Pola Komunikasi Public Relation Officer Dalam Memepertahankan Citra PT. Lion Air Indonesia Cabang

Penelitian ini akan mendiskusikan isu-isu interen dan eksteren Perusahaan, motif yang di gunakan Public Relation Officer (PRO), cara yang di gunakan Public Relation Officer (PRO) untuk bersosialisasi dengan masyarakat, kesepahaman yang menghasilkan ketergantungan dari seluruh sub-sub sistem Perusahaan sehingga lahir keterkaitan yang menghasilkan simbiosis model bertujuan satu (Symbiote mutualisme), dan hambatan apa yang ditemukan dalam komunikasi organisasi oleh Public Relation Offecer (PRO) di PT. Lion Air Indonesia cabang Manado. Penelitian ini menggunakan jenis data kualitatif deskriptif yang memaparkan dengan jelas setiap fenomena yang terjadi. Dengan teori komunikasi organisasi Weick (Organisation Theory of Weick) penelitian ini berpendapat bahwa yang terjadi menerpa Perusahaan dapat dilihat dari perspektif fenomenologi, yaitu dimana setiap kejadian yang terjadi akan mengalami intepretasi lewat pengalaman-pengalaman setiap pribadi yang terikat dalam strukturisasi organisasi. Komunikasi yang menghasilkan pengalaman tersebut melahirkan pola-pola baru. Ada 4 (empat) pola komunikasi yang menjadi bahan acuan untuk mendeteksi setiap cara, motif dan hambatan dalam penulisan ini, yaitu: Pola Komunikasi PrimerPola Komunikasi SekunderPola Komunikasi LinearPola Komunikasi Sirkular Penelitian ini berpendapat bahwa dari keempat pola komunikasi yang di gunakan dalam proses penyelesaian maka dapat di deteksi pola komunikasi apa yang di terapkan suatu Perusahaan dalam mempertahankan citra, meskipun perlu pembuktian lebih lanjut. Pada aras lokal, terlihat pada studi kasus PT. Lion Air Indonesia cabang Manado bahwa dari setiap kasus yang terjadi di sepanjang tahun 2012 menghasilkan bertumbuhnya upaya perbaikan dan mekanisme yang telah di capai dan harus di capai Public Relation Officer PT. Lion Air Indonesia untuk menjawab setiap kebutuhan pengguna jasa penerbangan

Identifikasi Bakteri Aerob Pada Makanan Jajanan Jagung Bakar Di Pinggiran Jalan Ring Road Manado

: Corn is a food that is usually made in the form of roasted corn. Microbial contamination in food can through environmental pollution, behavior management of food, equipment processing, processing space and seasonings. Contaminated food can cause food poisoning. The purpose of this research is to determine the aerobic bacteria in roasted corn street food on the outskirts of the Ring Road Street Manado. This research used a prospective descriptive method. Samples taken are roasted corn, with a total sample of 20 samples and sampling method using random sampling method, then performed the isolation and identification of bacteria. The results of the research from 10 samples of roasted corn not smeared seasonings showed 1 sample no growth and 9 samples growth, i.e. Bacillus subtilis, Enterobacter agglomerans, Serratia rubidaea, Lactobacillus sp., Gram-negative coccus, and Enterobacter cloacae, then 10 samples of roasted corn smeared seasonings showed 1 sample no growth and 9 samples growth, i.e. Bacillus subtilis, Enterobacter agglomerans, Serratia rubidaea, Lactobacillus sp., Enterobacter cloacae, Streptococcus sp., and Pseudomonas sp. The conclusion of this research is the discovery of bacteria in roasted corn not smeared and smeared seasonings. This indicates that the processing is not hygienic

Increased incidence of colon cancer among individuals younger than 50 years : a 17 years analysis from the cancer registry of the municipality of Milan, Italy

Background: Colorectal cancer (CRC) overall incidence has been decreasing in the last decade. However, there is evidence of an increasing frequency of early-onset CRC in young individuals in several countries. The aim of this study is to evaluate the trends of CRC occurrence over 17 years in the municipality of Milan, Italy, focusing on early-onset CRC. Population and methods: This retrospective study was performed using the Cancer Registry of the municipality of Milan, including all cases of CRC diagnosed 1999-2015. Incidence rates were stratified by age and anatomic subsite, and trends over time were measured using the estimated annual percentage change. Age-period-cohort modelling was used to disentangle the different effects. Results: 18,783 cases of CRC were included. CRC incidence rates among individuals aged 50\u201360 years declined annually by 3% both in colon and in rectal cancer. Conversely, in adults younger than 50 years, overall CRC occurrence increased annually by 0.7%, with a diverging trend for colon (+2.6%) and rectal ( 125.3%) cancer. Among individuals aged 60 years and older, CRC incidence rates increased by 1.0% annually up to 2007, and decrease thereafter by 4% per year, both for colon and rectal cancer. Age-period-cohort models showed a reduction of CRC risk for the cohorts born up to 1979, followed by an increase in younger cohorts. In contrast, rectal cancer among women showed a systematic risk decrease for all birth cohorts. Conclusions: The study highlights increasing incidence of colon cancer in younger subjects and a decrease in incidence rates for rectal cancer in females

Influence of cranial radiotherapy on outcome in children with acute lymphoblastic leukemia treated with contemporary therapy

Purpose We sought to determine whether cranial radiotherapy (CRT) is necessary to prevent relapse in any subgroup of children with acute lymphoblastic leukemia (ALL). Patients and Methods We obtained aggregate data on relapse and survival outcomes for 16,623 patients age 1 to 18 years old with newly diagnosed ALL treated between 1996 and 2007 by 10 cooperative study groups from around the world. The proportion of patients eligible for prophylactic CRT varied from 0%to 33% by trial and was not related to the proportion eligible for allogeneic stem-cell transplantation in first complete remission. Using a random effects model, with CRT as a dichotomous covariate, we performed a single-arm metaanalysis to compare event-free survival and cumulative incidence of isolated or any CNS relapse and isolated bone marrow relapse in high-risk subgroups of patients who either did or did not receive CRT. Results Although there was significant heterogeneity in all outcome end points according to trial, CRT was associated with a reduced risk of relapse only in the small subgroup of patients with overt CNS disease at diagnosis, who had a significantly lower risk of isolated CNS relapse (4% with CRT v 17% without CRT; P = .02) and a trend toward lower risk of any CNS relapse (7% with CRT v 17% without CRT; P = .09). However, this group had a relatively high rate of events regardless of whether or not they received CRT (32% [95% CI, 26% to 39%] v 34% [95% CI, 19% to 54%]; P = .8). Conclusion CRT does not have an impact on the risk of relapse in children with ALL treated on contemporary protocols

Reporting of rehabilitation intervention for low back pain in randomized controlled trials : Is the treatment fully replicable?

Study Design. Methodological review of randomized controlled trials (RCTs). Objective. To assess the quality of reporting of rehabilitation interventions for mechanical low back pain (LBP) in published RCTs. Summary of Background Data. Reporting of interventions in RCTs often focused on the outcome value and failed to describe interventions adequately. Methods. We systematically searched for all RCTs in Cochrane systematic reviews on LBP published in the Cochrane Database of Systematic Reviews until December 2013. The description of rehabilitation interventions of each RCT was evaluated independently by 2 of the investigators, using an ad hoc checklist of 7 items. The primary outcome was the number of items reported in sufficient details to be replicable in a new RCT or in everyday practice. Results. We found 11 systematic reviews, including 220 eligible RCTs, on LBP. Of those, 185 RCTs were included. The median publication year was 1998 (I-III quartiles, 1990 to 2004). The most reported items were the characteristics of participants (91.3%; 95% confidence interval [CI], 87.3-95.4), the intervention providers (81.1%; 95% CI, 75.4-86.7), and the intervention schedule (69.7%; 95% CI, 63-76). Based on the description of the intervention, less than one fifth would be replicable clinically. The proportion of trials providing all essential information about the participants and interventions increased from 14% (n=7) in 1971 to 1980 to 20% (n=75) in 2001 to 2010. Conclusion. Despite the remarkable amount of energy spent producing RCTs in LBP rehabilitation, the majority of RCTs failed to report sufficient information that would allow the intervention to be replicated in clinical practice. Improving the quality of intervention description is urgently needed to better transfer research into rehabilitation practices

Polysulfates block SARS‐CoV‐2 uptake through electrostatic interactions

Here we report that negatively charged polysulfates can bind to the spike protein of SARS-CoV-2 via electrostatic interactions. Using a plaque reduction assay, we compare inhibition of SARS-CoV-2 by heparin, pentosan sulfate, linear polyglycerol sulfate (LPGS) and hyperbranched polyglycerol sulfate (HPGS). Highly sulfated LPGS is the optimal inhibitor, with a half-maximal inhibitory concentration (IC50) of 67 μg/mL (approx. 1.6 μM). This synthetic polysulfates exhibit more than 60-fold higher virus inhibitory activity than heparin (IC50: 4084 μg/mL), along with much lower anticoagulant activity. Furthermore, in molecular dynamics simulations, we verified that LPGS can bind stronger to the spike protein than heparin, and that LPGS can interact even more with the spike protein of the new N501Y and E484K variants. Our study demonstrates that the entry of SARS-CoV-2 into host cells can be blocked via electrostatic interaction, therefore LPGS can serve as a blueprint for the design of novel viral inhibitors of SARS-CoV-2

Men and Women Exhibit a Differential Bias for Processing Movement versus Objects

Sex differences in many spatial and verbal tasks appear to reflect an inherent low-level processing bias for movement in males and objects in females. We explored this potential movement/object bias in men and women using a computer task that measured targeting performance and/or color recognition. The targeting task showed a ball moving vertically towards a horizontal line. Before reaching the line, the ball disappeared behind a masking screen, requiring the participant to imagine the movement vector and identify the intersection point. For the color recognition task, the ball briefly changed color before disappearing beneath the mask and participants were required only to identify the color shade. Results showed that targeting accuracy for slow and fast moving balls was significantly better in males compared to females. No sex difference was observed for color shade recognition. We also studied a third, dual attention task comprised of the first two, where the moving ball briefly changed color randomly just before passing beneath the masking screen. When the ball changed color, participants were required only to identify the color shade. If the ball didn't change color, participants estimated the intersection point. Participants in this dual attention condition were first tested with the targeting and color tasks alone and showed results that were similar to the previous groups tested on a single task. However, under the dual attention condition, male accuracy in targeting, as well as color shade recognition, declined significantly compared to their performance when the tasks were tested alone. No significant changes were found in female performance. Finally, reaction times for targeting and color choices in both sexes correlated highly with ball speed, but not accuracy. Overall, these results provide evidence of a sex-related bias in processing objects versus movement, which may reflect sex differences in bottom up versus top-down analytical strategies