Antitruste:: Uma Necessária Revisão Histórica

This article is a brief revisionist study about the history of Antitrust Law, in which we try to demonstrate that, in opposition to what the academic mainstream affirms, the antitrust statutes have not been edited to enforce free competition and/or to maximize the consumer welfare, but to protect inefficient firms who could not survive in a genuine free market, where competition was intense and produced extremely beneficial outcomes for the consumers: constant innovation, increase of production, better products/services and lower prices.Este artigo é um breve estudo revisionista da história do direito antitruste, no qual tentamos demonstrar que, ao contrário do que afirma o mainstream acadêmico, as leis antitruste não foram editadas para garantir a livre concorrência e/ou maximizar o bem-estar do consumidor, mas para proteger empresários ineficientes que não conseguiam se manter num ambiente de livre mercado genuíno, em que a competição era intensa e produzia resultados extremamente benéficos para os consumidores: inovação constante, aumento da produção, melhoria dos produtos/serviços e redução dos preços

Isolated right ventricular infarction: a diagnostic challenge

A 73-year-old woman was admitted to the emergency room due to sudden-onset dyspnoea, altered mental status and haemodynamic instability. ECG showed a junctional rhythm, T-wave inversion in I, aVL and V2-V6 (present in a previous ECG), and no ST/T changes in the right precordial leads. Transthoracic echocardiography, however, revealed a severe depression of global systolic function of right ventricle with akinesia of free wall and a normal left ventricular function. Coronary angiography showed an occlusion of the proximal segment of the right coronary artery, which was treated with balloon angioplasty, and a chronic lesion of the anterior descending artery. The patient had a good recovery and was discharged on the 14th day. Myocardial perfusion scintigraphy (stress and rest) was performed a month later, showing a fixed perfusion defect in the apex and anterior wall (medium-apical), with no signs of ischaemia.(undefined)info:eu-repo/semantics/publishedVersio

El derecho al descanso vacacional como mecanismo para conciliar la vida familiar y laboral: análisis del decreto legislativo N°713 y su modificatoria por el decreto legislativo N°1405

La presente tesis aborda el contenido esencial del derecho al descanso vacacional anual el cual se encuentra regulado dentro de nuestro ordenamiento jurídico peruano en el Decreto Legislativo N°713, así también, se realiza un análisis crítico de la reciente modificación de la mencionada norma, por el Decreto Legislativo N°1405, mediante el cual, busca usar la figura del fraccionamiento vacacional para conciliar la vida familiar y laboral, posibilitándole al trabajador, previo acuerdo con el empleador, fraccionar sus vacaciones hasta por periodos de un día, a fin de atender asuntos familiares. Tras un estudio detallado de los criterios establecidos por la Organización Internacional del Trabajo, mediante sus Convenios, recomendaciones e informes, y con argumentos propios de la doctrina del derecho laboral, podremos apreciar que en realidad el uso indiscriminado de la figura del fraccionamiento representa un desconocimiento de la naturaleza y finalidad del derecho al descanso vacacional anual y, por el contrario, no cumple con la finalidad de conciliar la vida familiar y laboral ya que reduce la posibilidad del trabajador a gozar de manera ininterrumpida el descanso vacacional, tiempo que, podría dedicárselo entre otros ámbitos, a la familia

Avanços do sistema de justiça: os 5 anos de vigência do novo Código de processo civil

- Divulgação dos SUMÁRIOS das obras recentemente incorporadas ao acervo da Biblioteca Ministro Oscar Saraiva do STJ. Em respeito à Lei de Direitos Autorais, não disponibilizamos a obra na íntegra.- Localização na estante: 347.91/.95(81) A946s- Coordenado por: Felipe Santa Cruz, Luiz Fux e André Godinho

A case report of papular-purpuric gloves and socks syndrome: A manifestation of the parvovirus B19

Introduction: The majority of parvovirus B19 infections are asymptomatic. In childhood, however, they may present as the fifth disease and in adults their manifestations can vary from mild, non-specific, cold-like symptoms to other forms of presentations. Papular-purpuric gloves and socks syndrome (PPGSS) is an uncommon form of parvovirus B19 infection, characterized by symmetric, pruriginous and painful erythema and edema of feet and hands. Generally, systemic symptoms are usually mild and dissemination to other body regions occurs in only 50% of the cases. The rash gradually progresses to petechiae and purpura delineating well demarcated "socks" and "gloves" on both feet and hands. The diagnosis is predominantly based on the clinical features. Serologic conversion is not considered as evidence of parvovirus B19 infection and histopathological findings from lesional skin are not specific. There are no definite antiviral drugs or vaccines against parvovirus. Patients with PPGSS require only symptomatic therapy. Case Report: We report the case of a 30-year-old female with this characteristic erythema caused by the parvovirus B19. Nevertheless, this case is remarkable because the patient had significant systemic manifestations and an exuberant perineal and oropharyngeal involvement. Further, the erythema assumed a bullous expression that has not been so commonly reported. A biopsy was performed which was unspecific and the diagnosis was confirmed with the serology and molecular detection of the virus in blood sample as well as on mouth swab. Our patient needed treatment to control pain and pruritus, fever was self-limited. Conclusion: A high index of suspicion is essential to diagnose patients with this syndrome. Early recognition can prevent unproductive measures and the good management of this infection.info:eu-repo/semantics/publishedVersio

In vitro evaluation of alkaline lignins as antiparasitic agents and their use as an excipient in the release of benznidazole

Copyright © 2023. Published by Elsevier B.V.The Amazon rainforest is considered the largest tropical timber reserve in the world. The management of native forests in the Amazon is one of the most sensitive geopolitical issues today, given its national and international dimension. In this work, we obtained and characterized physicochemical lignins extracted from branches and leaves of Protium puncticulatum and Scleronema micranthum. In addition, we evaluated in vitro its potential as an antioxidant, cytotoxic agent against animal cells and antiparasitic against promastigotes of Leishmania amazonensis, trypomastigotes of T. cruzi and against Plasmodium falciparum parasites sensitive and resistant to chloroquine. The results showed that the lignins obtained are of the GSH type and have higher levels of guaiacyl units. However, they show structural differences as shown by spectroscopic analysis and radar charts. As for biological activities, they showed antioxidant potential and low cytotoxicity against animal cells. Antileishmanial/trypanocidal assays have shown that lignins can inhibit the growth of promastigotes and trypomastigotes in vitro. The lignins in this study showed low anti-Plasmodium falciparum activity against susceptible strains of Plasmodium falciparum and were able to inhibit the growth of the chloroquine-resistant strain. And were not able to inhibit the growth of Schistosoma mansoni parasites. Finally, lignins proved to be promising excipients in the release of benznidazole. These findings show the potential of these lignins not yet studied to promote different biological activities.publishersversionpublishe

Trazado y diseño de tuberías de polipropileno en lugar de tuberías de PVC

El polipropileno es un material con características únicas, ya que su composición hace que sea un plástico muy resistente y que sus aplicaciones sean muy diversas. El sistema de tuberías de polipropileno viene siendo usado desde 2008 y ha revolucionado las bases de la fontanería por lo que es utilizado actualmente en un 60% de las obras de construcción. En este caso se evaluará los beneficios de las tuberías de polipropileno en comparación a las tuberías de PVC mediante un análisis comparativo entre el trazado y diseño para ambos sistemas. Por un lado, se contrastará las condiciones del trazado y diseño de los dos sistemas de tuberías. Por otro lado, se comprará cálculo de pérdidas de presión que se generan en ambos sistemas. La metodología se ampara en los pilares de una investigación cuantitativa. Se realizará el trazado y diseño utilizando las consideraciones para cada tipo de tuberías en el caso del pabellón de aulas de informática de un colegio en el distrito de La Molina. Los resultados que se obtuvieron muestran que existe un beneficio de utilizar menores accesorios con las tuberías de `polipropileno, sin embargo, en el este dato no ha influido en el cálculo de caída de presión, ya que sí se considera el coeficiente de rugosidad. Por otra parte, las dimensiones de los diámetros con polipropileno en este sistema fueron mayores que el de PVC, ya que se utiliza unidades de medida como es el métrico. Por lo tanto, se concluye que las condiciones de trazado y dimensionamiento con polipropileno generan mayores facilidades maximizando recursos en comparación de las tuberías de PVC. Asimismo, se presentaron algunas recomendaciones para trabajos futuros para profundizar el tema de la investigación.Trabajo de investigació

Com o diabo no corpo: os terríveis papagaios do Brasil colônia

Desde a Antiguidade, papagaios, periquitos e afins (Psittacidae) fascinaram os europeus por seu vivo colorido e uma notável capacidade de interação com seres humanos. A descoberta do Novo Mundo nada faria além de acrescentar novos elementos ao tráfico de animais exóticos há muito estabelecido pelos europeus com a África e o Oriente. Sem possuir grandes mamíferos, a América tropical participaria desse comércio com o que tinha de mais atrativo, essencialmente felinos, primatas e aves - em particular os papagaios, os quais eram embarcados em bom número. Contudo, a julgar pelos documentos do Brasil colônia, esses voláteis podiam inspirar muito pouca simpatia, pois nenhum outro animal - exceto as formigas - foi tantas vezes mencionado como praga para a agricultura. Além disso, alguns psitácidas mostravam-se tão loquazes que inspiravam a séria desconfiança de serem animais demoníacos ou possessos, pois só três classes de entidades - anjos, homens e demônios - possuíam o dom da palavra. Nos dias de hoje, vários representantes dos Psittacidae ainda constituem uma ameaça para a agricultura, enquanto os indivíduos muito faladores continuam despertando a suspeita de estarem possuídos pelo demônio. Transcendendo a mera curiosidade, essa crença exemplifica o quão intrincadas podem ser as relações do homem com o chamado “mundo natural”, revelando um universo mais amplo e multifacetado do que se poderia supor a princípio. Nesse sentido, a existência de aves capazes de falar torna essa relação ainda mais complexa e evidencia que as dificuldades de estabelecer o limite entre o animal e o humano se estendem além dos primatas e envolvem as mais inusitadas espécies zoológicas.Since ancient times, parrots and their allies (Psittacidae) have fascinated Europeans by their striking colors and notable ability to interact with human beings. The discovery of the New World added new species to the international exotic animal trade, which for many centuries had brought beasts to Europe from Africa and the Orient. Lacking large mammals, tropical America participated in this trade with its most appealing species, essentially felines, primates and birds - especially parrots - which were shipped in large numbers. It should be noted, however, that at times these birds were not well liked. In fact, according to documents from colonial Brazil, only the ants rank higher than parrots as the animals most often mentioned as agricultural pests. On the other hand, some of these birds were so chatty that people suspected them to be demonic or possessed animals, since only three classes of beings - angels, men and demons - have the ability to speak. Nowadays, several Psittacidae still constitute a threat to agriculture, and the suspicion that extremely talkative birds were demon possessed has also survived. More than a joke or a mere curiosity, this belief exemplifies how intricate man’s relationships with the “natural world” may be. In this sense, the existence of birds that are able to speak adds a further twist to these relationships, demonstrating that the problem of establishing a boundary between the animal and the human does not only involve primates, but also includes some unusual zoological species

O direito de empresa no Código Civil: comentários ao livro II (arts. 966 a 1.195)

Divulgação dos SUMÁRIOS das obras recentemente incorporadas ao acervo da Biblioteca Ministro Oscar Saraiva do STJ. Em respeito à lei de Direitos Autorais, não disponibilizamos a obra na íntegra. 347.7(81)(094.4) R175d STJ0008986