On Holy Boughs and Sacred Fools: Virginia Woolf Under the Shadow of Jane Harrison

Insofar as the influence of myths and ritualistic practices on Modernist artists becomes evident, this paper explores the still underestimated degree of convergence between Harrison.’s theories, as a direct inheritor of Frazer.’s major postulates, and some of Virginia Woolf.’s fictional works. Indeed, whereas some descriptive outlines of such connection have been carried out, the present analysis aims to reach further by examining the narrator.’s particular form of appropriation .—occasionally through sheer mockery and subversion.— of such traditions, which will undoubtedly shed light on Woolf.’s actual apprehension of the society of her time. En tanto que la influencia de los mitos y prácticas de índole ritual en los artistas del Modernismo resulta innegable, el presente artículo explora el aún infravalorado grado de convergencia entre las teorías de Jane Harrison, directa heredera de los postulados de Frazer, y algunas de las principales obras narrativas de Virginia Woolf. En efecto, mientras que se han llevado a cabo algunos estudios descriptivos, este artículo pretende ir más allá a través del análisis de la particular forma de adopción de dichas tradiciones por parte de la narradora .– incluyendo la patente mofa y subversión de dichas tradiciones, lo que, sin duda, contribuirá a arrojar luz sobre la auténtica noción de Woolf con respecto a la sociedad de su tiempo

La percepción de las personas sordas sobre la lectura: una mirada a la adolescencia

El presente estudio pone el acento en la percepción que las personas sordas tienen sobre la lectura, con una especial reflexión sobre la adolescencia. Describe cuáles son los hábitos de lectura de la población adolescente sorda, sus itinerarios y estilos lectores, marcados en muchas ocasiones por las dificultades a las que se enfrentan, pero también por una férrea voluntad de superar las barreras que les separan de la experiencia lectora

La percepción de las personas sordas sobre la lectura: una mirada a la adolescencia

El presente estudio pone el acento en la percepción que las personas sordas tienen sobre la lectura, con una especial reflexión sobre la adolescencia. Describe cuáles son los hábitos de lectura de la población adolescente sorda, sus itinerarios y estilos lectores, marcados en muchas ocasiones por las dificultades a las que se enfrentan, pero también por una férrea voluntad de superar las barreras que les separan de la experiencia lectora

Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER); Agencia Española del Medicamento; Consejería de Salud de Andalucía.Background & Aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into the Spanish DILI Registry over a 20-year time period. Methods: Cases were identified, diagnosed and followed prospectively. Clinical features, drug information and outcome data were collected. Results: A total of 843 patients, with a mean age of 54 years (48% females), were enrolled up to 2018. Hepatocellular injury was associated with younger age (adjusted odds ratio [aOR] per year 0.983; 95% CI 0.974-0.991) and lower platelet count (aOR per unit 0.996; 95% CI 0.994-0.998). Anti-infectives were the most common causative drug class (40%). Liver-related mortality was more frequent in patients with hepatocellular damage aged ≥65 years (p = 0.0083) and in patients with underlying liver disease (p = 0.0221). Independent predictors of liver-related death/transplantation included nR-based hepatocellular injury, female sex, higher onset aspartate aminotransferase (AST) and bilirubin values. nR-based hepatocellular injury was not associated with 6-month overall mortality, for which comorbidity burden played a more important role. The prognostic capacity of Hy's law varied between causative agents. Empirical therapy (corticosteroids, ursodeoxycholic acid and MARS) was prescribed to 20% of patients. Drug-induced autoimmune hepatitis patients (26 cases) were mainly females (62%) with hepatocellular damage (92%), who more frequently received immunosuppressive therapy (58%). Conclusions: AST elevation at onset is a strong predictor of poor outcome and should be routinely assessed in DILI evaluation. Mortality is higher in older patients with hepatocellular damage and patients with underlying hepatic conditions. The Spanish DILI Registry is a valuable tool in the identification of causative drugs, clinical signatures and prognostic risk factors in DILI and can aid physicians in DILI characterisation and management. Lay summary: Clinical information on drug-induced liver injury (DILI) collected from enrolled patients in the Spanish DILI Registry can guide physicians in the decision-making process. We have found that older patients with hepatocellular type liver injury and patients with additional liver conditions are at a higher risk of mortality. The type of liver injury, patient sex and analytical values of aspartate aminotransferase and total bilirubin can also help predict clinical outcomes