Constraints on the neutron star equation of state from AT2017gfo using radiative transfer simulations

The detection of the binary neutron star GW170817 together with the observation of electromagnetic counterparts across the entire spectrum inaugurated a new era of multi-messenger astronomy. In this study we incorporate wavelength-dependent opacities and emissivities calculated from atomic-structure data enabling us to model both the measured lightcurves and spectra of the electromagnetic transient AT2017gfo. Best-fits of the observational data are obtained by Gaussian Process Regression, which allows us to present posterior samples for the kilonova and source properties connected to GW170817. Incorporating constraints obtained from the gravitational wave signal obtained by the LIGO-Virgo Scientific Collaboration, we present a $90\%$ upper bound on the mass ratio $q \lesssim 1.38$ and a lower bound on the tidal deformability of $\tilde{\Lambda} \gtrsim 197$, which rules out sufficiently soft equations of state. Our analysis is a path-finder for more realistic kilonova models and shows how the combination of gravitational wave and electromagnetic measurements allow for stringent constraints on the source parameters and the supranuclear equation of state

X-ray spectroscopy of NGC 5548

We analyze the high-resolution X-ray spectrum of the Seyfert 1 galaxy NGC 5548, for the full 0.1-10 keV band, using improved calibration results of the Chandra-LETGS instrument. The warm absorber consists of at least three ionization components, namely one with a low, medium and high ionization parameter. The X-ray absorbing material, from an outflowing wind, covers the full range of velocity components found from UV absorption lines. The presence of redshifted emission components for the strongest blue-shifted resonance absorption lines indicate that the absorber is located at a distance larger than the edge of the accretion disk. We derive an upper limit to the edge of the accretion disk of 1 light year. Absorption lines from ions of at least ten chemical elements have been detected, and in general for these elements there are no strong deviations from solar abundances. The narrow emission lines from the O VII and Ne IX forbidden and intercombination lines probably originate from much larger distances to the black hole. We find evidence for weak relativistically broadened oxygen and nitrogen emission lines from the inner parts of the accretion disk, but at a much smaller flux level than those observed in some other active galactic nuclei. In addition, there is a broad, non-relativistic C VI Ly alpha emission line that is consistent with emission lines from the inner part of the optical/UV broad line region.Comment: 18 pages, 19 figures, accepted for publication in Astronomy and Astrophysic

Reconstructing genome evolution in historic samples of the Irish potato famine pathogen

Responsible for the Irish potato famine of 1845–49, the oomycete pathogen Phytophthora infestans caused persistent, devastating outbreaks of potato late blight across Europe in the 19th century. Despite continued interest in the history and spread of the pathogen, the genome of the famine-era strain remains entirely unknown. Here we characterize temporal genomic changes in introduced P. infestans. We shotgun sequence five 19th-century European strains from archival herbarium samples—including the oldest known European specimen, collected in 1845 from the first reported source of introduction. We then compare their genomes to those of extant isolates. We report multiple distinct genotypes in historical Europe and a suite of infection-related genes different from modern strains. At virulence-related loci, several now-ubiquitous genotypes were absent from the historical gene pool. At least one of these genotypes encodes a virulent phenotype in modern strains, which helps explain the 20th century’s episodic replacements of European P. infestans lineages

Constraints on the neutron star equation of state from AT2017gfo using radiative transfer simulations

The detection of the binary neutron star merger GW170817 together with the observation of electromagnetic counterparts across the entire spectrum inaugurated a new era of multimessenger astronomy. In this study, we incorporate wavelength-dependent opacities and emissivities calculated from atomic-structure data enabling us to model both the measured light curves and spectra of the electromagnetic transient AT2017gfo. Best fits of the observational data are obtained by Gaussian Process Regression, which allows us to present posterior samples for the kilonova and source properties connected to GW170817. Incorporating constraints obtained from the gravitational wave signal measured by the LIGO-Virgo Scientific Collaboration, we present a 90 per cent upper bound on the mass ratio q ≲ 1.38 and a lower bound on the tidal deformability of Λ ≳ 197, which rules out sufficiently soft equations of state. Our analysis is a path-finder for more realistic kilonova models and shows how the combination of gravitational wave and electromagnetic measurements allow for stringent constraints on the source parameters and the supranuclear equation of state

UNLOCKing creative & innovative teaching in higher education extended abstracts

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Elevated visual dependency in young adults after chemotherapy in childhood

Chemotherapy in childhood can result in long-term neurophysiological side-effects, which could extend to visual processing, specifically the degree to which a person relies on vision to determine vertical and horizontal (visual dependency). We investigated whether adults treated with chemotherapy in childhood experience elevated visual dependency compared to controls and whether any difference is associated with the age at which subjects were treated. Visual dependency was measured in 23 subjects (mean age 25.3 years) treated in childhood with chemotherapy (CTS) for malignant, solid, non-CNS tumors. We also stratified CTS into two groups: those treated before 12 years of age and those treated from 12 years of age and older. Results were compared to 25 healthy, age-matched controls. The subjective visual horizontal (SVH) and vertical (SVV) orientations was recorded by having subjects position an illuminated rod to their perceived horizontal and vertical with and without a surrounding frame tilted clockwise and counter-clockwise 20° from vertical. There was no significant difference in rod accuracy between any CTS groups and controls without a frame. However, when assessing visual dependency using a frame, CTS in general (p = 0.006) and especially CTS treated before 12 years of age (p = 0.001) tilted the rod significantly further in the direction of the frame compared to controls. Our findings suggest that chemotherapy treatment before 12 years of age is associated with elevated visual dependency compared to controls, implying a visual bias during spatial activities. Clinicians should be aware of symptoms such as visual vertigo in adults treated with chemotherapy in childhood

Global, regional, and national burden of chronic kidney disease, 1990–2017 : a systematic analysis for the Global Burden of Disease Study 2017

Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. Methods The main data sources we used were published literature, vital registration systems, end-stage kidney disease registries, and household surveys. Estimates of CKD burden were produced using a Cause of Death Ensemble model and a Bayesian meta-regression analytical tool, and included incidence, prevalence, years lived with disability, mortality, years of life lost, and disability-adjusted life-years (DALYs). A comparative risk assessment approach was used to estimate the proportion of cardiovascular diseases and gout burden attributable to impaired kidney function. Findings Globally, in 2017, 1·2 million (95% uncertainty interval [UI] 1·2 to 1·3) people died from CKD. The global all-age mortality rate from CKD increased 41·5% (95% UI 35·2 to 46·5) between 1990 and 2017, although there was no significant change in the age-standardised mortality rate (2·8%, −1·5 to 6·3). In 2017, 697·5 million (95% UI 649·2 to 752·0) cases of all-stage CKD were recorded, for a global prevalence of 9·1% (8·5 to 9·8). The global all-age prevalence of CKD increased 29·3% (95% UI 26·4 to 32·6) since 1990, whereas the age-standardised prevalence remained stable (1·2%, −1·1 to 3·5). CKD resulted in 35·8 million (95% UI 33·7 to 38·0) DALYs in 2017, with diabetic nephropathy accounting for almost a third of DALYs. Most of the burden of CKD was concentrated in the three lowest quintiles of Socio-demographic Index (SDI). In several regions, particularly Oceania, sub-Saharan Africa, and Latin America, the burden of CKD was much higher than expected for the level of development, whereas the disease burden in western, eastern, and central sub-Saharan Africa, east Asia, south Asia, central and eastern Europe, Australasia, and western Europe was lower than expected. 1·4 million (95% UI 1·2 to 1·6) cardiovascular disease-related deaths and 25·3 million (22·2 to 28·9) cardiovascular disease DALYs were attributable to impaired kidney function. Interpretation Kidney disease has a major effect on global health, both as a direct cause of global morbidity and mortality and as an important risk factor for cardiovascular disease. CKD is largely preventable and treatable and deserves greater attention in global health policy decision making, particularly in locations with low and middle SDI

An X-ray Baldwin effect for the narrow Fe K-alpha lines observed in Active Galactic Nuclei

The majority of Active Galactic Nuclei (AGN) observed by XMM-Newton reveal narrow Fe K-alpha lines at ~ 6.4 keV, due to emission from cold (neutral) material. There is an X-ray Baldwin effect in Type I AGN, in that the equivalent width of the line decreases with increasing luminosity, with weighted linear regression giving EW ~ L^{-0.17+/-0.08} (Spearman Rank probability of > 99.9%). With current instrumental capabilities it is not possible to determine the precise origin for the narrow line, with both the Broad Line Region and putative molecular torus being possibilities. A possible explanation for the X-ray Baldwin effect is a decrease in covering factor of the material forming the fluorescence line.Comment: 8 pages, 6 figures, accepted by MNRA

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration