Responsabilidade aduaneira no contrato “delivered ex-ships”

O presente estudo busca abordar a responsabilidade do exportador na modalidade contratual específica denominada “delivered ex ships”, assim intitulado de acordo com os “Incoterms”. O artigo procura esclarecer a natureza de tal modalidade contratual, bem como até onde se estende a responsabilidade do exportador quanto a danos ocorridos no produto exportado, definindo, ainda, a responsabilidade do transportador pelas avarias e a obrigação do exportador de efetuar o pagamento do imposto de exportação, analisando os aspectos material, pessoal e temporal do seu fato gerador e distinguindo esta das obrigações contratuais atinentes ao mero transportador

A FEMINIZAÇÃO DA VELHICE: UMA ABORDAGEM BIOPSICOSSOCIAL DO FENÔMENO

O envelhecimento populacional traz consigo uma série de desafios que exigem a atenção de todos, principalmente do Estado no que tange a implementação de políticas públicas. Diante disso, o presente estudo tem como objetivo levantar a temática da feminização da velhice, um fenômeno resultante da transição demográfica, no qual o número de mulheres com idade maior ou igual à 60 anos se sobressai ao contingente masculino. Trata-se de um ensaio teórico realizado através de levantamento bibliográfico traçando aspectos biopsicossocias que circundam a realidade das idosas. Evidencia-se que diante à feminização da velhice a variável gênero atua como fator determinante, tornando-se necessário estudos que voltem-se para tal realidade e busquem alternativas que possam solucionar desfechos negativos enfrentados pelas mulheres idosas

Caracterização de pacientes oncológicos sob a ótica da teoria de Wanda Aguiar / Characterization of oncologic patients from the perspective of Wanda Aguiar theory

Objetivo: Caracterizar os pacientes oncológicos sob a ótica da teoria de enfermagem de Wanda Aguiar Horta. Método: Trata-se de um estudo do tipo exploratório, pesquisa de campo, de corte transversal e de abordagem quantitativa, sendo realizado na cidade de Caruaru/PE, no Centro de Oncologia de Caruaru (CEOC), envolvendo 51 pacientes que estiverem em tratamento oncológico. O estudo foi submetido ao comitê de ética, respeitando a diretrizes e critérios estabelecidos na resolução 466/12 e a 510/16 do conselho nacional de saúde, sob o número do CAAE 16337319.0.0000.5666. Resultados: Mostra-se pelos resultados da análise, que a maioria 72% desses pacientes, eram do sexo feminino e quanto ao fator idade, a maioria dos pacientes 31% deles estavam acima dos 65 anos de idade. Conclusão: Frente ao exposto, observou-se que o câncer traz repercussões para a vida do indivíduo em tratamento oncológico e mesmo com o avanço tecnológico e métodos terapêuticos variados, que promovem a redução da taxa de mortalidade entre os pacientes acometidos por essa patologia, ainda se caracteriza como sendo uma doença dolorosa, como retratado por alguns pacientes quando questionados sobre a sua percepção dolorosa. Diante da análise transversal realizada das categorias, percebeu-se que os entrevistados consideraram que a doença afeta a sua autoestima e percepção corporal, ainda que alguns retratem serem otimistas, a doença afeta muito os pacientes quando aos aspectos biopsicossociai

Internações por transtornos neuróticos relacionados ao stress e sintomas somáticos no Brasil de 2019 a 2023: Uma abordagem sob a ótica da medicina integrativa

  According to the WHO, in 2019, 970 million people had mental disorders, with 15% of working-age adults experiencing psychosis. Brazil has the highest proportion of anxious people (9.3%). This work aims to identify and analyze the epidemiological profile of hospital morbidity due to neurotic disorders related to stress and somatic symptoms in Brazil. This study is ecological, quantitative and retrospective, using data from the SUS Hospital Morbidity Information System (SIH/SUS) from DATASUS. The variables considered were: region, type of service, age group, sex and color/race. Between 2019 and 2023, there were 15,354 hospitalizations for neurotic disorders related to stress and somatic symptoms in Brazil. Of these, 89.48% were emergencies. The majority of patients were between 20 and 29 years old (22.47%), 65.85% of whom were women. Regarding color/race, 39.18% were white, 35.63% mixed race and 18.24% without information.Segundo a OMS, em 2019, 970 milhões de pessoas tinham transtornos mentais, com 15% dos adultos em idade laboral enfrentando psicose. O Brasil tem a maior proporção de pessoas ansiosas (9,3%). Este trabalho objetiva identificar e analisar o perfil epidemiológico da morbidade hospitalar por transtornos neuróticos relacionados ao stress e sintomas somáticos no Brasil. Este estudo é ecológico, quantitativo e retrospectivo, usando dados do Sistema de Informação sobre Morbidade Hospitalar do SUS (SIH/SUS) do DATASUS. As variáveis consideradas foram: região, tipo de atendimento, faixa etária, sexo e cor/raça. Entre 2019 e 2023, houve 15.354 internações por transtornos neuróticos relacionados ao stress e sintomas somáticos no Brasil. Destas, 89,48% foram urgências. A maioria dos pacientes tinha entre 20 e 29 anos (22,47%), sendo 65,85% mulheres. Quanto à cor/raça, 39,18% eram brancos, 35,63% pardos e 18,24% sem informação

Responsabilidade aduaneira no contrato “delivered ex-ships”

O presente estudo busca abordar a responsabilidade do exportador na modalidade contratual específica denominada “delivered ex ships”, assim intitulado de acordo com os “Incoterms”. O artigo procura esclarecer a natureza de tal modalidade contratual, bem como até onde se estende a responsabilidade do exportador quanto a danos ocorridos no produto exportado, definindo, ainda, a responsabilidade do transportador pelas avarias e a obrigação do exportador de efetuar o pagamento do imposto de exportação, analisando os aspectos material, pessoal e temporal do seu fato gerador e distinguindo esta das obrigações contratuais atinentes ao mero transportador

Molecular genotyping of G6PD mutations and Duffy blood group in Afro-descendant communities from Brazilian Amazon

Abstract Glucose-6-phosphate dehydrogenase deficiency (G6PDd) and Duffy-negative blood group are two red blood cells variants that confer protection against malaria. In this study, the distribution of the most common G6PD variants (G6PD*A-, GGPD*A and G6PD Mediterranean) and the major alleles of the Duffy blood group (FY*A, FY*B and FY*BES) were investigated in an Afro-descendant population from state of Pará, Brazilian Amazon. G6PD variants and Duffy blood group alleles were determined by TaqMan SNP genotyping assay. Overall, molecular genotyping revealed the presence of G6PD variants in 126 (24%) of the individuals studied (5% male and 19% female), and frequencies of the G6PD*A- and G6PD*A alleles were 0.061 and 0.104, respectively. Duffy blood group genotyping showed that 24.3% of people were Duffy-negative and 41.3% were heterozygous for FY*BES. The frequency of allele FY*BES was 41.0%. The results emphasize the need to monitor G6PD deficiency for the use of primaquine in the routine care of the Afro-descendant communities of the Trombetas, Erepecuru and Cumná rivers, evaluating the risks of hemolytic crisis in case of recurrence of malaria in the region. In addition, the possible greater protection against malaria conferred by these erythrocyte polymorphisms deserves to be better investigated and explored among these Afro-descendants

Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life

International audienceBackground and aim: Maternal dyslipidemia is recognized as a risk factor for the development of arterial hypertension (AH) and cardiovascular dysfunction in offspring. Here we evaluated the effects of probiotic administration of a specific strain of Lactiplantibacillus plantarum(WJL) during pregnancy and lactation on gut microbiota and metabolic profile in dams fed with a high-fat and high-cholesterol (HFHC) diet and its long-term effects on the cardiovascular function in male rat offspring.Methods and results: Pregnant Wistar rats were allocated into three groups: dams fed a control diet (CTL = 5), dams fed a HFHC diet (DLP = 5) and dams fed a HFHC diet and receivingL. plantarum WJL during pregnancy and lactation (DLP-Lp(WJL)).L. plantarum WJL (1 x 10(9)CFU) or vehicle (NaCl, 0.9%) was administered daily by oral gavage for 6 weeks, covering the pregnancy and lactation periods. After weaning, male offspring received a standard diet up to 90 days of life. Biochemical measurements and gut microbiota were evaluated in dams. In male offspring, blood pressure (BP), heart rate (HR) and vascular reactivity were evaluated at 90 days of age. Dams fed with a HFHC diet during pregnancy and lactation had increased lipid profile and insulin resistance and showed dysbiotic gut microbiota. Administration of L. plantarum WJL to dams having maternal dyslipidemia improved gut microbiota composition, lipid profile and insulin resistance in them. Blood pressure was augmented and vascular reactivity was impaired with a higher contractile response and a lower response to endothelium-dependent vasorelaxation in DLP male offspring. In contrast, male offspring of DLP-Lp(WJL) dams had reduced blood pressure and recovered vascular function in later life.Conclusion: Administration ofL. plantarum WJL during pregnancy and lactation in dams improved gut microbiota diversity, reduced maternal dyslipidemia and prevented cardiovascular dysfunction in male rat offspring

Effect of Early Mobilization on Respiratory and Limb Muscle Strength and Functionality of Nonintubated Patients in Critical Care: A Feasibility Trial

Purpose. To assess the potential effectiveness or efficacy of early mobilization on respiratory and peripheral muscle strengths and functionality in nonintubated patients. Methods. For 40 nonintubated patients over 18 years of age with over 24-hour intensive care unit (ICU) stay allocated to a single intervention, an incremental mobilization protocol was initiated. Maximal inspiratory and expiratory pressures (MIP and MEP), peripheral muscle strength (handgrip strength (HGS) and Medical Research Council scale (MRC-s)), and functionality (FIM, ICF-BMS, PFIT-s, and FSS-ICU scales) were evaluated at ICU admission and discharge. Results. All outcomes were significantly improved (pre vs. post values): MIP (43.93 ± 21.95 vs. 54.12 ± 21.68 cmH2O; P<0.001), MEP (50.32 ± 28.65 vs. 60.30 ± 21.23; P=0.002), HGS (25.5 (9.58) vs. 27.5 (9.48); P=0.046), MRC-s (58.52 ± 2.84 vs. 59.47 ± 1.81; P=0.023), FIM (54.4 ± 22.79 vs. 69.48 ± 12.74), ICF-BMS (28.63 ± 16.19 vs. 14.03 ± 11.15), PFIT-s (9.55 ± 2.34 vs. 11.18 ± 1.32) (P<0.001), and FSS-ICU (28.7 ± 9.1 vs. 32.6 ± 5.0; P=0.001). The ceiling effect at admission/discharge was in MRC-s (60/82.5%), FSS-ICU (50/70%), and FIM (35/62.5%). The floor effect occurred at discharge in ICF-BMS (7.5/52.5%). Conclusions. The early mobilization protocol seemed effective at maintaining/increasing the respiratory muscle strength and functionality of nonintubated patients in critical care. Ceiling effect was high for MRC-s, FSS-ICU, and FIM scales

Metagenomic insights into the plasma virome of Brazilian patients with prostate cancer

Growing evidence suggests that metavirome changes could be associated increased risk for malignant cell transformation. Considering Viruses have been proposed as factors for prostate cancer induction. The objective of this study was to examine the composition of the plasma metavirome of patients with prostate cancer. Blood samples were obtained from 49 male patients with primary prostate adenocarcinoma. Thirty blood donors were included as a control group. The obtained next-generation sequencing data were analyzed using a bioinformatic pipeline for virus metagenomics. Viral reads with higher abundance were assembled in contigs and analyzed taxonomically. Viral agents of interest were also confirmed by qPCR. Anelloviruses and the Human Pegivirus-1 (HPgV-1) were the most abundant component of plasma metavirome. Clinically important viruses like hepatitis C virus (HCV), cytomegalovirus and human adenovirus type C were also identified. In comparison, the blood donor virome was exclusively composed of torque teno virus types (TTV) types. The performed HPgV-1 and HCV phylogeny revealed that these viruses belong to commonly detected in Brazil genotypes. Our study sheds light on the plasma viral abundance in patients with prostatic cancer. The obtained viral diversity allowed us to separate the patients and controls, probably suggesting that malignant processes may influence virome composition. More complex and multiple approach investigations are necessary to examine the likely causal relationship between metavirome and its nvolvement in prostate cancer