Balancing Structure and Learning in an Open Prison

Leira Prison is a branch of Trondheim Prison, functioning as a relatively small,open prison with a maximum capacity of only 29 inmates. Leira Prison appliesthe method ‘consequence pedagogy.’ This article aims to pinpoint howconsequence pedagogy is executed at Leira. 50% of the Leira inmates arereleased back into society, while new ones enter the prison. It is thereforeinteresting to see how they balance structure and at the same time adjust tochanges, enabling Leira Prison to continue as a learning organization. This articleidentifies three items, consequence pedagogy and the view of humans,maintenance of the philosophy and coherence in the community, and selfregulationof justice through interaction. The use of consequence pedagogyis deeply aligned to their positive view of humans and has generated a constructiveorganization based on empowerment and involvement of both staffand inmates. Consequently, management, staff and inmates maintain thephilosophy of consequence pedagogy through interaction and self-regulation.However, questions regarding the fundamentals of the consequence pedagogyare not raised

E-cycling and health benefits: A systematic literature review with meta-analyses

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Qualitative and Quantitative Comparison of Liquid–Liquid Phase Extraction Using Ethyl Acetate and Liquid–Solid Phase Extraction Using Poly-Benzyl-Resin for Natural Products

A key step in the process of isolating microbial natural products is the preparation of an extract from a culture. This step determines which molecules will be available for detection in the subsequent chemical and biological analysis of a biodiscovery pipeline. In the present study we wanted to document potential differences in performance between liquid–liquid extraction using ethyl acetate and liquid–solid extraction using a poly‐benzyl‐resin. For the comparison of the two extraction protocols, we spiked a culture of Flavobacterium sp. with a diverse selection of natural products of microbial and plant origin to investigate whether the methods were comparable with respect to selectivity. We also investigated the efficiency of the two extraction methods quantita‐ tively, using water spiked with a selection of natural products, and studied the quantitative effect of different pH levels of the aqueous solutions on the extraction yields of the two methods. The same compounds were extracted by the two methods, but the solid‐phase extract contained more media components compared with the liquid‐phase extract. Quantitatively, the two extraction methods varied in their recovery rates. We conclude that practical aspects could be more important when selecting one of the extraction protocols, as their efficiencies in extracting specific compounds were quite similar

Sykepleierens samhandling med foreldre i etableringen av en tillitsfull relasjon til barn som er innlagt på sykehus.

Bakgrunn Barn er sårbare og komplekse pasienter som hvert år utgjør en stor andel av alle innleggelser på sykehus. Tillit mellom sykepleier og det syke barnet kan bidra til å optimalisere, individualisere og kvalitetssikre helsehjelpen etter barnets behov og beste. Det er på bakgrunn av dette et særlig behov for kompetanseheving og satsing på forskning på hvordan sykepleieren bør samhandle med foreldre for å etablere tillit til barn. Hensikt Hensikten med oppgaven var å belyse betydningen av sykepleierens samhandling med foreldre i etableringen av en tillitsfull relasjon til barn som var innlagt på sykehus. Metode Vår integrative litteraturoversikt tok utgangspunkt i analysering av tre kvalitative-, og to kvantitative studier. Metoden som ble benyttet var Fribergs analysemodell, hvor vi gjennom sortering av enkeltdata sammenfattet til en ny helhet. Resultatene fra studiene og relevant teori utgjorde grunnlaget for oppgaven. Resultater Resultatene konstaterte at tillit var av betydningsfull verdi i behandlingen av barn innlagt på sykehus. Sykepleieren har i samsvar med yrkesetiske retningslinjer et ansvar i å etablere en relasjon basert på tillit til barnet som pasient, og resultatene viste at samhandling med foreldre var av stor nytteverdi i denne prosessen. Funnene i oppgaven påpekte sykepleierens allsidige rolle i å identifisere og ivareta foreldrene og barnets individuelle behov. For å kunne dekke dette behovet var kommunikasjon og medbestemmelse, samt støtte i å mestre foreldrerollen av tillitsbyggende betydning. Nøkkelord: Sykepleie, barn, tillit, samhandling, foreldre, foreldreinvolvering, sykehu

The Prognostic Impact of Protein Expression of E-Cadherin-Catenin Complexes Differs between Rectal and Colon Carcinoma

The E-cadherin-catenin complex provides cell-cell adhesion. In order for a carcinoma to metastasize, cancer cells must let go of their hold of neighboring cells in the primary tumor. The presence of components of the E-cadherin-catenin complex in 246 rectal adenocarcinomas was examined by immunohistochemistry and compared to their presence in 219 colon carcinomas. The expression data were correlated to clinical information from the patients' records. There were statistically significant differences in protein expression between the rectal and the colon carcinomas regarding membranous β-catenin, γ-catenin, p120-catenin, and E-cadherin, as well as nuclear β-catenin. In the rectal carcinomas, there was a significant inverse association between the expression of p120-catenin in cell membranes of the primary tumors and the occurrence of local recurrence, while membranous protein expression of β-catenin was inversely related to distant metastases

Differences in Protein Expression and Gene Amplification of Cyclins between Colon and Rectal Adenocarcinomas

Adenocarcinomas of rectum and colon may be different with regard to the cellular biological basis for cancer development. A material of 246 rectal cancers removed surgically at Akershus University Hospital in the years 1992–2000 was investigated and was compared to a material of 219 colon cancers operated on at Akershus University Hospital during the years 1988, 1990 and 1997–2000. There were highly significant differences between the rectal and the colon cancers in the protein expression of cyclin D1, cyclin D3, cyclin E, nuclear β-catenin, and c-Myc and in gene amplification of cyclin A2, cyclin B1, cyclin D1, and cyclin E. Gene amplification and protein expression in the rectal cancers correlated significantly for the cyclins B1, D3, and E. A statistically significant relation was observed between overexpression of cyclin A2 and local relapse of rectal carcinomas, as higher expression of cyclin A2 was associated with lower local recurrence rate

Being “on the alert” and “a forced volunteer”: a qualitative study of the invisible care provided by the next of kin of patients with chronic heart failure

Background: Relatives’ support is an important factor in how well people with chronic heart failure (CHF) manage their illness and everyday life. Deepening professionals' understanding of the content of relatives’ invisible care activities, often characterized as care burden, is necessary to strengthen support services. Objective: To explore the next of kin’s experiences of invisible care and the inherent responsibilities in caring for a relative with CHF. Design, setting, and methods: Relatives were recruited from CHF outpatient clinics and home care services. Seventeen women and two men were interviewed, age range 45–83 years; 12 were partners, and seven were daughters. The qualitative interviews were taped and transcribed and thematic cross-case analyses were performed. Results: Two main themes were revealed. The first, “being on the alert”, refers to a perceived need, real or assumed, to be aware day and night, whether present with the patient or not, that occupies the mind, emotions, and body. The second theme, “being a forced volunteer”, refers to two different dimensions: relatives'’ own perceptions of responsibility with regard to the patient's needs; and voiced or silent expectations from the patient, family members, and health personnel that the relative will help the patient. Both findings appeared to have positive and negative impacts on the relationship with the patient. Conclusion: The identified themes reflect how challenging being a next of kin of CHF patients can be. The results may deepen professionals’ understanding of the relatives’ invisible care burden and the importance of their subjective task-related feelings. More studies on invisible care and the attendant responsibilities are needed and also on relatives’ inherent resources

Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomy

Background: The aim of this study was to ascertain the impact of injury to the superior mesenteric nerve plexus caused by right colectomy with D3 extended mesenterectomy as performed in the prospective multicenter trial: “Safe Radical D3 Right Hemicolectomy for Cancer through Preoperative Biphasic Multi-detector Computed Tomography” in which all soft tissue surrounding the superior mesenteric vessels from the level of the middle colic artery to that of the ileocolic artery was removed. Methods: Bowel function and gastrointestinal quality of life in two consecutive cohorts that underwent right colectomy with and without D3 extended mesenterectomy were compared. Main outcome measures were the Diarrhea Assessment Scale (DAS) and Gastrointestinal Quality of Life Index (GIQLI). The data were collected prospectively through telephone interviews. Results: Forty-nine patients per group, comparable for age, sex, length of bowel resected but with significantly shorter follow-up time in the experimental group, were included. There was no difference in total DAS scores, subscores or additional questions except for higher bowel frequency scores in the D3 group (p = 0.02). Comparison of total GIQLI scores and subscales showed no difference between groups. Regression analysis with correction for confounding factors showed 0.48 lower bowel frequency scores in the D2 group (p = 0.022). Within the D3 group presence of jejunal arteries cranial to the D3 dissection area showed 1.78 lower DAS scores and 0.7 lower bowel frequency scores. Conclusions: Small bowel denervation after right colectomy with D3 extended mesenterectomy leads to increased bowel frequency but does not impact gastrointestinal quality of life. Individual anatomical variants can affect postoperative bowel function differently despite standardized surgery.acceptedVersio