) also improved (32% and 44% increase, respectively, p<0.01). Conclusion: Self-guided educational tools have the potential to improve the exercise prescription skills of undergraduate medical students. Future research should compare different methods of delivering education on PA within medical schools to determine the most effective means of integrating PA into the curriculum

    Whole-body vibration decreases delayed onset muscle soreness following eccentric exercise in elite hockey players: a randomised controlled trial

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    Abstract Background Delayed onset muscle soreness (DOMS) is a common non-structural muscle injury which can disrupt training and impair performance in elite athletes. Vibration therapy reduces inflammation and improves neuromuscular efficiency, leading to reductions in pain and stiffness, and may be effective for the prevention or treatment of DOMS. However, the effect of whole-body vibration (WBV) used after sport in elite athletes has not been reported. Methods A randomised, controlled trial was performed. Participants were elite (national or international level) hockey players and underwent an eccentric exercise protocol previously shown to produce clinical DOMS. After exercise, one group underwent static stretching with WBV therapy, and the other performed stretching only. Baseline and serial post-exercise pain scores and measurements of quadriceps tightness were obtained. Results Eleven participants were recruited into each study arm. There were no significant differences in baseline group characteristics. Participants receiving WBV had significant reductions in both pain (p = 0.04) and quadriceps tightness (p = 0.02) compared with stretching only. Conclusions Post-exercise WBV is effective in elite hockey players to reduce DOMS after eccentric exercise. Elite athletes in multi-sprint sports are at risk of DOMS during training and competition, and its reduction could contribute to reduced injury risk and improved performance. This treatment modality is favourable because it can be incorporated with minimal disruption into the recovery section of existing training regimes. These findings may also be extrapolated to other multi-sprint sports

    Nuclear and chloroplast microsatellite diversity in Phaseolus vulgaris L. from Sardinia (Italy).

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    Studies of the level and the structure of the genetic diversity of local varieties of Phaseolus vulgaris are of fundamental importance, both for the management of genetic resources and to improve our understanding of the pathways of dissemination and the evolution of this species in Europe. We have here characterized 73 local bean populations from Sardinia (Italy) using seed traits and molecular markers (phaseolins, nuSSRs and cpSSRs). American landraces and commercial varieties were also included for comparison. We see that: (a) the Sardinian material is distinct from the commercial varieties considered; (b) the variation in the seed traits is high and it mostly occurs among populations (95%); (c) compared to the American sample and the commercial varieties, the Sardinian collection has a low level of diversity; (d) the majority ([95%) of the Sardinian individuals belong to the Andean gene pool; (e) the Sardinian material shows a strong genetic structure, both for cpSSRs and nuSSRs; (f) the nuSSRs and cpSSRs concur in differentiating between gene pools, but a lack of congruence between nuclear and chloroplast has been observed within gene pools; and (g) there are three putative hybrids between the Andean and Mesoamerican gene pools. Despite the relatively low level of diversity, which is probably due to a strong founder effect, the Sardinian landraces are worth being conserved and studied further because of their distinctiveness and because hybridization within and between the gene pools could generate variation that will be useful for breeding

    The Effect of Strength and Plyometric Training on Functional Dance Performance in Elite Ballet and Modern Dancers

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    Background: Ballet and modern dance are both art forms that require technique, artistry, grace and precision. Both dance forms require a degree of strength and muscular endurance for optimal performance. It is not known what value strength or plyometric training may have on functional dance performance. Objective: To systematically review the effects of strength and/or plyometric training on functional dance performance in elite ballet and modern dancers. Methods: A systematic review of literature indexed in the following databases: Medline, CINAHL, SportsDiscus, Physiotherapy Evidence Database (PEDro) and PubMed was conducted. The quality of the studies was graded using the PEDro Scale. Results: Eight studies satisfied the eligibility criteria and were included in this review. The studies\u27 population age range was 19?27?years. Methodological scores based on the PEDro scale were 4 to 6 out of 10. All of the included studies (100%) scored 4 out of 10 or higher on the PEDro scale. Strength training resulted in significant improvements in jump height (P? Conclusion: Moderate evidence indicates that supplementary strength training interventions via traditional resistance training or whole-body vibration methods and plyometric training interventions may increase certain dance-performance measures such as jump height and general aesthetic facility without changing certain anthropometric measures in elite ballet and modern dancers

    Metformin associated lactic acidosis: a case series of 28 patients treated with sustained low-efficiency dialysis (SLED) and long-term follow-up

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    Background: Metformin associated lactic acidosis (MALA) is a well-known serious side effect of biguanides. However, the best treatment strategy remains a matter of debate. In the last 14 years, we observed a significant increase in hospitalizations for MALA to our Center. We report the outcomes of our clinical and therapeutic approach. Methods: This is a single-center case series. Twenty-eight patients affected with MALA and acute kidney failure admitted between January 2000 and September 2014 were included. We analyzed comorbidities, laboratory tests and clinical parameters at admission, at 36 h and at discharge. All patients were treated with sustained low-efficiency dialysis (SLED) until normalization of serum lactate (&lt;= 3 mmol/L), bicarbonate (between 20 and 25 mmol/L) and potassium (between 4.0 and 5.1 mmol/L). Results: The mortality rate was 21.4%, with all of the events occurring within 24 h from admission, and before or during the first hemodialysis treatment. Precipitating causes included; acute dehydration (86.4%), systemic inflammatory response syndrome (SIRS) (57.1%), sepsis (10.7%), nephrolithiasis (14.6%) and exposure to iodinated contrast (7.1%). No further episodes of lactic acidosis were described after discontinuing the drug over a mean follow-up of 27.2 months. Furthermore, while in 2010, we had a peak incidence of MALA of 76.8 cases per 100,000 patients on metformin, this rate fell after an education campaign conducted by specialists on the proper usage of metformin in patients at risk of MALA. Although the fall in incidence after the educational program was not necessarily causal, in 2014 the incidence was 32.9/100,000. Conclusions: We report an improved mortality rate in patients affected with MALA and acute kidney injury treated with SLED compared with other series published in literature. Rapid introduction of effective hemodialysis is critical in improving outcomes

    Clinicopathologic predictors of renal outcomes in light chain cast nephropathy: a multicenter retrospective study

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    Light chain cast nephropathy (LCCN) in multiple myeloma often leads to severe and poorly reversible acute kidney injury. Severe renal impairment influences the allocation of chemotherapy and its tolerability; it also affects patient survival. Whether renal biopsy findings add to the clinical assessment in predicting renal and patient outcomes in LCCN is uncertain. We retrospectively reviewed clinical presentation, chemotherapy regimens, hematologic response, and renal and patient outcomes in 178 patients with biopsy-proven LCCN from 10 centers in Europe and North America. A detailed pathology review, including assessment of the extent of cast formation, was performed to study correlations with initial presentation and outcomes. Patients presented with a mean estimated glomerular filtration rate (eGFR) of 13 ± 11 mL/min/1.73 m2, and 82% had stage 3 acute kidney injury. The mean number of casts was 3.2/mm2 in the cortex. Tubulointerstitial lesions were frequent: acute tubular injury (94%), tubulitis (82%), tubular rupture (62%), giant cell reaction (60%), and cortical and medullary inflammation (95% and 75%, respectively). Medullary inflammation, giant cell reaction, and the extent of cast formation correlated with eGFR value at LCCN diagnosis. During a median follow-up of 22 months, mean eGFR increased to 43 ± 30 mL/min/1.73 m2. Age, β2-microglobulin, best hematologic response, number of cortical casts per square millimeter, and degree of interstitial fibrosis/tubular atrophy (IFTA) were independently associated with a higher eGFR during follow-up. This eGFR value correlated with overall survival, independently of the hematologic response. This study shows that extent of cast formation and IFTA in LCCN predicts the quality of renal response, which, in turn, is associated with overall survival.info:eu-repo/semantics/publishedVersio
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