The Relationship between the Employees\u27 Perception of Effectiveness of Direct Manager and Overall Employee Satisfaction in a Community Hospital

The objective of this study was to determine the relationship between the employees’ perception of the effectiveness of their manager and overall employee satisfaction in a community hospital. The data was from nine employee satisfaction surveys conducted by the study organization from 2002 to 2010. Effectiveness of manager was a seven question section of the survey and overall satisfaction was a four question section. The effectiveness of manager questions were based on six leadership principles that the organization used in training the managers. The study tested the relationship between effectiveness of manager and satisfaction and the increase in effectiveness and satisfaction over the nine years. The findings showed a significant positive relationship between effectiveness of manager and employee satisfaction. The findings also show that effectiveness and satisfaction increased at a statistically significant level from year one to year nine

The role of data & program code archives in the future of economic research

This essay examines the role of data and program-code archives in making economic research "replicable." Replication of published results is recognized as an essential part of the scientific method. Yet, historically, both the "demand for" and "supply of" replicable results in economics has been minimal. "Respect for the scientific method" is not sufficient to motivate either economists or editors of professional journals to ensure the replicability of published results. We enumerate the costs and benefits of mandatory data and code archives, and argue that the benefits far exceed the costs. Progress has been made since the gloomy assessment of Dewald, Thursby and Anderson some twenty years ago in the American Economic Review, but much remains to be done before empirical economics ceases to be a "dismal science" when judged by the replicability of its published results.Econometrics ; Research

A study on vortex flow control on inlet distortion in the re-engined 727-100 center inlet duct using computational fluid dynamics

Computational fluid dynamics was used to investigate the management of inlet distortion by the introduction of discrete vorticity sources at selected locations in the inlet for the purpose of controlling secondary flow. These sources of vorticity were introduced by means of vortex generators. A series of design observations were made concerning the importance of various vortex generator design parameters in minimizing engine face circumferential distortion. The study showed that vortex strength, generator scale, and secondary flow field structure have a complicated and interrelated influence on the engine face distortion, over and above the initial geometry and arrangement of the generators. The installed vortex generator performance was found to be a function of three categories of variables: the inflow conditions, the aerodynamic characteristics associated with the inlet duct, and the design parameters related to the geometry, arrangement, and placement of the vortex generators within the outlet duct itself

The Geostationary Operational Satellite R Series SpaceWire Based Data System Architecture

The GOES-R program selected SpaceWire as the best solution to satisfy the desire for simple and flexible instrument to spacecraft command and telemetry communications. Data generated by GOES-R instruments is critical for meteorological forecasting, public safety, space weather, and other key applications. In addition, GOES-R instrument data is provided to ground stations on a 24/7 basis. GOES-R requires data errors be detected and corrected from origin to final destination. This paper describes GOES-R developed strategy to satisfy this requiremen

Observations of Binary Stars with the Differential Speckle Survey Instrument. II. Hipparcos Stars Observed in 2010 January and June

The results of 497 speckle observations of Hipparcos stars and selected other targets are presented. Of these, 367 were resolved into components and 130 were unresolved. The data were obtained using the Differential Speckle Survey Instrument at the WIYN 3.5 m Telescope. (The WIYN Observatory is a joint facility of the University of Wisconsin-Madison, Indiana University, Yale University, and the National Optical Astronomy Observatories.) Since the first paper in this series, the instrument has been upgraded so that it now uses two electron-multiplying CCD cameras. The measurement precision obtained when comparing to ephemeris positions of binaries with very well known orbits is approximately 1-2 mas in separation and better than 0°.6 in position angle. Differential photometry is found to be in very good agreement with Hipparcos measures in cases where the comparison is most relevant. We derive preliminary orbits for two systems

Semiclassical Gravity in the Far Field Limit of Stars, Black Holes, and Wormholes

Semiclassical gravity is investigated in a large class of asymptotically flat, static, spherically symmetric spacetimes including those containing static stars, black holes, and wormholes. Specifically the stress-energy tensors of massless free spin 0 and spin 1/2 fields are computed to leading order in the asymptotic regions of these spacetimes. This is done for spin 0 fields in Schwarzschild spacetime using a WKB approximation. It is done numerically for the spin 1/2 field in Schwarzschild, extreme Reissner-Nordstrom, and various wormhole spacetimes. And it is done by finding analytic solutions to the leading order mode equations in a large class of asymptotically flat static spherically symmetric spacetimes. Agreement is shown between these various computational methods. It is found that for all of the spacetimes considered, the energy density and pressure in the asymptotic region are proportional to 1/r^5 to leading order. Furthermore, for the spin 1/2 field and the conformally coupled scalar field, the stress-energy tensor depends only on the leading order geometry in the far field limit. This is also true for the minimally coupled scalar field for spacetimes containing either a static star or a black hole, but not for spacetimes containing a wormhole.Comment: 43 pages, 2 figures. Reference added, minor changes, PRD versio

Lucio Parenzan: an appreciation

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p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels.

BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is a common genetic disease with few treatment options other than renal replacement therapy. p21, a cyclin kinase inhibitor which has pleiotropic effects on the cell cycle, in many cases acts to suppress cell cycle progression and to prevent apoptosis. Because defects in cell cycle arrest and apoptosis of renal tubular epithelial cells occur in PKD, and in light of earlier reports that polycystin-1 upregulates p21 and that the cyclin-dependent kinase inhibitor roscovitine arrests progression in a mouse model, we asked whether (1) p21 deficiency might underlie ADPKD and (2) the mechanism of the salutary roscovitine effect on PKD involves p21.Methodsp21 levels in human and animal tissue samples as well as cell lines were examined by immunoblotting and/or immunohistochemisty. Apoptosis was assessed by PARP cleavage. p21 expression was attenuated in a renal tubular epithelial cell line by antisense methods, and proliferation in response to p21 attenuation and to roscovitine was assessed by the MTT assay.ResultsWe show that p21 is decreased in human as well as a non-transgenic rat model of ADPKD. In addition, hepatocyte growth factor, which induces transition from a cystic to a tubular phenotype, increases p21 levels. Furthermore, attenuation of p21 results in augmentation of cell cycle transit in vitro. Thus, levels of p21 are inversely correlated with renal tubular epithelial cell proliferation. Roscovitine, which has been shown to arrest progression in a murine model of PKD, increases p21 levels and decreases renal tubular epithelial cell proliferation, with no affect on apoptosis.ConclusionThe novelty of our study is the demonstration in vivo in humans and rat models of a decrement of p21 in cystic kidneys as compared to non-cystic kidneys. Validation of a potential pathogenetic model of increased cyst formation due to enhanced epithelial proliferation and apoptosis mediated by p21 suggests a mechanism for the salutary effect of roscovitine in ADPKD and supports further investigation of p21 as a target for future therapy