28 research outputs found

    THE IMPACT OF PERCEIVED VALUE ON CUSTOMER SATISFACTION TOWARDS SPA LOYALTY IN JAKARTA

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    THE IMPACT OF PERCEIVED VALUE ON CUSTOMER SATISFACTION TOWARDS SPA LOYALTY IN JAKARTA - Perceived Value, Customer satisfaction, Customer loyalty, Spa industry, Service industry, Recommendation, Repeat buying, Repurchase agreement

    ANALISIS PENGAKUAN PENDAPATAN JASA AERONAUTIKA BERDASARKAN PSAK NO. 23 TAHUN 2015 PADA PT ANGKASA PURA I (PERSERO) CABANG JUANDA SURABAYA

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    Berdasarkan hasil yang diperoleh selama kegiatan Praktik Kerja Lapangan (PKL) di PT Angkasa Pura I (Persero) Bandar Udara Juanda, maka dapat disimpulkan hal-hal sebagai berikut : 1. Dalam mengakui pendapatannya, PT Angkasa Pura I (Persero) Cabang Juanda menggunakan dasar yang telah sesuai dengan PSAK No. 23 Tahun 2015 yaitu pendapatan diakui hanya jika kemungkinan besar manfaat ekonomik sehubungan dengan transaksi tersebut akan mengalir ke entitas. 2. Prinsip pengakuan pendapatan aeronautika yang digunakan PT Angkasa Pura I (Persero) Cabang Juanda adalah prinsip direalisasi atau dapat direalisasi (realized or reazible), yaitu pendapatan diakui setelah jasa diserahkan sehingga menimbulkan penerimaan kas atau piutang. 3. Dalam pencatatan pendapatannya, PT Angkasa Pura I (Persero) Cabang Juanda menggunakan metode accrual basis, yaitu metode yang pencatatannya pada saat transaksi terjadi. Tujuannya agar dapat menggambarkan kondisi laporan keuangan yang sebenarnya, bukan hanya dari posisi kasnya saja. 4. Pengukuran pendapatan PT Angkasa Pura I (Persero) Cabang Juanda diukur dengan nilai wajar sesuai dengan tarif yang telah ditetapkan oleh pemerintah yang dikontrol oleh Direktorat Jenderal Perhubungan Udara. 5. Pencatatan dan penyajian atas pendapatan telah disajikan oleh PT Angkasa Pura I (Persero) Cabang Juanda secara jelas dan wajar dalam laporan keuangan perusahaan

    Phytochemistry and Ethnopharmacology of the Ecuadorian Flora. A Review.

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    Ecuador owns many high quantity and wealthy ecosystems that contain an elevated biodiversity in flora and fauna. The use of native medicinal plants has been maintained by at least 18 different indigenous cultures; furthermore, this country has been the witness of the discovery of important medicinal plants, such as Cinchona, and is an understudied resource of new natural products. The objective of this review is to update the ethnopharmacological and phytochemical studies accomplished on the Ecuadorian flora, pointing to the 253 native families and more than 15,000 species registered at present

    Genetic characterisation of Norovirus strains in outpatient children from rural communities of Vhembe district / South Africa, 2014-2015

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    Background: Norovirus (NoV) is now the 24 most common causes of both outbreaks and sporadic non-bacterial gastroenteritis worldwide. However, data supporting the role of NoV in diarrheal disease are limited in the African continent. Objectives: This study investigates the distribution of NoV genotypes circulating in outpatient children from rural communities of Vhembe district / South Africa. Study design: Stool specimens were collected from children under five years of age with diarrhea, and controls without diarrhea, between July 2014 and April 2015. NoV positive samples, detected previously by Realtime PCR, were analysed using conventional RT-PCR targeting the partial capsid and polymerase genes. Nucleotide sequencing methods were performed to genotype the strains. Results: The sequence analyses demonstrated multiple NoV genotypes including GI.4 (13.8%), GI.5 (6.9%), GII.14 (6.9%), GII.4 (31%), GII.6 (3.4%), GII.P15 (3.4%), GII.P21 (3.4%) and GII.Pe (31%). The most prevalent NoV genotypes were GII.4 Sydney 2012 variants (n=7) among the capsid genotypes, GII.Pe (n=9) among the polymerase genotypes and GII.Pe/GII.4 Sydney 2012 (n=8) putative recombinants among the RdRp/Capsid genotypes. Two unassigned GII.4 variants were found. Conclusions: The findings highlighted NoV genetic diversity and revealed continuous pandemic spread and predominance of GII.Pe/GII.4 Sydney 2012, indicative of increased NoV activity. An unusual RdRp genotype GII.P15 and two unassigned GII.4 variants were also identified from rural settings of the Vhembe district/South Africa. NoV surveillance is warranted to help to inform investigations into NoV evolution and disease burden, and to support on-going vaccine development programmes

    Development and characterization of polymeric nanoparticles itraconazole

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    Submitted by Marlene Santos ([email protected]) on 2014-12-16T19:58:48Z No. of bitstreams: 2 Dissertação - Percília de Andrade Lucena - 2014.pdf: 1506404 bytes, checksum: c895c029b3a1ac62acf42cd19fad7214 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Approved for entry into archive by Luciana Ferreira ([email protected]) on 2014-12-22T10:32:36Z (GMT) No. of bitstreams: 2 Dissertação - Percília de Andrade Lucena - 2014.pdf: 1506404 bytes, checksum: c895c029b3a1ac62acf42cd19fad7214 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5)Made available in DSpace on 2014-12-22T10:32:36Z (GMT). No. of bitstreams: 2 Dissertação - Percília de Andrade Lucena - 2014.pdf: 1506404 bytes, checksum: c895c029b3a1ac62acf42cd19fad7214 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2014-03-19Polymeric nanoparticles have been used as carriers of drugs that are able to increase the efficacy of many active ingredients. Among the nanocarriers include nanocapsules (NCs), which are vesicular structures containing oil inside surrounded by a polymer wall and nanospheres (NSs) that are impregnated with polymer matrices drug throughout its surface. These structures have many applications such as optimizing drug delivery and reducing the toxic potential of drugs. Itraconazole family of a drug Azole has a broad spectrum of action against fungi and has appropriate pharmacokinetic characteristics for a drug. Thus, this study aims to develope and characterize nanostructured systems containing Itraconazole. Polymeric nanoparticles were obtained by the nanoprecipitation technique, lyophilized, characterized, and evaluated physical-chemically incorporated into mucoadhesive topical formulation. Nanocapsules containing Itraconazole showed encapsulation efficiency rate of 99 ± 6.9%, a mean diameter of 190 ± 10.1 nm, PDI 0.1 ± 0:06 and zeta potential -15 ± 2.5 mV. The nanospheres exhibited rate of encapsulation efficiency of 97 ± 2.8%, mean diameter 120 ± 0.8 nm, 0.1 ± 0.01 PDI and zeta potential -10 ± 3.5 mV. Lyophilization was carried out with 10% trehalose + 10% sucrose, achieving satisfactory results. The drug release after 30 days at 37 °C was 99% for the NCs and 92% for the NEs. The mucoadhesive topical formulation has in its composition 60% Poloxamer 188, 20% polyethylene glycol 400 and 5mg nanostructured itraconazole were incorporated homogeneously. The results indicate that the formulation of Itraconazole in polymeric nanoparticles has potential for in vivo use in the topical treatment of fungal infections.Nanopartículas poliméricas têm sido utilizadas como carreadores de fármacos capazes de aumentar a eficácia de muitos insumos ativos. Dentre os nanocarreadores, destacam-se: nanocápsulas (NCs), que são estruturas vesiculares, contendo óleo no interior, circundadas por uma parede polimérica e nanoesferas (NEs) que são matrizes poliméricas impregnadas com fármaco por toda sua superfície. Essas estruturas possuem diversas aplicações como otimizar a entrega de fármacos e reduzir o potencial tóxico. O Itraconazol um fármaco da família dos azóis possui um amplo espectro de ação contra fungos e apresenta características farmacocinéticas apropriadas para um fármaco. Sendo assim, o presente trabalho tem como objetivo desenvolver e caracterizar sistemas nanoestruturados contendo Itraconazol. As nanopartículas poliméricas foram obtidas através da técnica da nanoprecipitação, liofilizadas, caracterizadas, avaliadas físicoquimicamente e incorporadas em formulação tópica mucoadesiva. As nanocápsulas contendo Itraconazol apresentaram taxa de eficiência de encapsulação de 99±6.9%, diâmetro médio de 190±10.1 nm, PDI 0.1±0.06 e potencial zeta -15±2.5 mV. As nanoesferas exibiram taxa de eficiência de encapsulação de 97±2.8%, diâmetro médio de 120±0.8 nm, PDI 0.1±0.01 e potencial zeta -10±3.5 mV. A liofilização foi realizada com 10% de trealose + 10% de sacarose, alcançando resultados satisfatórios. A liberação do fármaco após 30 dias a 37°C foi de 99% para as NCs e 92% para as NEs. A formulação tópica mucoadesiva possui em sua composição 60% Poloxamer 188 e 20% de Polietilenoglicol 400 e 5mg de itraconazol nanoestruturado foram incorporados homogeneamente. Os resultados indicam que a formulação de itraconazol em nanopartículas poliméricas apresenta potencial para utilização in vivo no tratamento tópico de infecções fúngicas

    PENGARUH RASIO KEUANGAN DAN RISK BASED CAPITAL TERHADAP KONDISI FINANCIAL DISTRESS PADA PERUSAHAAN ASURANSI KERUGIAN DI INDONESIA YANG TERDAFTAR DI OJK

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    Penelitian ini bertujuan untuk mengetahui pengaruh rasio beban klaim, rasio likuiditas, rasio pertumbuhan premi, Return On Asset (ROA), dan risk based capital terhadap kondisi financial distress yang dikategorikan berdasarkan laba bersih negatif atau ekuitas negatif perusahaan. Penelitian ini dilakukan pada perusahaan asuransi kerugian yang terdaftar di Otoritas Jasa Keuangan pada periode 2012 hingga 2016 dengan total 203 sampel yang diteliti. Metode statistik yang digunakan untuk menguji hipotesis dalam penelitian ini adalah regresi logistik pada tingkat signifikansi 5% (α=5%) dengan menggunakan metode enter. Hasil penelitian menunjukkan bahwa rasio beban klaim dan risk based capital tidak berpengaruh terhadap kondisi financial distress pada perusahaan asuransi kerugian. Sedangkan variabel yang dominan yang dapat digunakan untuk memprediksi secara signifikan kemungkinan terjadinya financial distress antara lain, rasio likuiditas dengan tingkat signifikan sebesar 0,001, rasio pertumbuhan premi dengan tingkat signifikan sebesar 0,002, dan ROA dengan tingkat signifikan sebesar 0,000

    The complete chloroplast genome of Hippeastrum rutilum

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    Biosynthesis and Characterization of Nanocellulose-Gelatin Films

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    A nanocellulose-gelatin (bacterial cellulose gelatin (BCG)) film was developed by a supplement of gelatin, at a concentration of 1%–10% w/v, in a coconut-water medium under the static cultivation of Acetobacter xylinum. The two polymers exhibited a certain degree of miscibility. The BCG film displayed dense and uniform homogeneous structures. The Fourier transform infrared spectroscopy (FTIR) results demonstrated interactions between the cellulose and gelatin. Incorporation of gelatin into a cellulose nanofiber network resulted in significantly improved optical transparency and water absorption capacity of the films. A significant drop in the mechanical strengths and a decrease in the porosity of the film were observed when the supplement of gelatin was more than 3% (w/v). The BCG films showed no cytotoxicity against Vero cells
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