40 research outputs found
Resistance Training for Patients with Rheumatoid Arthritis: Effects on Disability, Rheumatoid Cachexia, and Osteoporosis; and Recommendations for Prescription
The use of digitally altered photographs to assess stakeholder woodland cover preferences in internationally important cultural landscapes; a case study in the English Lake District National Park.
This project explores the effectiveness of digitally manipulated photographs for evaluating peoples' preferences towards woodland cover in an internationally important cultural landscape. A photograph of a well known English Lake District view was digitally altered to produce six images with greater or lesser amounts of woodland cover. Using an online survey, respondents were asked to identify which image represented current levels and which their preferred levels of cover. The responses were then related to the personal data of the respondents. 506 usable responses indicated a strong preference for increased woodland cover. Accurate identification of the location and cover levels was related to proximity of domicile, age and frequency of visit. The nearer respondents lived to the Lake District the greater the preference for increased cover. Employment, domicile, age, gender, settlement type and voluntary organisation data were recorded. Women were less extreme in their preferences than men and farmers tended towards open field perceptions and preferences. Photomanipulation is shown to be an effective tool for assessing preferences for degree of woodland cover and could be well applied to more representative data gathering than online survey
The 8-foot up and go test is the best way to assess physical function in the rheumatoid arthritis clinic
Objectives
RA is characterized by poor physical function, which compromises patients’ quality of life and outcome. Clinical assessment of function is usually performed using self-reported questionnaires, such as the Multi-Dimensional HAQ (MDHAQ) and the Short Form-36 (physical component) (SF36-PC). However, such subjective measures may not accurately reflect real functional status. This study aimed to determine: (i) which clinically practicable objective test best represents overall physical function; and (ii) the extent to which self-reported subjective functional measures reflect objectively assessed function.
Methods
Objective [isometric knee extensor strength, handgrip strength, sit-to-stands in 30 s, 8-foot up and go (8′UG), 50-foot walk (50′W) and estimated aerobic capacity (V̇O2max)] and subjective (MDHAQ and SF36-PC) measures of function were correlated with one another to determine the best overall test of functional status in 82 well-controlled RA patients (DAS28 (S.D.) = 2.8 (1.0)).
Results
In rank order of size, averaged correlations (r) to the other outcome measures were as follows: 8′UG: 0.650; 50′W: 0.636; isometric knee extensor strength: 0.502; handgrip strength: 0.449; sit-to-stands in 30 s: 0.432; and estimated V̇O2max: 0.358. The MDHAQ was weakly (0.361) and the SF36-PC moderately correlated (0.415) with objective measures.
Conclusion
Our results show that the most appropriate measure of objective physical function in RA patients is the 8′UG, followed by the 50′W. We found discordance between objectively and subjectively measured function. In clinical practice, an objective measure that is simple and quick to perform, such as the 8′UG, is advocated for assessing real functional status
Does an early home-based progressive resistance training program improve function following total hip replacement? Results of a randomized controlled study
CONSORT 2010 checklist. (DOC 219 kb
Efficacy of Nandrolone Decanoate in Treating Rheumatoid Cachexia in Male Rheumatoid Arthritis Patients
Muscle loss following a single high-dose intramuscular injection of corticosteroids to treat disease flare in rheumatoid arthritis patients
Can creatine supplementation improve body composition and objective physical function in rheumatoid arthritis patients? A randomised controlled trial.
OBJECTIVE: Rheumatoid cachexia (muscle wasting) in rheumatoid arthritis (RA) patients contributes to substantial reductions in strength and impaired physical function. The objective of this randomised control trial was to investigate the effectiveness of oral creatine (Cr) supplementation in increasing lean mass and improving strength and physical function in RA patients. METHOD: In a double-blind design, 40 RA patients, were randomised to either 12 weeks supplementation of Cr or placebo. Body composition (dual energy x-ray absorptiometry, DXA, and bioelectrical impedance spectroscopy, BIS), strength and objectively-assessed physical function were measured at: baseline, day 6, week 12 and week 24. Data analysis was performed by ANCOVA. RESULTS: Creatine supplementation increased appendicular lean mass (ALM; a surrogate measure of muscle mass) by 0.52 (± 0.13) kg (P = 0.004 versus placebo), and total LM by 0.60 (± 0.37) kg (P = 0.158). The change in LM concurred with the gain in intracellular water (0.64 ± 0.22 L, P = 0.035) measured by BIS. Despite increasing ALM, Cr supplementation, relative to placebo, failed to improve isometric knee extensor (P = 0.408), handgrip strength (P = 0.833), or objectively-assessed physical function (P's = 0.335 - 0.764). CONCLUSION: In patients with RA, creatine supplementation increased muscle mass, but not strength or objective physical function. No treatment-related adverse effects were reported suggesting that Cr supplementation may offer a safe and acceptable adjunct treatment for attenuating muscle loss; this treatment may be beneficial for patients suffering from severe rheumatoid cachexia. This article is protected by copyright. All rights reserved
Benefits of Exercise in Rheumatoid Arthritis
This paper aims to highlight the importance of exercise in patients with rheumatoid arthritis (RA) and to demonstrate the multitude of beneficial effects that properly designed exercise training has in this population. RA is a chronic, systemic, autoimmune disease characterised by decrements to joint health including joint pain and inflammation, fatigue, increased incidence and progression of cardiovascular disease, and accelerated loss of muscle mass, that is, “rheumatoid cachexia”. These factors contribute to functional limitation, disability, comorbidities, and reduced quality of life. Exercise training for RA patients has been shown to be efficacious in reversing cachexia and substantially improving function without exacerbating disease activity and is likely to reduce cardiovascular risk. Thus, all RA patients should be encouraged to include aerobic and resistance exercise training as part of routine care. Understanding the perceptions of RA patients and health professionals to exercise is key to patients initiating and adhering to effective exercise training